Quan He

Summary

Affiliation: Henry Ford Hospital
Country: USA

Publications

  1. doi request reprint Tafazzin knockdown causes hypertrophy of neonatal ventricular myocytes
    Quan He
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202 2689, USA
    Am J Physiol Heart Circ Physiol 299:H210-6. 2010
  2. pmc PKA, Rap1, ERK1/2, and p90RSK mediate PGE2 and EP4 signaling in neonatal ventricular myocytes
    Quan He
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI 48202 2689, USA
    Am J Physiol Heart Circ Physiol 298:H136-43. 2010
  3. ncbi request reprint Left ventricular targeting of reporter gene expression in vivo by human BNP promoter in an adenoviral vector
    Margot C LaPointe
    Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Am J Physiol Heart Circ Physiol 283:H1439-45. 2002
  4. pmc Female adult mouse cardiomyocytes are protected against oxidative stress
    Fangfei Wang
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, 2799 West Grand Blvd, Detroit, MI 48202 2689, USA
    Hypertension 55:1172-8. 2010
  5. pmc Lack of microsomal prostaglandin E synthase-1 reduces cardiac function following angiotensin II infusion
    Pamela Harding
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Am J Physiol Heart Circ Physiol 300:H1053-61. 2011
  6. ncbi request reprint Glycogen synthase kinase-3 is required for optimal de novo synthesis of inositol
    Abed N Azab
    Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA
    Mol Microbiol 63:1248-58. 2007
  7. doi request reprint Loss of tafazzin in yeast leads to increased oxidative stress during respiratory growth
    Shuliang Chen
    Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA
    Mol Microbiol 68:1061-72. 2008
  8. pmc Gene expression profiling of dilated cardiomyopathy in older male EP4 knockout mice
    Pamela Harding
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan, USA
    Am J Physiol Heart Circ Physiol 298:H623-32. 2010
  9. ncbi request reprint Augmented healing process in female mice with acute myocardial infarction
    Fangfei Wang
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, and Department of Biology, Wayne State University, Detroit, Michigan 48202 2689, USA
    Gend Med 4:230-47. 2007
  10. ncbi request reprint Regulation of the human brain natriuretic peptide gene by GATA-4
    Quan He
    Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Am J Physiol Endocrinol Metab 283:E50-7. 2002

Collaborators

Detail Information

Publications11

  1. doi request reprint Tafazzin knockdown causes hypertrophy of neonatal ventricular myocytes
    Quan He
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202 2689, USA
    Am J Physiol Heart Circ Physiol 299:H210-6. 2010
    ..Taken together, our data support the concept that a decreased tafazzin expression causes cardiomyocyte hypertrophy in vitro...
  2. pmc PKA, Rap1, ERK1/2, and p90RSK mediate PGE2 and EP4 signaling in neonatal ventricular myocytes
    Quan He
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI 48202 2689, USA
    Am J Physiol Heart Circ Physiol 298:H136-43. 2010
    ..We conclude that EP4-dependent signaling in NVMs in part involves PKA, Rap, ERK1/2, and p90RSK and results in the increased expression of brain natriuretic peptide and c-Fos...
  3. ncbi request reprint Left ventricular targeting of reporter gene expression in vivo by human BNP promoter in an adenoviral vector
    Margot C LaPointe
    Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Am J Physiol Heart Circ Physiol 283:H1439-45. 2002
    ..Thus the use of the proximal hBNP promoter in recombinant adenoviral vectors may allow cardiac-specific and inducible expression of therapeutic genes in vivo and prevent some of the side effects of systemic adenovirus administration...
  4. pmc Female adult mouse cardiomyocytes are protected against oxidative stress
    Fangfei Wang
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, 2799 West Grand Blvd, Detroit, MI 48202 2689, USA
    Hypertension 55:1172-8. 2010
    ..This may be attributable to activation of Akt and inhibition of GSK-3beta and caspase 3 through an estrogen receptor-alpha-mediated mechanism...
  5. pmc Lack of microsomal prostaglandin E synthase-1 reduces cardiac function following angiotensin II infusion
    Pamela Harding
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Am J Physiol Heart Circ Physiol 300:H1053-61. 2011
    ..Overall, these results are consistent with a beneficial effect for mPGES-1 in the maintenance of cardiac function in ANG II-dependent hypertension...
  6. ncbi request reprint Glycogen synthase kinase-3 is required for optimal de novo synthesis of inositol
    Abed N Azab
    Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA
    Mol Microbiol 63:1248-58. 2007
    ..These results demonstrate for the first time that GSK-3 is required for optimal myo-inositol-3 phosphate synthase activity and de novo inositol biosynthesis, and that loss of GSK-3 activity causes inositol depletion...
  7. doi request reprint Loss of tafazzin in yeast leads to increased oxidative stress during respiratory growth
    Shuliang Chen
    Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA
    Mol Microbiol 68:1061-72. 2008
    ..Our findings of increased oxidative stress in the taz1Delta mutant during respiratory growth may have important implications for understanding the pathogenesis of Barth syndrome...
  8. pmc Gene expression profiling of dilated cardiomyopathy in older male EP4 knockout mice
    Pamela Harding
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan, USA
    Am J Physiol Heart Circ Physiol 298:H623-32. 2010
    ..Early overexpression of GDF-15 in hearts of male KO mice may contribute to or be a marker of the disease phenotype. The absence of serious cardiac dysfunction in aged female mice suggests a sexual dimorphism in the phenotype...
  9. ncbi request reprint Augmented healing process in female mice with acute myocardial infarction
    Fangfei Wang
    Hypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, and Department of Biology, Wayne State University, Detroit, Michigan 48202 2689, USA
    Gend Med 4:230-47. 2007
    ....
  10. ncbi request reprint Regulation of the human brain natriuretic peptide gene by GATA-4
    Quan He
    Hypertension and Vascular Research Division, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Am J Physiol Endocrinol Metab 283:E50-7. 2002
    ..Thus the GATA element in the proximal hBNP promoter is involved in both basal and inducible transcriptional regulation in cardiac myocytes...
  11. ncbi request reprint Post-translational regulation of phosphatidylglycerolphosphate synthase in response to inositol
    Quan He
    Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA
    Mol Microbiol 53:1243-9. 2004
    ..This is the first evidence of phosphorylation of a phospholipid biosynthetic enzyme in response to inositol and identifies a new mechanism of inositol-mediated regulation...