S Goldstein

Summary

Affiliation: Henry Ford Hospital
Country: USA

Publications

  1. doi request reprint Phase 2 study of TAK-442, an oral factor Xa inhibitor, in patients following acute coronary syndrome
    Sidney Goldstein
    Sidney Goldstein, MD, 2799 West Grand Blvd, Detroit, MI 48202, USA, Tel 1 313 916 2727, Fax 1 313 916 8416, E mail
    Thromb Haemost 111:1141-52. 2014
  2. pmc Debate: Do all patients with heart failure require automatic implantable defibrillators for the prevention of sudden death?
    Sidney Goldstein
    Henry Ford Hospital, Detroit, Michigan, and Case Western Reserve University, Cleveland, Ohio, USA
    Curr Control Trials Cardiovasc Med 1:95-97. 2000
  3. ncbi request reprint The changing epidemiology of sudden death in heart failure
    Sidney Goldstein
    Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, 2799 West Grand Boulevard, Detroit, MI 48202, USA
    Curr Heart Fail Rep 1:93-7. 2004
  4. ncbi request reprint Beta blocker therapy in African American patients with heart failure
    Sidney Goldstein
    Henry Ford Hospital, 2799 West Grand Blvd, Detroit, Michigan 48202, USA
    Heart Fail Rev 9:161-7. 2004
  5. ncbi request reprint Metoprolol CR/XL in black patients with heart failure (from the Metoprolol CR/XL randomized intervention trial in chronic heart failure)
    Sidney Goldstein
    Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, Michigan 48202, USA
    Am J Cardiol 92:478-80. 2003
  6. ncbi request reprint Benefits of beta-blocker therapy for heart failure: weighing the evidence
    Sidney Goldstein
    Division of Cardiovascular Medicine, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA
    Arch Intern Med 162:641-8. 2002
  7. ncbi request reprint Metoprolol controlled release/extended release in patients with severe heart failure: analysis of the experience in the MERIT-HF study
    S Goldstein
    Henry Ford Heart and Vascular Institute, Henry Ford Hospital, Detroit, Michigan 48202 2689, USA
    J Am Coll Cardiol 38:932-8. 2001
  8. ncbi request reprint Programmed cell death in the progression of heart failure
    H N Sabbah
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, MI 48202, USA
    Ann Med 30:33-8. 1998
  9. ncbi request reprint Effects of dopamine beta-hydroxylase inhibition with nepicastat on the progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure
    H N Sabbah
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, MI, USA
    Circulation 102:1990-5. 2000
  10. ncbi request reprint Heart failure therapy at the turn of the century
    S Goldstein
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Medicine, Detroit, Michigan, USA
    Heart Fail Rev 6:7-14. 2001

Collaborators

Detail Information

Publications38

  1. doi request reprint Phase 2 study of TAK-442, an oral factor Xa inhibitor, in patients following acute coronary syndrome
    Sidney Goldstein
    Sidney Goldstein, MD, 2799 West Grand Blvd, Detroit, MI 48202, USA, Tel 1 313 916 2727, Fax 1 313 916 8416, E mail
    Thromb Haemost 111:1141-52. 2014
    ..There was no evidence for efficacy. ..
  2. pmc Debate: Do all patients with heart failure require automatic implantable defibrillators for the prevention of sudden death?
    Sidney Goldstein
    Henry Ford Hospital, Detroit, Michigan, and Case Western Reserve University, Cleveland, Ohio, USA
    Curr Control Trials Cardiovasc Med 1:95-97. 2000
    ..This medical approach is beneficial to all patients, and should be our major therapy. However, it is reasonable to attempt to identify that subpopulations of heart failure patients who could benefit from an ICD...
  3. ncbi request reprint The changing epidemiology of sudden death in heart failure
    Sidney Goldstein
    Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, 2799 West Grand Boulevard, Detroit, MI 48202, USA
    Curr Heart Fail Rep 1:93-7. 2004
    ..Sudden death has become a larger issue and the dominant mode of death in heart failure. This change requires the clinician to redirect therapy to the prevention and treatment of sudden death...
  4. ncbi request reprint Beta blocker therapy in African American patients with heart failure
    Sidney Goldstein
    Henry Ford Hospital, 2799 West Grand Blvd, Detroit, Michigan 48202, USA
    Heart Fail Rev 9:161-7. 2004
    ..In that study there appeared to be a unique differential effect in African Americans compared to Caucasians which may have been in part related to the severity of the disease...
  5. ncbi request reprint Metoprolol CR/XL in black patients with heart failure (from the Metoprolol CR/XL randomized intervention trial in chronic heart failure)
    Sidney Goldstein
    Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, Michigan 48202, USA
    Am J Cardiol 92:478-80. 2003
    ..Results suggest a beneficial effect of beta blockade and support the use of beta blockers in black patients with clinically stable heart failure and left ventricular dysfunction...
  6. ncbi request reprint Benefits of beta-blocker therapy for heart failure: weighing the evidence
    Sidney Goldstein
    Division of Cardiovascular Medicine, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA
    Arch Intern Med 162:641-8. 2002
    ..Critical evaluation of the evidence from basic research studies, as well as clinical trials in patients with heart failure, helps to delineate the theoretical and clinical benefits of beta-blockers...
  7. ncbi request reprint Metoprolol controlled release/extended release in patients with severe heart failure: analysis of the experience in the MERIT-HF study
    S Goldstein
    Henry Ford Heart and Vascular Institute, Henry Ford Hospital, Detroit, Michigan 48202 2689, USA
    J Am Coll Cardiol 38:932-8. 2001
    ..This study analyzed the effect of the beta(1)-selective beta-blocker metoprolol succinate controlled release/extended release (CR/XL) once daily on mortality, hospitalizations and tolerability in patients with severe heart failure...
  8. ncbi request reprint Programmed cell death in the progression of heart failure
    H N Sabbah
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, MI 48202, USA
    Ann Med 30:33-8. 1998
    ....
  9. ncbi request reprint Effects of dopamine beta-hydroxylase inhibition with nepicastat on the progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure
    H N Sabbah
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, MI, USA
    Circulation 102:1990-5. 2000
    ....
  10. ncbi request reprint Heart failure therapy at the turn of the century
    S Goldstein
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Medicine, Detroit, Michigan, USA
    Heart Fail Rev 6:7-14. 2001
    ....
  11. ncbi request reprint Cardiac contractility modulation with the impulse dynamics signal: studies in dogs with chronic heart failure
    H N Sabbah
    Department of Medicine and Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, Michigan USA
    Heart Fail Rev 6:45-53. 2001
    ..Additional, long-term studies in dogs with heart failure are needed to establish the safety and efficacy of this therapeutic modality for the chronic treatment of this disease syndrome...
  12. ncbi request reprint Effect of delay on racial differences in thrombolysis for acute myocardial infarction
    M Syed
    Henry Ford Heart and Vascular Institute, Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, Michigan, USA
    Am Heart J 140:643-50. 2000
    ..To analyze the effect of delay times on racial differences in thrombolysis for acute myocardial infarction...
  13. ncbi request reprint Chronic therapy with metoprolol attenuates cardiomyocyte apoptosis in dogs with heart failure
    H N Sabbah
    Department of Medicine, Henry Ford Heart and Vascular Institute, Detroit, Michigan, USA
    J Am Coll Cardiol 36:1698-705. 2000
    ..The purpose of this study was to determine if therapy with beta-blockade is associated with reduced cardiomyocyte apoptosis...
  14. ncbi request reprint Use of beta-blockers in congestive heart failure
    John A Sallach
    Cleveland Clinic Foundation, Cleveland, OH, USA
    Ann Med 35:259-66. 2003
    ....
  15. ncbi request reprint A COMET lost
    Sidney Goldstein
    Ital Heart J 4:653-4. 2003
  16. ncbi request reprint How should subgroup analyses affect clinical practice? Insights from the Metoprolol Succinate Controlled-Release/Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF)
    John Wikstrand
    Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska University Hospital, Goteborg, Sweden
    Card Electrophysiol Rev 7:264-75. 2003
    ....
  17. ncbi request reprint Selective versus nonselective beta-blockade for heart failure therapy: are there lessons to be learned from the COMET trial?
    Michael R Bristow
    Division of Cardiology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Card Fail 9:444-53. 2003
    ....
  18. ncbi request reprint Consistency of the beneficial effect of metoprolol succinate extended release across a wide range dose of angiotensin-converting enzyme inhibitors and digitalis
    Jalal K Ghali
    Cardiac Centers of Louisiana, 2551 Greenwood Road, Suite 350, Shreveport, LA 71103, USA
    J Card Fail 10:452-9. 2004
    ....
  19. ncbi request reprint The COMET trial
    Michael R Bristow
    Division of Cardiology, University of Colorado Health Sciences Center, B130, Room 6430, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Congest Heart Fail 11:39-47. 2005
  20. ncbi request reprint Effects of long-term monotherapy with metoprolol CR/XL on the progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure
    Hideaki Morita
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, MI, USA
    Cardiovasc Drugs Ther 16:443-9. 2002
    ..The benefits are fully attributable to beta-blockade alone as no other adjunctive therapy was used...
  21. ncbi request reprint Beta blockers as cardioprotective agents: Part II--Focus on prevention of sudden cardiac death
    Sidney Goldstein
    Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, Michigan, USA
    Am J Manag Care 8:18-24. 2002
  22. ncbi request reprint Dose of metoprolol CR/XL and clinical outcomes in patients with heart failure: analysis of the experience in metoprolol CR/XL randomized intervention trial in chronic heart failure (MERIT-HF)
    John Wikstrand
    Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska University Hospital, Goteborg, Sweden
    J Am Coll Cardiol 40:491-8. 2002
    ....
  23. ncbi request reprint Cardiac contractility modulation with nonexcitatory electric signals improves left ventricular function in dogs with chronic heart failure
    Hideaki Morita
    Departments of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Henry Ford Health System, Detroit, Michigan 48202, USA
    J Card Fail 9:69-75. 2003
    ..In this study, we examined the effects of CCM signal delivery on left ventricular function in dogs with chronic heart failure (HF)...
  24. ncbi request reprint Effect of long-term monotherapy with the aldosterone receptor blocker eplerenone on cytoskeletal proteins and matrix metalloproteinases in dogs with heart failure
    Sharad Rastogi
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Health System, Detroit, MI 48202, USA
    Cardiovasc Drugs Ther 21:415-22. 2007
    ....
  25. ncbi request reprint Chronic monotherapy with rosuvastatin prevents progressive left ventricular dysfunction and remodeling in dogs with heart failure
    Valerio Zaca
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Henry Ford Health System, Detroit, Michigan, USA
    J Am Coll Cardiol 50:551-7. 2007
    ..This study examined the effects of long-term monotherapy with rosuvastatin (RSV) on the progression of left ventricular (LV) dysfunction and remodeling in dogs with heart failure (HF)...
  26. ncbi request reprint Globalization of cardiovascular clinical research: the balance between meeting medical needs and maintaining scientific standards
    Wendy Gattis Stough
    Department of Clinical Research Campbell University School of Pharmacy, Research Triangle Park, NC, USA
    Am Heart J 154:232-8. 2007
    ..These and other issues are critical to address as the conduct of cardiovascular clinical trials continues to expand beyond the western world...
  27. pmc Left atrial reverse remodeling in dogs with moderate and advanced heart failure treated with a passive mechanical containment device: an echocardiographic study
    Valerio Zaca
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, Michigan 48202, USA
    J Card Fail 13:312-7. 2007
    ..This study examined the effects of the CSD on global LA remodeling in dogs with moderate and advanced HF...
  28. ncbi request reprint Associations of gender and etiology with outcomes in heart failure with systolic dysfunction: a pooled analysis of 5 randomized control trials
    Camille G Frazier
    Division of Cardiovascular Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Am Coll Cardiol 49:1450-8. 2007
    ..This study sought to explore the gender-related differences in etiology and outcomes in chronic heart failure (HF) patients from 5 randomized trials...
  29. ncbi request reprint Selective matrix metalloproteinase inhibition attenuates progression of left ventricular dysfunction and remodeling in dogs with chronic heart failure
    Hideaki Morita
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA
    Am J Physiol Heart Circ Physiol 290:H2522-7. 2006
    ..In conclusion, in dogs with moderate HF, long-term monotherapy with HD selective MMP inhibitor PG prevents LV remodeling and the progression of global LV dysfunction...
  30. ncbi request reprint Beta-blockers in the post-myocardial infarction patient
    Mihai Gheorghiade
    Division of Cardiology, Northwestern Feinberg Medical School, Chicago, Ill 60611, USA
    Circulation 106:394-8. 2002
  31. ncbi request reprint Echocardiographic predictors of prognosis after first acute myocardial infarction
    Omar Obeidat
    Henry Ford Heart and Vascular Institute, Detroit, Michigan 48202, USA
    Am J Cardiol 94:1278-80. 2004
    ....
  32. ncbi request reprint Sudden death in heart failure: underlying electrophysiological mechanisms
    Subramaniam C Krishnan
    The Heart and Vascular Institute, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48202, USA
    Heart Fail Rev 7:255-60. 2002
  33. ncbi request reprint Long-term effects of non-excitatory cardiac contractility modulation electric signals on the progression of heart failure in dogs
    Hideaki Morita
    Department of Medicine, Henry Ford Heart and Vascular Institute, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA
    Eur J Heart Fail 6:145-50. 2004
    ..In the present study we examined the long-term effects of CCM signal delivery on the progression of LV dysfunction and remodeling in dogs with chronic HF...
  34. ncbi request reprint Effects of chronic neutral endopeptidase inhibition on the progression of left ventricular dysfunction and remodeling in dogs with moderate heart failure
    Takayuki Mishima
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, 2799 W Grand Boulevard, Detroit, MI 48202, USA
    Cardiovasc Drugs Ther 16:209-14. 2002
    ..The present study investigates the effects of long-term NEP inhibition on the progression of left ventricular (LV) dysfunction and remodeling in dogs with moderate heart failure...
  35. ncbi request reprint Effects of pre-existing left ventricular hypertrophy on ventricular dysfunction and remodeling following myocardial infarction in rats
    Omar Nass
    Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, Michigan 48202, USA
    J Heart Lung Transplant 21:1113-9. 2002
    ..In the present study, we examine the effects of pre-existing left ventricular hypertrophy (LVH) on LV function and chamber enlargement following MI in inbred Lewis rats...
  36. ncbi request reprint Effects of long-term monotherapy with eplerenone, a novel aldosterone blocker, on progression of left ventricular dysfunction and remodeling in dogs with heart failure
    George Suzuki
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, Mich, USA
    Circulation 106:2967-72. 2002
    ..Eplerenone is a novel selective aldosterone blocker. The present study examined the effects of long-term monotherapy with eplerenone on the progression of LV dysfunction and remodeling in dogs with chronic HF...
  37. pmc Effects of the AT1-receptor antagonist eprosartan on the progression of left ventricular dysfunction in dogs with heart failure
    George Suzuki
    Department of Medicine, Division of Cardiovascular Medicine, Henry Ford Heart and Vascular Institute, Detroit, Michigan 48202, U S A
    Br J Pharmacol 138:301-9. 2003
    ..4. We conclude that eprosartan prevents progressive LV dysfunction and attenuates progressive LV remodelling in dogs with moderate HF and may be useful in treating patients with chronic HF...
  38. ncbi request reprint ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult: executive summary
    Sharon A Hunt
    American College of Cardiology American Heart Association Task Force on Practice Guidelines
    J Heart Lung Transplant 21:189-203. 2002