Hideo Watanabe

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Hopping between differentiation states in lung adenocarcinoma
    Hideo Watanabe
    Department of Medical Oncology, Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA
    Cancer Cell 23:707-9. 2013
  2. doi request reprint Dynamic epigenetic regulation by menin during pancreatic islet tumor formation
    Wenchu Lin
    Department of Medical Oncology, Center for Cancer Genome Discovery, Dana Farber Cancer Institute, Boston, Massachusetts Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts High Magnetic Field Laboratory, Chinese Academy of Sciences, 350 Shushanhu RD, Hefei, Anhui Province, 230031, P R China
    Mol Cancer Res 13:689-98. 2015
  3. pmc Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers
    Xiaoyang Zhang
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Nat Genet 48:176-82. 2016
  4. pmc Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target
    Hideo Watanabe
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA
    Genes Dev 27:197-210. 2013

Collaborators

  • Shouyong Peng
  • Xiaoyang Zhang
  • JOSHUA M FRANCIS
  • Matthew Meyerson
  • Wenchu Lin
  • Peter S Choi
  • Andrew D Cherniack
  • Marcin Imielinski
  • Aruna Ramachandran
  • Chandra Sekhar Pedamallu
  • NATHAN KAPLAN
  • Agoston Agoston
  • Adam J Bass

Detail Information

Publications5

  1. pmc Hopping between differentiation states in lung adenocarcinoma
    Hideo Watanabe
    Department of Medical Oncology, Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA
    Cancer Cell 23:707-9. 2013
    ..The work by Cheung and colleagues, in this issue of Cancer Cell, demonstrates another example of how lineage-specific transcriptional regulators of differentiation, GATA6 and HOPX, can control the fate of lung adenocarcinoma progression...
  2. doi request reprint Dynamic epigenetic regulation by menin during pancreatic islet tumor formation
    Wenchu Lin
    Department of Medical Oncology, Center for Cancer Genome Discovery, Dana Farber Cancer Institute, Boston, Massachusetts Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts High Magnetic Field Laboratory, Chinese Academy of Sciences, 350 Shushanhu RD, Hefei, Anhui Province, 230031, P R China
    Mol Cancer Res 13:689-98. 2015
    ..Taken together, these data demonstrate that loss of Men1 in pancreatic islet cells alters the epigenetic landscape of its target genes...
  3. pmc Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers
    Xiaoyang Zhang
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Nat Genet 48:176-82. 2016
    ..Our results suggest that genomic amplification of super-enhancers represents a common mechanism to activate cancer driver genes in multiple cancer types. ..
  4. pmc Integrated cistromic and expression analysis of amplified NKX2-1 in lung adenocarcinoma identifies LMO3 as a functional transcriptional target
    Hideo Watanabe
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA
    Genes Dev 27:197-210. 2013
    ..Our findings provide new insight into the transcriptional regulatory network of NKX2-1 and suggest that LMO3 is a transcriptional signal transducer in NKX2-1-amplified lung adenocarcinomas...