Linda J Van Marter
Affiliation: Harvard University
- Nonsteroidal antiinflammatory drugs in late pregnancy and persistent pulmonary hypertension of the newbornLinda J Van Marter
Boston Children s Hospital, Boston, Massachusetts 02115, USA
Pediatrics 131:79-87. 2013..This study was designed to test the hypothesis that risk for PPHN is increased after antenatal exposure to nonsteroidal antiinflammatory drugs (NSAIDs), with particular emphasis on late gestational exposures...
- Epidemiology of bronchopulmonary dysplasiaLinda J Van Marter
Children s Hospital and Brigham and Women s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Semin Fetal Neonatal Med 14:358-66. 2009....
- Does bronchopulmonary dysplasia contribute to the occurrence of cerebral palsy among infants born before 28 weeks of gestation?Linda J Van Marter
Newborn Medicine, Children s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
Arch Dis Child Fetal Neonatal Ed 96:F20-9. 2011..To evaluate the relationships among cerebral palsy (CP) phenotypes and bronchopulmonary dysplasia (BPD) severity and, in the process, to generate hypotheses regarding causal pathways linking BPD to CP...
- Progress in discovery and evaluation of treatments to prevent bronchopulmonary dysplasiaLinda J Van Marter
Children s Hospital, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
Biol Neonate 89:303-12. 2006..To date, clinical trials have failed to demonstrate a substantial benefit of a single treatment or preventive strategy for BPD...
- Antenatal antecedents of a small head circumference at age 24-months post-term equivalent in a sample of infants born before the 28th post-menstrual weekAlan Leviton
Department of Neurology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
Early Hum Dev 86:515-21. 2010..Little is known about the antecedents of microcephaly in early childhood among children born at extremely low gestational age...
- The clustering of disorders in infants born before the 28th week of gestationAlan Leviton
Neurology Department, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
Acta Paediatr 99:1795-800. 2010..To see whether disorders prevalent in infants born extremely preterm cluster...
- Blood protein concentrations in the first two postnatal weeks associated with early postnatal blood gas derangements among infants born before the 28th week of gestation. The ELGAN StudyAlan Leviton
Department of Neurology, Children s Hospital Boston, and Harvard Medical School, Boston, MA 02115, USA
Cytokine 56:392-8. 2011..To explore the relationships between blood gas derangements and blood concentrations of inflammation-related proteins shortly after preterm birth...
- Early blood gas abnormalities and the preterm brainAlan Leviton
Neuroepidemiology Unit, Neurology Department, Children s Hospital Boston, and Harvard Medical School, Boston, Massachusetts 02215 5724, USA
Am J Epidemiol 172:907-16. 2010..Findings suggest that individual blood gas derangements do not increase brain damage risk. Rather, the multiple derangements associated with indicators of brain damage might be indicators of immaturity/vulnerability and illness severity...
- Urinary intestinal fatty acid binding protein predicts necrotizing enterocolitisKatherine E Gregory
W F Connell School of Nursing, Boston College, Chestnut Hill, MA Department of Nursing, Brigham and Women s Hospital, Boston, MA Department of Newborn Medicine, Brigham and Women s Hospital, Boston, MA Electronic address
J Pediatr 164:1486-8. 2014..In seeking a predictive biomarker, we found intestinal fatty acid binding protein, an indicator of enterocyte damage, was substantially increased within three and seven days before the diagnosis of necrotizing enterocolitis. ..
- Maternal antenatal complications and the risk of neonatal cerebral white matter damage and later cerebral palsy in children born at an extremely low gestational ageThomas F McElrath
Division of Maternal Fetal Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
Am J Epidemiol 170:819-28. 2009....
- Chorioamnionitis, mechanical ventilation, and postnatal sepsis as modulators of chronic lung disease in preterm infantsLinda J Van Marter
Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
J Pediatr 140:171-6. 2002..This case-control study of chronic lung disease (CLD) evaluated the hypothesis that chorioamnionitis promotes CLD and interacts with other risk factors for CLD, including mechanical ventilation and postnatal infection...
- Antenatal glucocorticoids increase early total thyroxine levels in premature infantsCamilia R Martin
Department of Neonatology, Beth Israel Deaconess Medical Center, Division of Newborn Medicine, Boston, MA 02215, USA
Biol Neonate 87:273-80. 2005..It is standard obstetrical practice to offer antenatal glucocorticoids to pregnant women with threatened preterm delivery. Few studies have investigated the effect of antenatal glucocorticoids on neonatal thyroid function...
- Presumed and definite bacteremia in extremely low gestational age newbornsSonal Patel
Floating Hospital for Children at Tufts Medical Center, Boston, MA 02111, USA
Acta Paediatr 100:36-41. 2011..To explore risk patterns for presumed and definite, early and late neonatal bacteremia...
- The relationship between TSH and systemic inflammation in extremely preterm newbornsCarmen L Soto-Rivera
Department of Medicine, Divisions of Endocrinology and Medicine Critical Care, Boston Children s Hospital, Harvard Medical School, Boston, MA, USA
Endocrine 48:595-602. 2015..Our findings more prominently support the hypothesis that TSH conveys information about concomitant inflammation in the extremely premature newborn. ..
- Low urine vascular endothelial growth factor levels are associated with mechanical ventilation, bronchopulmonary dysplasia and retinopathy of prematurityBernadette M Levesque
Division of Newborn Medicine, Boston Children s Hospital, Boston, Mass, USA
Neonatology 104:56-64. 2013..Urine VEGF is easily measured and useful in early diagnosis of several diseases...
- Colonization of second-trimester placenta parenchymaAndrew B Onderdonk
Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
Am J Obstet Gynecol 199:52.e1-52.e10. 2008..The overtly healthy, nonpregnant uterus harbors bacteria, Mycoplasma and Ureaplasma. The extent of colonization remains elusive, as are relationships between isolated microorganisms, preterm labor and fetal inflammation...
- Risk factors for persistent pulmonary hypertension of the newbornSonia Hernandez-Diaz
Slone Epidemiology Center at Boston University, 1010 Commonwealth Ave, Boston, MA 02215, USA
Pediatrics 120:e272-82. 2007..We performed a case-control study to determine possible antenatal and perinatal predictors of persistent pulmonary hypertension of the newborn...
- Perturbation of gene expression of the chromatin remodeling pathway in premature newborns at risk for bronchopulmonary dysplasiaJennifer Cohen
Children s Hospital, Boston, Division of Newborn Medicine, Boston, Longwood Avenue, Boston, MA 02115, USA
Genome Biol 8:R210. 2007..Sections of umbilical cord were obtained at birth from 20 infants who later developed BPD and from 34 of their peers who did not develop BPD...
- Fetal placental thrombosis and neonatal implicationsPia Wintermark
Division of Newborn Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
Am J Perinatol 27:251-6. 2010..Severe fetal placental vascular lesions seem to be a predisposing factor for some adverse neonatal outcomes. We present these two cases with a brief review of the literature...
- Urine bombesin-like peptide elevation precedes clinical evidence of bronchopulmonary dysplasiaAnne Cullen
Children s Hospital, Department of Pathology, Boston, Massachusetts 02115, USA
Am J Respir Crit Care Med 165:1093-7. 2002..Utilizing urine bombesin-like peptide for screening might permit early therapeutic interventions to reduce disease progression and could provide a target for new preventive therapies...
- Strategies for preventing bronchopulmonary dysplasiaLinda J Van Marter
Children s Hospital and Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Curr Opin Pediatr 17:174-80. 2005..The purpose of this review is to highlight recent reports of a number of potential treatments intended to prevent BPD and to discuss the controversies surrounding preventive strategies...
- Early postnatal blood concentrations of inflammation-related proteins and microcephaly two years later in infants born before the 28th post-menstrual weekAlan Leviton
Children s Hospital Boston, Boston MA 02115 5724, United States
Early Hum Dev 87:325-30. 2011..To evaluate if concentrations of inflammation-related proteins were elevated in early postnatal blood specimens of preterm newborns who two years later had a small head...
- Peak-to-peak amplitude in neonatal brain monitoring of premature infantsDeirdre O'Reilly
Children s Hospital Boston, Newborn Medicine, Boston, MA, USA
Clin Neurophysiol 123:2139-53. 2012..To assess the strength of association between alternative measures of electroencephalographic (EEG) signal peak-to-peak amplitude (ppA) and postmenstrual age (PMA) among a cohort of extremely premature infants...
- Stooling pattern and early nutritional exposures associated with necrotizing enterocolitis in premature infantsKatherine E Gregory
Departments of Pediatric Newborn Medicine and Nursing, Brigham and Women s Hospital, Boston, Massachusetts
J Perinat Neonatal Nurs 29:60-8. 2015..While further analyses may be needed, clinical suspicion for NEC should not be overwhelmingly influenced by the stooling pattern observed during the early neonatal period. ..
- Pregnancy disorders that lead to delivery before the 28th week of gestation: an epidemiologic approach to classificationT F McElrath
Division of Maternal Fetal Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Am J Epidemiol 168:980-9. 2008..Disorders leading to preterm delivery may be separated into two groups: those associated with intrauterine inflammation and those associated with aberrations of placentation...
- Systemic hypotension and white-matter damage in preterm infantsOlaf Dammann
Children s Hospital, Boston, MA 02115, USA
Dev Med Child Neurol 44:82-90. 2002..In sum, these results do not support the hypothesis that systemic hypotension contributes to echolucency among preterm infants...
- Vitamin D status among preterm and full-term infants at birthHeather H Burris
1 Harvard Medical School, Boston, Massachusetts 2 Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 3 Division of Newborn Medicine, Boston Children s Hospital, Boston, Massachusetts
Pediatr Res 75:75-80. 2014..We aimed to determine the associations between 25(OH)D levels and gestational age...
- Endotoxin-directed innate immunity in tracheal aspirates of mechanically ventilated human neonatesKatheryn E Nathe
Department of Medicine, Children s Hospital Boston, Boston, Massachusetts 02115, USA
Pediatr Res 66:191-6. 2009..TA extracellular BPI, LBP, and sCD14 were positively correlated. TAs from intubated neonates demonstrate endotoxin accumulation and mobilization of endotoxin-directed innate immunity, potentially contributing to pulmonary inflammation...
- Risk of cranial ultrasound abnormalities in very-low-birth-weight infants conceived with assisted reproductive techniquesJane E Stewart
Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
J Perinatol 22:37-45. 2002....
- Bronchopulmonary dysplasia is not associated with ultrasound-defined cerebral white matter damage in preterm newbornsOlaf Dammann
Department of Obstetrics, Prenatal Medicine and Gynecology, Hannover Medical School, 30623 Hannover, Germany
Pediatr Res 55:319-25. 2004..Confounding does not seem to account for this lack of association between WMD and BPD. In conclusion, our findings do not support the hypothesis that BPD contributes to the occurrence of sonographically defined WMD...
- Factors associated with treatment for hypotension in extremely low gestational age newborns during the first postnatal weekMatthew Laughon
School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Pediatrics 119:273-80. 2007....
- Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newbornChristina D Chambers
Department of Pediatrics, University of California, San Diego, La Jolla, CA 92103, USA
N Engl J Med 354:579-87. 2006..We performed a case-control study to assess whether PPHN is associated with exposure to SSRIs during late pregnancy...