N S Trede

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Fishing for lymphoid genes
    N S Trede
    Division of Hematology, Children s Hospital and Howard Hughes Medical Institute, 320 Longwood Avenue, Boston, MA 02115, USA
    Trends Immunol 22:302-7. 2001
  2. doi request reprint Evolutionarily conserved and divergent regions of the autoimmune regulator (Aire) gene: a comparative analysis
    Mark Saltis
    Department of Microbiology and Immunology, University of Maryland, Baltimore, MD 21201, USA
    Immunogenetics 60:105-14. 2008
  3. pmc Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110
    Nikolaus S Trede
    Institute of Biochemistry, Justus Liebig University, D 35392 Giessen, Germany
    Proc Natl Acad Sci U S A 104:6608-13. 2007
  4. ncbi request reprint Mitoferrin is essential for erythroid iron assimilation
    George C Shaw
    Division of Hematology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 440:96-100. 2006
  5. pmc Resolution of the novel immune-type receptor gene cluster in zebrafish
    Jeffrey A Yoder
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
    Proc Natl Acad Sci U S A 101:15706-11. 2004
  6. pmc The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis
    David G Ransom
    Division of Hematology Oncology, Children s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    PLoS Biol 2:E237. 2004
  7. ncbi request reprint The use of zebrafish to understand immunity
    Nikolaus S Trede
    Division of Pediatric Oncology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115 USA
    Immunity 20:367-79. 2004
  8. ncbi request reprint Cloning and characterization of an Mx gene and its corresponding promoter from the zebrafish, Danio rerio
    Stephen M Altmann
    Department of Biochemistry, Microbiology, and Molecular Biology, University of Maine, Orono, ME 04469, USA
    Dev Comp Immunol 28:295-306. 2004
  9. ncbi request reprint Myc-induced T cell leukemia in transgenic zebrafish
    David M Langenau
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    Science 299:887-90. 2003
  10. ncbi request reprint Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish
    Eric C Liao
    Division of Hematology Oncology, Children s Hospital, Department of Pediatrics and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA
    Development 129:649-59. 2002

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Fishing for lymphoid genes
    N S Trede
    Division of Hematology, Children s Hospital and Howard Hughes Medical Institute, 320 Longwood Avenue, Boston, MA 02115, USA
    Trends Immunol 22:302-7. 2001
    ..Studies of the zebrafish should improve our understanding of lymphoid development in vertebrates...
  2. doi request reprint Evolutionarily conserved and divergent regions of the autoimmune regulator (Aire) gene: a comparative analysis
    Mark Saltis
    Department of Microbiology and Immunology, University of Maryland, Baltimore, MD 21201, USA
    Immunogenetics 60:105-14. 2008
    ..These findings reveal a very rapid evolution of certain regions of aire during vertebrate evolution and support the existence of an aire-dependent mechanism of T cell tolerance dating back at least to the emergence of bony fish...
  3. pmc Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110
    Nikolaus S Trede
    Institute of Biochemistry, Justus Liebig University, D 35392 Giessen, Germany
    Proc Natl Acad Sci U S A 104:6608-13. 2007
    ..Together, our data demonstrate that a mutation in a general splicing factor can lead to distinct defects in organ development and cause disease...
  4. ncbi request reprint Mitoferrin is essential for erythroid iron assimilation
    George C Shaw
    Division of Hematology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Nature 440:96-100. 2006
    ..Our data show that mfrn functions as the principal mitochondrial iron importer essential for haem biosynthesis in vertebrate erythroblasts...
  5. pmc Resolution of the novel immune-type receptor gene cluster in zebrafish
    Jeffrey A Yoder
    Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough Street, Raleigh, NC 27606, USA
    Proc Natl Acad Sci U S A 101:15706-11. 2004
    ..These studies resolve a complete immune gene cluster in zebrafish and indicate that the NITRs represent the most complex family of activating/inhibitory surface receptors thus far described...
  6. pmc The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis
    David G Ransom
    Division of Hematology Oncology, Children s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    PLoS Biol 2:E237. 2004
    ..Our results establish a major role for this transcriptional intermediary factor in the differentiation of hematopoietic cells in vertebrates...
  7. ncbi request reprint The use of zebrafish to understand immunity
    Nikolaus S Trede
    Division of Pediatric Oncology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115 USA
    Immunity 20:367-79. 2004
    ..Here, we discuss the advent of the zebrafish as a powerful vertebrate model organism that promises to positively impact immunologic research...
  8. ncbi request reprint Cloning and characterization of an Mx gene and its corresponding promoter from the zebrafish, Danio rerio
    Stephen M Altmann
    Department of Biochemistry, Microbiology, and Molecular Biology, University of Maine, Orono, ME 04469, USA
    Dev Comp Immunol 28:295-306. 2004
    ....
  9. ncbi request reprint Myc-induced T cell leukemia in transgenic zebrafish
    David M Langenau
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    Science 299:887-90. 2003
    ..This transgenic model provides a platform for drug screens and for genetic screens aimed at identifying mutations that suppress or enhance c-myc- induced carcinogenesis...
  10. ncbi request reprint Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish
    Eric C Liao
    Division of Hematology Oncology, Children s Hospital, Department of Pediatrics and Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA
    Development 129:649-59. 2002
    ..These observations demonstrate that the bls gene product is uniquely required in a non-cell autonomous manner for primitive hematopoiesis, potentially acting via regulation of scl...
  11. pmc In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish
    David M Langenau
    Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA 02115
    Proc Natl Acad Sci U S A 101:7369-74. 2004
    ..By contrast, whole kidney marrow permanently reconstituted the T lymphoid compartment of irradiated wild-type fish, suggesting that long-term thymic repopulating cells reside in the kidney...
  12. ncbi request reprint The zebrafish as a model organism to study development of the immune system
    David Traver
    Division of Hematology, Children s Hospital, 320, Longwood Avenue, Boston, MA 02115, USA
    Adv Immunol 81:253-330. 2003
  13. ncbi request reprint Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency
    Barry H Paw
    Department of Medicine, Division of Hematology Oncology, Children s Hospital, Boston, Massachusetts, USA
    Nat Genet 34:59-64. 2003
    ..1R-binding domains. Our report establishes an evolutionarily conserved role for band 3 in erythroid-specific cell division and illustrates the concept of cell-specific adaptation for mitosis...
  14. ncbi request reprint Method for isolation of PCR-ready genomic DNA from zebrafish tissues
    Nathan D Meeker
    Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA
    Biotechniques 43:610, 612, 614. 2007
    ..Given its speed and low cost, we anticipate that the adoption of this method will streamline DNA isolation for zebrafish research...
  15. doi request reprint Immunology and zebrafish: spawning new models of human disease
    Nathan D Meeker
    The Department of Pediatrics and the Huntsman Cancer Institute, University of Utah, Suite 4265, 2000 Circle of Hope, Salt Lake City, UT 84112, USA
    Dev Comp Immunol 32:745-57. 2008
    ..Models of immune system malignancies are discussed that are either based on oncogene over-expression or on our own forward-genetic screen that was designed to identify new models of immune dysregulation...
  16. doi request reprint Views on four key questions about zebrafish research
    Keith C Cheng
    Jake Gittlen Cancer Research Foundation, Penn State College of Medicine, Hershey, Pennsylvania 17033, USA
    Zebrafish 5:9-24. 2008