Rulla M Tamimi

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Comparison of estrogen receptor results from pathology reports with results from central laboratory testing
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    J Natl Cancer Inst 100:218-21. 2008
  2. ncbi request reprint Endogenous hormone levels, mammographic density, and subsequent risk of breast cancer in postmenopausal women
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 99:1178-87. 2007
  3. pmc Insulin-like growth factor-1, insulin-like growth factor binding protein-3 and lobule type in the Nurses' Health Study II
    Megan S Rice
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave 3rd Floor, Boston, MA, 02115 USA
    Breast Cancer Res 14:R44. 2012
  4. pmc Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer
    Jingmei Li
    Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden
    Breast Cancer Res 12:R19. 2010
  5. pmc Common ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case-control study
    Rulla M Tamimi
    Program in Molecular and Genetic Epidemiology, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Breast Cancer Res 6:R416-22. 2004
  6. pmc Alcohol intake between menarche and first pregnancy: a prospective study of breast cancer risk
    Ying Liu
    Affiliations of authors Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St Louis, MO YL, GAC Alvin J Siteman Cancer Center at Barnes Jewish Hospital and Washington University School of Medicine, St Louis, MO GAC Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA BR, CSB, WYC, RMT Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA LCC, SJS, JLC Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA WCW
    J Natl Cancer Inst 105:1571-8. 2013
  7. pmc Genetic variation and circulating levels of IGF-I and IGFBP-3 in relation to risk of proliferative benign breast disease
    Xuefen Su
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 126:180-90. 2010
  8. ncbi request reprint The influence of family history on breast cancer risk in women with biopsy-confirmed benign breast disease: results from the Nurses' Health Study
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Cancer 107:1240-7. 2006
  9. pmc Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma
    Brenda M Birmann
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 18:282-8. 2009
  10. doi request reprint Birth weight, breast cancer susceptibility loci, and breast cancer risk
    Rulla M Tamimi
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Causes Control 21:689-96. 2010

Detail Information

Publications86

  1. pmc Comparison of estrogen receptor results from pathology reports with results from central laboratory testing
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    J Natl Cancer Inst 100:218-21. 2008
    ..78, P < .001). Thus, ER assay results from pathology reports appear to be a reasonable alternative to central laboratory ER testing for large, population-based studies of patients with breast cancer...
  2. ncbi request reprint Endogenous hormone levels, mammographic density, and subsequent risk of breast cancer in postmenopausal women
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 99:1178-87. 2007
    ..Whether mammographic density reflects levels of endogenous sex hormones is unclear. We examined whether these predictors are independently associated with breast cancer risk in a prospective study...
  3. pmc Insulin-like growth factor-1, insulin-like growth factor binding protein-3 and lobule type in the Nurses' Health Study II
    Megan S Rice
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave 3rd Floor, Boston, MA, 02115 USA
    Breast Cancer Res 14:R44. 2012
    ..Studies in animal models suggest that insulin-like growth factor-1 (IGF-1) may inhibit involution of lobules in the breast; however, this has not been studied in humans...
  4. pmc Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer
    Jingmei Li
    Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, Stockholm, Sweden
    Breast Cancer Res 12:R19. 2010
    ..In this study, we evaluate the association between mammographic density and genetic variants of the estrogen metabolic pathway...
  5. pmc Common ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case-control study
    Rulla M Tamimi
    Program in Molecular and Genetic Epidemiology, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Breast Cancer Res 6:R416-22. 2004
    ..Five biallelic haplotype tagging single nucleotide polymorphisms are estimated to capture 99% of the haplotype diversity in Caucasian populations...
  6. pmc Alcohol intake between menarche and first pregnancy: a prospective study of breast cancer risk
    Ying Liu
    Affiliations of authors Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St Louis, MO YL, GAC Alvin J Siteman Cancer Center at Barnes Jewish Hospital and Washington University School of Medicine, St Louis, MO GAC Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA BR, CSB, WYC, RMT Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA LCC, SJS, JLC Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA WCW
    J Natl Cancer Inst 105:1571-8. 2013
    ..No study has characterized the contribution of alcohol consumption during this interval to risks of proliferative benign breast disease (BBD) and breast cancer...
  7. pmc Genetic variation and circulating levels of IGF-I and IGFBP-3 in relation to risk of proliferative benign breast disease
    Xuefen Su
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 126:180-90. 2010
    ..These results suggest that genetic variants and circulating levels of IGFBP-3 may play a role in the early stage of breast carcinogenesis...
  8. ncbi request reprint The influence of family history on breast cancer risk in women with biopsy-confirmed benign breast disease: results from the Nurses' Health Study
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Cancer 107:1240-7. 2006
    ..However, the influence of a positive family history (FH) on breast cancer risk among women with biopsy-confirmed BBD is less certain...
  9. pmc Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma
    Brenda M Birmann
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 18:282-8. 2009
    ..Nonetheless, the data are consistent with the hypothesis that IGF-1- and IL-6-related gene variation influences susceptibility to multiple myeloma and warrant confirmation in larger populations...
  10. doi request reprint Birth weight, breast cancer susceptibility loci, and breast cancer risk
    Rulla M Tamimi
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Causes Control 21:689-96. 2010
    ....
  11. pmc Reproductive factors and risk of premenopausal breast cancer by age at diagnosis: are there differences before and after age 40?
    Erica T Warner
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Breast Cancer Res Treat 142:165-75. 2013
    ..However, associations between reproductive factors and risk of breast cancer were similar regardless of age at diagnosis of premenopausal breast cancer...
  12. pmc Vegetable protein and vegetable fat intakes in pre-adolescent and adolescent girls, and risk for benign breast disease in young women
    Catherine S Berkey
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Breast Cancer Res Treat 141:299-306. 2013
    ..In conclusion, consumption of vegetable protein, fat, peanut butter, or nuts by older girls may help reduce their risk of BBD as young women...
  13. pmc Columnar cell lesions and subsequent breast cancer risk: a nested case-control study
    Sarah A Aroner
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res 12:R61. 2010
    ..However, the risk of subsequent breast cancer associated with the presence of CCL in a benign breast biopsy is poorly understood...
  14. pmc Breast cancer susceptibility loci and mammographic density
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA
    Breast Cancer Res 10:R66. 2008
    ....
  15. pmc Expression of IGF1R in normal breast tissue and subsequent risk of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Breast Cancer Res Treat 128:243-50. 2011
    ..Further studies to confirm these findings are necessary...
  16. ncbi request reprint Manganese superoxide dismutase polymorphism, plasma antioxidants, cigarette smoking, and risk of breast cancer
    Rulla M Tamimi
    Department ofEpidemiology, Harvard School of Public Health, Boston, MA, USA
    Cancer Epidemiol Biomarkers Prev 13:989-96. 2004
    ..41; 95% confidence interval 0.77-2.60; P for interaction = 0.03). These data suggest that the Ala allele of MnSOD may modify breast cancer risk among current smokers, but is not an independent risk factor for breast cancer...
  17. pmc Metabolic syndrome and mammographic density in Mexican women
    Megan S Rice
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Cancer Prev Res (Phila) 6:701-10. 2013
    ..These findings provide some support for a possible role of metabolic syndrome in mammographic density among premenopausal women; however, results were inconsistent across states and require further confirmation in larger studies...
  18. pmc Circulating carotenoids and risk of breast cancer: pooled analysis of eight prospective studies
    A Heather Eliassen
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 104:1905-16. 2012
    ..Most, but not all, past studies of circulating carotenoids and breast cancer have found an inverse association with at least one carotenoid, although the specific carotenoid has varied across studies...
  19. pmc Time to diagnosis and breast cancer stage by race/ethnicity
    Erica T Warner
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    Breast Cancer Res Treat 136:813-21. 2012
    ..Longer time to diagnosis did not fully explain differences in stage between racial/ethnicity groups...
  20. pmc Traditional breast cancer risk factors in relation to molecular subtypes of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res Treat 131:159-67. 2012
    ..Identifying risk factors for less common subtypes such as luminal B, HER2-type and basal-like tumors has important implications for prevention of these more aggressive subtypes...
  21. pmc Young women with family history of breast cancer and their risk factors for benign breast disease
    Catherine S Berkey
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 118:2796-803. 2012
    ..The authors investigated childhood/adolescent risk factors for benign breast disease (BBD), a well-documented risk factor for BC, among girls with a family history...
  22. pmc Body size across the life course, mammographic density, and risk of breast cancer
    Holly R Harris
    Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Boston, MA 02115, USA
    Am J Epidemiol 174:909-18. 2011
    ..Conversely, mammographic density does not appear to explain the inverse association between childhood and adolescent body fatness and breast cancer risk...
  23. pmc Lobule type and subsequent breast cancer risk: results from the Nurses' Health Studies
    Heather J Baer
    Division of General Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
    Cancer 115:1404-11. 2009
    ..Lobules in normal breast tissue can be classified based on their degree of development, which may affect their susceptibility to carcinogenesis. However, few epidemiologic studies to date have addressed this...
  24. pmc Nondense mammographic area and risk of breast cancer
    Andreas Pettersson
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res 13:R100. 2011
    ..We investigated separately the absolute dense area and the absolute nondense area on mammograms in relation to breast cancer risk...
  25. pmc Vitamin D-related genetic variation, plasma vitamin D, and risk of lethal prostate cancer: a prospective nested case-control study
    Irene M Shui
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02215, USA
    J Natl Cancer Inst 104:690-9. 2012
    ..The association of vitamin D status with prostate cancer is controversial; no association has been observed for overall incidence, but there is a potential link with lethal disease...
  26. pmc Gene x Gene interaction between MnSOD and GPX-1 and breast cancer risk: a nested case-control study
    David G Cox
    Program in Molecular and Genetic Epidemiology, Epidemiology Department, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    BMC Cancer 6:217. 2006
    ..We investigated whether variants at both polymorphisms, while not independently associated with breast cancer risk, could influence breast cancer risk when considered together...
  27. pmc Intake of fiber and nuts during adolescence and incidence of proliferative benign breast disease
    Xuefen Su
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, 3rd Floor, Boston, MA 02115, USA
    Cancer Causes Control 21:1033-46. 2010
    ..We examined the association between adolescent fiber intake and proliferative BBD, a marker of increased breast cancer risk, in the Nurses' Health Study II...
  28. pmc Androgen receptor expression and breast cancer survival in postmenopausal women
    Rong Hu
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Clin Cancer Res 17:1867-74. 2011
    ..However, the association between tumor AR status and breast cancer survival is uncertain. Hence, we examined the association between AR status and breast cancer survival in the Nurses' Health Study (NHS)...
  29. ncbi request reprint Magnitude and laterality of breast cancer risk according to histologic type of atypical hyperplasia: results from the Nurses' Health Study
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Cancer 109:180-7. 2007
    ..Atypical hyperplasia (AH) in a benign breast biopsy is associated with an increased breast cancer risk. However, the influence of the histologic type of AH on the magnitude and laterality of breast cancer risk is poorly defined...
  30. pmc Prospective study of growth and development in older girls and risk of benign breast disease in young women
    Catherine S Berkey
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 117:1612-20. 2011
    ..The authors prospectively evaluated these childhood/adolescent characteristics and BBD risk...
  31. pmc Genome-wide association scans for secondary traits using case-control samples
    Genevieve M Monsees
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Genet Epidemiol 33:717-28. 2009
    ....
  32. pmc Breast cancer risk prediction with heterogeneous risk profiles according to breast cancer tumor markers
    Bernard Rosner
    Channing Division of Network Medicine, Brigham andWomen s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Epidemiol 178:296-308. 2013
    ..This approach provides a strategy for evaluating heterogeneity of risk factor associations by tumor marker levels while controlling for additional tumor markers. ..
  33. pmc Radial scars and subsequent breast cancer risk: results from the Nurses' Health Studies
    Sarah A Aroner
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Breast Cancer Res Treat 139:277-85. 2013
    ..Larger studies are needed to further evaluate whether risk is increased when multiple RS are present and whether associations vary by age at biopsy or by hormone receptor status of the breast tumor...
  34. pmc COX-2 expression predicts worse breast cancer prognosis and does not modify the association with aspirin
    Michelle D Holmes
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res Treat 130:657-62. 2011
    ..The survival benefit associated with aspirin use did not differ by COX-2 status. COX-2 breast cancer expression is associated with worse prognosis. If aspirin truly impacts breast cancer survival, then it is not solely via COX-2...
  35. pmc Estrogen receptor-beta expression in invasive breast cancer in relation to molecular phenotype: results from the Nurses' Health Study
    Jonathan D Marotti
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Mod Pathol 23:197-204. 2010
    ..The role of ER-beta in the development and progression of breast cancers defined by lack of expression of ER-alpha merits further investigation...
  36. pmc Potential role of tissue microarrays for the study of biomarker expression in benign breast disease and normal breast tissue
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Appl Immunohistochem Mol Morphol 17:438-41. 2009
    ..Whether or not TMAs may also be a potentially useful platform for assessing biomarkers in benign proliferative breast lesions (BPBL) and normal breast tissue has not been previously studied in detail...
  37. pmc Comparison of molecular phenotypes of ductal carcinoma in situ and invasive breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA
    Breast Cancer Res 10:R67. 2008
    ..The purpose of this study was to compare the prevalence of these distinct molecular subtypes among cases of DCIS and invasive breast cancer...
  38. pmc Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res 9:R18. 2007
    ....
  39. pmc Prospective study of adolescent alcohol consumption and risk of benign breast disease in young women
    Catherine S Berkey
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Pediatrics 125:e1081-7. 2010
    ..To investigate prospectively, using alcoholic beverage consumption data collected in real time, the association between adolescent drinking and risk of biopsy-confirmed benign breast disease (BBD) in young women...
  40. pmc Height and Body Size in Childhood, Adolescence, and Young Adulthood and Breast Cancer Risk According to Molecular Subtype in the Nurses' Health Studies
    Erica T Warner
    Clinical Translational Epidemiology Unit, Massachusetts General Hospital, Boston, Massachusetts Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, Massachusetts Channing Division of Network Medicine, Brigham and Women s Hospital, Boston, Massachusetts
    Cancer Prev Res (Phila) 9:732-8. 2016
    ..Cancer Prev Res; 9(9); 732-8. ©2016 AACR. ..
  41. pmc Treatment-related amenorrhea and sexual functioning in young breast cancer survivors
    Shoshana M Rosenberg
    Harvard School of Public Health, Boston, Massachusetts Dana Farber Cancer Institute, Boston, Massachusetts
    Cancer 120:2264-71. 2014
    ..However, few studies have explored how treatment and other factors affect sexual functioning in young breast cancer survivors...
  42. doi request reprint Breast cancer presentation and diagnostic delays in young women
    Kathryn J Ruddy
    Dana Farber Cancer Institute, Boston, Massachusetts
    Cancer 120:20-5. 2014
    ..Young women may experience delays in diagnosis of breast cancer, and these delays may contribute to poorer outcomes...
  43. pmc Body size throughout the life course and mammographic density in Mexican women
    Megan S Rice
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Breast Cancer Res Treat 138:601-10. 2013
    ..e., before first pregnancy and ages 25-35) and percent MD among postmenopausal women is inconsistent with prior research and requires confirmation in other studies...
  44. pmc High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer
    Sandro Santagata
    Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 108:18378-83. 2011
    ..The findings indicate that HSF1 should be evaluated prospectively as an independent prognostic indicator in ER-positive breast cancer. HSF1 may ultimately be a useful therapeutic target in cancer...
  45. pmc A prospective study of genetic polymorphism in MPO, antioxidant status, and breast cancer risk
    Chunyan He
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Breast Cancer Res Treat 113:585-94. 2009
    ..Further research is needed to confirm these possible associations...
  46. pmc Evaluation of a breast cancer risk prediction model expanded to include category of prior benign breast disease lesion
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 116:4944-53. 2010
    ..Given the substantial heterogeneity in breast cancer risk dependent on the type of benign lesion, the authors evaluated whether incorporating this level of detail would improve the discriminatory power of risk classification models...
  47. ncbi request reprint Plasma carotenoids, retinol, and tocopherols and risk of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Epidemiol 161:153-60. 2005
    ..Although the association was strongest for alpha-carotene, the high degree of collinearity among plasma carotenoids limits our ability to conclude that this association is specific to any individual carotenoid...
  48. pmc BRCA1 and BRCA2 Mutation Testing in Young Women With Breast Cancer
    Shoshana M Rosenberg
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts
    JAMA Oncol 2:730-6. 2016
    ..BRCA testing is recommended for young women diagnosed as having breast cancer, but little is known about decisions surrounding testing and how results may influence treatment decisions in young patients...
  49. pmc Expression of estrogen receptor, progesterone receptor, and Ki67 in normal breast tissue in relation to subsequent risk of breast cancer
    Hannah Oh
    Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA Channing Division of Network Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA Department of Nutrition, Harvard T H Chan School of Public Health, Boston, MA, USA
    NPJ Breast Cancer 2:. 2016
    ..However, given the small sample size, further studies are required to confirm these results...
  50. pmc Adolescent dietary vitamin D and sun exposure in relation to benign breast disease
    Caroline E Boeke
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA
    Cancer Causes Control 26:1181-7. 2015
    ..In the Nurses' Health Study II, higher recalled adolescent vitamin D intake was associated with a lower risk of benign breast disease (BBD). Our study aimed to assess adolescent vitamin D exposure in relation to BBD in young women...
  51. pmc Local Therapy Decision-Making and Contralateral Prophylactic Mastectomy in Young Women with Early-Stage Breast Cancer
    Shoshana M Rosenberg
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    Ann Surg Oncol 22:3809-15. 2015
    ..Rates of contralateral prophylactic mastectomy (CPM) have increased in the United States, with younger women with breast cancer the most likely to have CPM...
  52. pmc Dietary Fat and Fiber Intakes Are Not Associated with Patterns of Urinary Estrogen Metabolites in Premenopausal Women
    Hannah Oh
    Department of Epidemiology, Department of Nutrition, and Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA
    J Nutr 145:2109-16. 2015
    ..Interindividual differences in the bioavailability of potentially carcinogenic estrogen and estrogen metabolites (EMs) may play a role in the risk of breast cancer...
  53. pmc Postmenopausal mammographic breast density and subsequent breast cancer risk according to selected tissue markers
    Lusine Yaghjyan
    Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, 2004 Mowry Road, Gainesville, FL 32610, USA
    Br J Cancer 113:1104-13. 2015
    ..This study aimed to determine if associations of pre-diagnostic percent breast density, absolute dense area, and non-dense area with subsequent breast cancer risk differ by the tumour's molecular marker status...
  54. pmc Dietary fat intake in relation to lethal breast cancer in two large prospective cohort studies
    Caroline E Boeke
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA
    Breast Cancer Res Treat 146:383-92. 2014
    ....
  55. pmc Dairy intakes in older girls and risk of benign breast disease in young women
    Catherine S Berkey
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 22:670-4. 2013
    ..We conclude that dairy intakes by older girls have no strong relation with BBD risk in young women. Because of small number of cases, it is important to continue follow-up and re-examine later...
  56. pmc A nonparametric test to detect quantitative trait loci where the phenotypic distribution differs by genotypes
    Hugues Aschard
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Genet Epidemiol 37:323-33. 2013
    ..We demonstrate the potential utility of our method on real data by analyzing mammographic density genome-wide data from the Nurses' Health Study...
  57. pmc Estrogen receptor positive tumors: do reproductive factors explain differences in incidence between black and white women?
    Erica T Warner
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Cancer Causes Control 24:731-9. 2013
    ..In two large prospective cohorts, the Black Women's Health Study (BWHS) and the Nurses' Health Study II (NHSII), we investigated whether reproductive factors explain the difference...
  58. pmc Insulin-like growth factor-1, insulin-like growth factor-binding protein-3, growth hormone, and mammographic density in the Nurses' Health Studies
    Megan S Rice
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Breast Cancer Res Treat 136:805-12. 2012
    ..Overall, plasma IGF-1, IGFBP-3, and GH levels were not associated with mammographic density in a sample of premenopausal and postmenopausal women...
  59. pmc Androgen receptor expression in breast cancer in relation to molecular phenotype: results from the Nurses' Health Study
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Mod Pathol 24:924-31. 2011
    ..Our findings raise the possibility that targeting the androgen receptor pathway may represent a novel therapeutic approach to the management of patients with basal-like cancers...
  60. ncbi request reprint A prospective study of XRCC1 haplotypes and their interaction with plasma carotenoids on breast cancer risk
    Jiali Han
    Department of Nutrition, Harvard Center for Cancer Prevention, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer Res 63:8536-41. 2003
    ....
  61. pmc Plasma 25-Hydroxyvitamin D and Risk of Breast Cancer in Women Followed over 20 Years
    A Heather Eliassen
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, Massachusetts
    Cancer Res 76:5423-30. 2016
    ..Cancer Res; 76(18); 5423-30. ©2016 AACR. ..
  62. pmc Adult body size and physical activity in relation to risk of breast cancer according to tumor androgen receptor status
    Xuehong Zhang
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts
    Cancer Epidemiol Biomarkers Prev 24:962-8. 2015
    ..Obesity and physical activity have been hypothesized to affect breast cancer risk partly via the androgen signaling pathway. We conducted the first study to evaluate these associations by tumor androgen receptor (AR) status...
  63. pmc Adolescent carotenoid intake and benign breast disease
    Caroline E Boeke
    Departments of Epidemiology and Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts
    Pediatrics 133:e1292-8. 2014
    ..Exposure to carotenoids may be most important during adolescence when breast tissue is still developing. We examined adolescent carotenoid intake in relation to BBD in young women...
  64. pmc Prognosis in women with interval breast cancer: population based observational cohort study
    Mette Kalager
    Department of Epidemiology, Harvard School of Public Health, Boston, USA
    BMJ 345:e7536. 2012
    ....
  65. ncbi request reprint The HRAS1 variable number of tandem repeats and risk of breast cancer
    Rulla M Tamimi
    Department of Epidemiology, Harvard School of Public Health, and Channing Laboratory, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 12:1528-30. 2003
    ..These results suggest that there is no overall association between rare alleles of the HRAS1 VNTR and breast cancer...
  66. pmc Circulating colony stimulating factor-1 and breast cancer risk
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Res 68:18-21. 2008
    ..45; 95% CI, 1.02-2.07; P(trend) = 0.06) and ER+/PR+ tumors (RR, 1.72; 95% CI, 1.11-2.66; P(trend) = 0.04). Thus, the association of circulating CSF1 levels and breast cancer varies by menopausal status...
  67. pmc Circulating carotenoids, mammographic density, and subsequent risk of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 69:9323-9. 2009
    ..05). Our results suggest that plasma levels of carotenoids may play a role in reducing breast cancer risk, particularly among women with high mammographic density...
  68. pmc Mammographic density, plasma vitamin D levels and risk of breast cancer in postmenopausal women
    Angela K Green
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 127:667-74. 2010
    ..Further research examining vitamin D, mammographic density and breast cancer risk is warranted...
  69. pmc Benign breast disease, recent alcohol consumption, and risk of breast cancer: a nested case-control study
    Rulla M Tamimi
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Breast Cancer Res 7:R555-62. 2005
    ....
  70. pmc Premenopausal plasma 25-hydroxyvitamin D, mammographic density, and risk of breast cancer
    Kimberly A Bertrand
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA
    Breast Cancer Res Treat 149:479-87. 2015
    ..There was evidence that the association between premenopausal 25(OH)D and breast cancer risk varies by mammographic density, with an inverse association apparent only among women with high mammographic density...
  71. pmc Urinary estrogens and estrogen metabolites and mammographic density in premenopausal women
    Kimberly A Bertrand
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res Treat 136:277-87. 2012
    ..If these profiles are associated with breast cancer risk, they may not act through influences on breast density...
  72. ncbi request reprint Endogenous sex hormone levels and mammographic density among postmenopausal women
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:2641-7. 2005
    ..The mechanism by which breast density increases breast cancer risk is unclear although it has been hypothesized that breast density reflects cumulative exposure to estrogens...
  73. pmc Common variants in ZNF365 are associated with both mammographic density and breast cancer risk
    Sara Lindstrom
    Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Nat Genet 43:185-7. 2011
    ..6 × 10(-10)). Common variants in ZNF365 have also recently been associated with susceptibility to breast cancer...
  74. ncbi request reprint Measures of energy balance and mammographic density in the Nurses' Health Study
    Goli Samimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res Treat 109:113-22. 2008
    ..There was no association between recent physical activity and mammographic density. These findings indicate that childhood and adult body fatness and weight change from age 18 are inversely associated with mammographic density...
  75. pmc Mammographic breast density and subsequent risk of breast cancer in postmenopausal women according to tumor characteristics
    Lusine Yaghjyan
    Department of Surgery, Division of Public Health Sciences, Washington University in St Louis School of Medicine, St Louis, MO, USA
    J Natl Cancer Inst 103:1179-89. 2011
    ..We aimed to determine whether the associations between breast density and subsequent breast cancer varied by tumor characteristics...
  76. pmc Genetic variation in the toll-like receptor 4 and prostate cancer incidence and mortality
    Irene M Shui
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Prostate 72:209-16. 2012
    ..Common genetic variants in the Toll-like receptor 4 (TLR4), which is involved in inflammation and immune response pathways, may be important for prostate cancer...
  77. doi request reprint Overdiagnosis of invasive breast cancer due to mammography screening: results from the Norwegian screening program
    Mette Kalager
    Harvard School of Public Health, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Ann Intern Med 156:491-9. 2012
    ....
  78. ncbi request reprint Combined estrogen and testosterone use and risk of breast cancer in postmenopausal women
    Rulla M Tamimi
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 166:1483-9. 2006
    ..Given the increasing trend in the use of hormone therapies containing androgens, we evaluated the relation between the use of estrogen and testosterone therapies and breast cancer...
  79. ncbi request reprint Outcome of patients with ductal carcinoma in situ untreated after diagnostic biopsy: results from the Nurses' Health Study
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Cancer 103:1778-84. 2005
    ..Studies of patients with ductal carcinoma in situ (DCIS) "treated" by diagnostic biopsy alone have been rare, but provide important opportunities to gain insights into the natural history of these lesions...
  80. doi request reprint Birth weight and mammographic density among postmenopausal women in Sweden
    Rulla M Tamimi
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 126:985-91. 2010
    ..These results indicate that adult breast density, a powerful predictor of breast cancer risk, has intrauterine roots, as reflected in birth size...
  81. pmc Migraine and subsequent risk of breast cancer: a prospective cohort study
    Anke C Winter
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Cancer Causes Control 24:81-9. 2013
    ..Further prospective studies are warranted to confirm these results. In addition, studies evaluating migraine characteristics (e.g., migraine subtypes and frequency) are lacking...
  82. pmc The effect of age on delay in diagnosis and stage of breast cancer
    Ann H Partridge
    Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02115, USA
    Oncologist 17:775-82. 2012
    ..We sought to examine the relationship among young age (≤40 years), the likelihood of a delay in diagnosis, and stage...
  83. pmc Single nucleotide polymorphisms and breast cancer: not yet a success story
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Breast Cancer Res 8:108. 2006
    ..Future studies should perhaps also consider alternative designs such as using surrogate (preferably continuous) markers of breast cancer, focusing on high-risk populations, and defining pathologically distinct outcomes...
  84. pmc Body image in recently diagnosed young women with early breast cancer
    Shoshana M Rosenberg
    Harvard School of Public Health, Boston, MA, USA
    Psychooncology 22:1849-55. 2013
    ..To assess body image concerns among young women following a breast cancer diagnosis...
  85. ncbi request reprint Pregnancy estriol, estradiol, progesterone and prolactin in relation to birth weight and other birth size variables (United States)
    Lorelei A Mucci
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Causes Control 14:311-8. 2003
    ....
  86. pmc Average energy intake among pregnant women carrying a boy compared with a girl
    Rulla M Tamimi
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    BMJ 326:1245-6. 2003