Elise B Robinson
Affiliation: Harvard University
- Stability of autistic traits in the general population: further evidence for a continuum of impairmentElise B Robinson
Harvard School of Public Health, Boston, MA, USA
J Am Acad Child Adolesc Psychiatry 50:376-84. 2011..This study investigated the developmental course of autistic traits in a nationally representative sample of subjects 7 to 13 years of age...
- A multivariate twin study of autistic traits in 12-year-olds: testing the fractionable autism triad hypothesisElise B Robinson
Department of Epidemiology, Harvard School of Public Health, 185 Cambridge St, Boston, MA 02114, USA
Behav Genet 42:245-55. 2012..40) and the extremes (0.24-0.67), as well as even lower unique environmental correlations, all suggested considerable fractionation of genetic and environmental influences across autistic trait domains, in line with previous findings...
- Psychosocial predictors of lifestyle management in adults with epilepsyElise Robinson
Department of Society Human Development and Health, Harvard University School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Epilepsy Behav 13:523-8. 2008..Social support was related to self-efficacy. These findings suggest that lifestyle management is influenced by a number of relationships between psychosocial variables, particularly by self-efficacy...
- Brief report: no association between parental age and extreme social-communicative autistic traits in the general populationElise B Robinson
Department of Epidemiology, Harvard School of Public Health, Simches Research Building, Boston, MA 02114, USA
J Autism Dev Disord 41:1733-7. 2011..Neither maternal nor paternal age was associated with extreme scores. These findings suggest that advanced parental age does not confer increased risk for extreme social and communication impairment assessed quantitatively...
- Evidence that autistic traits show the same etiology in the general population and at the quantitative extremes (5%, 2.5%, and 1%)Elise B Robinson
Departments of Epidemiology, and Society, Harvard School of Public Health, Boston, Massachusetts 02114, USA
Arch Gen Psychiatry 68:1113-21. 2011..Genetic factors play an important role in the etiology of both autism spectrum disorders and autistic traits. However, little is known about the etiologic consistency of autistic traits across levels of severity...
- Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general populationElise B Robinson
Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
Nat Genet 48:552-5. 2016..A continuum model should inform the design and interpretation of studies of neuropsychiatric disease biology. ..
- Examining and interpreting the female protective effect against autistic behaviorElise B Robinson
Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA
Proc Natl Acad Sci U S A 110:5258-62. 2013..It provides empirical support for the hypothesis of a female protective effect against autistic behavior and can be used to inform and interpret future gene finding efforts in autism spectrum disorders...
- Association of autistic traits in adulthood with childhood abuse, interpersonal victimization, and posttraumatic stressAndrea L Roberts
Department of Social and Behavioral Sciences, Harvard T H Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA
Child Abuse Negl 45:135-42. 2015..Levels of autistic traits that are highly prevalent in the general population are associated with abuse, trauma and PTSD. ..
- Bipolar polygenic loading and bipolar spectrum features in major depressive disorderAnna Wiste
Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Boston, MA, USA Center for Experimental Drugs and Diagnostics, Department of Psychiatry, Boston, MA, USA
Bipolar Disord 16:608-16. 2014..Family and genetic studies indicate overlapping liability for major depressive disorder and bipolar disorder. The purpose of the present study was to determine whether this shared genetic liability influences clinical presentation...
- A framework for the interpretation of de novo mutation in human diseaseKaitlin E Samocha
1 Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA 2 Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA 3 Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA 4 Program in Genetics and Genomics, Biological and Biomedical Sciences, Harvard Medical School, Boston, Massachusetts, USA
Nat Genet 46:944-50. 2014..We also used our model to identify ∼1,000 genes that are significantly lacking in functional coding variation in non-ASD samples and are enriched for de novo loss-of-function mutations identified in ASD cases. ..
- Bringing a developmental perspective to anxiety geneticsLauren M McGrath
Massachusetts General Hospital, Boston, MA 02114, USA
Dev Psychopathol 24:1179-93. 2012..Expanding the range of phenotypic approaches will be important for advancing studies of the genetic architecture of anxiety disorders...