- A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphateL E Rameh
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA
Nature 390:192-6. 1997..Although PtdIns-5-P was previously thought not to exist in vivo, we find evidence for the presence of this lipid in mammalian fibroblasts, establishing a new pathway for PtdIns-4,5-P2 synthesis...
- Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphateK F Tolias
Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA
J Biol Chem 273:18040-6. 1998..The ability of PIP5Ks to produce multiple signaling molecules indicates that they may participate in a variety of cellular processes...
- Downregulation of JE and KC genes by glucocorticoids does not prevent the G0----G1 transition in BALB/3T3 cellsL E Rameh
Instituto de Quimica, Universidade de Sao Paulo, Brazil
Mol Cell Biol 12:4612-21. 1992..These results suggest that (i) JE and KC are not necessary for the G0----G1----S transition and (ii) c-myc overexpression is likely to be the basis for the potentiating effect of glucocorticoids on serum growth factors...