Ramani Ramchandran

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Cellular actions and signaling by endostatin
    Ramani Ramchandran
    Division of Nephrology, Department of Medicine and Center for Study of the Tumor Microenvironment, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Crit Rev Eukaryot Gene Expr 12:175-91. 2002
  2. pmc Endostatin is a potential inhibitor of Wnt signaling
    Jun Ichi Hanai
    Department of Medicine and Center for Study of the Tumor Microenvironment, Division of Nephrology, Hematology Oncology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    J Cell Biol 158:529-39. 2002
  3. ncbi request reprint A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro
    Guang Hu
    Renal Division, Center for Study of the Tumor Microenvironment and Center for Vascular Biology Research, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Cell Sci 119:4117-26. 2006
  4. ncbi request reprint Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1
    Jun Ichi Hanai
    Divisions of Nephrology and Hematology Oncology, Department of Medicine and Center for Study of the Tumor Microenvironment, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Biol Chem 277:16464-9. 2002
  5. ncbi request reprint Critical roles of CD146 in zebrafish vascular development
    Barden Chan
    Division of Nephrology, Center for Study of the Tumor Microenvironment, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts 02215, USA
    Dev Dyn 232:232-44. 2005
  6. pmc Expression pattern for unc5b, an axon guidance gene in embryonic zebrafish development
    Sukhbir Kaur
    Genome Technology Branch, NHGRI, National Institutes of Health, Bethesda, MD, USA
    Gene Expr 13:321-7. 2007
  7. pmc Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis
    Jack L Arbiser
    Department of Dermatology, Emory University School of Medicine, WMB 5309, 101 Woodruff Circle, Atlanta, GA 30322, USA
    Blood 109:560-5. 2007
  8. ncbi request reprint Robo4 signaling in endothelial cells implies attraction guidance mechanisms
    Sukhbir Kaur
    Laboratory of Pathology, NCI, National Institutes of Health, Rockville, Maryland 20850, USA
    J Biol Chem 281:11347-56. 2006
  9. pmc roundabout4 is essential for angiogenesis in vivo
    Victoria M Bedell
    Laboratory of Pathology, National Cancer Institute, National Institutes of Health, 9610 Medical Center Drive, Suite 320, Rockville, MD 20850, USA
    Proc Natl Acad Sci U S A 102:6373-8. 2005
  10. pmc Syx, a RhoA guanine exchange factor, is essential for angiogenesis in Vivo
    Maija K Garnaas
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Circ Res 103:710-6. 2008

Collaborators

  • Bo Zhang
  • Nathan Bahary
  • Sergei Sokol
  • Seth L Alper
  • J L Arbiser
  • Vikas P Sukhatme
  • Barden Chan
  • D Y Li
  • Arie Horowitz
  • Sukhbir Kaur
  • Jun Ichi Hanai
  • Victoria M Bedell
  • Guang Hu
  • Maija K Garnaas
  • Sang Yeob Yeo
  • Jian Tang
  • S Ananth Karumanchi
  • Jay M Baraban
  • Ganesh V Samant
  • Keguo Li
  • Karen L Moodie
  • Miao liang Liu
  • Ruth Marx
  • Mones S Abu-Abab
  • Mones S Abu-Asab
  • Shobhit Singla
  • Yanfeng Lin
  • Christine Thisse
  • Maria Domenica Castellone
  • Leonard I Zon
  • Bernard Thisse
  • Zhihua Han
  • Jenna Galloway
  • Victoria Bedell
  • Martha Konar
  • J Silvio Gutkind
  • Jeffrey Chung
  • Iain A Drummond
  • Kye Won Park
  • Venkatesha Shivalingappa
  • Jinhua Zhao
  • Pankaj Seth
  • Tomoko Obara
  • Mohan Dhanabal
  • Vivek Jha
  • Richard Pestell
  • Chris Albanese
  • Matthew Waterman
  • Sujata Kale
  • Joachim Gloy

Detail Information

Publications10

  1. pmc Cellular actions and signaling by endostatin
    Ramani Ramchandran
    Division of Nephrology, Department of Medicine and Center for Study of the Tumor Microenvironment, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Crit Rev Eukaryot Gene Expr 12:175-91. 2002
    ..This review summarizes recent advances in endostatin biology and highlights new results on the cellular and subcellular mechanisms of endostatin action...
  2. pmc Endostatin is a potential inhibitor of Wnt signaling
    Jun Ichi Hanai
    Department of Medicine and Center for Study of the Tumor Microenvironment, Division of Nephrology, Hematology Oncology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    J Cell Biol 158:529-39. 2002
    ....
  3. ncbi request reprint A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro
    Guang Hu
    Renal Division, Center for Study of the Tumor Microenvironment and Center for Vascular Biology Research, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Cell Sci 119:4117-26. 2006
    ....
  4. ncbi request reprint Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1
    Jun Ichi Hanai
    Divisions of Nephrology and Hematology Oncology, Department of Medicine and Center for Study of the Tumor Microenvironment, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Biol Chem 277:16464-9. 2002
    ..Collectively, our data pointed to a role for cyclin D1, and in particular, transcription through the LEF1 site as critical for endostatin action in vitro and suggest that beta-catenin is a target for endostatin...
  5. ncbi request reprint Critical roles of CD146 in zebrafish vascular development
    Barden Chan
    Division of Nephrology, Center for Study of the Tumor Microenvironment, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts 02215, USA
    Dev Dyn 232:232-44. 2005
    ..This study provides the first in vivo functional assessment of CD146 in embryonic development by showing that knockdown of CD146 protein expression severely hinders vascular development in zebrafish...
  6. pmc Expression pattern for unc5b, an axon guidance gene in embryonic zebrafish development
    Sukhbir Kaur
    Genome Technology Branch, NHGRI, National Institutes of Health, Bethesda, MD, USA
    Gene Expr 13:321-7. 2007
    ..A similar medial-lateral theme is observed in other neural structures such as the neural tube. Our expression analysis provides a starting point for studying the role of axon guidance genes in embryonic hindbrain patterning...
  7. pmc Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis
    Jack L Arbiser
    Department of Dermatology, Emory University School of Medicine, WMB 5309, 101 Woodruff Circle, Atlanta, GA 30322, USA
    Blood 109:560-5. 2007
    ..Interestingly, solenopsin also inhibited Akt-1 activity in an ATP-competitive manner in vitro without affecting 27 of 28 other protein kinases tested...
  8. ncbi request reprint Robo4 signaling in endothelial cells implies attraction guidance mechanisms
    Sukhbir Kaur
    Laboratory of Pathology, NCI, National Institutes of Health, Rockville, Maryland 20850, USA
    J Biol Chem 281:11347-56. 2006
    ..Taken together, this study suggests that Robo4 mediates attraction-signaling mechanisms through Rho GTPases in vertebrate vascular guidance...
  9. pmc roundabout4 is essential for angiogenesis in vivo
    Victoria M Bedell
    Laboratory of Pathology, National Cancer Institute, National Institutes of Health, 9610 Medical Center Drive, Suite 320, Rockville, MD 20850, USA
    Proc Natl Acad Sci U S A 102:6373-8. 2005
    ..Also, human robo4 gene functionally compensates for loss of robo4 gene function, suggesting evolutionary conservation. This article reports an endothelial-specific function for a robo gene in vertebrates in vivo...
  10. pmc Syx, a RhoA guanine exchange factor, is essential for angiogenesis in Vivo
    Maija K Garnaas
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Circ Res 103:710-6. 2008
    ..These results identify Syx as an essential contributor to angiogenesis in vivo...