Marcello Pagano

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc The effect of spatial aggregation on performance when mapping a risk of disease
    Caroline Jeffery
    Liverpool School of Tropical Medicine, Department of International Public Health, Monitoring and Evaluation Technical assistance and Research group, Liverpool L3 5QA, UK
    Int J Health Geogr 13:9. 2014
  2. pmc Reporting errors in infectious disease outbreaks, with an application to Pandemic Influenza A/H1N1
    Laura F White
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Ave, 3rd Floor, Boston MA 02118 USA
    Epidemiol Perspect Innov 7:12. 2010
  3. pmc Bayes-LQAS: classifying the prevalence of global acute malnutrition
    Casey Olives
    Harvard School of Public Health, Boston, MA, 02115, USA
    Emerg Themes Epidemiol 7:3. 2010
  4. ncbi request reprint Bivariate method for spatio-temporal syndromic surveillance
    Al Ozonoff
    Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    MMWR Suppl 53:59-66. 2004
  5. pmc Cranial ultrasound lesions in the NICU predict cerebral palsy at age 2 years in children born at extremely low gestational age
    Karl C K Kuban
    Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, Massachusetts, USA
    J Child Neurol 24:63-72. 2009
  6. pmc Real time spatial cluster detection using interpoint distances among precise patient locations
    Karen L Olson
    Children s Hospital Informatics Program, Children s Hospital Boston, Boston, Massachusetts, USA
    BMC Med Inform Decis Mak 5:19. 2005
  7. pmc Power to detect spatial disturbances under different levels of geographic aggregation
    Caroline Jeffery
    Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    J Am Med Inform Assoc 16:847-54. 2009
  8. pmc Effective classification of the prevalence of Schistosoma mansoni
    Shira A Mitchell
    Department of Biostatistics, Harvard University, Boston, MA, USA
    Trop Med Int Health 17:1470-7. 2012
  9. pmc Choosing a design to fit the situation: how to improve specificity and positive predictive values using Bayesian lot quality assurance sampling
    Casey Olives
    Department of Biostatistics, University of Washington, Seattle, WA, USA
    Int J Epidemiol 42:346-55. 2013
  10. pmc Effect of spatial resolution on cluster detection: a simulation study
    Al Ozonoff
    Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Int J Health Geogr 6:52. 2007

Research Grants

  1. STATISTICAL MODEL OF THE AIDS EPIDEMIC
    Marcello Pagano; Fiscal Year: 2004
  2. STATISTICAL MODEL OF THE AIDS EPIDEMIC
    Marcello Pagano; Fiscal Year: 2008

Collaborators

Detail Information

Publications39

  1. pmc The effect of spatial aggregation on performance when mapping a risk of disease
    Caroline Jeffery
    Liverpool School of Tropical Medicine, Department of International Public Health, Monitoring and Evaluation Technical assistance and Research group, Liverpool L3 5QA, UK
    Int J Health Geogr 13:9. 2014
    ..Here we consider geographic health data at different levels of spatial resolution, to study the effect of spatial aggregation on disease mapping performance in locating subregions of increased disease risk...
  2. pmc Reporting errors in infectious disease outbreaks, with an application to Pandemic Influenza A/H1N1
    Laura F White
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Ave, 3rd Floor, Boston MA 02118 USA
    Epidemiol Perspect Innov 7:12. 2010
    ..Here we provide insight on the impact that such reporting errors might have on the estimation of these key parameters...
  3. pmc Bayes-LQAS: classifying the prevalence of global acute malnutrition
    Casey Olives
    Harvard School of Public Health, Boston, MA, 02115, USA
    Emerg Themes Epidemiol 7:3. 2010
    ..Results indicate that using a Bayesian approach allows the incorporation of expert information and/or historical data and is thus potentially a valuable tool for making accurate and precise classifications...
  4. ncbi request reprint Bivariate method for spatio-temporal syndromic surveillance
    Al Ozonoff
    Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    MMWR Suppl 53:59-66. 2004
    ..Statistical analysis of syndromic data has typically focused on univariate test statistics for spatial, temporal, or spatio-temporal surveillance. However, this approach does not take full advantage of the information available in the data...
  5. pmc Cranial ultrasound lesions in the NICU predict cerebral palsy at age 2 years in children born at extremely low gestational age
    Karl C K Kuban
    Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, Massachusetts, USA
    J Child Neurol 24:63-72. 2009
    ..Nearly half the cerebral palsy identified at 2 years is not preceded by a neonatal brain ultrasound abnormality...
  6. pmc Real time spatial cluster detection using interpoint distances among precise patient locations
    Karen L Olson
    Children s Hospital Informatics Program, Children s Hospital Boston, Boston, Massachusetts, USA
    BMC Med Inform Decis Mak 5:19. 2005
    ....
  7. pmc Power to detect spatial disturbances under different levels of geographic aggregation
    Caroline Jeffery
    Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    J Am Med Inform Assoc 16:847-54. 2009
    ..This paper investigated the variation in power to detect a change in the spatial distribution in the presence of spatial aggregation...
  8. pmc Effective classification of the prevalence of Schistosoma mansoni
    Shira A Mitchell
    Department of Biostatistics, Harvard University, Boston, MA, USA
    Trop Med Int Health 17:1470-7. 2012
    ..To present an effective classification method based on the prevalence of Schistosoma mansoni in the community...
  9. pmc Choosing a design to fit the situation: how to improve specificity and positive predictive values using Bayesian lot quality assurance sampling
    Casey Olives
    Department of Biostatistics, University of Washington, Seattle, WA, USA
    Int J Epidemiol 42:346-55. 2013
    ..We suggest that poor LQAS performance is due, in part, to variation in the true underlying distribution. However, until now the role of the underlying distribution in expected performance has not been adequately examined...
  10. pmc Effect of spatial resolution on cluster detection: a simulation study
    Al Ozonoff
    Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Int J Health Geogr 6:52. 2007
    ..Aggregation of spatial data is intended to protect privacy, but some effects of aggregation on spatial methods have not yet been quantified...
  11. pmc Health indicators: eliminating bias from convenience sampling estimators
    Bethany L Hedt
    Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA
    Stat Med 30:560-8. 2011
    ..This allows us to not only take advantage of powerful inferential tools, but also provides more accurate information than that available from just using data from the random sample alone...
  12. ncbi request reprint Systemic hypotension and white-matter damage in preterm infants
    Olaf Dammann
    Children s Hospital, Boston, MA 02115, USA
    Dev Med Child Neurol 44:82-90. 2002
    ..In sum, these results do not support the hypothesis that systemic hypotension contributes to echolucency among preterm infants...
  13. ncbi request reprint Variability in surgical caseload and access to intensive care services
    Michael L McManus
    Department of Anesthesia and the Multidisciplinary Intensive Care Unit, Children s Hospital Boston and Harvard Medical School, Massachusetts 02115, USA
    Anesthesiology 98:1491-6. 2003
    ..Intensive care units may frequently present bottlenecks to patient flow, and saturation of these services limits a hospital's responsiveness to new emergencies...
  14. pmc Estimating the magnitude and direction of bias in tuberculosis drug resistance surveys conducted only in the public sector: a simulation study
    Ted Cohen
    Division of Global Health Equity, Brigham and Women s Hospital, 641 Huntington Avenue, Boston 02115, USA
    BMC Public Health 10:355. 2010
    ..However, in locations where a substantial fraction of TB cases seek care with private providers, these surveys may not accurately measure resistance in the entire population...
  15. ncbi request reprint Using treatment failure under effective directly observed short-course chemotherapy programs to identify patients with multidrug-resistant tuberculosis
    M C Becerra
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Int J Tuberc Lung Dis 4:108-14. 2000
    ..Public ambulatory care centers in three districts of northern metropolitan Lima, Peru...
  16. ncbi request reprint Do clinical markers of barotrauma and oxygen toxicity explain interhospital variation in rates of chronic lung disease? The Neonatology Committee for the Developmental Network
    L J Van Marter
    Children s Hospital, Boston, Massachusetts 02115, USA
    Pediatrics 105:1194-201. 2000
    ..To explore the hypothesis that variation in respiratory management among newborn intensive care units (NICUs) explains differences in chronic lung disease (CLD) rates...
  17. pmc The effect of clustering on lot quality assurance sampling: a probabilistic model to calculate sample sizes for quality assessments
    Bethany L Hedt-Gauthier
    Department of Global Health and Social Medicine, Harvard Medical School, Boston, USA
    Emerg Themes Epidemiol 10:11. 2013
    ..In this paper, we develop a general framework for designing the cluster(C)-LQAS system and illustrate the method with the design of data quality assessments for the community health worker program in Rwanda...
  18. pmc Pooled testing for effective estimation of the prevalence of Schistosoma mansoni
    Shira Mitchell
    Harvard University Biostatistics, Boston, MA, USA
    Am J Trop Med Hyg 87:850-61. 2012
    ..Thus, we can use half as many slides while maintaining accuracy. Such savings might encourage more frequent measurements in regions where schistosomiasis is a serious but neglected problem...
  19. pmc Improving the power of chronic disease surveillance by incorporating residential history
    Justin Manjourides
    Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, U S A
    Stat Med 30:2222-33. 2011
    ....
  20. pmc Determining the dynamics of influenza transmission by age
    Laura F White
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Ave, Boston, MA 02118, USA
    Emerg Themes Epidemiol 11:4. 2014
    ..We illustrate this method using data from the 2009 H1N1 Influenza pandemic in Gauteng Province, South Africa...
  21. doi request reprint Comparing two survey methods of measuring health-related indicators: Lot Quality Assurance Sampling and Demographic Health Surveys
    Sarah C Anoke
    Department of Biostatistics, Harvard T H Chan School of Public Health, Boston, MA, USA
    Trop Med Int Health 20:1756-70. 2015
    ..We report on both methods when utilised in comparable situations...
  22. pmc A novel approach to evaluating the iron and folate status of women of reproductive age in Uzbekistan after 3 years of flour fortification with micronutrients
    Lauren Hund
    Harvard School of Public Health, Boston, Massachusetts, United States of America University of New Mexico, Albuquerque, United States of America
    PLoS ONE 8:e79726. 2013
    ..Fortification of wheat flour was identified as an appropriate intervention to address anemia due to the ubiquitous consumption of wheat flour. A National Flour Fortification Program (NFFP) was implemented in 2005...
  23. pmc Multiple category-lot quality assurance sampling: a new classification system with application to schistosomiasis control
    Casey Olives
    Department of Biostatistics, University of Washington, Seattle, Washington, USA
    PLoS Negl Trop Dis 6:e1806. 2012
    ..We explore the analytical properties of MC-LQAS, and validate its use for the classification of S. mansoni prevalence in multiple settings in East Africa...
  24. pmc Estimation of the reproductive number and the serial interval in early phase of the 2009 influenza A/H1N1 pandemic in the USA
    Laura Forsberg White
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    Influenza Other Respir Viruses 3:267-76. 2009
    ..Appropriate public health responses to this pandemic depend in part on early estimates of key epidemiological parameters of the virus in defined populations...
  25. ncbi request reprint Combining cross-sectional and prospective data methods to improve transition parameter estimation for characterizing the accumulation of HIV-1 drug resistance mutations
    Brian Healy
    Department of Biostatistics, Harvard University, 655 Huntington Avenue, Boston, Massachusetts 02115, USA
    Biometrics 63:742-50. 2007
    ..Combining the two sources of information allows detection of differences between rates of transition that are not detectable using prospective data alone...
  26. pmc Effects of latitude and longitude on the population structure of Culex pipiens s.l., vectors of West Nile virus in North America
    Frances Edillo
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Am J Trop Med Hyg 81:842-8. 2009
    ..Northern Cx. p. pipiens may have undergone additional generations before diapause is triggered, magnifying population size when WNV amplification is peaking...
  27. pmc Transmissibility of the influenza virus in the 1918 pandemic
    Laura Forsberg White
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA
    PLoS ONE 3:e1498. 2008
    ..With a heightened increase in concern for an influenza pandemic we sought to better understand the 1918 Influenza pandemic, the most devastating epidemic of the previous century...
  28. ncbi request reprint The interpoint distance distribution as a descriptor of point patterns, with an application to spatial disease clustering
    Marco Bonetti
    Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA
    Stat Med 24:753-73. 2005
    ....
  29. pmc Improving data quality and supervision of antiretroviral therapy sites in Malawi: an application of Lot Quality Assurance Sampling
    Bethany L Hedt-Gauthier
    Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA
    BMC Health Serv Res 12:196. 2012
    ....
  30. pmc Estimating the reproductive number in the presence of spatial heterogeneity of transmission patterns
    Laura F White
    Department of Biostatistics, Boston University School of Public Health, 801 Massachussetts Ave, Boston, MA 02118, USA
    Int J Health Geogr 12:35. 2013
    ..For control measures to be more effective, a measure of the heterogeneity of the parameters is desirable...
  31. pmc An algorithm for identifying and classifying cerebral palsy in young children
    Karl C K Kuban
    Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, MA, USA
    J Pediatr 153:466-72. 2008
    ....
  32. pmc Using temporal context to improve biosurveillance
    Ben Y Reis
    Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 100:1961-5. 2003
    ..Furthermore, for increased robustness and performance, hybrid systems should be developed to capitalize on the complementary strengths of different types of temporal filters...
  33. pmc An assessment of Lot Quality Assurance Sampling to evaluate malaria outcome indicators: extending malaria indicator surveys
    Caitlin Biedron
    Department of Global Health and Population, Harvard School of Public Health, Boston, MA, USA
    Int J Epidemiol 39:72-9. 2010
    ..Lot Quality Assurance Sampling (LQAS) has played a valuable role for local-level programme M&E. If incorporated into these larger surveys, it would provide a comprehensive M&E plan at little, if any, extra cost...
  34. ncbi request reprint Risk of cranial ultrasound abnormalities in very-low-birth-weight infants conceived with assisted reproductive techniques
    Jane E Stewart
    Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    J Perinatol 22:37-45. 2002
    ....
  35. ncbi request reprint Chorioamnionitis, mechanical ventilation, and postnatal sepsis as modulators of chronic lung disease in preterm infants
    Linda J Van Marter
    Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Pediatr 140:171-6. 2002
    ..This case-control study of chronic lung disease (CLD) evaluated the hypothesis that chorioamnionitis promotes CLD and interacts with other risk factors for CLD, including mechanical ventilation and postnatal infection...
  36. ncbi request reprint Antenatal glucocorticoid treatment does not reduce chronic lung disease among surviving preterm infants
    L J Van Marter
    Children's Hospital, Boston, Massachusetts 02115, USA
    J Pediatr 138:198-204. 2001
    ....
  37. pmc A likelihood-based method for real-time estimation of the serial interval and reproductive number of an epidemic
    L Forsberg White
    Department of Biostatistics, Boston University School of Public Health, 715 Albany St, Boston, MA 02118, USA
    Stat Med 27:2999-3016. 2008
    ..We provide simulation results that illustrate the efficacy of the method for estimating R(0) and the serial interval in real time. Finally, we implement our proposed method with data from three infectious disease outbreaks...
  38. pmc Use of the pediatric symptom checklist in strategies to improve preventive behavioral health care
    M Navon
    Neighborhood Health Plan, Boston, MA, USA
    Psychiatr Serv 52:800-4. 2001
    ..The purpose of this study was to examine the utility of the Pediatric Symptom Checklist (PSC) in identifying youth at risk of behavioral health problems and to develop strategies to meet their mental health needs...
  39. pmc Neonatal cranial ultrasound lesions and developmental delays at 2 years of age among extremely low gestational age children
    T MICHAEL O'SHEA
    Wake Forest University Health Sciences, Department of Pediatrics, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Pediatrics 122:e662-9. 2008
    ..Studies of the relationship between ultrasound images from preterm newborns and developmental delay most often are based on small samples defined by birth weight and exclude infants not testable with standardized assessments...

Research Grants2

  1. STATISTICAL MODEL OF THE AIDS EPIDEMIC
    Marcello Pagano; Fiscal Year: 2004
    ..This is challenging because the patterns of viral trajectory vary greatly across subjects, measurements are often censored due to assay limitations, and data are often missing. ..
  2. STATISTICAL MODEL OF THE AIDS EPIDEMIC
    Marcello Pagano; Fiscal Year: 2008
    ..These aims, if fulfilled, should help in the public health effort to control the spread of the epidemic and to better treat those already infected. ..