Lorelei Mucci

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Effects of G/A polymorphism, rs266882, in the androgen response element 1 of the PSA gene on prostate cancer risk, survival and circulating PSA levels
    C Jesser
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Br J Cancer 99:1743-7. 2008
  2. pmc Dietary lycopene, angiogenesis, and prostate cancer: a prospective study in the prostate-specific antigen era
    Ke Zu
    Affiliations of authors Department of Nutrition KZ, MJS, Eg, Department of Epidemiology LM, MJS, Eg, and Department of Biostatistics BAR, Harvard School of Public Health, Boston, MA Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA LM, Bar, MJS, EG Department of Internal Medicine, The Ohio State University, Columbus, OH SKC Department of Pathology, Dana Farber Cancer Institute, Boston, MA ML
    J Natl Cancer Inst 106:djt430. 2014
  3. pmc Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of beta-catenin in prostate cancer
    Michelangelo Fiorentino
    Department of Medical Oncology, Center for Molecular Oncologic Pathology, Dana Farber Cancer Institute, Brigham and Women s Hospital, Boston, MA, USA
    Lab Invest 88:1340-8. 2008
  4. pmc Immunohistochemical expression of BRCA1 and lethal prostate cancer
    Michelangelo Fiorentino
    Department of Pathology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 70:3136-9. 2010
  5. pmc Evaluation of 8q24 and 17q risk loci and prostate cancer mortality
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Harvard University, Cambridge, Massachusetts, USA
    Clin Cancer Res 15:3223-30. 2009
  6. pmc ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer
    Changmeng Cai
    Hematology Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    J Clin Invest 123:1109-22. 2013
  7. pmc Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis
    Jing Ma
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Lancet Oncol 9:1039-47. 2008
  8. pmc SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
    Zhihu Ding
    Belfer Institute for Applied Cancer Science, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Nature 470:269-73. 2011
  9. ncbi request reprint Diagnostic tests in urology: magnetic resonance imaging (MRI) for the staging of prostate cancer
    Mark A Preston
    Department of Urology, Massachusetts General Hospital Harvard School of Public Health, Boston, MA, USA
    BJU Int 111:514-7. 2013
  10. pmc Shiftwork and prostate-specific antigen in the National Health and Nutrition Examination Survey
    Erin E Flynn-Evans
    Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Natl Cancer Inst 105:1292-7. 2013

Collaborators

Detail Information

Publications13

  1. pmc Effects of G/A polymorphism, rs266882, in the androgen response element 1 of the PSA gene on prostate cancer risk, survival and circulating PSA levels
    C Jesser
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Br J Cancer 99:1743-7. 2008
    ..Meta-analysis of 12 studies of rs266882 and overall prostate cancer risk was null...
  2. pmc Dietary lycopene, angiogenesis, and prostate cancer: a prospective study in the prostate-specific antigen era
    Ke Zu
    Affiliations of authors Department of Nutrition KZ, MJS, Eg, Department of Epidemiology LM, MJS, Eg, and Department of Biostatistics BAR, Harvard School of Public Health, Boston, MA Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA LM, Bar, MJS, EG Department of Internal Medicine, The Ohio State University, Columbus, OH SKC Department of Pathology, Dana Farber Cancer Institute, Boston, MA ML
    J Natl Cancer Inst 106:djt430. 2014
    ....
  3. pmc Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of beta-catenin in prostate cancer
    Michelangelo Fiorentino
    Department of Medical Oncology, Center for Molecular Oncologic Pathology, Dana Farber Cancer Institute, Brigham and Women s Hospital, Boston, MA, USA
    Lab Invest 88:1340-8. 2008
    ..001, Spearman's rho=0.33). We propose that cytoplasmic stabilization of beta-catenin through palmitoylation of Wnt-1 and subsequent activation of the pathway is a potential mechanism of FASN oncogenicity in prostate cancer...
  4. pmc Immunohistochemical expression of BRCA1 and lethal prostate cancer
    Michelangelo Fiorentino
    Department of Pathology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 70:3136-9. 2010
    ..6; 95% confidence interval, 2.4-8.7). These findings strengthen the hypothesis that BRCA1 plays a role in cell cycle control and show that BRCA1 is a marker of clinical prostate cancer prognosis. Cancer Res; 70(8); 3136-9. (c)2010 AACR...
  5. pmc Evaluation of 8q24 and 17q risk loci and prostate cancer mortality
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Harvard University, Cambridge, Massachusetts, USA
    Clin Cancer Res 15:3223-30. 2009
    ..We investigated whether the 8q24 and 17q risk variants are associated with clinical variables as well as prostate cancer mortality...
  6. pmc ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer
    Changmeng Cai
    Hematology Oncology Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    J Clin Invest 123:1109-22. 2013
    ..Together, these results demonstrate that ERG redirects AR to a set of genes including SOX9 that are not normally androgen stimulated, and identify SOX9 as a critical downstream effector of ERG in TMPRSS2:ERG fusion-positive PCa...
  7. pmc Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis
    Jing Ma
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Lancet Oncol 9:1039-47. 2008
    ..We assessed the effect of prediagnostic BMI and plasma C-peptide concentration (reflecting insulin secretion) on prostate cancer-specific mortality after diagnosis...
  8. pmc SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
    Zhihu Ding
    Belfer Institute for Applied Cancer Science, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Nature 470:269-73. 2011
    ..This model-informed progression analysis, together with genetic, functional and translational studies, establishes SMAD4 as a key regulator of PCA progression in mice and humans...
  9. ncbi request reprint Diagnostic tests in urology: magnetic resonance imaging (MRI) for the staging of prostate cancer
    Mark A Preston
    Department of Urology, Massachusetts General Hospital Harvard School of Public Health, Boston, MA, USA
    BJU Int 111:514-7. 2013
    ..This evidence-based medicine article addresses the clinical utility of prostate MRI for preoperative staging. Based on a common patient scenario, a guide to calculating the probability of extraprostatic extension is provided...
  10. pmc Shiftwork and prostate-specific antigen in the National Health and Nutrition Examination Survey
    Erin E Flynn-Evans
    Division of Sleep Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Natl Cancer Inst 105:1292-7. 2013
    ..Our aim was to investigate the relationship between shiftwork and prostate-specific antigen (PSA) test obtained as part of the National Health and Nutrition Examination Survey (NHANES) study...
  11. ncbi request reprint Decreased alpha-methylacyl CoA racemase expression in localized prostate cancer is associated with an increased rate of biochemical recurrence and cancer-specific death
    Mark A Rubin
    Department of Pathology Amory 3 195, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:1424-32. 2005
    ..This is the first study to show that AMACR expression is significantly associated with prostate cancer progression and suggests that not all surrogate end points may be optimal to define biomarkers of aggressive prostate cancer...
  12. pmc Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer
    Toshiro Migita
    Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    J Natl Cancer Inst 101:519-32. 2009
    ..Overexpression of the fatty acid synthase (FASN) gene has been implicated in prostate carcinogenesis. We sought to directly assess the oncogenic potential of FASN...
  13. pmc Evaluation of the 8q24 prostate cancer risk locus and MYC expression
    Mark M Pomerantz
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Cancer Res 69:5568-74. 2009
    ..These data will help to direct the future study of this risk locus...