Rebekah Mannix

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Traumatic brain injury, microglia, and Beta amyloid
    Rebekah C Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, MA 02124, USA
    Int J Alzheimers Dis 2012:608732. 2012
  2. doi request reprint Isolated skull fractures: trends in management in US pediatric emergency departments
    Rebekah Mannix
    Division of Emergency Medicine, Department of Medicine, Boston Children s Hospital, and Harvard Medical School, Harvard University, Boston, MA Electronic address
    Ann Emerg Med 62:327-31. 2013
  3. doi request reprint The epidemiology of outpatient visits for minor head injury: 2005 to 2009
    Rebekah Mannix
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Massachusetts, USA
    Neurosurgery 73:129-34; discussion 134. 2013
  4. doi request reprint Beneficial effect of amyloid beta after controlled cortical impact
    Rebekah C Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Brain Inj 27:743-8. 2013
  5. pmc Computed tomography for minor head injury: variation and trends in major United States pediatric emergency departments
    Rebekah Mannix
    Department of Medicine, Children s Hospital Boston, Boston, MA, USA
    J Pediatr 160:136-9.e1. 2012
  6. doi request reprint Booster seat laws and fatalities in children 4 to 7 years of age
    Rebekah Mannix
    Divisions of aEmergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Pediatrics 130:996-1002. 2012
  7. doi request reprint Insurance status and the care of children in the emergency department
    Rebekah Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Boston, MA, USA
    J Pediatr 161:536-541.e3. 2012
  8. doi request reprint Insurance status and the care of adult patients 19 to 64 years of age visiting the emergency department
    Rebekah Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Boston, MA, USA
    Acad Emerg Med 19:808-15. 2012
  9. ncbi request reprint Status asthmaticus in children
    Rebekah Mannix
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Curr Opin Pediatr 19:281-7. 2007
  10. pmc Age-dependent effect of apolipoprotein E4 on functional outcome after controlled cortical impact in mice
    Rebekah C Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Cereb Blood Flow Metab 31:351-61. 2011

Collaborators

Detail Information

Publications44

  1. pmc Traumatic brain injury, microglia, and Beta amyloid
    Rebekah C Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, MA 02124, USA
    Int J Alzheimers Dis 2012:608732. 2012
    ..Data from both AD and TBI studies suggest that microglia play a central role in Aβ accumulation after TBI. This paper focuses on the current research on the role of microglia response to Aβ after TBI...
  2. doi request reprint Isolated skull fractures: trends in management in US pediatric emergency departments
    Rebekah Mannix
    Division of Emergency Medicine, Department of Medicine, Boston Children s Hospital, and Harvard Medical School, Harvard University, Boston, MA Electronic address
    Ann Emerg Med 62:327-31. 2013
    ..We seek to evaluate current practice for children presenting to the emergency department (ED) for isolated skull fractures in US children's hospitals...
  3. doi request reprint The epidemiology of outpatient visits for minor head injury: 2005 to 2009
    Rebekah Mannix
    Division of Emergency Medicine, Children s Hospital Boston, Boston, Massachusetts, USA
    Neurosurgery 73:129-34; discussion 134. 2013
    ..The Centers for Disease Control and Prevention have called for studies detailing the prevalence and burden of mild traumatic brain injury (mTBI) in the outpatient clinical setting...
  4. doi request reprint Beneficial effect of amyloid beta after controlled cortical impact
    Rebekah C Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    Brain Inj 27:743-8. 2013
    ..This study investigated whether reconstitution of amyloid-beta (Aβ) after CCI in Bace1(-/-) animals would reverse the detrimental effect of Bace1 deletion...
  5. pmc Computed tomography for minor head injury: variation and trends in major United States pediatric emergency departments
    Rebekah Mannix
    Department of Medicine, Children s Hospital Boston, Boston, MA, USA
    J Pediatr 160:136-9.e1. 2012
    ..To investigate the variation and trends in neuroimaging in children examined for minor head injury at major US pediatric emergency departments...
  6. doi request reprint Booster seat laws and fatalities in children 4 to 7 years of age
    Rebekah Mannix
    Divisions of aEmergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Pediatrics 130:996-1002. 2012
    ..To determine whether state booster seat laws were associated with decreased fatality rates in children 4 to 7 years of age in the United States...
  7. doi request reprint Insurance status and the care of children in the emergency department
    Rebekah Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Boston, MA, USA
    J Pediatr 161:536-541.e3. 2012
    ..To determine whether insurance status is associated with the use of diagnostic testing or intervention in the emergency department (ED) care of children...
  8. doi request reprint Insurance status and the care of adult patients 19 to 64 years of age visiting the emergency department
    Rebekah Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Boston, MA, USA
    Acad Emerg Med 19:808-15. 2012
    ..The objective was to determine whether insurance status is associated with the care of patients presenting to the emergency department (ED)...
  9. ncbi request reprint Status asthmaticus in children
    Rebekah Mannix
    Division of Emergency Medicine, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
    Curr Opin Pediatr 19:281-7. 2007
    ..The prevalence of severe asthma in children has risen in the past few decades. The present review explores our current understanding of epidemiology, pathophysiology and treatment of status asthmaticus in children...
  10. pmc Age-dependent effect of apolipoprotein E4 on functional outcome after controlled cortical impact in mice
    Rebekah C Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Cereb Blood Flow Metab 31:351-61. 2011
    ..The data suggest age-dependent effects of APOE4 on cognitive outcome after TBI, and that therapies targeting APOE4 may be more effective in adults versus children with TBI...
  11. pmc Factors associated with the use of cervical spine computed tomography imaging in pediatric trauma patients
    Rebekah Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, MA, USA
    Acad Emerg Med 18:905-11. 2011
    ....
  12. pmc Neuroimaging for pediatric head trauma: do patient and hospital characteristics influence who gets imaged?
    Rebekah Mannix
    Department of Medicine, Children s Hospital Boston, MA, USA
    Acad Emerg Med 17:694-700. 2010
    ..The objective was to identify patient, provider, and hospital characteristics associated with the use of neuroimaging in the evaluation of head trauma in children...
  13. pmc Detrimental effect of genetic inhibition of B-site APP-cleaving enzyme 1 on functional outcome after controlled cortical impact in young adult mice
    Rebekah C Mannix
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurotrauma 28:1855-61. 2011
    ..The data suggest that therapies targeting Bace1 may need to be tailored according to age and injury severity, as their use may exacerbate functional deficits after TBI in younger or less severely injured patients...
  14. ncbi request reprint Acute pediatric rhabdomyolysis: causes and rates of renal failure
    Rebekah Mannix
    Division of Emergency Medicine, Children s Hospital, 300 Longwood Ave, Boston, MA 02115, USA
    Pediatrics 118:2119-25. 2006
    ....
  15. doi request reprint Clinical correlates in an experimental model of repetitive mild brain injury
    Rebekah Mannix
    Division of Emergency Medicine, Boston Children s Hospital, Boston, MA Harvard Medical School, Boston, MA
    Ann Neurol 74:65-75. 2013
    ..Here, we use an experimental model of rmTBI to address these clinical controversies...
  16. ncbi request reprint Increasing recovery time between injuries improves cognitive outcome after repetitive mild concussive brain injuries in mice
    William P Meehan
    Sports Concussion Clinic, Division of Sports Medicine, Department of Orthopedics and Brain Injury Center, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    Neurosurgery 71:885-91. 2012
    ..Although previous evidence suggests that the cognitive effects of concussions are cumulative, the effect of time interval between repeat concussions is largely unknown...
  17. doi request reprint Outcomes of pediatric patients with persistent midline cervical spine tenderness and negative imaging result after trauma
    Kate Dorney
    From the Departments of Emergency Medicine K D, A K, M H, K H, R M, Neurosurgery M P, Surgery D P M, and Orthopedics M G, Boston Children s Hospital, Boston and The Micheli Center for Sports Injury Prevention WPM, Waltham, Massachusetts
    J Trauma Acute Care Surg 79:822-7. 2015
    ....
  18. ncbi request reprint Consistency of Self-Reported Concussion History in Adolescent Athletes
    Magdalena Wojtowicz
    1 Department of Psychiatry, Harvard Medical School, Boston, Massachusetts
    J Neurotrauma . 2016
    ..Overall, these findings suggest that student athletes are quite consistent when reporting their concussion history when surveyed twice during high school...
  19. doi request reprint Firearm Ownership and Violent Crime in the U.S.: An Ecologic Study
    Michael C Monuteaux
    Boston Children s Hospital, Boston, Massachusetts Electronic address
    Am J Prev Med 49:207-14. 2015
    ..The purpose of this study is to test the association between state-level firearm ownership and violent crime...
  20. pmc Duration and course of post-concussive symptoms
    Matthew A Eisenberg
    Division of Emergency Medicine, Boston Children s Hospital, Harvard Medical School, Boston, Massachusetts
    Pediatrics 133:999-1006. 2014
    ..To examine the incidence, duration, and clinical course of individual post-concussive symptoms in patients presenting to a pediatric emergency department (ED) with a concussion...
  21. pmc A substantial proportion of life-threatening injuries are sport-related
    William P Meehan
    The Micheli Center for Sports Injury Prevention, Waltham, MA, USA
    Pediatr Emerg Care 29:624-7. 2013
    ..This study aimed to assess the proportion of all life-threatening injuries that are sport-related...
  22. doi request reprint Pediatric traumatic brain injury and radiation risks: a clinical decision analysis
    Kara E Hennelly
    Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    J Pediatr 162:392-7. 2013
    ....
  23. doi request reprint Predictors and Outcomes of Pediatric Firearm Injuries Treated in the Emergency Department: Differences by Mechanism of Intent
    Michael C Monuteaux
    Boston Children s Hospital, Boston, MA
    Acad Emerg Med 23:790-5. 2016
    ..Our objective was to investigate differences in predictors and clinical outcomes between self-inflicted, violent, and unintentional pediatric firearm injuries for patients who present to pediatric emergency departments (EDs)...
  24. doi request reprint Variation and Trends in Charges for Pediatric Care in Massachusetts Emergency Departments, 2000-2011
    Michael C Monuteaux
    Division of Emergency Medicine, Boston Children s Hospital, Boston, MA
    Acad Emerg Med 22:1164-71. 2015
    ..Our objective was to examine trends and variability in ED charges for pediatric patients across Massachusetts...
  25. pmc Early symptom burden predicts recovery after sport-related concussion
    William P Meehan
    From The Micheli Center for Sports Injury Prevention W P M, Waltham and the Sports Concussion Clinic, Division of Sports Medicine W P M, C J S, Division of Emergency Medicine W P M, R M, M C M, R G B, and Brain Injury Center W P M, R M, Boston Children s Hospital, MA
    Neurology 83:2204-10. 2014
    ..To identify independent predictors of and use recursive partitioning to develop a multivariate regression tree predicting symptom duration greater than 28 days after a sport-related concussion...
  26. doi request reprint Firearm legislation and firearm-related fatalities in the United States
    Eric W Fleegler
    Division of Emergency Medicine, Boston Children s Hospital, 300 Longwood Ave, Boston, MA 02115, USA
    JAMA Intern Med 173:732-40. 2013
    ..Over 30,000 people die annually in the United States from injuries caused by firearms. Although most firearm laws are enacted by states, whether the laws are associated with rates of firearm deaths is uncertain...
  27. pmc Pediatric concussions in United States emergency departments in the years 2002 to 2006
    William P Meehan
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Boston, MA, USA
    J Pediatr 157:889-93. 2010
    ..To estimate the incidence and demographics of concussions in children coming to emergency departments (EDs) in the United States and describe the rates of neuroimaging and follow-up instructions in these patients...
  28. pmc Initial symptom burden predicts duration of symptoms after concussion
    William P Meehan
    The Micheli Center for Sports Injury Prevention, United States Sports Concussion Clinic, Division of Sports Medicine, Boston Children s Hospital, United States Brain Injury Center, Boston Children s Hospital, United States Division of Emergency Medicine, Boston Children s Hospital, United States Electronic address
    J Sci Med Sport 19:722-5. 2016
    ..To determine which variables predict prolonged (>28 days) duration of symptoms after a concussion...
  29. doi request reprint Emergency Department Management of Febrile Respiratory Illness in Children
    Sonal Shah
    From the Division of Emergency Medicine, Department of Medicine, Children s Hospital, Harvard Medical School, Boston, MA
    Pediatr Emerg Care 32:429-34. 2016
    ..There are limited data regarding testing and treatment patterns for children presenting to the emergency department (ED) with a febrile respiratory illness...
  30. doi request reprint Sports-related concussions - media, science and policy
    Rebekah Mannix
    Division of Emergency Medicine, 300 Longwood Avenue, Boston, Massachusetts 02115, USA
    Nat Rev Neurol 12:486-90. 2016
    ..In this article, we discuss current knowledge on sports-related concussion, its neurological consequences, and implications for regulation of the practice of collision sports. ..
  31. pmc Adolescent Mice Demonstrate a Distinct Pattern of Injury after Repetitive Mild Traumatic Brain Injury
    Rebekah Mannix
    1 Division of Emergency Medicine, Boston Children s Hospital, Boston, Massachusetts
    J Neurotrauma . 2016
    ..The data suggest that injured adolescent mice may show a distinct pattern of functional deficits after injury that warrants further mechanistic studies...
  32. pmc Microstructural and microglial changes after repetitive mild traumatic brain injury in mice
    Shenandoah Robinson
    Departments of Neurosurgery and Neurology, Boston Children s Hospital, Kirby Center for Neurobiology, Harvard Medical School, Boston, Massachusetts
    J Neurosci Res . 2016
    ..These findings suggest new diagnostic techniques that can be used as biomarkers to guide the use of future protective or reparative interventions. © 2016 Wiley Periodicals, Inc...
  33. doi request reprint Clinical Traumatic Brain Injury in the Preclinical Setting
    Justin Berkner
    Division of Emergency Medicine, Boston Children s Hospital, 300 Longwood Avenue, Boston, MA, 02115, USA
    Methods Mol Biol 1462:11-28. 2016
    ..Each of these models replicates particular critical aspects of clinical TBI. Prior to selecting a preclinical TBI model, it is important to address what aspect of human TBI is being sought to evaluate. ..
  34. doi request reprint Trends in pediatric visits to the emergency department for psychiatric illnesses
    Zachary E Pittsenbarger
    From the Division of Emergency Medicine, Department of Medicine, Boston Children s Hospital, Boston, MA
    Acad Emerg Med 21:25-30. 2014
    ..The study aim was to evaluate the trends in ED psychiatric visits for children between 2001 and 2010 with comparison by sociodemographic characteristics...
  35. doi request reprint Epidemiology, trends, assessment and management of sport-related concussion in United States high schools
    Rejean M Guerriero
    Brain Injury Center, Boston Children s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Curr Opin Pediatr 24:696-701. 2012
    ....
  36. doi request reprint Acute pediatric monoarticular arthritis: distinguishing lyme arthritis from other etiologies
    Amy Thompson
    Children s Hospital Boston, Division of Emergency Medicine, 300 Longwood Ave, Boston, MA 02115, USA
    Pediatrics 123:959-65. 2009
    ..Identify clinical predictors of Lyme arthritis among patients with acute monoarticular arthritis...
  37. ncbi request reprint Carbon Monoxide Exposure in Youth Ice Hockey
    Theodore Macnow
    UMass Memorial Children s Medical Center, Worcester, Massachusetts University of Massachusetts Medical School, Worcester, Massachusetts Division of Emergency Medicine, Boston Children s Hospital, Boston, Massachusetts Harvard Medical School, Boston, Massachusetts Brain Injury Center, Boston Children s Hospital, Boston, Massachusetts The Micheli Center for Sports Injury Prevention, Waltham, Massachusetts Sports Concussion Clinic, Boston Children s Hospital, Boston, Massachusetts and Division of Sports Medicine, Boston Children s Hospital, Boston, Massachusetts
    Clin J Sport Med . 2016
    ....
  38. doi request reprint Factors Associated With Concussion-like Symptom Reporting in High School Athletes
    Grant L Iverson
    Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, Massachusetts2Spaulding Rehabilitation Hospital, Boston, Massachusetts3MassGeneral Hospital for Children Sports Concussion Program, Boston4Red Sox Foundation and Massachus
    JAMA Pediatr 169:1132-40. 2015
    ..Safely returning athletes to sport after concussion relies on accurately determining when their symptoms resolve...
  39. pmc Chronic traumatic encephalopathy and athletes
    William Meehan
    From the Micheli Center for Sports Injury Prevention W M, Waltham the Brain Injury Center W M, R M, Sports Concussion Clinic, Division of Sports Medicine W M, and Division of Emergency Medicine W M, R M, Boston Children s Hospital the Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital R Z, Massachusetts General Hospital, Brigham and Women s Hospital and the Berenson Allen Center and Division of Interventional Cognitive Neurosciences, Department of Neurology A P L, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA
    Neurology 85:1504-11. 2015
    ..This article discusses the current evidence and the associated limitations. ..
  40. doi request reprint Restraint use in motor vehicle crash fatalities in children 0 year to 9 years old
    Lois K Lee
    From the Division of Emergency Medicine, Boston Children s Hospital, Boston, Massachusetts
    J Trauma Acute Care Surg 79:S55-60. 2015
    ..The objective of this study was to describe factors associated with restraint use in fatal MVC in children 0 year to 9 years old...
  41. doi request reprint Pediatric cervical spine injury evaluation after blunt trauma: a clinical decision analysis
    Megan Hannon
    Division of Emergency Medicine, Boston Children s Hospital, Boston, MA Electronic address
    Ann Emerg Med 65:239-47. 2015
    ..We determine the optimal initial evaluation strategy for cervical spine injury in pediatric blunt trauma...
  42. pmc Complex pattern of interaction between in utero hypoxia-ischemia and intra-amniotic inflammation disrupts brain development and motor function
    Lauren L Jantzie
    Departments of Neurology and Neurosurgery, F, M, Kirby Center for Neurobiology, Boston Children s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    J Neuroinflammation 11:131. 2014
    ....
  43. doi request reprint Serum biomarkers predict acute symptom burden in children after concussion: a preliminary study
    Rebekah Mannix
    1 Division of Emergency Medicine, Boston Children s Hospital, Boston, Massachusetts
    J Neurotrauma 31:1072-5. 2014
    ..These preliminary data suggest that GFAP may offer an objective measure of injury and recovery after pediatric concussion, potentially offering clinicians a new tool in the management of this common injury...
  44. doi request reprint Time interval between concussions and symptom duration
    Matthew A Eisenberg
    Division of Emergency Medicine, Boston Children s Hospital, Boston, MA 02115, USA
    Pediatrics 132:8-17. 2013
    ..To test the hypothesis that children with a previous history of concussion have a longer duration of symptoms after a repeat concussion than those without such a history...