Tao Liu

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Cistrome: an integrative platform for transcriptional regulation studies
    Tao Liu
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute and Harvard School of Public Health, Boston, MA 02215, USA
    Genome Biol 12:R83. 2011
  2. pmc MM-ChIP enables integrative analysis of cross-platform and between-laboratory ChIP-chip or ChIP-seq data
    Yiwen Chen
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute and Harvard School of Public Health, 44 Binney Street, Boston, MA 02115, USA
    Genome Biol 12:R11. 2011
  3. pmc Systematic evaluation of factors influencing ChIP-seq fidelity
    Yiwen Chen
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Nat Methods 9:609-14. 2012
  4. pmc Model-based analysis of ChIP-Seq (MACS)
    Yong Zhang
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute and Harvard School of Public Health, Boston, MA 02115, USA
    Genome Biol 9:R137. 2008
  5. doi request reprint CEAS: cis-regulatory element annotation system
    Hyunjin Shin
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    Bioinformatics 25:2605-6. 2009
  6. pmc EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent
    Kexin Xu
    Center for Functional Cancer Epigenetics, Dana Farber Cancer Institute, Boston, MA 02215, USA
    Science 338:1465-9. 2012
  7. pmc Broad chromosomal domains of histone modification patterns in C. elegans
    Tao Liu
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute and Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Genome Res 21:227-36. 2011

Collaborators

Detail Information

Publications7

  1. pmc Cistrome: an integrative platform for transcriptional regulation studies
    Tao Liu
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute and Harvard School of Public Health, Boston, MA 02215, USA
    Genome Biol 12:R83. 2011
    ..Cistrome is available at http://cistrome.org/ap/...
  2. pmc MM-ChIP enables integrative analysis of cross-platform and between-laboratory ChIP-chip or ChIP-seq data
    Yiwen Chen
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute and Harvard School of Public Health, 44 Binney Street, Boston, MA 02115, USA
    Genome Biol 12:R11. 2011
    ..It improves both the sensitivity and the specificity of detecting ChIP-enriched regions, and is a useful meta-analysis tool for driving discoveries from multiple data sources...
  3. pmc Systematic evaluation of factors influencing ChIP-seq fidelity
    Yiwen Chen
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Nat Methods 9:609-14. 2012
    ..Evaluation of widely used ChIP-seq analysis tools suggests that adjustments or algorithm improvements are required to handle data sets with deep coverage...
  4. pmc Model-based analysis of ChIP-Seq (MACS)
    Yong Zhang
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute and Harvard School of Public Health, Boston, MA 02115, USA
    Genome Biol 9:R137. 2008
    ..MACS also uses a dynamic Poisson distribution to effectively capture local biases in the genome, allowing for more robust predictions. MACS compares favorably to existing ChIP-Seq peak-finding algorithms, and is freely available...
  5. doi request reprint CEAS: cis-regulatory element annotation system
    Hyunjin Shin
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    Bioinformatics 25:2605-6. 2009
    ....
  6. pmc EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent
    Kexin Xu
    Center for Functional Cancer Epigenetics, Dana Farber Cancer Institute, Boston, MA 02215, USA
    Science 338:1465-9. 2012
    ..Hence, targeting the non-PRC2 function of EZH2 may have therapeutic efficacy for treating metastatic, hormone-refractory prostate cancer...
  7. pmc Broad chromosomal domains of histone modification patterns in C. elegans
    Tao Liu
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute and Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Genome Res 21:227-36. 2011
    ..These data, which confirm and extend previous studies, allow for in-depth analysis of the organization and deployment of the C. elegans genome during development...