Kathryn E Lewandowski
Affiliation: Harvard University
- Relationship of catechol-O-methyltransferase to schizophrenia and its correlates: evidence for associations and complex interactionsKathryn E Lewandowski
Harvard Medical School and Department of Psychology, McLean Hospital, Belmont, MA 02478, USA
Harv Rev Psychiatry 15:233-44. 2007..Additionally, evidence for complex interactions involving COMT is examined, including the utility of haplotype analysis and evidence for gene-by-gene and gene-by-environment interactions...
- Is cognitive enhancement therapy equally effective for patients with schizophrenia and schizoaffective disorder?Kathryn E Lewandowski
Schizophrenia and Bipolar Disorder Program, McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
Schizophr Res 125:291-4. 2011..Both patient groups improved in multiple domains after CET, and diagnosis did not significantly moderate this relationship. Extending CR to all patients in which cognitive dysfunction is a core feature may be indicated...
- Cognitive remediation versus active computer control in bipolar disorder with psychosis: study protocol for a randomized controlled trialKathryn Eve Lewandowski
McLean Hospital Harvard Medical School, 115 Mill St, Belmont, MA, 02478, USA
Trials 17:136. 2016..However, despite similar neurocognitive deficits between patients with schizophrenia and bipolar disorder, few studies have extended neuroscience-based cognitive remediation programs to this population...
- Age as a predictor of cognitive decline in bipolar disorderKathryn E Lewandowski
Schizophrenia and Bipolar Disorder Program, McLean Hospital, Belmont, MA Department of Psychiatry, Harvard Medical School, Boston, MA Electronic address
Am J Geriatr Psychiatry 22:1462-8. 2014..This cross-sectional study examined the relationship between age and cognitive functioning in patients with BD...
- Neuropsychological functioning predicts community outcomes in affective and non-affective psychoses: a 6-month follow-upKathryn E Lewandowski
Schizophrenia and Bipolar Disorder Program, McLean Hospital, 115 Mill St, Belmont, MA 02478 USA
Schizophr Res 148:34-7. 2013..We examined neurocognitive, clinical, and community functioning in a cross-diagnostic sample of patients with psychotic disorders over a 6-month follow-up interval...
- Relationship of neurocognitive deficits to diagnosis and symptoms across affective and non-affective psychosesKathryn E Lewandowski
Schizophrenia and Bipolar Disorder Program, McLean Hospital, 115 Mill St, Belmont, MA, 02478 USA
Schizophr Res 133:212-7. 2011..Additionally, we predicted that negative symptoms but not positive, general, or mood symptoms, would be associated with neurocognitive functioning...
- Tactile, olfactory, and gustatory hallucinations in psychotic disorders: a descriptive studyKathryn E Lewandowski
McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
Ann Acad Med Singapore 38:383-5. 2009..The present study examined hallucinations across sensory modalities in patients with primary psychotic disorders by diagnosis and in association with mood and psychotic symptoms...
- Evolution of neuropsychological dysfunction during the course of schizophrenia and bipolar disorderK E Lewandowski
McLean Hospital and Harvard Medical School, Boston, MA 02478, USA
Psychol Med 41:225-41. 2011....
- Categorical vs dimensional classifications of psychotic disordersMelissa Potuzak
Psychotic Disorders Division, McLean Hospital, 1125 Mill St, Belmont, MA 02478, USA
Compr Psychiatry 53:1118-29. 2012..This review examines the evidence on specific dimensions and categories that would best characterize psychoses...
- Auditory hallucinations in a cross-diagnostic sample of psychotic disorder patients: a descriptive, cross-sectional studyAnn K Shinn
Schizophrenia and Bipolar Disorder Program, McLean Hospital and Harvard Medical School, Department of Psychiatry, USA
Compr Psychiatry 53:718-26. 2012..Auditory hallucinations (AH) are a cardinal feature of schizophrenia spectrum disorders. They are not disease specific, however, and can occur in other conditions, including affective psychoses...
- Cognitive Remediation for the Treatment of Cognitive Dysfunction in the Early Course of PsychosisKathryn E Lewandowski
From Harvard Medical School and the Schizophrenia and Bipolar Disorder Program, McLean Hospital, Belmont, MA
Harv Rev Psychiatry 24:164-72. 2016..Additionally, a growing literature using neuroimaging techniques demonstrates the ability of cognitive remediation paradigms to engage neural targets. ..
- Measuring Cognition in Bipolar Disorder with Psychosis Using the MATRICS Consensus Cognitive BatterySarah H Sperry
1Schizophrenia and Bipolar Disorder Program, McLean Hospital, Belmont, Massachusetts
J Int Neuropsychol Soc 21:468-72. 2015..The MCCB is an appropriate measure of neurocognition in BDP but does not appear to capture social cognitive deficits in this population. The addition of appropriate social cognitive measures is recommended...
- Myelin vs axon abnormalities in white matter in bipolar disorderKathryn E Lewandowski
1 McLean Hospital Schizophrenia and Bipolar Disorder Program, Belmont, MA, USA 2 McLean Hospital, Harvard Medical School, Boston, MA, USA
Neuropsychopharmacology 40:1243-9. 2015..This difference may indicate that alterations in WM in BDP may have unique causes and may be less extensive than WM abnormalities seen in SZ. ..
- McLean OnTrack: a transdiagnostic program for early intervention in first-episode psychosisAnn K Shinn
McLean OnTrack, Psychotic Disorders Division, McLean Hospital, Boston, MA, USA
Early Interv Psychiatry 11:83-90. 2017..However, many early psychosis patients do not fit into this diagnostic category. Here we describe McLean OnTrack, an intensive outpatient treatment program that accepts all comers with first-episode psychosis...
- Reward Learning, Neurocognition, Social Cognition, and Symptomatology in PsychosisKathryn E Lewandowski
Schizophrenia and Bipolar Disorder Program, McLean Hospital, Belmont, MA, USA Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Front Psychiatry 7:100. 2016..However, whether reward processing and cognition are associated across the psychoses and linked to state and trait clinical symptomatology is unclear...
- Social functioning and age across affective and nonaffective psychosesElizabeth A Martin
Department of Psychology and Social Behavior, University of California, Irvine Schizophrenia and Bipolar Disorder Program, McLean Hospital, Belmont, MA and Department of Psychiatry, Harvard Medical School, Boston, MA
J Nerv Ment Dis 203:37-42. 2015..Overall, these results indicate that early interventions targeting social functioning may benefit individuals with either non-affective or affective psychoses to slow a projected decline. ..
- Diffusion tensor imaging in first degree relatives of schizophrenia and bipolar disorder patientsHidayet E Arat
Dokuz Eylul University, Faculty of Medicine, Department of Psychiatry, Izmir, Turkey McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
Schizophr Res 161:329-39. 2015..In this review, we evaluate published diffusion tensor imaging (DTI) studies comparing first degree relatives of SZ and BD patients and healthy control subjects...