Genomes and Genes
G W Lee
Affiliation: Harvard University
- Modification of Ran GTPase-activating protein by the small ubiquitin-related modifier SUMO-1 requires Ubc9, an E2-type ubiquitin-conjugating enzyme homologueG W Lee
Brigham and Women s Hospital, Division of Rheumatology, Boston, Massachusetts 02115, USA
J Biol Chem 273:6503-7. 1998..Finally, HsUbc9 is required for the modification of RanGAP1 by SUMO-1. These results suggest that HsUbc9 is a component of a novel enzymatic cascade that modifies RanGAP1, and possibly other substrates, with SUMO-1...