Genomes and Genes
T G Kroll
Affiliation: Harvard University
- PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma [corrected]T G Kroll
Department of Pathology, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Science 289:1357-60. 2000..The experiments demonstrate an oncogenic role for PPARgamma and suggest that PAX8-PPARgamma1 may be useful in the diagnosis and treatment of thyroid carcinoma...
- BRD4 bromodomain gene rearrangement in aggressive carcinoma with translocation t(15;19)C A French
Department of Pathology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Am J Pathol 159:1987-92. 2001..Our studies shed light on the oncogenic mechanism underlying t(15;19) and provide further evidence that this highly lethal cancer arises from respiratory mucosa...
- Transcriptional repression and developmental functions of the atypical vertebrate GATA protein TRPS1T H Malik
Department of Adult Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
EMBO J 20:1715-25. 2001..TRPS1 is the first example of a GATA protein with intrinsic transcriptional repression activity and possibly a negative regulator of GATA-dependent processes in vertebrate development...