Mark E Josephson

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Resetting and entrainment of reentrant ventricular tachycardia associated with myocardial infarction
    Mark E Josephson
    Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts Harvard Thorndike Electrophysiology Institute and Arrhythmia Service, Beth Israel Deaconess Medical Center, Boston, Massachusetts Harvard Medical School, Boston, Massachusetts Electronic address
    Heart Rhythm 11:1239-49. 2014
  2. ncbi request reprint Using the twelve-lead electrocardiogram to localize the site of origin of ventricular tachycardia
    Mark E Josephson
    Division of Cardiovascular Diseases, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Heart Rhythm 2:443-6. 2005
  3. ncbi request reprint Electrophysiology at a crossroads
    Mark E Josephson
    Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Heart Rhythm 4:658-61. 2007
  4. ncbi request reprint Electrophysiology of ventricular tachycardia: a historical perspective
    Mark E Josephson
    Department of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Pacing Clin Electrophysiol 26:2052-67. 2003
  5. ncbi request reprint Electrophysiology of ventricular tachycardia: an historical perspective
    Mark E Josephson
    Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Cardiovasc Electrophysiol 14:1134-48. 2003
  6. doi request reprint Predicting irreversible left ventricular dysfunction after acute myocardial infarction
    Daniel R Frisch
    Division of Cardiology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Am J Cardiol 103:1206-9. 2009
  7. pmc Recurrence of atrial fibrillation correlates with the extent of post-procedural late gadolinium enhancement: a pilot study
    Dana C Peters
    Department of Medicine Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    JACC Cardiovasc Imaging 2:308-16. 2009
  8. ncbi request reprint Limitations of ejection fraction for prediction of sudden death risk in patients with coronary artery disease: lessons from the MUSTT study
    Alfred E Buxton
    Department of Medicine, Cardiology Division, Brown Medical School and Lifespan Academic Medical Center, Providence, Rhode Island 02905, USA
    J Am Coll Cardiol 50:1150-7. 2007
  9. doi request reprint Improved multimodality data fusion of late gadolinium enhancement MRI to left ventricular voltage maps in ventricular tachycardia ablation
    Sebastien Roujol
    Department of Medicine Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    IEEE Trans Biomed Eng 60:1308-17. 2013
  10. doi request reprint Aortic injury is common following pulmonary vein isolation
    Patricia Tung
    Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Heart Rhythm 10:653-8. 2013

Detail Information

Publications99

  1. doi request reprint Resetting and entrainment of reentrant ventricular tachycardia associated with myocardial infarction
    Mark E Josephson
    Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts Harvard Thorndike Electrophysiology Institute and Arrhythmia Service, Beth Israel Deaconess Medical Center, Boston, Massachusetts Harvard Medical School, Boston, Massachusetts Electronic address
    Heart Rhythm 11:1239-49. 2014
    ..The terms for these techniques are often incorrectly used interchangeably. The present review details the characteristics and uses of both stimulation techniques. ..
  2. ncbi request reprint Using the twelve-lead electrocardiogram to localize the site of origin of ventricular tachycardia
    Mark E Josephson
    Division of Cardiovascular Diseases, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Heart Rhythm 2:443-6. 2005
  3. ncbi request reprint Electrophysiology at a crossroads
    Mark E Josephson
    Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Heart Rhythm 4:658-61. 2007
  4. ncbi request reprint Electrophysiology of ventricular tachycardia: a historical perspective
    Mark E Josephson
    Department of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Pacing Clin Electrophysiol 26:2052-67. 2003
  5. ncbi request reprint Electrophysiology of ventricular tachycardia: an historical perspective
    Mark E Josephson
    Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Cardiovasc Electrophysiol 14:1134-48. 2003
  6. doi request reprint Predicting irreversible left ventricular dysfunction after acute myocardial infarction
    Daniel R Frisch
    Division of Cardiology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
    Am J Cardiol 103:1206-9. 2009
    ..3. The presence of all 3 features had a positive predictive value of 100%. These findings may identify a high-risk group of patients who might benefit from early aggressive therapy such as an implantable cardioverter-defibrillator...
  7. pmc Recurrence of atrial fibrillation correlates with the extent of post-procedural late gadolinium enhancement: a pilot study
    Dana C Peters
    Department of Medicine Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    JACC Cardiovasc Imaging 2:308-16. 2009
    ..We sought to evaluate radiofrequency (RF) ablation lesions in atrial fibrillation (AF) patients using cardiac magnetic resonance (CMR), and to correlate the ablation patterns with treatment success...
  8. ncbi request reprint Limitations of ejection fraction for prediction of sudden death risk in patients with coronary artery disease: lessons from the MUSTT study
    Alfred E Buxton
    Department of Medicine, Cardiology Division, Brown Medical School and Lifespan Academic Medical Center, Providence, Rhode Island 02905, USA
    J Am Coll Cardiol 50:1150-7. 2007
    ..We then constructed an algorithm to predict risk of mortality and sudden death...
  9. doi request reprint Improved multimodality data fusion of late gadolinium enhancement MRI to left ventricular voltage maps in ventricular tachycardia ablation
    Sebastien Roujol
    Department of Medicine Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    IEEE Trans Biomed Eng 60:1308-17. 2013
    ..The proposed data fusion system allows the fusion of EAVM and LGE-MRI data in VT ablation with registration errors less than 3.5  mm...
  10. doi request reprint Aortic injury is common following pulmonary vein isolation
    Patricia Tung
    Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Heart Rhythm 10:653-8. 2013
    ..Hyperenhancement of the aorta is occasionally seen on cardiac magnetic resonance imaging with late gadolinium enhancement (CMR LGE) in patients undergoing PVI...
  11. pmc Bi-directional electrical pulmonary vein isolation as an endpoint for ablation of paroxysmal atrial fibrillation
    Vidal Essebag
    Harvard Thorndike Electrophysiology Institute Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, MA, USA
    J Interv Card Electrophysiol 17:111-7. 2006
    ..The purpose of this study is to report the efficacy and safety of routine isolation of all PVs using an endpoint of bi-directional electrical block...
  12. ncbi request reprint Early recurrence of arrhythmia in patients taking amiodarone or class 1C agents for treatment of atrial fibrillation or atrial flutter
    Thomas H Hauser
    Cardiovascular Division, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 93:1173-6. 2004
    ..Recurrent arrhythmia was not more common with amiodarone...
  13. pmc A swine model of infarct-related reentrant ventricular tachycardia: Electroanatomic, magnetic resonance, and histopathological characterization
    Cory M Tschabrunn
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Department of Medicine
    Heart Rhythm 13:262-73. 2016
    ..Several preclinical large animal models have been used to further study postinfarct reentrant VT, but with varied experimental methodologies and limited evaluation of the underlying substrate or induced arrhythmia mechanism...
  14. ncbi request reprint Patterns and predictors of warfarin use in patients with new-onset atrial fibrillation from the FRACTAL Registry
    Matthew R Reynolds
    Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 97:538-43. 2006
    ..The discontinuation of warfarin in a large number of patients with AF over time is a cause for concern in light of data from recent clinical trials...
  15. pmc Free-breathing cardiac MR with a fixed navigator efficiency using adaptive gating window size
    Mehdi H Moghari
    Department of Medicine, Cardiovascular Division, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Magn Reson Med 68:1866-75. 2012
    ..The results demonstrate that the proposed technique allows free-breathing cardiac MRI in a relatively fixed time without compromising imaging quality due to respiratory motion artifacts...
  16. ncbi request reprint Electrocardiographic predictors of arrhythmic death and total mortality in the multicenter unsustained tachycardia trial
    Peter J Zimetbaum
    Beth Israel Deaconess Medical Center, 185 Pilgrim Rd, Boston, Mass 02215, USA
    Circulation 110:766-9. 2004
    ..We assessed the prognostic significance of ECG markers of conduction abnormalities and left ventricular hypertrophy in the Multicenter Unsustained Tachycardia Trial (MUSTT)...
  17. ncbi request reprint Combined epicardial and endocardial electroanatomic mapping in a porcine model of healed myocardial infarction
    Vivek Y Reddy
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Circulation 107:3236-42. 2003
    ..This study sought to determine whether the epicardial extent of a myocardial infarct could be defined during sinus rhythm...
  18. doi request reprint Comparison of intracardiac echocardiography and transesophageal echocardiography for imaging of the right and left atrial appendages
    Elad Anter
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Electronic address
    Heart Rhythm 11:1890-7. 2014
    ..Intracardiac echocardiography (ICE) is routinely used during these procedures and may provide an alternative imaging modality...
  19. ncbi request reprint Catheter ablation of ventricular epicardial tissue: a comparison of standard and cooled-tip radiofrequency energy
    Andre d'Avila
    Cardiac Arrhythmia Service, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    Circulation 109:2363-9. 2004
    ..This experimental animal study examines the biophysical characteristics of radiofrequency (RF) ablation lesions generated by either standard or cooled-tip ablation of the ventricular epicardium...
  20. pmc Non-inducibility post-pulmonary vein isolation achieving exit block predicts freedom from atrial fibrillation
    Vidal Essebag
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deaconess Medical Center, 185 Pilgrim Road, Baker 4, Boston, MA 02215, USA
    Eur Heart J 26:2550-5. 2005
    ..This study evaluates whether non-inducibility of atrial fibrillation (AF) after achieving bi-directional electrical pulmonary vein (PV) isolation is a useful predictor of freedom from AF recurrence...
  21. pmc Prophylactic catheter ablation for the prevention of defibrillator therapy
    Vivek Y Reddy
    Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, USA
    N Engl J Med 357:2657-65. 2007
    ..We designed this randomized trial to examine whether prophylactic radiofrequency catheter ablation of arrhythmogenic ventricular tissue would reduce the incidence of ICD therapy...
  22. pmc Pulmonary vein inflow artifact reduction for free-breathing left atrium late gadolinium enhancement
    Mehdi H Moghari
    Department of Medicine, Cardiovascular Division, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Magn Reson Med 66:180-6. 2011
    ..5 vs. 3.1 ± 0.5 for projection vs. pencil-beam navigator). The proposed method greatly reduces the inflow artifact in free-breathing pulmonary vein late gadolinium enhancement while allowing adequate respiratory motion compensation...
  23. ncbi request reprint A method for the determination of proximal pulmonary vein size using contrast-enhanced magnetic resonance angiography
    Thomas H Hauser
    Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Cardiovasc Magn Reson 6:927-36. 2004
    ..We sought to develop a reproducible method for characterizing the anatomy of the proximal pulmonary veins...
  24. doi request reprint Pulmonary vein isolation using the Rhythmia mapping system: Verification of intracardiac signals using the Orion mini-basket catheter
    Elad Anter
    Cardiovascular Division, Department of Medicine, Harvard Thorndike Electrophysiology Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Electronic address
    Heart Rhythm 12:1927-34. 2015
    ..The Rhythmia mapping system uses the Orion mini-basket catheter with 64 electrodes instead of the lasso catheter. However, its feasibility to determine PVI has not been studied...
  25. doi request reprint The role of electrophysiology study in risk stratification of sudden cardiac death
    Karen E Thomas
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Prog Cardiovasc Dis 51:97-105. 2008
    ..Furthermore, expanding the role of the electrophysiology study to include therapeutic ablations may alter a patient's future risk of sudden cardiac death...
  26. ncbi request reprint Detection of pulmonary vein and left atrial scar after catheter ablation with three-dimensional navigator-gated delayed enhancement MR imaging: initial experience
    Dana C Peters
    Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, RW 453, Boston, MA 02215, USA
    Radiology 243:690-5. 2007
    ..To prospectively evaluate whether scar caused by radiofrequency (RF) ablation of the left atrium (LA) in patients with atrial fibrillation can be depicted with high-spatial-resolution delayed enhancement magnetic resonance (MR) imaging...
  27. doi request reprint Left atrial function and scar after catheter ablation of atrial fibrillation
    John V Wylie
    Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Heart Rhythm 5:656-62. 2008
    ..Catheter ablation of atrial fibrillation (AF) involves extensive radiofrequency ablation (RFA) of the left atrium (LA) around the pulmonary veins. The effect of this therapy on LA function is not fully characterized...
  28. doi request reprint Radiofrequency ablation annotation algorithm reduces the incidence of linear gaps and reconnection after pulmonary vein isolation
    Elad Anter
    Harvard Thorndike Electrophysiology Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Electronic address
    Heart Rhythm 11:783-90. 2014
    ..A common mechanism of atrial fibrillation recurrence after catheter ablation is resumption of pulmonary vein (PV) conduction due to gaps in the ablation line. These gaps may go unrecognized owing to inadequate ablation lesion annotation...
  29. pmc Global Electric Heterogeneity Risk Score for Prediction of Sudden Cardiac Death in the General Population: The Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies
    Jonathan W Waks
    From Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA J W W, A E B, M E J Cardiovascular Health Research Unit, Division of Cardiology, and Department of Epidemiology C M S, M L B, N S, D S S and Department of Biostatistics M L B, University of Washington, Seattle Epidemiological Cardiology Research Center, Division of Public Health Sciences and Department of Medicine, Cardiology Section, Wake Forest School of Medicine, Winston Salem, NC E Z S Knight Cardiovascular Institute, Oregon Health and Science University, Portland M K, E G, C A H, L G T Brigham and Women s Hospital, Harvard Medical School, Boston, MA T B S, S D S Department of Epidemiology, Internal Medicine and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins School of Public Health, Baltimore, MD S K A New York Academy of Medicine, New York D S S and Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD W S P, L G T
    Circulation 133:2222-34. 2016
    ..Asymptomatic individuals account for the majority of sudden cardiac deaths (SCDs). Development of effective, low-cost, and noninvasive SCD risk stratification tools is necessary...
  30. ncbi request reprint Characterization of the infarct substrate and ventricular tachycardia circuits with noncontact unipolar mapping in a porcine model of myocardial infarction
    Jason T Jacobson
    Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Heart Rhythm 3:189-97. 2006
    ..Conventional mapping of ventricular tachycardia (VT) after myocardial infarction is limited in patients with hemodynamically untolerated or noninducible VT...
  31. pmc Relationship between intended sites of RF ablation and post-procedural scar in AF patients, using late gadolinium enhancement cardiovascular magnetic resonance
    Jason E Taclas
    Department of Medicine Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Heart Rhythm 7:489-96. 2010
    ..Direct comparisons between the locations of intended RF ablation sites and locations of scar formation in the LA have not been performed...
  32. ncbi request reprint Atrioventricular nodal reentrant tachycardia associated with idiopathic ventricular tachycardia: clinical and electrophysiologic characteristics
    John V Wylie
    Cardiovascular Division, Harvard Thorndike Electrophysiology Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    J Electrocardiol 40:94-9. 2007
    ..This study examines the frequency of dual atrioventricular nodal (AVN) physiology, AVN echo beats, and atrioventricular nodal reentrant tachycardia (AVNRT) in patients with VT...
  33. ncbi request reprint Relationship of baseline electrocardiographic characteristics with the response to cardiac resynchronization therapy for heart failure
    Matthew R Reynolds
    Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Pacing Clin Electrophysiol 27:1513-8. 2004
    ..ECG markers of anterior infarction and RV dilation may help identify CHF patients unlikely to benefit from biventricular pacing. Further assessment is needed of these and other predictors of therapeutic response to CRT...
  34. pmc Inducibility of atrial fibrillation with a synchronized external low energy shock post-pulmonary vein isolation predicts recurrent atrial fibrillation
    John V Wylie
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Cardiovasc Electrophysiol 20:29-36. 2009
    ..Inducibility of atrial fibrillation (AF) with burst pacing after pulmonary vein (PV) isolation is associated with recurrent AF...
  35. doi request reprint Association of impaired thrombolysis in myocardial infarction myocardial perfusion grade with ventricular tachycardia and ventricular fibrillation following fibrinolytic therapy for ST-segment elevation myocardial infarction
    C Michael Gibson
    TIMI Study Group, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 51:546-51. 2008
    ..The goal of this analysis was to evaluate the association of impaired Thrombolysis In Myocardial Infarction myocardial perfusion grade (TMPG) with sustained ventricular tachycardia (VT) or ventricular fibrillation (VF)...
  36. pmc High-Resolution Mapping of Postinfarction Reentrant Ventricular Tachycardia: Electrophysiological Characterization of the Circuit
    Elad Anter
    From Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
    Circulation 134:314-27. 2016
    ..We used a novel high-resolution mapping technology to characterize the electrophysiological properties of the postinfarction reentrant VT circuit...
  37. doi request reprint Left ventricular sphericity independently predicts appropriate implantable cardioverter-defibrillator therapy
    Yehoshua C Levine
    Department of Medicine Cardiovascular Institute, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts
    Heart Rhythm 13:490-7. 2016
    ..Whether echocardiographic markers of remodeling are associated with ventricular tachyarrhythmias is unknown...
  38. doi request reprint Vectorcardiographic and electrocardiographic criteria to distinguish new and old left bundle branch block
    Alexei Shvilkin
    South Shore Hospital, South Weymouth, Massachusetts, USA
    Heart Rhythm 7:1085-92. 2010
    ..There are no established criteria to differentiate new from old left bundle branch block (LBBB). This complicates management of patients with LBBB and suspected acute coronary syndrome...
  39. doi request reprint Late gadolinium enhancement of the esophagus is common on cardiac MR several months after pulmonary vein isolation: preliminary observations
    Joyce Meng
    Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Pacing Clin Electrophysiol 33:661-6. 2010
    ..Late gadolinium enhancement (LGE) cardiovascular magnetic resonance imaging (CMR) offers noninvasive assessment of scar. We sought to examine the prevalence of esophageal hyperenhancement on LGE-CMR prior to and following PVI...
  40. ncbi request reprint Safety and feasibility of a clinical pathway for the outpatient initiation of antiarrhythmic medications in patients with atrial fibrillation or atrial flutter
    Thomas H Hauser
    Cardiovascular Division, Department of Medicine, Baker 4, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Am J Cardiol 91:1437-41. 2003
    ..Most adverse events occurred beyond the usual time period for in-hospital monitoring of the initiation of AAMs...
  41. ncbi request reprint Variation in pulmonary vein size during the cardiac cycle: implications for non-electrocardiogram-gated imaging
    Thomas H Hauser
    Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Am Heart J 152:974.e1-6. 2006
    ....
  42. pmc Volumetric left ventricular ejection fraction is superior to 2-dimensional echocardiography for risk stratification of patients for primary prevention implantable cardioverter-defibrillator implantation
    Hussein Rayatzadeh
    Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Am J Cardiol 111:1175-9. 2013
    ..In conclusion, if confirmed by larger prospective series, volumetric methods such as CMR should be considered a superior "gatekeeper" for the identification of patients likely to benefit from primary prevention ICD implantation...
  43. pmc Characteristics and outcomes of patients receiving new and replacement implantable cardioverter-defibrillators: results from the NCDR
    Daniel B Kramer
    Beth Israel Deaconess Medical Center, Boston, MA, USA
    Circ Cardiovasc Qual Outcomes 6:488-97. 2013
    ..Little is known about the clinical features, procedural risks, or survival of patients receiving replacement versus new implantable cardioverter-defibrillators (ICDs)...
  44. doi request reprint Treatment of obstructive sleep apnea reduces the risk of atrial fibrillation recurrence after catheter ablation
    Adam S Fein
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    J Am Coll Cardiol 62:300-5. 2013
    ..The aim of this study was to examine the effect of continuous positive airway pressure (CPAP) therapy on atrial fibrillation (AF) recurrence in patients with obstructive sleep apnea (OSA) undergoing pulmonary vein isolation (PVI)...
  45. ncbi request reprint Prognostic utility of comparative methods for assessment of ST-segment resolution after primary angioplasty for acute myocardial infarction: the Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC) trial
    Michael G McLaughlin
    Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Am Coll Cardiol 44:1215-23. 2004
    ..This study was done to assess and compare the prognostic significance of multiple methods for measuring ST-segment elevation resolution (STR) following primary percutaneous coronary intervention (PCI)...
  46. ncbi request reprint QRS duration does not predict occurrence of ventricular tachyarrhythmias in patients with implanted cardioverter-defibrillators
    Alfred E Buxton
    Cardiology Division, Department of Medicine, Brown Medical School, Providence, Rhode Island 02905, USA
    J Am Coll Cardiol 46:310-6. 2005
    ..The aim of this study was to determine whether QRS duration (QRSd) correlates with occurrence of ventricular arrhythmia in patients with coronary disease (CAD) receiving implantable cardioverter-defibrillators (ICDs)...
  47. doi request reprint A critical appraisal of implantable cardioverter-defibrillator therapy for the prevention of sudden cardiac death
    Roderick Tung
    Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Am Coll Cardiol 52:1111-21. 2008
    ..A reappraisal of the benefits and potential hazards of ICD therapy will enable physicians to a have a more mutually informed and balanced dialogue with their patients...
  48. ncbi request reprint Standard right atrial ablation is effective for atrioventricular nodal reentry with earliest activation in the coronary sinus
    Jane Chen
    Cardiovascular Division, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Cardiovasc Electrophysiol 15:2-7. 2004
    ..We assessed the efficacy of standard right atrial catheter ablation approaches in these tachycardias and determined the incidence of earliest activation in the CS in AVNRT...
  49. ncbi request reprint Alternating left bundle branch block and right bundle branch block during tachycardia: what is the mechanism?
    Daniel R Frisch
    Beth Israel Deaconess Medical Center, Department of Medicine, Boston, Massachusetts 02215, USA
    Heart Rhythm 4:679-80. 2007
  50. ncbi request reprint Two levels of block within a pulmonary vein
    Seth McClennen
    Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Am J Cardiol 94:412-3. 2004
    ..Conduction block within a PV electrically isolated from the left atrium is a newly observed phenomenon that may have implications to the electrophysiologic properties of the PV muscular sleeves...
  51. pmc Accelerated late gadolinium enhancement cardiac MR imaging with isotropic spatial resolution using compressed sensing: initial experience
    Mehmet Akçakaya
    Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Radiology 264:691-9. 2012
    ....
  52. pmc Cost-effectiveness of radiofrequency catheter ablation compared with antiarrhythmic drug therapy for paroxysmal atrial fibrillation
    Matthew R Reynolds
    Beth Israel Deaconess Medical Center, Boston, Mass 02215, USA
    Circ Arrhythm Electrophysiol 2:362-9. 2009
    ..The potential cost-effectiveness of RFA for AF, relative to antiarrhythmic drug (AAD) therapy, has not been fully explored from a US perspective...
  53. doi request reprint Painful left bundle branch block syndrome: Clinical and electrocardiographic features and further directions for evaluation and treatment
    Alexei Shvilkin
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts South Shore Hospital, South Weymouth, Massachusetts Electronic address
    Heart Rhythm 13:226-32. 2016
    ..Its prevalence, mechanism, detailed electrocardiographic (ECG) features, and effective treatments are not well described...
  54. pmc Prognostic value of pulmonary vein size in prediction of atrial fibrillation recurrence after pulmonary vein isolation: a cardiovascular magnetic resonance study
    Thomas H Hauser
    Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, RW 453, Boston, 02215, Massachusetts
    J Cardiovasc Magn Reson 17:49. 2015
    ..The relationship between pulmonary vein (PV) anatomy and successful catheter ablation of atrial fibrillation (AF) is poorly understood..
  55. doi request reprint Vectorcardiographic determinants of cardiac memory during normal ventricular activation and continuous ventricular pacing
    Alexei Shvilkin
    Department of Medicine Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Heart Rhythm 6:943-8. 2009
    ..Traditionally, to observe CM, normal ventricular activation had to be restored, limiting the exploration of this phenomenon in clinical practice...
  56. ncbi request reprint Cardiac memory induced by QRS widening due to propafenone toxicity
    John V Wylie
    Harvard Thorndike Electrophysiology Institute, Harvard Medical School, Boston, Massachusetts, USA
    Pacing Clin Electrophysiol 30:1161-4. 2007
    ..As her QRS complex narrowed, T-wave inversions developed with the T-wave axis and resolution kinetics consistent with CM. Abnormal ventricular activation due to propafenone toxicity can result in CM development...
  57. doi request reprint Nonreentrant ventricular arrhythmias in patients with structural heart disease unrelated to abnormal myocardial substrate
    Ethan R Ellis
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Electronic address
    Heart Rhythm 11:946-52. 2014
    ..Patients with structural heart disease have ventricular arrhythmias with the same mechanisms and sites of origin as idiopathic ventricular arrhythmias, but the prevalence of such arrhythmias is not well defined...
  58. doi request reprint Evaluation of a novel high-resolution mapping technology for ablation of recurrent scar-related atrial tachycardias
    Elad Anter
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Electronic address
    Heart Rhythm 13:2048-55. 2016
    ..Rhythmia is a new technology capable of rapid and high-resolution mapping. However, its potential advantage over existing technologies in mapping complex scar-related atrial tachycardias (ATs) has not yet been evaluated...
  59. doi request reprint Comparison between single- and multi-sensor oesophageal temperature probes during atrial fibrillation ablation: thermodynamic characteristics
    Cory M Tschabrunn
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, 185 Pilgrim Road, Baker 4, Boston, MA 02215, USA
    Europace 17:891-7. 2015
    ..Multi-sensor self-expandable probes (MSPs) may offer improved thermal monitoring. The objective of this study was to compare the thermodynamic characteristics of both probes during PVI...
  60. doi request reprint Six year follow-up after catheter ablation of atrial fibrillation: a palliation more than a true cure
    Antonio Sorgente
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 109:1179-86. 2012
    ..Strict clinical surveillance after catheter ablation should be considered to help guide clinical decisions...
  61. doi request reprint Self-terminated ventricular fibrillation and recurrent syncope
    Yuval Konstantino
    Cardiovascular Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 107:638-40. 2011
    ..In conclusion, self-terminating VF is a very rare condition that can cause syncope...
  62. pmc Accuracy of electrocardiographic criteria for atrial enlargement: validation with cardiovascular magnetic resonance
    Connie W Tsao
    Harvard Thorndike Laboratory and the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, Massachusetts, USA
    J Cardiovasc Magn Reson 10:7. 2008
    ..We sought to determine the accuracy of the ECG to predict anatomic atrial enlargement as determined by volumetric cardiovascular magnetic resonance (CMR)...
  63. ncbi request reprint T-vector direction differentiates postpacing from ischemic T-wave inversion in precordial leads
    Alexei Shvilkin
    Beth Israel Deaconess Medical Center, Boston, Mass 02215, USA
    Circulation 111:969-74. 2005
    ....
  64. ncbi request reprint Frequency and causes of implantable cardioverter-defibrillator therapies: is device therapy proarrhythmic?
    Joseph J Germano
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 97:1255-61. 2006
    ..These issues clearly affect the overall benefit of device therapy and have important implications for patient management and health care delivery...
  65. ncbi request reprint Impact of a practice guideline for patients with atrial fibrillation on medical resource utilization and costs
    Peter Zimetbaum
    Division of Cardiology, Beth Israel Deaconess Medical Center, One Deaconess Road, Boston, MA 02215, USA
    Am J Cardiol 92:677-81. 2003
    ..We conclude that the implementation of our practice guideline was feasible, safe, and effective. Widespread adoption of such practices may have large financial implications for the health care system...
  66. doi request reprint The year in arrhythmias 2007: Part II
    Mark E Josephson
    Department of Medicine, Cardiovascular Division Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Heart Rhythm 5:867-71. 2008
  67. doi request reprint The year in arrhythmias--2007: Part I
    Mark E Josephson
    Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Heart Rhythm 5:742-8. 2008
  68. doi request reprint Catheter ablation vs antiarrhythmic drug therapy for atrial fibrillation: a systematic review
    Amit Noheria
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Arch Intern Med 168:581-6. 2008
    ..We conducted a systematic literature review to assess whether CPVA is superior to ADT for the management of AF...
  69. ncbi request reprint Prognostic significance of nonsustained ventricular tachycardia identified postoperatively after coronary artery bypass surgery in patients with left ventricular dysfunction
    Luis A Pires
    Department of Medicine, St John Hospital and Medical Center and Wayne State University School of Medicine, Detroit, Michigan 48302, USA
    J Cardiovasc Electrophysiol 13:757-63. 2002
    ..The prognosis of NSVT in this setting in patients with left ventricular (LV) dysfunction is unknown. This study was designed to assess its significance...
  70. pmc High-Resolution Mapping of Ventricular Scar: Comparison Between Single and Multielectrode Catheters
    Cory M Tschabrunn
    From the Harvard Thorndike Electrophysiology Institute C M T, M E J, E A and Cardiovascular Division, Department of Medicine C M T, S R, R N, M E J, E A, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA and Biosense Webster, Johnson and Johnson, Diamond Bar, CA N C D
    Circ Arrhythm Electrophysiol 9:. 2016
    ..5-mm catheters (Smart-Touch Thermocool)...
  71. doi request reprint Acute pulmonary vein reconnection is a predictor of atrial fibrillation recurrence following pulmonary vein isolation
    Elad Anter
    Harvard Thorndike Electrophysiology Institute, Division of Cardiovascular Disease, Beth Israel Deaconess Medical Center, Harvard Medical School, 85 Pilgrim Road, Baker 4, Boston, MA, 02215, USA
    J Interv Card Electrophysiol 39:225-32. 2014
    ..The prognostic implications of detection and treatment of acute PV reconnection are not well understood. We aim to examine the prognostic significance of acute PV reconnection on arrhythmia recurrence at 1 year following PVI...
  72. ncbi request reprint Typical AVNRT--an update on mechanisms and therapy
    Kevin F Kwaku
    Harvard Thorndike Electrophysiology Institute and Arrhythmia Service, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Card Electrophysiol Rev 6:414-21. 2002
    ..Results from multiple series have shown this strategy to be both safe and effective, therefore ablation therapy should now be considered as the definitive therapy of choice for the majority of patients...
  73. ncbi request reprint Assessment of left atrial volume by contrast enhanced magnetic resonance angiography
    Thomas H Hauser
    Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    J Cardiovasc Magn Reson 6:491-7. 2004
    ..98, p < 0.001) with narrow 95% limits of agreement (-8 to 11 mL). The CE-MRA LA volumes correspond most closely to LA end-diastolic cine MR LA volumes and may be a useful measure of LA size...
  74. ncbi request reprint Concealed and manifest 1:2 tachycardia and atrioventricular nodal reentrant tachycardia: manifestations of dual atrioventricular nodal physiology
    Joseph J Germano
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Heart Rhythm 2:536-9. 2005
  75. doi request reprint Idiopathic ventricular fibrillation originating from the moderator band
    Elad Anter
    Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    J Cardiovasc Electrophysiol 24:97-100. 2013
    ..Ventricular fibrillation was pause-dependent and triggered by an early-coupled right ventricular premature complex. The characteristic premature beat was mapped and successfully ablated from Purkinje fibers of the moderator band...
  76. ncbi request reprint Delayed occurrence of unheralded phase IV complete heart block after ethanol septal ablation for symmetric hypertrophic obstructive cardiomyopathy
    Joanna J Wykrzykowska
    Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Pacing Clin Electrophysiol 29:674-8. 2006
    ....
  77. ncbi request reprint Variation in the utilization of antiarrhythmic drugs in patients with new-onset atrial fibrillation
    Peter Zimetbaum
    Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Clinical Research Institute, Boston, Massachusetts 02215, USA
    Am J Cardiol 91:81-3. 2003
  78. ncbi request reprint Use of the electrocardiogram in acute myocardial infarction
    Peter J Zimetbaum
    Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston 02215, USA
    N Engl J Med 348:933-40. 2003
  79. ncbi request reprint Use of electrogram characteristics during sinus rhythm to delineate the endocardial scar in a porcine model of healed myocardial infarction
    David Wrobleski
    Cardiac Arrhythmia Service, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
    J Cardiovasc Electrophysiol 14:524-9. 2003
    ..We sought to determine whether electrogram criteria during sinus rhythm could identify the location and extent of the myocardial scar by electroanatomic mapping...
  80. pmc Characterization of respiratory and cardiac motion from electro-anatomical mapping data for improved fusion of MRI to left ventricular electrograms
    Sebastien Roujol
    Department of Medicine Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 8:e78852. 2013
    ....
  81. ncbi request reprint Is there a role for maintaining sinus rhythm in patients with atrial fibrillation?
    Peter Zimetbaum
    Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Ann Intern Med 141:720-6. 2004
    ..This perspective argues for the maintenance of sinus rhythm and for the use of antiarrhythmic therapy that includes medications, invasive procedures, and a combination of both in appropriate patients...
  82. ncbi request reprint MADIT II (second Multicenter Automated Defibrillator Implantation Trial) debate: risk stratification, costs, and public policy
    Matthew R Reynolds
    Beth Israel Deaconess Medical Center, Boston, Mass 02215, USA
    Circulation 108:1779-83. 2003
  83. ncbi request reprint Effects of ventricular premature stimulus coupling interval on blood pressure and heart rate turbulence
    Mari A Watanabe
    Harvard Thorndike Institute of Electrophysiology, Beth Israel Deaconess Medical Center, Boston, Mass, USA
    Circulation 106:325-30. 2002
    ..On the basis of a study of ventricular premature complex coupling interval and sympathetic nerve burst amplitude, we hypothesized that measures of HRT would increase with increased prematurity of the coupling interval...
  84. ncbi request reprint Variable electrocardiographic characteristics of isthmus-dependent atrial flutter
    Paul Milliez
    Harvard Thorndike Electrophysiology Institute, Cardiovascular Division, Beth Israel Deacones Medical Center, Boston, Massashusetts 02215, USA
    J Am Coll Cardiol 40:1125-32. 2002
    ....
  85. doi request reprint Paroxysmal atrioventricular block
    Sinjin Lee
    Department of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Heart Rhythm 6:1229-34. 2009
    ....
  86. ncbi request reprint Images in cardiovascular medicine. Spontaneous onset of atrioventricular nodal reentrant tachycardia with high grade intranodal block
    Seth McClennen
    Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass 02215, USA
    Circulation 107:e57-62. 2003
  87. ncbi request reprint Atrial tachyarrhythmias after atrial fibrillation ablation procedures: trading one tachycardia for another?
    John V Wylie
    J Cardiovasc Electrophysiol 17:374-6. 2006
  88. pmc Sex differences in the relationship between amiodarone use and the need for permanent pacing in patients with atrial fibrillation
    Vidal Essebag
    Division of Cardiology, McGill University Health Center, Montreal, Quebec, Canada
    Arch Intern Med 167:1648-53. 2007
    ..The aims of this study were to determine prospectively whether amiodarone increases the need for pacemakers in a general population of patients with AF and whether this effect is modified by sex...
  89. ncbi request reprint Cardiac memory: mechanisms and clinical implications
    Kornelis W Patberg
    Department of Pharmacology, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Heart Rhythm 2:1376-82. 2005
    ..We also discuss the controversies regarding atrial memory and its potential clinical implications...
  90. ncbi request reprint Effect of implantable defibrillators on arrhythmic events and mortality in the multicenter unsustained tachycardia trial
    Kerry L Lee
    Department of Biostatistics and Bioinformatics, Duke University Medical Center, Duke Clinical Research Institute and Duke University School of Medicine, Durham, NC 27705, USA
    Circulation 106:233-8. 2002
    ..We performed several statistical analyses to assess the contribution of defibrillators to the observed treatment benefit...
  91. ncbi request reprint Relation of ejection fraction and inducible ventricular tachycardia to mode of death in patients with coronary artery disease: an analysis of patients enrolled in the multicenter unsustained tachycardia trial
    Alfred E Buxton
    Brown Medical School, Providence, RI, USA
    Circulation 106:2466-72. 2002
    ..As such, optimum methods to determine patients most likely to benefit from implantable defibrillator therapy are unclear...
  92. ncbi request reprint Amiodarone versus sotalol for atrial fibrillation
    Peter J Zimetbaum
    N Engl J Med 353:627-30; author reply 627-30. 2005
  93. ncbi request reprint All patients with hemodynamically tolerated postinfarction ventricular tachycardia do not require an implantable cardioverter-defibrillator
    Jesus Almendral
    Servicio de Cardiologia Planta 5, Hospital Gregorio Maranon, Doctor Esquerdo, 46, 28007 Madrid, Spain
    Circulation 116:1204-12. 2007
  94. ncbi request reprint The frustrating search for arrhythmia risk stratifiers in heart failure due to nonischemic cardiomyopathy: does T-wave alternans testing help?
    Richard L Verrier
    J Am Coll Cardiol 50:1905-6. 2007
  95. doi request reprint Orthodromic reciprocating tachycardia, in the presence of ipsilateral bundle branch block with a free-wall accessory pathway
    Eduard Sklyar
    Heart Rhythm 5:169; author reply 169-70. 2008
  96. ncbi request reprint T-wave alternans: does size matter
    Richard L Verrier
    J Cardiovasc Electrophysiol 16:625-8. 2005
  97. ncbi request reprint T-Wave alternans for arrhythmia risk stratification in patients with idiopathic dilated cardiomyopathy
    Richard L Verrier
    J Am Coll Cardiol 41:2225-7. 2003
  98. ncbi request reprint A new algorithm in the differential diagnosis of wide complex tachycardia
    Raghuveer Dendi
    Eur Heart J 28:525-6. 2007
  99. ncbi request reprint Effectiveness of catheter ablation of atrial fibrillation
    Vidal Essebag
    Eur Heart J 27:130-1. 2006