Yolonda L Colson

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Absence of clinical GVHD and the in vivo induction of regulatory T cells after transplantation of facilitating cells
    Yolonda L Colson
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Blood 104:3829-35. 2004
  2. ncbi request reprint Mixed xenogeneic chimerism induces donor-specific humoral and cellular immune tolerance for cardiac xenografts
    Yolonda L Colson
    Department of Surgery, Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Immunol 173:5827-34. 2004
  3. pmc Identification of metastatic nodal disease in a phase 1 dose-escalation trial of intraoperative sentinel lymph node mapping in non-small cell lung cancer using near-infrared imaging
    Denis M Gilmore
    Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Mass 02115, USA
    J Thorac Cardiovasc Surg 146:562-70; discussion 569-70. 2013
  4. doi request reprint Cytoreductive surgery and intraoperative administration of paclitaxel-loaded expansile nanoparticles delay tumor recurrence in ovarian carcinoma
    Denis Gilmore
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Ann Surg Oncol 20:1684-93. 2013
  5. pmc Prevention of nodal metastases in breast cancer following the lymphatic migration of paclitaxel-loaded expansile nanoparticles
    Rong Liu
    Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Biomaterials 34:1810-9. 2013
  6. doi request reprint Prevention of local tumor recurrence following surgery using low-dose chemotherapeutic polymer films
    Rong Liu
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Ann Surg Oncol 17:1203-13. 2010
  7. pmc Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers
    Jesse B Wolinsky
    Departments of Biomedical Engineering and Chemistry, Boston University, Boston, Massachusetts, USA
    J Control Release 159:14-26. 2012
  8. pmc Nanoparticle migration and delivery of Paclitaxel to regional lymph nodes in a large animal model
    Onkar V Khullar
    Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Am Coll Surg 214:328-37. 2012
  9. ncbi request reprint Induction of FoxP3+CD4+25+ regulatory T cells following hemopoietic stem cell transplantation: role of bone marrow-derived facilitating cells
    Kendra N Taylor
    Division of Thoracic Surgery, Department of Surgery Brigham and Women s Hospital, Boston, MA 02115, USA
    J Immunol 179:2153-62. 2007
  10. doi request reprint Paclitaxel-eluting polymer film reduces locoregional recurrence and improves survival in a recurrent sarcoma model: a novel investigational therapy
    Rong Liu
    Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Ann Surg Oncol 19:199-206. 2012

Collaborators

Detail Information

Publications45

  1. ncbi request reprint Absence of clinical GVHD and the in vivo induction of regulatory T cells after transplantation of facilitating cells
    Yolonda L Colson
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Blood 104:3829-35. 2004
    ..These findings suggest that the FCs, which express a unique FCp33-TCRbeta heterodimer in place of alphabetaTCR, permits HSC alloengraftment and prevents GVHD through the novel approach of regulatory T-cell induction in vivo...
  2. ncbi request reprint Mixed xenogeneic chimerism induces donor-specific humoral and cellular immune tolerance for cardiac xenografts
    Yolonda L Colson
    Department of Surgery, Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Immunol 173:5827-34. 2004
    ....
  3. pmc Identification of metastatic nodal disease in a phase 1 dose-escalation trial of intraoperative sentinel lymph node mapping in non-small cell lung cancer using near-infrared imaging
    Denis M Gilmore
    Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Mass 02115, USA
    J Thorac Cardiovasc Surg 146:562-70; discussion 569-70. 2013
    ....
  4. doi request reprint Cytoreductive surgery and intraoperative administration of paclitaxel-loaded expansile nanoparticles delay tumor recurrence in ovarian carcinoma
    Denis Gilmore
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Ann Surg Oncol 20:1684-93. 2013
    ..We hypothesize that local administration of paclitaxel-loaded expansile nanoparticles (pax-eNP) at the time of cytoreductive surgery decreases local tumor recurrence...
  5. pmc Prevention of nodal metastases in breast cancer following the lymphatic migration of paclitaxel-loaded expansile nanoparticles
    Rong Liu
    Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Biomaterials 34:1810-9. 2013
    ....
  6. doi request reprint Prevention of local tumor recurrence following surgery using low-dose chemotherapeutic polymer films
    Rong Liu
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Ann Surg Oncol 17:1203-13. 2010
    ..To evaluate the efficacy of a polymer film designed for prolonged paclitaxel release at surgical margins to prevent local recurrence in non-small-cell lung cancer (NSCLC) following complete surgical resection in a murine model...
  7. pmc Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers
    Jesse B Wolinsky
    Departments of Biomedical Engineering and Chemistry, Boston University, Boston, Massachusetts, USA
    J Control Release 159:14-26. 2012
    ..Finally, a discussion of the physiological barriers to localized therapy (i.e. drug penetration, transport), technical hurdles, and future outlook of the field is presented...
  8. pmc Nanoparticle migration and delivery of Paclitaxel to regional lymph nodes in a large animal model
    Onkar V Khullar
    Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Am Coll Surg 214:328-37. 2012
    ..The aim of this study was to demonstrate feasibility of migration and in situ chemotherapy delivery to regional lymph nodes (LN) in a large animal model using an expansile polymer nanoparticle (eNP) delivery system...
  9. ncbi request reprint Induction of FoxP3+CD4+25+ regulatory T cells following hemopoietic stem cell transplantation: role of bone marrow-derived facilitating cells
    Kendra N Taylor
    Division of Thoracic Surgery, Department of Surgery Brigham and Women s Hospital, Boston, MA 02115, USA
    J Immunol 179:2153-62. 2007
    ..The transplantation of donor FC may provide an alternative approach to permit clinical SC engraftment and induction of transplantation tolerance in the future...
  10. doi request reprint Paclitaxel-eluting polymer film reduces locoregional recurrence and improves survival in a recurrent sarcoma model: a novel investigational therapy
    Rong Liu
    Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Ann Surg Oncol 19:199-206. 2012
    ..Efficacy of a drug-eluting polymer film in reducing locoregional recurrence rates was assessed in a murine recurrent sarcoma model...
  11. doi request reprint Paclitaxel-loaded expansile nanoparticles delay local recurrence in a heterotopic murine non-small cell lung cancer model
    Rong Liu
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Ann Thorac Surg 91:1077-83; discussion 1083-4. 2011
    ..We hypothesized that local delivery of paclitaxel through 100-nm expansile polymer nanoparticles (pax-eNP) immediately after tumor resection could prevent local recurrence...
  12. doi request reprint Relationship between margin distance and local recurrence among patients undergoing wedge resection for small (≤2 cm) non-small cell lung cancer
    Kamran Mohiuddin
    Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Mass
    J Thorac Cardiovasc Surg 147:1169-75; discussion 1175-7. 2014
    ..Toward addressing this gap, we investigated the relationship between the margin distance and local recurrence risk...
  13. pmc Preclinical study of near-infrared-guided sentinel lymph node mapping of the porcine lung
    Onkar V Khullar
    Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Ann Thorac Surg 95:312-8. 2013
    ..Our objective was to develop a rapid, simple, and reliable method for thoracic sentinel lymph node (SLN) identification using near-infrared fluorescence imaging and clinically available contrast agents...
  14. ncbi request reprint Biologically responsive polymeric nanoparticles for drug delivery
    Yolonda L Colson
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston MA 02215, USA
    Adv Mater 24:3878-86. 2012
    ....
  15. doi request reprint Paclitaxel-loaded expansile nanoparticles in a multimodal treatment model of malignant mesothelioma
    Morgan D Schulz
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Ann Thorac Surg 92:2007-13; discussion 2013-4. 2011
    ..We therefore developed a murine model of multimodal therapy in which we evaluated paclitaxel-loaded expansile nanoparticles (Pax-eNP) for delivering intracavitary chemotherapy in malignant mesothelioma...
  16. pmc Induction of FoxP3+CD4+CD25+ regulatory T cells by a bone marrow population distinct from plasmacytoid-DC
    Kendra N Taylor
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Cell Immunol 251:43-9. 2008
    ....
  17. pmc Nanoparticle tumor localization, disruption of autophagosomal trafficking, and prolonged drug delivery improve survival in peritoneal mesothelioma
    Rong Liu
    Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Biomaterials 102:175-86. 2016
    ..As a result, overall survival of animals with established mesothelioma more than doubled when animals were treated with multiple doses of PTX-eNPs compared to equivalent dosing with PTX or non-responsive PTX-loaded nanoparticles. ..
  18. doi request reprint Effective low-dose escalation of indocyanine green for near-infrared fluorescent sentinel lymph node mapping in melanoma
    Denis M Gilmore
    Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Ann Surg Oncol 20:2357-63. 2013
    ..Near-infrared imaging (NIR) may utilize indocyanine green (ICG) to improve SLN identification. The safety, feasibility and optimal dose of albumin-bound ICG (ICG:HSA) was assessed by NIR to improve SLN mapping in patients with melanoma...
  19. doi request reprint Bronchopleural fistula and the role of contemporary imaging
    Puja Gaur
    Department of Thoracic Surgery, Brigham and Women s Hospital, Boston, Mass Electronic address
    J Thorac Cardiovasc Surg 148:341-7. 2014
    ..Better understanding of the potential uses and benefits of these techniques will eventually improve the diagnostic accuracy, optimize preoperative planning, and facilitate follow-up for patients with BPF with improved patient outcomes. ..
  20. doi request reprint The performance of expansile nanoparticles in a murine model of peritoneal carcinomatosis
    Yolonda L Colson
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    Biomaterials 32:832-40. 2011
    ....
  21. ncbi request reprint Facilitating cells: novel promoters of stem cell alloengraftment and donor-specific transplantation tolerance in the absence of GVHD
    Yolonda L Colson
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    Crit Rev Oncol Hematol 61:26-43. 2007
    ....
  22. doi request reprint Expansile nanoparticles: synthesis, characterization, and in vivo efficacy of an acid-responsive polymeric drug delivery system
    Aaron P Griset
    Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
    J Am Chem Soc 131:2469-71. 2009
    ..Expansile nanoparticles loaded with paclitaxel, a poorly water-soluble anticancer drug, prevent establishment of lung cancer in vivo and are superior to the conventional drug delivery method for paclitaxel using Cremophor EL/ethanol...
  23. pmc Microscopy and tunable resistive pulse sensing characterization of the swelling of pH-responsive, polymeric expansile nanoparticles
    Aaron H Colby
    Boston University, Boston, MA, USA
    Nanoscale 5:3496-504. 2013
    ..eNP swelling occurs in a continuous and yet heterogeneous manner over several days and is pH dependent...
  24. doi request reprint Developing intrathoracic sentinel lymph node mapping with near-infrared fluorescent imaging in non-small cell lung cancer
    Denis M Gilmore
    Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, MA, USA
    J Thorac Cardiovasc Surg 144:S80-4. 2012
    ..The early results in our recent clinical trial of patients with early-stage lung cancer have suggested that near-infrared imaging might offer a platform for reliable sentinel lymph node identification in these patients...
  25. pmc Superhydrophobic materials for tunable drug release: using displacement of air to control delivery rates
    Stefan T Yohe
    Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA
    J Am Chem Soc 134:2016-9. 2012
    ....
  26. pmc Nanotechnology applications in thoracic surgery
    Sophie C Hofferberth
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Eur J Cardiothorac Surg 50:6-16. 2016
    ..This article provides an overview of key existing and emerging nanotechnology platforms that may find clinical application in thoracic surgery in the near future. ..
  27. pmc From Diagnosis to Treatment: Clinical Applications of Nanotechnology in Thoracic Surgery
    Christopher S Digesu
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, 15 Francis St, Boston, MA 02115, USA
    Thorac Surg Clin 26:215-28. 2016
    ..This article reviews nanoplatforms, their unique properties, and the potential for clinical application in thoracic surgery. ..
  28. pmc Superhydrophobic materials for biomedical applications
    Eric J Falde
    Departments of Biomedical Engineering, Chemistry and Medicine, Boston University, 590 Commonwealth Avenue, Boston, MA, 02215, USA
    Biomaterials 104:87-103. 2016
    ....
  29. pmc Evaluation of expansile nanoparticle tumor localization and efficacy in a cancer stem cell-derived model of pancreatic peritoneal carcinomatosis
    Victoria Lm Herrera
    Department of Medicine and Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA 02118, USA
    Nanomedicine (Lond) 11:1001-15. 2016
    ..To evaluate the tumor localization and efficacy pH-responsive expansile nanoparticles (eNPs) as a drug delivery system for pancreatic peritoneal carcinomatosis (PPC) modeled in nude rats...
  30. doi request reprint Paclitaxel-loaded expansile nanoparticles enhance chemotherapeutic drug delivery in mesothelioma 3-dimensional multicellular spheroids
    Hongyi Lei
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, Mass Department of Anesthesiology, Zhujiang Hospital, Southern Medical University, Guangzhou, China
    J Thorac Cardiovasc Surg 149:1417-24; discussion 1424-25.e1. 2015
    ..Using a mesothelioma spheroid model, we characterized the mechanisms of enhanced tumor cytotoxicity leveraged by Pax-eNPs...
  31. pmc Stretch-Induced Drug Delivery from Superhydrophobic Polymer Composites: Use of Crack Propagation Failure Modes for Controlling Release Rates
    Julia Wang
    Departments of Biomedical Engineering and Chemistry, Boston University, Boston, MA, 02215, USA
    Angew Chem Int Ed Engl 55:2796-800. 2016
    ..Finally the device is integrated with an esophageal stent to demonstrate delivery of fluorescein diacetate, using applied tension, to an ex vivo esophagus...
  32. pmc Prevention of lung cancer recurrence using cisplatin-loaded superhydrophobic nanofiber meshes
    Jonah A Kaplan
    Department of Biomedical Engineering, Boston University, 590 Commonwealth Ave, Boston, MA 02215, USA Department of Chemistry, Boston University, 590 Commonwealth Ave, Boston, MA 02215, USA Department of Medicine, Boston University, 590 Commonwealth Ave, Boston, MA 02215, USA
    Biomaterials 76:273-81. 2016
    ..These results emphasize the importance of supplementing cytoreductive surgery with local drug delivery strategies to improve prognosis for lung cancer patients undergoing tumor resection...
  33. doi request reprint Synthesis and Characterization of Hybrid Polymer/Lipid Expansile Nanoparticles: Imparting Surface Functionality for Targeting and Stability
    Michelle Stolzoff
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02115, United States
    Biomacromolecules 16:1958-66. 2015
    ..The resulting hybrid polymer/lipid nanocarriers, FA-PEG-L-eNPs, exhibit greater in vitro uptake and potency when loaded with paclitaxel compared to nontargeted PEG-L-eNPs...
  34. doi request reprint Tumor targeted nanoparticles: a modern day Trojan horse
    Denis Gilmore
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    Semin Thorac Cardiovasc Surg 23:10-1. 2011
    ..Several recent timely reports summarize nanoparticle properties and potential clinical applications in early-stage clinical trials...
  35. ncbi request reprint Reconstitution of allogeneic hemopoietic stem cells: the essential role of FcR gamma and the TCR beta-chain-FCp33 complex
    Kendra N Taylor
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Immunol 177:1444-50. 2006
    ....
  36. doi request reprint Invited commentary
    Phillip L Camp
    Thoracic Surgery, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Ann Thorac Surg 85:1900. 2008
  37. doi request reprint Lobectomy versus sublobar resection for small (2 cm or less) non-small cell lung cancers
    Andrea S Wolf
    Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    Ann Thorac Surg 92:1819-23; discussion 1824-5. 2011
    ....
  38. pmc Nanotechnology in thoracic surgery
    Morgan D Schulz
    Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Ann Thorac Surg 89:S2188-90. 2010
    ..With promising preclinical results in many applications directly applicable to thoracic oncology, it is possible that the frontiers of minimally invasive thoracic surgery will eventually be explored at the nanoscale...
  39. doi request reprint Prevention of local tumor growth with paclitaxel-loaded microspheres
    Solomon M Azouz
    Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Mass 02115, USA
    J Thorac Cardiovasc Surg 135:1014-21. 2008
    ....
  40. pmc Safety and feasibility of near-infrared image-guided lymphatic mapping of regional lymph nodes in esophageal cancer
    Krista J Hachey
    Division of Thoracic Surgery, Brigham and Women s Hospital, Boston, Mass
    J Thorac Cardiovasc Surg 152:546-54. 2016
    ..To assess safety and feasibility of an intraoperative, minimally invasive near-infrared (NIR) image-guided approach to lymphatic mapping in patients with esophageal cancer...
  41. pmc Management of Sarcoma Metastases to the Lung
    Christopher S Digesu
    Division of Thoracic Surgery, Department of Surgery, Brigham and Women s Hospital, Harvard Medical School, 15 Francis Street, Boston, MA 02155, USA
    Surg Oncol Clin N Am 25:721-33. 2016
    ..In this review, the prognostic characteristics of pulmonary metastases from sarcoma, preoperative evaluation, operative technique, long-term outcomes, and management of complex patients are highlighted. ..
  42. pmc Embedded multicellular spheroids as a biomimetic 3D cancer model for evaluating drug and drug-device combinations
    Kristie M Charoen
    Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA
    Biomaterials 35:2264-71. 2014
    ....
  43. doi request reprint Recurrent chylous pericardial effusion and left neck mass
    Denis Gilmore
    Department of Thoracic Surgery, Brigham and Women s Hospital, Boston, Massachusetts, United States
    Thorac Cardiovasc Surg 60:e25-7. 2012
    ..These anomalies cannot be cured and significantly impact quality of life. Multidisciplinary involvement is crucial to maximize symptom relief as surgery to remove lymphatics can be morbid and the disease is usually recurrent...
  44. doi request reprint Ipsilateral intralobar and subphrenic pulmonary sequestration
    Morgan D Schulz
    Division of Thoracic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Ann Thorac Surg 89:2017-9. 2010
    ..In this case, preoperative imaging defined both intralobar and extralobar sequestrations, and after lobectomy for the symptomatic intralobar sequestration, the asymptomatic subdiaphragmatic sequestration is being managed conservatively...
  45. ncbi request reprint Graft produced interleukin-6 functions as a danger signal and promotes rejection after transplantation
    Yurong Liang
    Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA
    Transplantation 84:771-7. 2007
    ..Interleukin (IL)-6 is a pleiotropic cytokine that functions in both the innate and adaptive immune responses. However, the role of IL-6 in allograft rejection remains poorly understood...