- Improved ancestry inference using weights from external reference panelsChia Yen Chen
Department of Epidemiology, Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA
Bioinformatics 29:1399-406. 2013....
- Explicit Modeling of Ancestry Improves Polygenic Risk Scores and BLUP PredictionChia Yen Chen
Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, Massachusetts, United States of America
Genet Epidemiol 39:427-38. 2015..In summary, our results show that explicitly modeling ancestry can be important in both PRS and BLUP prediction...
- Evaluation of polygenic risk scores for predicting breast and prostate cancer riskMitchell J Machiela
Program in Molecular and Genetic Epidemiology, Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Genet Epidemiol 35:506-14. 2011..53 for breast and 0.57 for prostate). We found no significant evidence that PRS using common variants improved risk prediction for BCa and PCa over replicated SNP scores...