Affiliation: Harvard University
- IGF2: epigenetic regulation and role in development and diseaseWendy Chao
Schepens Eye Research Institute, 20 Staniford Street, Boston, MA 02114, United States
Cytokine Growth Factor Rev 19:111-20. 2008..IGF2 protein function will be discussed, along with diseases that involve IGF2 overexpression. Roles for IGF2 in sonic hedgehog (Shh) signaling and angiogenesis will also be explored...
- CTCF, a candidate trans-acting factor for X-inactivation choiceWendy Chao
Howard Hughes Medical Institute, Department of Molecular Biology, Massachusetts General Hospital, Department of Genetics, Harvard Medical School, Boston, MA 02114, USA
Science 295:345-7. 2002..In vitro binding is reduced by CpG methylation and abolished by including non-CpG methylation. We postulate that Tsix and CTCF together establish a regulatable epigenetic switch for X-inactivation...