Ciprian Catana

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc MRI-assisted PET motion correction for neurologic studies in an integrated MR-PET scanner
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Nucl Med 52:154-61. 2011
  2. pmc Motion correction options in PET/MRI
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA Electronic address
    Semin Nucl Med 45:212-23. 2015
  3. pmc PET and MR imaging: the odd couple or a match made in heaven?
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA
    J Nucl Med 54:815-24. 2013
  4. pmc PET/MRI for neurologic applications
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Nucl Med 53:1916-25. 2012
  5. pmc Toward implementing an MRI-based PET attenuation-correction method for neurologic studies on the MR-PET brain prototype
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Nucl Med 51:1431-8. 2010
  6. pmc Simultaneous in vivo positron emission tomography and magnetic resonance imaging
    Ciprian Catana
    Department of Biomedical Engineering, University of California, Genome and Biomedical Sciences Facility, 451 East Health Sciences Drive, Davis, CA 95616, USA
    Proc Natl Acad Sci U S A 105:3705-10. 2008
  7. pmc Multisite Thrombus Imaging and Fibrin Content Estimation With a Single Whole-Body PET Scan in Rats
    Francesco Blasi
    From the Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown F B, B L O, T A R, N J R, D I G, C C, P C Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia P C N, D P C and Institute for Innovation in Imaging, Massachusetts General Hospital, Boston P C
    Arterioscler Thromb Vasc Biol 35:2114-21. 2015
  8. pmc Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI
    Christin Y Sander
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 110:11169-74. 2013
  9. ncbi request reprint Simultaneous acquisition of multislice PET and MR images: initial results with a MR-compatible PET scanner
    Ciprian Catana
    Department of Biomedical Engineering, University of California Davis, Davis, CA 95616, USA
    J Nucl Med 47:1968-76. 2006
  10. pmc Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis
    Mohamad J Alshikho
    From A A Martinos Center for Biomedical Imaging, Department of Radiology M J A, N R Z, M L L, D B C, D I G, C C, B R R, J M H, Neurological Clinical Research Institute, Department of Neurology M J A, P C, J E Y, M E C, N A, and Department of Anesthesiology O A, Massachusetts General Hospital, Harvard Medical School, Charlestown
    Neurology 87:2554-2561. 2016

Collaborators

Detail Information

Publications41

  1. pmc MRI-assisted PET motion correction for neurologic studies in an integrated MR-PET scanner
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Nucl Med 52:154-61. 2011
    ..In this work, a novel algorithm for data processing and rigid-body motion correction (MC) for the MRI-compatible BrainPET prototype scanner is described, and proof-of-principle phantom and human studies are presented...
  2. pmc Motion correction options in PET/MRI
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA Electronic address
    Semin Nucl Med 45:212-23. 2015
    ....
  3. pmc PET and MR imaging: the odd couple or a match made in heaven?
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA
    J Nucl Med 54:815-24. 2013
    ..These examples range from studies that might immediately benefit from PET/MR to more advanced applications on which future development might have an even broader impact...
  4. pmc PET/MRI for neurologic applications
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    J Nucl Med 53:1916-25. 2012
    ..On the MRI side, we present how improved PET quantification can be used to validate several MRI techniques. Finally, we describe promising research, translational, and clinical applications that can benefit from these advanced tools...
  5. pmc Toward implementing an MRI-based PET attenuation-correction method for neurologic studies on the MR-PET brain prototype
    Ciprian Catana
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Nucl Med 51:1431-8. 2010
    ....
  6. pmc Simultaneous in vivo positron emission tomography and magnetic resonance imaging
    Ciprian Catana
    Department of Biomedical Engineering, University of California, Genome and Biomedical Sciences Facility, 451 East Health Sciences Drive, Davis, CA 95616, USA
    Proc Natl Acad Sci U S A 105:3705-10. 2008
    ..In vivo simultaneous PET and MRI studies were performed in mice. Proof-of-principle in vivo MR spectroscopy and functional MRI experiments were also demonstrated with the combined scanner...
  7. pmc Multisite Thrombus Imaging and Fibrin Content Estimation With a Single Whole-Body PET Scan in Rats
    Francesco Blasi
    From the Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown F B, B L O, T A R, N J R, D I G, C C, P C Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia P C N, D P C and Institute for Innovation in Imaging, Massachusetts General Hospital, Boston P C
    Arterioscler Thromb Vasc Biol 35:2114-21. 2015
    ..Therefore, our goal was to test whether positron emission tomography (PET) with the fibrin-binding probe (64)Cu-FBP8 allows multisite thrombus detection and fibrin content estimation...
  8. pmc Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI
    Christin Y Sander
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 110:11169-74. 2013
    ..Overall, these data demonstrate the utility of simultaneous PET/fMRI for investigations of neurovascular coupling that correlate neurochemistry with hemodynamic changes in vivo for any receptor system with an available PET tracer. ..
  9. ncbi request reprint Simultaneous acquisition of multislice PET and MR images: initial results with a MR-compatible PET scanner
    Ciprian Catana
    Department of Biomedical Engineering, University of California Davis, Davis, CA 95616, USA
    J Nucl Med 47:1968-76. 2006
    ..We have designed and built a MR-compatible PET scanner based on avalanche photodiode technology that allows simultaneous acquisition of PET and MR images in small animals...
  10. pmc Glial activation colocalizes with structural abnormalities in amyotrophic lateral sclerosis
    Mohamad J Alshikho
    From A A Martinos Center for Biomedical Imaging, Department of Radiology M J A, N R Z, M L L, D B C, D I G, C C, B R R, J M H, Neurological Clinical Research Institute, Department of Neurology M J A, P C, J E Y, M E C, N A, and Department of Anesthesiology O A, Massachusetts General Hospital, Harvard Medical School, Charlestown
    Neurology 87:2554-2561. 2016
    ..In this cross-sectional study, we aimed to evaluate brain structural abnormalities in relation to glial activation in the same cohort of participants...
  11. pmc Effects of ferumoxytol on quantitative PET measurements in simultaneous PET/MR whole-body imaging: a pilot study in a baboon model
    Ronald Jh Borra
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13th Street, Suite 2301, Charlestown, MA, 02129, USA
    EJNMMI Phys 2:6. 2015
    ....
  12. pmc Disruption of thalamic functional connectivity is a neural correlate of dexmedetomidine-induced unconsciousness
    Oluwaseun Akeju
    Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States
    elife 3:e04499. 2014
    ..We report that loss of thalamo-cortical functional connectivity is sufficient to produce unconsciousness...
  13. pmc Evidence for brain glial activation in chronic pain patients
    Marco L Loggia
    1 MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA 2 Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02155, USA
    Brain 138:604-15. 2015
    ....
  14. pmc Simultaneous fMRI-PET of the opioidergic pain system in human brain
    Hsiao Ying Wey
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA Electronic address
    Neuroimage 102:275-82. 2014
    ....
  15. pmc Fibrin-targeted PET probes for the detection of thrombi
    Katie L Ciesienski
    A A Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, 149 Thirteenth Street, Suite 2301, Charlestown, Massachusetts 02129, USA
    Mol Pharm 10:1100-10. 2013
    ..FBP1 and FBP2 represent promising new probes for the molecular imaging of thrombi...
  16. pmc Imaging Agonist-Induced D2/D3 Receptor Desensitization and Internalization In Vivo with PET/fMRI
    Christin Y Sander
    A A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA
    Neuropsychopharmacology 41:1427-36. 2016
    ..Overall, these results suggest that simultaneous PET/fMRI enables characterization of dynamic neuroreceptor adaptations in vivo, and may offer a first non-invasive method for assessing receptor desensitization and internalization. ..
  17. pmc Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: assessed with [(11)C]-PBR28
    Nicole R Zürcher
    A A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA
    Neuroimage Clin 7:409-14. 2015
    ..Further studies will determine the role of [(11)C]-PBR28 as a marker of treatments that target neuroinflammation. ..
  18. pmc Dynamic functional imaging of brain glucose utilization using fPET-FDG
    Marjorie Villien
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 100:192-9. 2014
    ..fPET-FDG is a highly complementary technique to MRI and provides a rich new way to observe functional changes in brain metabolism. ..
  19. pmc Influence of the partial volume correction method on (18)F-fluorodeoxyglucose brain kinetic modelling from dynamic PET images reconstructed with resolution model based OSEM
    Spencer L Bowen
    Athinoula A Martinos Center for Biomedical Imaging Bldg 149, Rm 2301, 13th St, Charlestown, MA 02129, USA
    Phys Med Biol 58:7081-106. 2013
    ..The results indicate that the PVC implementation and choice of PSF modelling in the reconstruction can significantly impact model parameters. ..
  20. pmc Serial magnetic resonance spectroscopy reveals a direct metabolic effect of cediranib in glioblastoma
    Heisoog Kim
    Massachusetts Institute of Technology, Department of Nuclear Science and Engineering Health Science and Technology, Cambridge, Massachusetts, USA
    Cancer Res 71:3745-52. 2011
    ..Further study is needed to confirm these findings...
  21. pmc Different partial volume correction methods lead to different conclusions: An (18)F-FDG-PET study of aging
    Douglas N Greve
    Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA Radiology Department, Harvard Medical School, Boston, MA, USA Electronic address
    Neuroimage 132:334-43. 2016
    ..Using the SGTM, significant age-related changes of about 7% per decade were found in frontal and cingulate cortices as well as primary visual and insular cortices. ..
  22. pmc On the accuracy and reproducibility of a novel probabilistic atlas-based generation for calculation of head attenuation maps on integrated PET/MR scanners
    Kevin T Chen
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA
    Eur J Nucl Med Mol Imaging . 2016
    ..Demonstrating that novel MR-based photon attenuation correction methods are both accurate and reproducible is essential prior to using them routinely in research and clinical studies on integrated PET/MR scanners...
  23. pmc A 31-channel MR brain array coil compatible with positron emission tomography
    Christin Y Sander
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA
    Magn Reson Med 73:2363-75. 2015
    ..This constraint is the principal barrier to achieving optimum sensitivity on each modality. Here, we present a 31-channel PET-compatible brain array coil with reduced attenuation but improved MR sensitivity...
  24. pmc Radiation Dosimetry of the Fibrin-Binding Probe ⁶⁴Cu-FBP8 and Its Feasibility for PET Imaging of Deep Vein Thrombosis and Pulmonary Embolism in Rats
    Francesco Blasi
    Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts
    J Nucl Med 56:1088-93. 2015
    ..To support clinical translation of (64)Cu-FBP8, we performed a human dosimetry estimation using time-dependent biodistribution in rats...
  25. pmc Effect of MRI acoustic noise on cerebral fludeoxyglucose uptake in simultaneous MR-PET imaging
    Daniel B Chonde
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA
    Invest Radiol 48:302-12. 2013
    ..Although particular attention was paid to the primary auditory cortex (PAC), a brain-wide analysis was also performed...
  26. ncbi request reprint Performance test of an LSO-APD detector in a 7-T MRI scanner for simultaneous PET/MRI
    Bernd J Pichler
    Department of Biomedical Engineering, University of California, Davis, USA
    J Nucl Med 47:639-47. 2006
    ..Unlike CT, MRI provides good soft-tissue contrast even without application of contrast agents and, furthermore, does not require ionizing radiation...
  27. pmc Anatomically-aided PET reconstruction using the kernel method
    Will Hutchcroft
    Department of Biomedical Engineering, University of California Davis, Davis, CA, USA
    Phys Med Biol 61:6668-6683. 2016
    ..Additionally the kernel method is applied to a 3D patient data set. The kernel method results in reduced noise at a matched contrast level compared with the conventional ML expectation maximization algorithm...
  28. pmc Noninvasive Assessment of Losartan-Induced Increase in Functional Microvasculature and Drug Delivery in Pancreatic Ductal Adenocarcinoma
    Vidhya Kumar
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA
    Transl Oncol 9:431-437. 2016
    ....
  29. pmc A receptor-based model for dopamine-induced fMRI signal
    Joseph B Mandeville
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA
    Neuroimage 75:46-57. 2013
    ....
  30. pmc Sensitivity of MRI tumor biomarkers to VEGFR inhibitor therapy in an orthotopic mouse glioma model
    Christian T Farrar
    Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America
    PLoS ONE 6:e17228. 2011
    ....
  31. pmc Bimodal thrombus imaging: simultaneous PET/MR imaging with a fibrin-targeted dual PET/MR probe--feasibility study in rat model
    Ritika Uppal
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 Thirteenth Street, Suite 2301, Charlestown, MA 02129, USA
    Radiology 258:812-20. 2011
    ..To image thrombus by using magnetic resonance (MR) imaging and positron emission tomography (PET) simultaneously in a rat arterial thrombus model with a dual PET/MR probe...
  32. pmc Neural correlates of pair-bonding in a monogamous primate
    Karen L Bales
    Department of Psychology, University of California, Davis, CA 95616, USA
    Brain Res 1184:245-53. 2007
    ....
  33. pmc Neuroinflammatory component of gray matter pathology in multiple sclerosis
    Elena Herranz
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Boston, MA
    Ann Neurol 80:776-790. 2016
    ....
  34. pmc Transmission imaging for integrated PET-MR systems
    Spencer L Bowen
    Athinoula A Martinos Center for Biomedical Imaging, Bldg 149, Rm 2301, 13th St, Charlestown, MA 02129, USA
    Phys Med Biol 61:5547-68. 2016
    ....
  35. doi request reprint Hybrid FDG-PET/MR compared to FDG-PET/CT in adult lymphoma patients
    Wendy Atkinson
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129, USA
    Abdom Radiol (NY) 41:1338-48. 2016
    ..The goal of this study is to evaluate the diagnostic performance of simultaneous FDG-PET/MR including diffusion compared to FDG-PET/CT in patients with lymphoma...
  36. pmc Dopamine D1 signaling organizes network dynamics underlying working memory
    Joshua L Roffman
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13th Street, Charlestown, MA 02129, USA
    Sci Adv 2:e1501672. 2016
    ..These findings specifically link cortical dopamine signaling to network crosstalk that redirects cognitive resources to working memory, echoing neuromodulatory effects of D1 signaling on the level of cortical microcircuits. ..
  37. doi request reprint MR Imaging-Guided Attenuation Correction of PET Data in PET/MR Imaging
    David Izquierdo-Garcia
    Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Charlestown 02129, MA, USA Electronic address
    PET Clin 11:129-49. 2016
    ..The main sources of artifacts are presented. Finally, this review discusses the current status of MR-AC approaches for clinical applications. ..
  38. pmc An SPM8-based approach for attenuation correction combining segmentation and nonrigid template formation: application to simultaneous PET/MR brain imaging
    David Izquierdo-Garcia
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts
    J Nucl Med 55:1825-30. 2014
    ....
  39. pmc MRI-based nonrigid motion correction in simultaneous PET/MRI
    Se Young Chun
    Center for Advanced Radiological Sciences, Nuclear Medicine and Molecular Imaging, Radiology Department, Massachusetts General Hospital, Boston, MA 02114, USA
    J Nucl Med 53:1284-91. 2012
    ..This paper presents an approach to respiratory motion correction using simultaneous PET/MRI to demonstrate initial results in phantoms, rabbits, and nonhuman primates and discusses the prospects for clinical application...
  40. ncbi request reprint PET/MR images acquired with a compact MR-compatible PET detector in a 7-T magnet
    Martin S Judenhofer
    Laboratory for Preclinical Imaging and Imaging Technology, Clinic of Radiology, University of Tubingen, Röntgenweg 13, 72076 Tubingen, Germany
    Radiology 244:807-14. 2007
    ..To prospectively use compact avalanche photodiodes instead of photomultiplier tubes to integrate a positron emission tomographic (PET) detector and a 7-T magnetic resonance (MR) imager...
  41. doi request reprint Simultaneous PET-MRI: a new approach for functional and morphological imaging
    Martin S Judenhofer
    Laboratory for Preclinical Imaging and Imaging Technology of the Werner Siemens Foundation, Department of Radiology, Eberhard Karls University of Tubingen, Röntgenweg 13, 72076 Tubingen, Germany
    Nat Med 14:459-65. 2008
    ..Combining fMRI and spectroscopy with PET paves the way for a new perspective in molecular imaging...