Sarah K Bowman

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Multiplexed Illumina sequencing libraries from picogram quantities of DNA
    Sarah K Bowman
    Department of Molecular Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, MA 02114, USA
    BMC Genomics 14:466. 2013
  2. pmc H3K27 modifications define segmental regulatory domains in the Drosophila bithorax complex
    Sarah K Bowman
    Department of Molecular Biology, Massachusetts General Hospital, Boston, United States Department of Genetics, Harvard Medical School, Boston, United States
    elife 3:e02833. 2014
  3. pmc MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
    Jakub Mieczkowski
    Department of Molecular Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Nat Commun 7:11485. 2016
  4. pmc High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation
    Matthew D Simon
    1 Department of Molecular Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA 2 Department of Molecular Biophysics and Biochemistry, and Chemical Biology Institute, Yale University, West Haven, Connecticut 06516, USA 3
    Nature 504:465-9. 2013

Collaborators

Detail Information

Publications4

  1. pmc Multiplexed Illumina sequencing libraries from picogram quantities of DNA
    Sarah K Bowman
    Department of Molecular Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, MA 02114, USA
    BMC Genomics 14:466. 2013
    ..Existing protocols for picogram-scale libraries require concomitant fragmentation of DNA, pre-amplification, or long overnight steps...
  2. pmc H3K27 modifications define segmental regulatory domains in the Drosophila bithorax complex
    Sarah K Bowman
    Department of Molecular Biology, Massachusetts General Hospital, Boston, United States Department of Genetics, Harvard Medical School, Boston, United States
    elife 3:e02833. 2014
    ..These findings provide a molecular definition of the homeotic domains, and implicate precisely positioned H3K27 modifications as a central determinant of segment identity...
  3. pmc MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
    Jakub Mieczkowski
    Department of Molecular Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
    Nat Commun 7:11485. 2016
    ..Moreover, high nucleosome occupancy does not necessarily preclude high accessibility, which reveals novel principles of chromatin regulation...
  4. pmc High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation
    Matthew D Simon
    1 Department of Molecular Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA 2 Department of Molecular Biophysics and Biochemistry, and Chemical Biology Institute, Yale University, West Haven, Connecticut 06516, USA 3
    Nature 504:465-9. 2013
    ..We conclude that Xist spreading takes distinct stage-specific forms. During initial establishment, Xist follows a two-step mechanism, but during maintenance, Xist spreads rapidly to both gene-rich and gene-poor regions. ..