Andre Bernards

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Of flies and men--studying human disease in Drosophila
    A Bernards
    Massachusetts General Hospital Cancer Center, Building 149, 13th Street, Charlestown, Massachusetts 02129, USA
    Curr Opin Genet Dev 11:274-8. 2001
  2. ncbi request reprint GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila
    Andre Bernards
    Massachusetts General Hospital Cancer Center, Building 149, 13th Street, Charlestown, MA 02129 2000, USA
    Biochim Biophys Acta 1603:47-82. 2003
  3. ncbi request reprint GAPs in growth factor signalling
    Andre Bernards
    Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA
    Growth Factors 23:143-9. 2005
  4. pmc Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-Activating Protein activity in larval neurons
    James A Walker
    Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Genes Dev 20:3311-23. 2006
  5. ncbi request reprint Ras superfamily and interacting proteins database
    Andre Bernards
    Massachusetts General Hospital, Center for Cancer Research, Charlestown, Massachusetts, USA
    Methods Enzymol 407:1-9. 2006
  6. ncbi request reprint GEFs in growth factor signaling
    Andre Bernards
    Harvard Medical School and Massachusetts General Hospital, Center for Cancer Research, Charlestown, MA 02129, USA
    Growth Factors 25:355-61. 2007
  7. ncbi request reprint GAP control: regulating the regulators of small GTPases
    Andre Bernards
    MGH Cancer Center and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA
    Trends Cell Biol 14:377-85. 2004

Research Grants

Collaborators

  • James A Walker
  • Dongyun Wu
  • Iswar K Hariharan
  • Suzanne Brill
  • Glenn S Cowley
  • Anna V Tchoudakova
  • Peter T McKenney

Detail Information

Publications7

  1. ncbi request reprint Of flies and men--studying human disease in Drosophila
    A Bernards
    Massachusetts General Hospital Cancer Center, Building 149, 13th Street, Charlestown, Massachusetts 02129, USA
    Curr Opin Genet Dev 11:274-8. 2001
    ..Conventional Drosophila genetics is being used increasingly to place human disease genes of unknown function in the context of functional pathways...
  2. ncbi request reprint GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila
    Andre Bernards
    Massachusetts General Hospital Cancer Center, Building 149, 13th Street, Charlestown, MA 02129 2000, USA
    Biochim Biophys Acta 1603:47-82. 2003
    ....
  3. ncbi request reprint GAPs in growth factor signalling
    Andre Bernards
    Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA
    Growth Factors 23:143-9. 2005
    ..Here, some of these mechanisms of GAP regulation in the context of signaling responses to growth factors are reviewed...
  4. pmc Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-Activating Protein activity in larval neurons
    James A Walker
    Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Genes Dev 20:3311-23. 2006
    ....
  5. ncbi request reprint Ras superfamily and interacting proteins database
    Andre Bernards
    Massachusetts General Hospital, Center for Cancer Research, Charlestown, Massachusetts, USA
    Methods Enzymol 407:1-9. 2006
    ..A database was compiled to provide easy access to this information. This database also includes information on approximately 360 putative Ras superfamily effector proteins and may be a useful tool for those interested in GTPase biology...
  6. ncbi request reprint GEFs in growth factor signaling
    Andre Bernards
    Harvard Medical School and Massachusetts General Hospital, Center for Cancer Research, Charlestown, MA 02129, USA
    Growth Factors 25:355-61. 2007
    ..In this companion review, we highlight recent findings relating to the regulation of another major class of Ras superfamily regulatory proteins, the guanine nucleotide exchange factors...
  7. ncbi request reprint GAP control: regulating the regulators of small GTPases
    Andre Bernards
    MGH Cancer Center and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA
    Trends Cell Biol 14:377-85. 2004
    ..So far, findings suggest that GAP activity is regulated by several mechanisms, including protein-protein interactions, phospholipid interactions, phosphorylation, subcellular translocation and proteolytic degradation...

Research Grants1

  1. ANALYSIS OF NEUROFIBROMATOSIS TYPE 1 GENE FUNCTION
    Andre Bernards; Fiscal Year: 2003
    ..These studies will help us understand the normal function of the NF1 gene in vivo and will contribute to our understanding of the diverse manifestations of the disease process. ..