Evan Appelbaum

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Intermediate-signal-intensity late gadolinium enhancement predicts ventricular tachyarrhythmias in patients with hypertrophic cardiomyopathy
    Evan Appelbaum
    PERFUSE Core Laboratory and Data Coordinating Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Circ Cardiovasc Imaging 5:78-85. 2012
  2. doi request reprint Science to practice: can the combination of resting first-pass myocardial perfusion and late gadolinium-enhanced cardiovascular MR imaging help identify myocardial infarction resulting from coronary microembolization?
    Evan Appelbaum
    Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, RW 453 Boston, MA 02215, USA
    Radiology 250:609-11. 2009
  3. doi request reprint Mitral valve abnormalities identified by cardiovascular magnetic resonance represent a primary phenotypic expression of hypertrophic cardiomyopathy
    Martin S Maron
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, No 70, 800 Washington St, Boston, MA 02111, USA
    Circulation 124:40-7. 2011
  4. doi request reprint Association of Thrombolysis in Myocardial Infarction Myocardial Perfusion Grade with cardiovascular magnetic resonance measures of infarct architecture after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
    Evan Appelbaum
    Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Am Heart J 158:84-91. 2009
  5. doi request reprint Significance of false negative electrocardiograms in preparticipation screening of athletes for hypertrophic cardiomyopathy
    Ethan J Rowin
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 110:1027-32. 2012
  6. doi request reprint Vitamin D reduces left atrial volume in patients with left ventricular hypertrophy and chronic kidney disease
    Hector Tamez
    Department of Medicine, Division of Nephrology, Massachusetts General Hospital, Boston, USA
    Am Heart J 164:902-9.e2. 2012
  7. doi request reprint Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension
    Anne Catherine Pouleur
    Brigham and Women s Hospital, Boston, MA 02115, USA
    J Renin Angiotensin Aldosterone Syst 12:483-90. 2011
  8. doi request reprint Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: the PRIMO randomized controlled trial
    Ravi Thadhani
    Division of Nephrology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    JAMA 307:674-84. 2012
  9. doi request reprint Clinical profile and significance of delayed enhancement in hypertrophic cardiomyopathy
    Martin S Maron
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Circ Heart Fail 1:184-91. 2008
  10. doi request reprint Prevalence and clinical profile of myocardial crypts in hypertrophic cardiomyopathy
    Martin S Maron
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, MA 02111, USA
    Circ Cardiovasc Imaging 5:441-7. 2012

Detail Information

Publications26

  1. doi request reprint Intermediate-signal-intensity late gadolinium enhancement predicts ventricular tachyarrhythmias in patients with hypertrophic cardiomyopathy
    Evan Appelbaum
    PERFUSE Core Laboratory and Data Coordinating Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Circ Cardiovasc Imaging 5:78-85. 2012
    ....
  2. doi request reprint Science to practice: can the combination of resting first-pass myocardial perfusion and late gadolinium-enhanced cardiovascular MR imaging help identify myocardial infarction resulting from coronary microembolization?
    Evan Appelbaum
    Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, RW 453 Boston, MA 02215, USA
    Radiology 250:609-11. 2009
    ..The degree of left ventricular (LV) systolic dysfunction did not correlate with the quantity of myonecrosis...
  3. doi request reprint Mitral valve abnormalities identified by cardiovascular magnetic resonance represent a primary phenotypic expression of hypertrophic cardiomyopathy
    Martin S Maron
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, No 70, 800 Washington St, Boston, MA 02111, USA
    Circulation 124:40-7. 2011
    ..Therefore, we applied cardiovascular magnetic resonance to characterize mitral valve morphology in a large HCM cohort...
  4. doi request reprint Association of Thrombolysis in Myocardial Infarction Myocardial Perfusion Grade with cardiovascular magnetic resonance measures of infarct architecture after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
    Evan Appelbaum
    Division of Cardiovascular Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Am Heart J 158:84-91. 2009
    ....
  5. doi request reprint Significance of false negative electrocardiograms in preparticipation screening of athletes for hypertrophic cardiomyopathy
    Ethan J Rowin
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, Massachusetts, USA
    Am J Cardiol 110:1027-32. 2012
    ..In principle, this high false-negative rate of 10% represents an important limitation in applying 12-lead electrocardiography to large, apparently healthy athletic populations for the detection of HC...
  6. doi request reprint Vitamin D reduces left atrial volume in patients with left ventricular hypertrophy and chronic kidney disease
    Hector Tamez
    Department of Medicine, Division of Nephrology, Massachusetts General Hospital, Boston, USA
    Am Heart J 164:902-9.e2. 2012
    ..We assessed the effect of an activated vitamin D analog on left atrial volume index (LAVi) in a post hoc analysis of the PRIMO trial (clinicaltrials.gov: NCT00497146)...
  7. doi request reprint Suppression of aldosterone mediates regression of left ventricular hypertrophy in patients with hypertension
    Anne Catherine Pouleur
    Brigham and Women s Hospital, Boston, MA 02115, USA
    J Renin Angiotensin Aldosterone Syst 12:483-90. 2011
    ..High circulating aldosterone levels stimulate myocardial fibrosis and left ventricular hypertrophy (LVH). However, it is not clear whether suppression of aldosterone directly contributes to LVH regression in hypertensive patients...
  8. doi request reprint Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: the PRIMO randomized controlled trial
    Ravi Thadhani
    Division of Nephrology, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    JAMA 307:674-84. 2012
    ..Vitamin D is associated with decreased cardiovascular-related morbidity and mortality, possibly by modifying cardiac structure and function, yet firm evidence for either remains lacking...
  9. doi request reprint Clinical profile and significance of delayed enhancement in hypertrophic cardiomyopathy
    Martin S Maron
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, Massachusetts 02111, USA
    Circ Heart Fail 1:184-91. 2008
    ..Contrast-enhanced cardiovascular magnetic resonance with delayed enhancement (DE) can provide in vivo assessment of myocardial fibrosis. However, the clinical significance of DE in hypertrophic cardiomyopathy (HCM) remains unresolved...
  10. doi request reprint Prevalence and clinical profile of myocardial crypts in hypertrophic cardiomyopathy
    Martin S Maron
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, MA 02111, USA
    Circ Cardiovasc Imaging 5:441-7. 2012
    ..Therefore, we sought to characterize the prevalence and diagnostic significance of myocardial crypts in HCM patients...
  11. doi request reprint Hypertrophic cardiomyopathy: quantification of late gadolinium enhancement with contrast-enhanced cardiovascular MR imaging
    Caitlin J Harrigan
    PERFUSE Core Laboratories and Data Coordinating Center, Beth Israel Deaconess Medical Center, Harvard Medical School, RW 453 East Campus, 330 Brookline Ave, Boston, MA 02215, USA
    Radiology 258:128-33. 2011
    ..To determine the most reproducible semiautomated gray-scale thresholding technique for quantifying late gadolinium enhancement (LGE) in a large cohort of patients with hypertrophic cardiomyopathy (HCM)...
  12. doi request reprint Association of TIMI myocardial perfusion grade and ST-segment resolution with cardiovascular magnetic resonance measures of microvascular obstruction and infarct size following ST-segment elevation myocardial infarction
    Evan Appelbaum
    Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    J Thromb Thrombolysis 27:123-9. 2009
    ..We hypothesized that myocardial perfusion, as assessed by the Thrombolysis in Myocardial Infarction (TIMI) Myocardial Perfusion Grade (TMPG), would be associated with a CMR metric of MO in this population...
  13. doi request reprint Relation between infarct size in ST-segment elevation myocardial infarction treated successfully by percutaneous coronary intervention and left ventricular ejection fraction three months after the infarct
    Yuri B Pride
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 106:635-40. 2010
    ..For small infarcts there is no significant relation between infarct size and LVEF. Up to 15% of LV myocardial volume may be infarcted before there is any appreciable decrease in LVEF...
  14. doi request reprint Significance of Late Gadolinium Enhancement at Right Ventricular Attachment to Ventricular Septum in Patients With Hypertrophic Cardiomyopathy
    Raymond H Chan
    Division of Cardiology, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada Cardiovascular Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts Electronic address
    Am J Cardiol 116:436-41. 2015
    ..Gadolinium pooling in this region of the left ventricle does not reflect myocyte death and repair with replacement fibrosis or scarring...
  15. doi request reprint Hypertrophic cardiomyopathy phenotype revisited after 50 years with cardiovascular magnetic resonance
    Martin S Maron
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, Massachusetts 02111, USA
    J Am Coll Cardiol 54:220-8. 2009
    ....
  16. pmc Autologous cardiomyotissue implantation promotes myocardial regeneration, decreases infarct size, and improves left ventricular function
    Joanna J Wykrzykowska
    Cardiology Division, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Circulation 123:62-9. 2011
    ..We report a novel technique of implanting whole autologous myocardial tissue from preserved myocardial regions into infarcted regions...
  17. doi request reprint Noncardiac pathology on clinical cardiac magnetic resonance imaging
    Peter G Chan
    Department of Medicine Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    JACC Cardiovasc Imaging 2:980-6. 2009
    ..We sought to determine the prevalence of noncardiac pathology in a large consecutive series of patients referred for clinical cardiac magnetic resonance (CMR) studies...
  18. pmc Diagnostic and prognostic utility of cardiovascular magnetic resonance imaging in light-chain cardiac amyloidosis
    Frederick L Ruberg
    Department of Medicine, Boston University School of Medicine, Massachusetts, USA
    Am J Cardiol 103:544-9. 2009
    ..LGE is strongly correlated with heart failure severity as assessed by BNP...
  19. doi request reprint Significance of papillary muscle abnormalities identified by cardiovascular magnetic resonance in hypertrophic cardiomyopathy
    Caitlin J Harrigan
    PERFUSE Core Laboratory and Data Coordinating Center, Harvard Medical School, Boston, MA, USA
    Am J Cardiol 101:668-73. 2008
    ..The identification of accessory PMs may be useful in planning preoperative strategy...
  20. pmc Volumetric left ventricular ejection fraction is superior to 2-dimensional echocardiography for risk stratification of patients for primary prevention implantable cardioverter-defibrillator implantation
    Hussein Rayatzadeh
    Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Am J Cardiol 111:1175-9. 2013
    ..In conclusion, if confirmed by larger prospective series, volumetric methods such as CMR should be considered a superior "gatekeeper" for the identification of patients likely to benefit from primary prevention ICD implantation...
  21. doi request reprint Prognostic value of quantitative contrast-enhanced cardiovascular magnetic resonance for the evaluation of sudden death risk in patients with hypertrophic cardiomyopathy
    Raymond H Chan
    From the PERFUSE Study Group, Harvard Medical School, Boston, MA R H C, S N H, C M B, W J M, E A Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA R H C, S N H, C M B, W J M, E A Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis, MN B J M, T H, J R L Referral Center for Myocardial Diseases, Azienda Ospedaliera Universitaria Careggi, Florence Italy I O, F C, B T Harvard Clinical Research Institute and Boston University Biostatistics, Boston, MA M J P Ospedale Sant Andrea Universita La Sapienza, Rome, Italy G E A, C N D C, C A Division of Cardiology, Toronto General Hospital, University Health Network, University of Toronto, Toronto, ON, Canada C G, A M C, Denmark
    Circulation 130:484-95. 2014
    ....
  22. doi request reprint Relation between myocardial infarct size and ventricular tachyarrhythmia among patients with preserved left ventricular ejection fraction following fibrinolytic therapy for ST-segment elevation myocardial infarction
    Yuri B Pride
    Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 104:475-9. 2009
    ....
  23. doi request reprint Effect of the direct Renin inhibitor aliskiren, the Angiotensin receptor blocker losartan, or both on left ventricular mass in patients with hypertension and left ventricular hypertrophy
    Scott D Solomon
    Cardiovascular Division, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    Circulation 119:530-7. 2009
    ..We compared the effect of aliskiren, the first orally active direct renin inhibitor, the angiotensin-receptor blocker losartan, and their combination on the reduction of LV mass in hypertensive patients...
  24. ncbi request reprint Skin-derived microorgan autotransplantation as a novel approach for therapeutic angiogenesis
    Pierre Voisine
    Angiogenesis Research Center and Interventional Cardiology Section, Division of Cardiology, BIDMC Harvard Medical School, 330 Brookline Ave, Boston, MA 02215, USA
    Am J Physiol Heart Circ Physiol 294:H213-9. 2008
    ..Autotransplantation of SMOs constitutes a novel approach for safe and effective therapeutic angiogenesis with improvement in perfusion, normalization of microvascular reactivity, and increased expression of VEGF and CD31...
  25. doi request reprint Vitamin D receptor activation and left ventricular hypertrophy in advanced kidney disease
    Ravi Thadhani
    Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, USA
    Am J Nephrol 33:139-49. 2011
    ..In chronic kidney disease (CKD), left ventricular hypertrophy (LVH) is prevalent and is associated with increased cardiovascular morbidity and mortality. Vitamin D receptor (VDR) activation attenuates LVH progression in animal models...
  26. ncbi request reprint Coronary magnetic resonance imaging
    Warren J Manning
    Departments of Medicine and Radiology, Cardiovascular Division, Harvard Thorndike Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Cardiol Clin 25:141-70, vi. 2007
    ..It concludes with a brief discussion of the advantages/disadvantages and clinical results comparing coronary MRI with multidetector CT (MDCT) coronary angiography...