Eduardo L Abreu
Affiliation: Harvard University
- Storage conditions do not have detrimental effect on allograft collagen or scaffold performanceE L Abreu
Department of Orthopaedic Surgery, Children s Hospital of Boston, 300 Longwood Ave, Enders 1022, Boston, MA 02115, USA
Cell Tissue Bank 10:333-40. 2009..In conclusion, this study suggests that freezing or refrigeration for 1 week does not appear to have any detrimental effect on the mechanical properties and biologic performance of the collagen within allografts...
- Collagen density significantly affects the functional properties of an engineered provisional scaffoldEduardo L Abreu
Department of Orthopaedic Surgery, Children s Hospital of Boston, Boston, MA 02115, USA
J Biomed Mater Res A 93:150-7. 2010..These studies suggest that the collagen density may be able to significantly influence the function of collagen-platelet hydrogels used as substitute provisional scaffolds...
- Platelets, but not erythrocytes, significantly affect cytokine release and scaffold contraction in a provisional scaffold modelMay Jacobson
CBR Institute for Biomedical Research, Harvard Medical School, Boston, Massachusetts, USA
Wound Repair Regen 16:370-8. 2008..Therefore, while platelets may be an important regulator of repair processes after injury, it is less likely that erythrocytes have a similar function...
- Effect of altered mechanical load conditions on the structure and function of cultured tendon fasciclesEduardo L Abreu
Department of Orthopaedic Surgery, Children s Hospital of Boston, 300 Longwood Avenue, Enders 1022, Boston, Massachusetts 02115, USA
J Orthop Res 26:364-73. 2008..Together these results suggest a role for GAG but not collagen or water in the elastic and viscoelastic changes measured in tendon fascicles cultured for 1 week under altered load conditions...