Harvard University

Summary

Organization: Harvard University
Country: USA

Top Publications

  1. pmc Use of nonsteroidal antiinflammatory agents and incidence of ovarian cancer in 2 large prospective cohorts
    Simone P Pinheiro
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Am J Epidemiol 169:1378-87. 2009
  2. doi Western blot analysis of adhesive interactions under fluid shear conditions: the blot rolling assay
    Robert Sackstein
    Department of Dermatology and Medicine, Brigham and Women s Hospital, 77 Avenue Louis Pasteur, Mailstop HIM, Room 671, Boston, MA, 02115, USA
    Methods Mol Biol 536:343-54. 2009
  3. doi Distribution of fiducial registration error in rigid-body point-based registration
    Mehdi Hedjazi Moghari
    Harvard Medical School, Boston, MA 02215, USA
    IEEE Trans Med Imaging 28:1791-801. 2009
  4. doi "Complementing" toll signaling
    Jonathan C Kagan
    Division of Gastroenterology and Harvard Medical School, Department of Pediatrics, Children s Hospital Boston, Boston, MA 02115, USA
    Sci Signal 3:pe15. 2010
  5. doi Cultivating quality: reducing surgical site infections in children undergoing cardiac surgery
    Patricia Galvin
    Children s Hospital, Boston, MA, USA
    Am J Nurs 109:49-55. 2009
  6. doi Technical advances of interventional fluoroscopy and flat panel image receptor
    Pei Jan Paul Lin
    Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Health Phys 95:650-7. 2008
  7. pmc Reproducibility and accuracy of quantitative myocardial blood flow assessment with (82)Rb PET: comparison with (13)N-ammonia PET
    Georges El Fakhri
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Nucl Med 50:1062-71. 2009
  8. pmc Prospective study of prostate tumor angiogenesis and cancer-specific mortality in the health professionals follow-up study
    Lorelei A Mucci
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 27:5627-33. 2009
  9. doi Swine-origin influenza a (H1N1) viral infection in children: initial chest radiographic findings
    Edward Y Lee
    Departments of Radiology, Medicine, Pulmonary Division, Laboratory Medicine, Infectious Diseases Diagnostic Laboratory, and Anesthesia and Surgery, Children s Hospital Boston and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA
    Radiology 254:934-41. 2010
  10. pmc Long-term results of Dana-Farber Cancer Institute ALL Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1985-2000)
    L B Silverman
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Leukemia 24:320-34. 2010

Detail Information

Publications62

  1. pmc Use of nonsteroidal antiinflammatory agents and incidence of ovarian cancer in 2 large prospective cohorts
    Simone P Pinheiro
    Department of Medicine, Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Am J Epidemiol 169:1378-87. 2009
    ..In this large prospective study, the authors found no compelling evidence to support an association between regular use of aspirin, nonaspirin NSAIDs, or acetaminophen and ovarian cancer incidence...
  2. doi Western blot analysis of adhesive interactions under fluid shear conditions: the blot rolling assay
    Robert Sackstein
    Department of Dermatology and Medicine, Brigham and Women s Hospital, 77 Avenue Louis Pasteur, Mailstop HIM, Room 671, Boston, MA, 02115, USA
    Methods Mol Biol 536:343-54. 2009
    ..This method thus allows for the identification, within a complex mixture and without prior isolation or purification, of both known and previously uncharacterized adhesion molecules operational under dynamic conditions...
  3. doi Distribution of fiducial registration error in rigid-body point-based registration
    Mehdi Hedjazi Moghari
    Harvard Medical School, Boston, MA 02215, USA
    IEEE Trans Med Imaging 28:1791-801. 2009
    ..The solution uses maximum likelihood estimation to calculate the probability density function of registration error at each fiducial point. Extensive numerical simulations are performed to validated the proposed solution...
  4. doi "Complementing" toll signaling
    Jonathan C Kagan
    Division of Gastroenterology and Harvard Medical School, Department of Pediatrics, Children s Hospital Boston, Boston, MA 02115, USA
    Sci Signal 3:pe15. 2010
    ..A new study attempts to model such conditions in vitro and reveals that when macrophages encounter bacteria, two signal transduction pathways interact in a way that profoundly alters the cellular response to infection...
  5. doi Cultivating quality: reducing surgical site infections in children undergoing cardiac surgery
    Patricia Galvin
    Children s Hospital, Boston, MA, USA
    Am J Nurs 109:49-55. 2009
    ..Based on what they learned, the nurses were able to recommend, implement, and evaluate a practice change. This has resulted in reduced SSI rates and improved patient outcomes...
  6. doi Technical advances of interventional fluoroscopy and flat panel image receptor
    Pei Jan Paul Lin
    Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Health Phys 95:650-7. 2008
    ..Finally, rotational angiography with computed tomography (CT) and three dimensional (3-D) images utilizing flat panel technology will be reviewed as they pertain to diagnostic imaging in cardiovascular disease...
  7. pmc Reproducibility and accuracy of quantitative myocardial blood flow assessment with (82)Rb PET: comparison with (13)N-ammonia PET
    Georges El Fakhri
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Nucl Med 50:1062-71. 2009
    ....
  8. pmc Prospective study of prostate tumor angiogenesis and cancer-specific mortality in the health professionals follow-up study
    Lorelei A Mucci
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 27:5627-33. 2009
    ..We examined whether microvessel morphology contributes to the considerable biologic heterogeneity of prostate cancer...
  9. doi Swine-origin influenza a (H1N1) viral infection in children: initial chest radiographic findings
    Edward Y Lee
    Departments of Radiology, Medicine, Pulmonary Division, Laboratory Medicine, Infectious Diseases Diagnostic Laboratory, and Anesthesia and Surgery, Children s Hospital Boston and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA
    Radiology 254:934-41. 2010
    ..c) rsna, 2009...
  10. pmc Long-term results of Dana-Farber Cancer Institute ALL Consortium protocols for children with newly diagnosed acute lymphoblastic leukemia (1985-2000)
    L B Silverman
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Leukemia 24:320-34. 2010
    ..Current studies continue to focus on improving efficacy while minimizing acute and late toxicities...
  11. ncbi Not all neuropathy in diabetes is of diabetic etiology: differential diagnosis of diabetic neuropathy
    Roy Freeman
    Autonomic and Peripheral Nerve Laboratory, Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Curr Diab Rep 9:423-31. 2009
    ..Prospective studies to investigate the prevalence of other disorders that might be responsible for a peripheral neuropathy in individuals with diabetes are warranted...
  12. pmc Progression through the RNA polymerase II CTD cycle
    Stephen Buratowski
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 36:541-6. 2009
    ..Recent papers help to explain how the changes in CTD phosphorylation pattern are linked to the progression from initiation through elongation to termination...
  13. pmc Tumor-derived tissue factor-bearing microparticles are associated with venous thromboembolic events in malignancy
    Jeffrey I Zwicker
    Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Clin Cancer Res 15:6830-40. 2009
    ..We evaluated the hypothesis that tumor-derived tissue factor-bearing microparticles in plasma contribute to cancer-associated thrombosis...
  14. pmc Synthetic lethality: a framework for the development of wiser cancer therapeutics
    William G Kaelin
    Howard Hughes Medical Institute, Dana Farber Cancer Institute and Brigham and Women s Hospital, 44 Binney St, Boston, MA 02115, USA
    Genome Med 1:99. 2009
    ..These approaches will hopefully facilitate the discovery of safer, more efficacious anticancer drugs that exploit vulnerabilities that are unique to cancer cells by virtue of the mutations they have accrued during tumor progression...
  15. pmc Heart rate, autonomic markers, and cardiac mortality
    Richard L Verrier
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Heart Rhythm 6:S68-75. 2009
    ..of these parameters? (3) What mechanisms are responsible for the cardiovascular pathology associated with elevated heart rates? (4) Does reducing heart rate independent of effects on other factors protect against cardiovascular events?..
  16. pmc Mechanics of dynamic needle insertion into a biological material
    Mohsen Mahvash
    Mechanical Engineering, Boston University, Boston, MA 02215, USA
    IEEE Trans Biomed Eng 57:934-43. 2010
    ..Experiments confirm the analytical predictions with multilayered porcine cardiac tissue...
  17. pmc Inconsistency between peri-saccadic mislocalization and compression: evidence for separate "what" and "where" visual systems
    Gang Luo
    Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School, Boston, USA
    J Vis 10:32. 2010
    ....
  18. pmc High throughput transmission optical projection tomography using low cost graphics processing unit
    Claudio Vinegoni
    Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA
    Opt Express 17:22320-32. 2009
    ..By implementing the GPU we have obtained a 300 fold performance enhancement in comparison to a CPU workstation implementation. This enables to obtain on-the-fly reconstructions enabling for high throughput imaging...
  19. pmc Phosphorylation-mediated negative regulation of RIG-I antiviral activity
    Michaela U Gack
    Department of Microbiology and Molecular Genetics, New England Primate Research Center, Harvard Medical School, One Pine Hill Drive, Box 9102, Southborough, MA 01772 9102, USA
    J Virol 84:3220-9. 2010
    ..While Thr-170 phosphorylation keeps RIG-I latent, Lys-172 ubiquitination enables RIG-I to form a stable complex with MAVS, thereby inducing IFN signal transduction...
  20. doi Parental decision making about the HPV vaccine
    Jennifer D Allen
    Dana Farber Cancer Institute, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:2187-98. 2010
    ..Prophylactic human papillomavirus (HPV) vaccines are available, but uptake is suboptimal. Information on factors influencing parental decisions regarding vaccination will facilitate the development of successful interventions...
  21. doi Value-based cleft lip-cleft palate care: a progress report
    Megan M Abbott
    Department of Plastic and Oral Surgery, Children s Hospital, Boston, Mass 02115, USA
    Plast Reconstr Surg 126:1020-5. 2010
    ..In addition, patients have a right to understand the value they receive from their care providers...
  22. pmc Recent clinical trials of acupuncture in the West: responses from the practitioners
    Ted J Kaptchuk
    Harvard Medical School, Boston, MA 02215, USA
    Chin J Integr Med 16:197-203. 2010
    ..The paper also looks at recent neuroimaging experiments on acupuncture that may point to some worthwhile new avenues of investigation. Finally, the Euro-American health care policy consequences of these recent RCTs are discussed...
  23. pmc Columnar cell lesions and subsequent breast cancer risk: a nested case-control study
    Sarah A Aroner
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res 12:R61. 2010
    ..However, the risk of subsequent breast cancer associated with the presence of CCL in a benign breast biopsy is poorly understood...
  24. pmc Polymorphisms in the superoxide dismutase-3 gene are associated with emphysema in COPD
    I C Sørheim
    Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    COPD 7:262-8. 2010
    ..In conclusion, polymorphisms in the SOD3 gene were associated with CT emphysema but not COPD susceptibility, highlighting the importance of phenotype definition in COPD genetics studies...
  25. doi Emerging adulthood and the perception of parental depression
    Girija Kaimal
    Temple University College of Education, Ritter Annex 443, 1301 Cecil B Moore Ave, Philadelphia, PA 19122, USA
    Qual Health Res 20:1213-28. 2010
    ..Some respondents with depression in both parents and/or siblings revealed changes in perception toward one parent but no change toward other family members with depression...
  26. doi Morgana/CHP-1 is a novel chaperone able to protect cells from stress
    Wojciech Michowski
    International Institute of Molecular and Cell Biology ul Ks Trojdena 4, 02 109 Warsaw, Poland
    Biochim Biophys Acta 1803:1043-9. 2010
    ....
  27. pmc Validity of self-report of infections in a longitudinal cohort of patients with rheumatoid arthritis differs by source of report and infection severity
    Julia F Simard
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    J Clin Epidemiol 63:1358-62. 2010
    ..We evaluated and compared the validity of patients' and rheumatologists' reports of infection with those confirmed by medical record review...
  28. pmc Developing and evaluating comprehensive HIV infection control strategies: issues and challenges
    Victor DeGruttola
    Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Clin Infect Dis 50:S102-7. 2010
    ....
  29. doi Hybrid myocardial revascularization: an integrated approach to coronary revascularization
    Jeffrey J Popma
    Cardiovascular Division, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Catheter Cardiovasc Interv 75:S28-34. 2010
    ..The advantages and disadvantages of hybrid myocardial revascularization are reviewed in this report...
  30. ncbi Clinging carcinoma: an American perspective
    Stuart J Schnitt
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Semin Diagn Pathol 27:31-6. 2010
    ....
  31. pmc Plasma homocysteine and cysteine and risk of breast cancer in women
    Jennifer Lin
    Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA
    Cancer Res 70:2397-405. 2010
    ..The increased risk of breast cancer associated with high cysteine levels warrants further investigation...
  32. doi Clinical trial: renzapride treatment of women with irritable bowel syndrome and constipation - a double-blind, randomized, placebo-controlled, study
    A J Lembo
    Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center BIDMC, Harvard Medical School, Boston, MA 02215, USA
    Aliment Pharmacol Ther 31:979-90. 2010
    ..Renzapride, a 5-hydroxytryptamine type-4 (5-HT(4)) receptor agonist and 5-HT(3) receptor antagonist, has been proposed as a new treatment of irritable bowel syndrome with constipation (IBS-C)...
  33. pmc Intake of total trans, trans-18:1, and trans-18:2 fatty acids and risk of sudden cardiac death in women
    Stephanie E Chiuve
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am Heart J 158:761-7. 2009
    ....
  34. doi Radiation therapy options for malignant pleural mesothelioma
    Elizabeth H Baldini
    Department of Radiation Oncology, Dana Farber Brigham and Women s Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts 02115, USA
    Semin Thorac Cardiovasc Surg 21:159-63. 2009
    ..New techniques such as helical tomotherapy and/or IMRT with the addition of electrons may also have a role in future treatment. RT can palliate symptoms provided the disease is confined to a tolerable radiation field...
  35. doi Making smart investments in health information technology: core principles
    John D Halamka
    Harvard Medical School and Beth Israel Deaconess Medical Center in Boston, Massachusetts, USA
    Health Aff (Millwood) 28:w385-9. 2009
    ..To ensure wise investment, I suggest guiding principles assembled from the input of hundreds of providers, patients, payers, vendors, government employees, and standards-development organizations...
  36. doi Increased prevalence of left-handedness in hemifacial microsomia
    Gary F Rogers
    Department of Plastic Surgery, Children s Hospital Boston, Harvard Medical School, 300 Longwood Ave, Boston, Massachusetts 02115
    J Craniofac Surg 20:690-4. 2009
    ..11%; P < 0.05). The frequency was higher, 36%, in those with bilateral involvement (P > 0.05). There was no correlation with predominant side or OMENS score. This study confirms that this disorder affects cerebral lateralization...
  37. doi Leukocyte trafficking in primary immunodeficiencies
    Luigi D Notarangelo
    Division of Immunology, Children s Hospital, Harvard Medical School, 1 Blackfan Circle, Boston, MA 02115, USA
    J Leukoc Biol 85:335-43. 2009
    ..Here, we review the mechanisms and consequences of impaired leukocyte trafficking in leukocyte adhesion-deficiency syndromes, Warts-Hypo-gamma-globulinemia-Infections-Myelokathexis syndrome and Wiskott-Aldrich syndrome...
  38. doi Neurophysiological alterations during strategy-based verbal learning in traumatic brain injury
    GARY E STRANGMAN
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Charlestown, USA
    Neurorehabil Neural Repair 23:226-36. 2009
    ..Verbal learning and strategic processing deficits are common sequelae of traumatic brain injury (TBI); however, the neurophysiological mechanisms underlying such deficits remain poorly understood...
  39. pmc High-resolution melting curve analysis of genomic and whole-genome amplified DNA
    Michael H Cho
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
    Clin Chem 54:2055-8. 2008
    ..Few studies have compared the performance of high-resolution DNA melting curve analysis (HRM) in genomic and whole-genome amplified (WGA) DNA...
  40. pmc The development of nicotinic receptors in the human medulla oblongata: inter-relationship with the serotonergic system
    Jhodie R Duncan
    Department of Pathology, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
    Auton Neurosci 144:61-75. 2008
    ..This study indicates parallel dynamic and complex changes in the medullary nicotinic and 5-HT systems throughout early life, i.e., the period of risk for SIDS...
  41. pmc Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis
    Farouc A Jaffer
    MGH CMIR, 149 13th St, Room 5406, Boston, MA 02129, USA
    Circulation 118:1802-9. 2008
    ..To enable intravascular detection of inflammation in atherosclerosis, we developed a near-infrared fluorescence (NIRF) catheter-based strategy to sense cysteine protease activity during vascular catheterization...
  42. pmc Developmental regulation of neuromodulator function in the stomatogastric ganglion of the lobster, Homarus americanus
    Kristina J Rehm
    Volen Center, Brandeis University, Waltham, Massachusetts 02454 9110, USA
    J Neurosci 28:9828-39. 2008
    ..Moreover, neuromodulator responses change during development, perhaps contributing to the maturation of the output from the stomatogastric nervous system...
  43. pmc Japanese-style acupuncture for endometriosis-related pelvic pain in adolescents and young women: results of a randomized sham-controlled trial
    Peter M Wayne
    Harvard Medical School, Osher Research Center, Boston, Massachusetts 02215, USA
    J Pediatr Adolesc Gynecol 21:247-57. 2008
    ....
  44. doi Recent advances in head and neck cancer
    Robert I Haddad
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    N Engl J Med 359:1143-54. 2008
  45. pmc Molecular imaging in cardiovascular magnetic resonance imaging: current perspective and future potential
    David E Sosnovik
    Department of Cardiology, Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA
    Top Magn Reson Imaging 19:59-68. 2008
    ..The application of molecular MRI in diseases of the vasculature and myocardium is then reviewed. The clinical experience to date, as well as the promise and potential impact of molecular MRI, is extensively discussed...
  46. doi An introduction to reading and appraising qualitative research
    Ayelet Kuper
    Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, 2075 Bayview Avenue, Toronto, ON, Canada M4N 3M5
    BMJ 337:a288. 2008
  47. pmc Chipping away at diagnostics for neurodegenerative diseases
    Clemens R Scherzer
    Laboratory for Neurogenomics, Center for Neurologic Diseases, Harvard Medical School and Brigham and Women s Hospital, 65 Landsdowne Street, Suite 307A, Cambridge, MA 02139, USA
    Neurobiol Dis 35:148-56. 2009
    ..Advances in pre-analytical and analytical methods are improving search efficiency and reproducibility and may lead to a pipeline of biomarker candidates suitable for development into future neurologic diagnostics...
  48. pmc Moving towards making social toxins mainstream in children's environmental health
    Rosalind J Wright
    The Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02067, USA
    Curr Opin Pediatr 21:222-9. 2009
    ..Although traditional disciplinary research theory and methods have focused separately on how social and physical environmental factors affect children's health, evolving research underscores important integrated effects...
  49. doi Utilization of an abbreviated diabetes impact management scale to assess change in subjective disability during a trial of pulsatile insulin delivery demonstrates benefit
    Larry A Weinrauch
    Joslin Diabetes Center, Boston, MA 02215, USA
    Metabolism 58:488-91. 2009
    ..0144, 0.0004). Pulsatile intravenous insulin, when added to standard multiple-dose insulin therapy, was demonstrated to improve subjective perception of neurologic disability on repeated use of an abbreviated form of the DIMS...
  50. pmc A cognitive neuroscience hypothesis of mood and depression
    Moshe Bar
    Martinos Center at Massachusetts General Hospital, Harvard Medical School, 149 Thirteenth Street, Charlestown, MA 02129, USA
    Trends Cogn Sci 13:456-63. 2009
    ....
  51. doi The role of body mass index in acute exacerbations of chronic obstructive pulmonary disease
    C L Tsai
    Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    Emerg Med J 26:701-5. 2009
    ..Low body mass index (BMI) is a strong prognostic marker in stable chronic obstructive pulmonary disease (COPD); however, little is known about its role in acute exacerbations of COPD...
  52. pmc Site-specific regulation of cell cycle and DNA repair in post-mitotic GABA cells in schizophrenic versus bipolars
    Francine M Benes
    Program in Structural and Molecular Neuroscience, McLean Hospital, Belmont, MA 02478, USA
    Proc Natl Acad Sci U S A 106:11731-6. 2009
    ....
  53. pmc Accuracy and precision in quantitative fluorescence microscopy
    Jennifer C Waters
    Harvard Medical School, Department of Cell Biology, Boston, MA 02115, USA
    J Cell Biol 185:1135-48. 2009
    ..Here, I focus on the parameters of digital image acquisition that affect the accuracy and precision of quantitative fluorescence microscopy measurements...
  54. ncbi The evolution of carbon monoxide into medicine
    Leo E Otterbein
    Beth Israel Deaconess Medical Center, Transplant Institute, Boston, MA 02215, USA
    Respir Care 54:925-32. 2009
    ..CO's mechanisms of action at the cellular level depend on the disease and the experimental focus, but the one constant is that CO reestablishes homeostasis...
  55. pmc High b-value apparent diffusion-weighted images from CURVE-ball DTI
    Sharon Peled
    Radiology Department, Brigham and Women s Hospital, Boston, Massachusetts, USA
    J Magn Reson Imaging 30:243-8. 2009
    ..To investigate the utility of a proposed clinical diffusion imaging scheme for rapidly generating multiple b-value diffusion contrast in brain magnetic resonance imaging (MRI) with high signal-to-noise ratio (SNR)...
  56. doi Family-directed cognitive adaptation for schizophrenia
    Michelle S Friedman-Yakoobian
    Massachusetts Mental Health Center, 180 Morton Street, Jamaica Plain, MA 02130, USA
    J Clin Psychol 65:854-67. 2009
    ..We conclude with a case example of a family who participated in the program...
  57. pmc A prospective study of familial conflict, psychological stress, and the development of substance use disorders in adolescence
    Margie Skeer
    Department of Society, Human Development, and Health, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Drug Alcohol Depend 104:65-72. 2009
    ..Evidence for this is largely based on cross-sectional studies which have been unable to establish the temporality of this association and investigate underlying pathways...
  58. pmc Weight cycling and mortality among middle-aged or older women
    Alison E Field
    Division of Adolescent Medicine, Department of Medicine, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA, USA
    Arch Intern Med 169:881-6. 2009
    ..Controversy exists about whether weight cycling increases morbidity and mortality...
  59. doi Strategic choices for global energy: constraints from feedbacks in the climate system
    James G Anderson
    Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA
    ChemSusChem 2:369-76. 2009
    ..With ever-rising population numbers and energy demand, what should guide us when transforming our society into one that develops in a sustainable manner?..
  60. doi Current state and future applications of active targeting in malignancies using superparamagnetic iron oxide nanoparticles
    Tina Islam
    Center for Molecular Imaging Research, Charlestown, Massachusetts, USA
    Cancer Biomark 5:99-107. 2009
    ..With the advent of multimodality imaging techniques like targeted nanoparticle-enhanced MRI and near infrared optical fluorescence imaging, the combined advantages of different systems can be exploited...
  61. pmc Validity and reliability of a Fijian translation and adaptation of the Eating Disorder Examination Questionnaire
    Anne E Becker
    Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA
    Int J Eat Disord 43:171-8. 2010
    ..Assessment of disordered eating has uncertain validity across culturally diverse populations. This study evaluated Eating Disorder Examination Questionnaire (EDE-Q) performance in an ethnic Fijian study population...
  62. pmc Intravital imaging of CD8+ T cell function in cancer
    Thorsten R Mempel
    Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA
    Clin Exp Metastasis 26:311-27. 2009
    ....

Research Grants62

  1. Epigenetic Events and Colorectal Cancer Epidemiology
    Shuji Ogino; Fiscal Year: 2010
    ..Through better understanding of epigenetic mechanisms of colorectal cancer development and progression, we can provide a scientific basis for dietary recommendations and help optimize preventive strategies. ..
  2. MOLECULAR EPIDEMIOLOGY OF COLORECTAL CANCER
    Shuji Ogino; Fiscal Year: 2007
    ..Charles Fuchs, a well-established researcher in clinical oncology and epidemiology. At the completion of the projects, I will have gained the experience to become an independent researcher in cancer epidemiology. ..
  3. Determinants and Cardiovascular Consequences of Diabetes in Older Adults
    Kenneth Mukamal; Fiscal Year: 2009
    ....
  4. Quantifying the Value of Value-Based Purchasing
    Ronald Kessler; Fiscal Year: 2006
    ..abstract_text> ..
  5. Risk Factors for Psychopathology in the WHO WMH Surveys
    Ronald Kessler; Fiscal Year: 2006
    ..The unprecedented size and substantive richness of the WMH database will allow important contributions to be made in each of these six areas of investigation. ..
  6. Epidemiology - National Comorbidity Survey Replication
    Ronald Kessler; Fiscal Year: 2007
    ..physical disorders on family burden; and (vi) to analyze the temporal unfolding of multivariate comorbid disorder profiles over the life course. ..
  7. Risk Factors for Psychopathology in the WHO WMH Surveys
    Ronald Kessler; Fiscal Year: 2009
    ..Third, the level of detail in the description of data analysis plans has been substantially expanded in this revised submission in response to reviewer comments. ..
  8. Endothelial Dysfunction, Oxidative Stress and Risk of Peripheral Arterial Disease
    Kenneth Mukamal; Fiscal Year: 2009
    ..Finally, we will examine how a derived dietary antioxidant score, based upon measured oxidative potential of specific foods using the ferric-reducing/antioxidant power method, is related to PAD. ..
  9. Heavy Drinking & Coronary Disease: Acute/Chronic Effects
    Kenneth Mukamal; Fiscal Year: 2006
    ..These results may prove to have important biological, clinical, and public health implications for the care of CHD. ..
  10. MENTAL DISORDERS AS RISK FACTORS FOR SUBSTANCE DISORDERS
    Ronald Kessler; Fiscal Year: 2003
    ....
  11. Endothelial Dysfunction, Oxidative Stress and Risk of Peripheral Arterial Disease
    Kenneth Jay Mukamal; Fiscal Year: 2010
    ..Finally, we will examine how a derived dietary antioxidant score, based upon measured oxidative potential of specific foods using the ferric-reducing/antioxidant power method, is related to PAD. ..
  12. fMRI of Unconscious Affect Processing in Adolescence
    WILLIAM KILLGORE; Fiscal Year: 2002
    ..This knowledge will directly impact the understanding of the neurobiological bases of normal and abnormal emotional processing, and potentially lead to a better understanding of factors leading to emotional dysfunction. ..
  13. Determinants and Cardiovascular Consequences of Diabetes in Older Adults
    Susan J Zieman; Fiscal Year: 2010
    ....
  14. Outreach and Treatment for Depression in the Labor Force
    Ronald Kessler; Fiscal Year: 2005
    ..This is an extremely important opportunity for rapid and widespread dissemination in an area of research where dissemination of positive results has traditionally been a serious problem. ..
  15. Hurricane Katrina Community Advisory Group
    Ronald C Kessler; Fiscal Year: 2010
    ....
  16. Fatty Acids and Heart Failure in the Physicians' Health Study
    Luc Djousse; Fiscal Year: 2009
    ....
  17. Fatty Acids and Heart Failure in the Physicians' Health Study
    Luc Djousse; Fiscal Year: 2010
    ....
  18. Genetic Factors and Cardiovascular Disease
    Luc Djousse; Fiscal Year: 2005
    ..Lastly, we will use data collected on participants of the GENCAC study to evaluate these genetic factors in relation to coronary calcification, a measure of coronary atherosclerosis. ..
  19. Defibrotide for the treatment of severe hepatic veno-cc*
    Paul Richardson; Fiscal Year: 2007
    ..Abstract Not Provided ..
  20. Asthma Disparities: Advancing Multilevel Causal Models
    VENKATA SANKARANARAYANAN; Fiscal Year: 2007
    ..integrative and transdisciplinary approach to these issues, drawing on the rich resources available within Harvard University, including access to community-based study populations as well as to expertise from multiple fields...
  21. MCLEAN STUDY OF ADULT DEVELOPMENT
    Mary C Zanarini; Fiscal Year: 2010
    ..This study will provide patients, their families, and those treating them with crucial information they need to plan for the future. ..
  22. MCLEAN STUDY OF ADULT DEVELOPMENT
    Mary Zanarini; Fiscal Year: 2009
    ..This proposed continuation will result in useful knowledge about the course of borderline psychopathology, with direct implications for patients, their families, and the clinicians treating them. ..
  23. MCLEAN STUDY OF ADULT DEVELOPMENT
    Mary Zanarini; Fiscal Year: 2004
    ..In addition, knowledgeable informants will be interviewed concerning each patient's psychosocial functioning, and medical, work, and school records will be collected and reviewed. ..
  24. Theory and methods for sufficient cause interactions
    Tyler VanderWeele; Fiscal Year: 2010
    ..The research will make important advances to the statistical literature on the concept of interaction and on the implications of measurement error for causal inference. ..
  25. Medicare Part D Plan Generosity & Dual-Eligible Nursing Home Residents
    Haiden A Huskamp; Fiscal Year: 2010
    ....
  26. Effects of Light at Night on Circadian System in Nurses
    Eva Schernhammer; Fiscal Year: 2005
    ....
  27. Economics of Formulary Design and Mental Health Policy
    Haiden Huskamp; Fiscal Year: 2006
    ..Huskamp the training, mentoring, time and resources to develop the skills that will put her in a position to lead independent research on the economics of pharmaceutical treatment for mental illnesses. ..
  28. Clock Genes, Night Work, and Breast Cancer Risk
    Eva Schernhammer; Fiscal Year: 2007
    ..The results from this study could help identify individuals who are more susceptible to night work than others, based on their genetic profile. ..
  29. A Pilot Trial of Oral Melatonin Supplementation in Breast Cancer Survivors
    Eva Schernhammer; Fiscal Year: 2007
    ..This pilot data could lay the groundwork for a large scale trial to assess the chemopreventive potential of melatonin in women, both with and without a personal history of breast cancer. ..
  30. The Interplay Between Sleep, Melatonin, and Mortality in Older Men
    Eva S Schernhammer; Fiscal Year: 2010
    ..We will use existing resources from 2,846 participants of the ongoing MrOS Sleep Study. If successful, our study could lay the groundwork for a melatonin trial for healthy aging in the elderly. ..