Douglas O Sobel

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. ncbi request reprint Characterization of anti-islet cytotoxic human T-cell clones from patients with type 1 diabetes mellitus
    Douglas O Sobel
    Department of Pediatrics, Georgetown University Medical Center, Washington, DC 20007 2197, USA
    Autoimmunity 39:323-32. 2006
  2. doi request reprint Cyclosporin and methotrexate therapy induces remission in type 1 diabetes mellitus
    Douglas O Sobel
    Department of Pediatrics, Georgetown University Medical Center, Washington, DC 20007, USA
    Acta Diabetol 47:243-50. 2010
  3. doi request reprint Interferon-tau inhibits the development of diabetes in NOD mice
    Douglas O Sobel
    Georgetown University Children s Medical Center, NW Washington, DC 20007, USA
    Autoimmunity 41:543-53. 2008
  4. ncbi request reprint Gamma interferon paradoxically inhibits the development of diabetes in the NOD mouse
    Douglas O Sobel
    Georgetown University Medical Center, Division of Pediatric Endocrinology and Metabolism, 3800 Reservoir Road N W, 2 PHC, Washington, DC 20007 2197, USA
    J Autoimmun 19:129-37. 2002
  5. ncbi request reprint Self-efficacy, outcome expectations, and diabetes self-management in adolescents with type 1 diabetes
    Ronald J Iannotti
    Prevention Research Branch, Division of Statistics, Epidemiology and Prevention Research, National Institute of Child Health and Human Development, Bethesda, Maryland, USA
    J Dev Behav Pediatr 27:98-105. 2006
  6. ncbi request reprint Assessing regimen adherence of adolescents with type 1 diabetes
    Ronald J Iannotti
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development National Institutes of Health, 6100 Executive Blvd, 7B05, Bethesda, MD 20892 7510, USA
    Diabetes Care 29:2263-7. 2006
  7. ncbi request reprint Identification of distinct self-management styles of adolescents with type 1 diabetes
    Stefan Schneider
    National Institute of Child Health and Human Development NIH DHHS, 6100 Executive Blvd, Bethesda, MD 20892 7510, USA
    Diabetes Care 30:1107-12. 2007

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Characterization of anti-islet cytotoxic human T-cell clones from patients with type 1 diabetes mellitus
    Douglas O Sobel
    Department of Pediatrics, Georgetown University Medical Center, Washington, DC 20007 2197, USA
    Autoimmunity 39:323-32. 2006
    ..Further, the isolation of hsp60 reactive clone with anti-islet cytotoxic properties suggests that cell mediated immunity against hsp60 may be important in the pathogenesis of diabetes...
  2. doi request reprint Cyclosporin and methotrexate therapy induces remission in type 1 diabetes mellitus
    Douglas O Sobel
    Department of Pediatrics, Georgetown University Medical Center, Washington, DC 20007, USA
    Acta Diabetol 47:243-50. 2010
    ..5, 4.5, 8, and 12 months. Low-dose cyclo and mtx treatment of subjects with new onset T1D can safely induce remission of disease and decrease the amount of required insulin...
  3. doi request reprint Interferon-tau inhibits the development of diabetes in NOD mice
    Douglas O Sobel
    Georgetown University Children s Medical Center, NW Washington, DC 20007, USA
    Autoimmunity 41:543-53. 2008
    ..Due to the lower drug toxicity, IFN-tau could be a better drug candidate than IFN-alpha for experimental clinical trials...
  4. ncbi request reprint Gamma interferon paradoxically inhibits the development of diabetes in the NOD mouse
    Douglas O Sobel
    Georgetown University Medical Center, Division of Pediatric Endocrinology and Metabolism, 3800 Reservoir Road N W, 2 PHC, Washington, DC 20007 2197, USA
    J Autoimmun 19:129-37. 2002
    ..The suppression of Th1 cell related cytokines and/or augmentation of the macrophage cytokine IL-1 may play a role in the diabetes sparing effect of rIFN-gamma...
  5. ncbi request reprint Self-efficacy, outcome expectations, and diabetes self-management in adolescents with type 1 diabetes
    Ronald J Iannotti
    Prevention Research Branch, Division of Statistics, Epidemiology and Prevention Research, National Institute of Child Health and Human Development, Bethesda, Maryland, USA
    J Dev Behav Pediatr 27:98-105. 2006
    ..These brief measures can be used to identify youths at risk of poor diabetes self-management. Interventions targeting self-efficacy may lead to improved diabetes self-management...
  6. ncbi request reprint Assessing regimen adherence of adolescents with type 1 diabetes
    Ronald J Iannotti
    Division of Epidemiology, Statistics, and Prevention Research, National Institute of Child Health and Human Development National Institutes of Health, 6100 Executive Blvd, 7B05, Bethesda, MD 20892 7510, USA
    Diabetes Care 29:2263-7. 2006
    ..The Diabetes Behavior Rating Scale (DBRS) is a self-administered, fixed-choice survey...
  7. ncbi request reprint Identification of distinct self-management styles of adolescents with type 1 diabetes
    Stefan Schneider
    National Institute of Child Health and Human Development NIH DHHS, 6100 Executive Blvd, Bethesda, MD 20892 7510, USA
    Diabetes Care 30:1107-12. 2007
    ..Using a profile-based approach to the assessment of diabetes management, the purpose of this study was to identify and evaluate an empirically derived classification system of distinct self-management styles...