M Freedman

Summary

Affiliation: Georgetown University
Country: USA

Publications

  1. pmc A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    David G Cox
    Program in Molecular and Genetic Epidemiology, Epidemiology Department, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res 8:R54. 2006
  2. ncbi request reprint State-of-the-art screening for lung cancer (part 1): the chest radiograph
    Matthew Freedman
    Lombardi Cancer Center and Imaging Science and Information Systems Research Center, Georgetown University Medical Center, Lombardi Building S150, Box 20057 1465, 3800 Reservoir Road, NW Washington, DC 20057 1465, USA
    Thorac Surg Clin 14:43-52. 2004
  3. ncbi request reprint Improved small volume lung cancer detection with computer-aided detection: database characteristics and imaging of response to breast cancer risk reduction strategies
    Matthew Freedman
    Department of Oncology, Division of Cancer Genetics and Epidemiology, ISIS Imaging Science and Information Systems Research Center, Georgetown University Medical Center, Box 20057 1465, Washington, D C 20057 1465, USA
    Ann N Y Acad Sci 1020:175-89. 2004
  4. ncbi request reprint Reader variability: what we can learn from computer-aided detection experiments
    Matthew Freedman
    Lombardi Cancer Center, Division of Cancer Genetics and Epidemiology, Department of Oncology, Georgetown University Medical Center, Washington, DC 20057, USA
    J Am Coll Radiol 3:446-55. 2006
  5. doi request reprint Heat maps: an aid for data analysis and understanding of ROC CAD experiments
    Matthew T Freedman
    Division of Cancer Genetics and Epidemiology, Department of Oncology, Georgetown University Medical Center, Lombardi Building S150 Office S184A, Washington, DC 20057, USA
    Acad Radiol 15:249-59. 2008
  6. ncbi request reprint Digitized mammography: a clinical trial of postmenopausal women randomly assigned to receive raloxifene, estrogen, or placebo
    M Freedman
    Georgetown University Medical Center, Washington, DC 20007, USA
    J Natl Cancer Inst 93:51-6. 2001
  7. ncbi request reprint Image-guided robotic delivery system for precise placement of therapeutic agents
    K Cleary
    Imaging Science and Information Systems ISIS Center, Radiology Department, Georgetown University Medical Center, Washington, DC 20007, USA
    J Control Release 74:363-8. 2001
  8. ncbi request reprint Acceptability of diagnostic tests for breast cancer
    Wenchi Liang
    Department of Oncology, Georgetown University Medical Center, Georgetown University, Washington, DC 20007, USA
    Breast Cancer Res Treat 79:199-206. 2003
  9. ncbi request reprint Technology improvements for image-guided and minimally invasive spine procedures
    Kevin Cleary
    Imaging Science and Information Systems Center, Department of Radiology, Georgetown University Medical Center, Washington, DC 20007, USA
    IEEE Trans Inf Technol Biomed 6:249-61. 2002
  10. ncbi request reprint Serendipity in diagnostic imaging: magnetic resonance imaging of the breast
    W F Lawrence
    Cancer Clinical and Economic Outcomes Core, Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA
    J Natl Cancer Inst 90:1792-800. 1998

Collaborators

Detail Information

Publications23

  1. pmc A comprehensive analysis of the androgen receptor gene and risk of breast cancer: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    David G Cox
    Program in Molecular and Genetic Epidemiology, Epidemiology Department, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res 8:R54. 2006
    ..Here, we report on the results of a large and comprehensive study of the association between genetic variation in the AR gene and risk of breast cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)...
  2. ncbi request reprint State-of-the-art screening for lung cancer (part 1): the chest radiograph
    Matthew Freedman
    Lombardi Cancer Center and Imaging Science and Information Systems Research Center, Georgetown University Medical Center, Lombardi Building S150, Box 20057 1465, 3800 Reservoir Road, NW Washington, DC 20057 1465, USA
    Thorac Surg Clin 14:43-52. 2004
    ....
  3. ncbi request reprint Improved small volume lung cancer detection with computer-aided detection: database characteristics and imaging of response to breast cancer risk reduction strategies
    Matthew Freedman
    Department of Oncology, Division of Cancer Genetics and Epidemiology, ISIS Imaging Science and Information Systems Research Center, Georgetown University Medical Center, Box 20057 1465, Washington, D C 20057 1465, USA
    Ann N Y Acad Sci 1020:175-89. 2004
    ..Bioinformatics will be an important contributor to this in vivo imaging biomarker development...
  4. ncbi request reprint Reader variability: what we can learn from computer-aided detection experiments
    Matthew Freedman
    Lombardi Cancer Center, Division of Cancer Genetics and Epidemiology, Department of Oncology, Georgetown University Medical Center, Washington, DC 20057, USA
    J Am Coll Radiol 3:446-55. 2006
    ..Computer-aided detection, therefore, decreases intraobserver variability and interobserver variability...
  5. doi request reprint Heat maps: an aid for data analysis and understanding of ROC CAD experiments
    Matthew T Freedman
    Division of Cancer Genetics and Epidemiology, Department of Oncology, Georgetown University Medical Center, Lombardi Building S150 Office S184A, Washington, DC 20057, USA
    Acad Radiol 15:249-59. 2008
    ....
  6. ncbi request reprint Digitized mammography: a clinical trial of postmenopausal women randomly assigned to receive raloxifene, estrogen, or placebo
    M Freedman
    Georgetown University Medical Center, Washington, DC 20007, USA
    J Natl Cancer Inst 93:51-6. 2001
    ..We assessed changes in mammographic density among women receiving placebo, raloxifene, or conjugated equine estrogens in an osteoporosis prevention trial...
  7. ncbi request reprint Image-guided robotic delivery system for precise placement of therapeutic agents
    K Cleary
    Imaging Science and Information Systems ISIS Center, Radiology Department, Georgetown University Medical Center, Washington, DC 20007, USA
    J Control Release 74:363-8. 2001
    ..In future work, we plan to fuse preoperative PET imaging with intraoperative CT to allow functional as well as anatomic image guidance...
  8. ncbi request reprint Acceptability of diagnostic tests for breast cancer
    Wenchi Liang
    Department of Oncology, Georgetown University Medical Center, Georgetown University, Washington, DC 20007, USA
    Breast Cancer Res Treat 79:199-206. 2003
    ..To assess the acceptability of new non-invasive breast cancer diagnostic tests intended to triage women in need of biopsy...
  9. ncbi request reprint Technology improvements for image-guided and minimally invasive spine procedures
    Kevin Cleary
    Imaging Science and Information Systems Center, Department of Radiology, Georgetown University Medical Center, Washington, DC 20007, USA
    IEEE Trans Inf Technol Biomed 6:249-61. 2002
    ....
  10. ncbi request reprint Serendipity in diagnostic imaging: magnetic resonance imaging of the breast
    W F Lawrence
    Cancer Clinical and Economic Outcomes Core, Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA
    J Natl Cancer Inst 90:1792-800. 1998
    ..To understand better whether or not biopsy procedures should be performed to evaluate serendipitous lesions, we estimated the breast cancer risk for women with this type of lesion...
  11. ncbi request reprint A pilot study to establish a clinical model to perform phase II studies of breast cancer chemopreventive agents in women at high risk with biomarkers as surrogate endpoints for activity
    Vered Stearns
    Breast Cancer Program, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA
    Clin Cancer Res 10:8332-40. 2004
    ..We chose tamoxifen to establish proof of principal with a known effective agent...
  12. pmc Nanodelivery of MRI contrast agent enhances sensitivity of detection of lung cancer metastases
    Matthew Freedman
    Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Road NW, Washington, DC 20057 1469, USA
    Acad Radiol 16:627-37. 2009
    ..Therefore, there is a need for enhanced sensitivity/specificity of detection for small lung cancers...
  13. ncbi request reprint Detection of LOH and mitochondrial DNA alterations in ductal lavage and nipple aspirate fluids from hngh-risk patients
    Claudine Isaacs
    Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA
    Breast Cancer Res Treat 84:99-105. 2004
    ..One NAF sample from a BRCA1 patient showed a mtDNA mutation. Our data demonstrates the feasibility of performing molecular studies using the free DNA present in the ductal fluid, while the intact cells can be used for cytologic studies...
  14. ncbi request reprint Reflectance confocal microscopy for characterization of mammary ductal structures and development of neoplasia in genetically engineered mouse models of breast cancer
    Angela Parrish
    Georgetown University, Lombardi Comprehensive Cancer Center, 3970 Reservoir Road NW, Washington, DC 20057, USA
    J Biomed Opt 10:051602. 2005
    ..In summary, reflectance confocal microscopy is a tool that can be used to rapidly and accurately analyze mammary gland structure...
  15. ncbi request reprint Independent versus sequential reading in ROC studies of computer-assist modalities: analysis of components of variance
    Sergey V Beiden
    Center for Devices and Radiological Health, Food and Drug Administration, Rockville, MD 20857, USA
    Acad Radiol 9:1036-43. 2002
    ..In the "independent" mode the readings are separated by about I month; in the "sequential" mode, the computer-assisted reading immediately follows the unassisted reading...
  16. ncbi request reprint Diagnostic procedures after a positive spiral computed tomography lung carcinoma screen
    Paul F Pinsky
    Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Cancer 103:157-63. 2005
    ....
  17. ncbi request reprint Final results of the Lung Screening Study, a randomized feasibility study of spiral CT versus chest X-ray screening for lung cancer
    John K Gohagan
    Division of Cancer Prevention, National Cancer Institute, 6130 Executive Blvd, EPN 3064, Bethesda, MD 20892, USA
    Lung Cancer 47:9-15. 2005
    ..A total of 16 stage III-IV cancers were observed in the LDCT arm versus nine in the CXR arm. The LSS has established the feasibility of a RCT comparing annual spiral CT to chest X-ray for lung cancer screening...
  18. ncbi request reprint Como international conference position statement: lung cancer screening for early diagnosis 5 years after the 1998 Varese conference
    Gary M Strauss
    Division of Medical Oncology, Rhode Island Hospital, Brown Medical School, 593 Eddy St, Providence, RI 02903, USA
    Chest 127:1146-51. 2005
    ..The Como Conference was undertaken to consider the need for a change in the existing recommendations against screening...
  19. ncbi request reprint Abnormalities on chest radiograph reported in subjects in a cancer screening trial
    Paul F Pinsky
    Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Chest 130:688-93. 2006
    ..There is little literature either on the prevalence in the general population of various abnormalities seen on CXRs or on the risks associated with these abnormalities...
  20. pmc Sensitivity of noncommercial computer-aided detection system for mammographic breast cancer detection: pilot clinical trial
    Mark A Helvie
    Department of Radiology, University of Michigan Health Systems, 1500 E Medical Center Dr, TC 2910, Ann Arbor, MI 48109 0326, USA
    Radiology 231:208-14. 2004
    ..To evaluate a noncommercial computer-aided detection (CAD) program for breast cancer detection with screening mammography...
  21. pmc Prevalence of non-cancer-related abnormalities on low-dose spiral computer tomography versus chest radiograph in a screening population
    Paul Pinsky
    Thorax 62:190. 2007
  22. ncbi request reprint Modeling and E-M estimation of haplotype-specific relative risks from genotype data for a case-control study of unrelated individuals
    Daniel O Stram
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Hum Hered 55:179-90. 2003
    ..1]) the differences between the three methods are very small and in particular that the single imputation method may be expected to work extremely well...
  23. ncbi request reprint Sequence variants of estrogen receptor beta and risk of prostate cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Yen Ching Chen
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:1973-81. 2007
    ..Estrogen receptor beta (ESR2) may play a role in modulating prostate carcinogenesis through the regulation of genes related to cell proliferation and apoptosis...