Affiliation: George Washington University
- Distinct polyadenylation landscapes of diverse human tissues revealed by a modified PA-seq strategyTing Ni
National Heart Lung Blood Institute, National Institutes of Health, Genetics and Development Biology Center, 9000 Rockville Pike, Bethesda, MD, 20892, USA
BMC Genomics 14:615. 2013..Polyadenylation is a key regulatory step in eukaryotic gene expression and one of the major contributors of transcriptome diversity. Aberrant polyadenylation often associates with expression defects and leads to human diseases...
- An integrated strategy for identification of both sharp and broad peaks from next-generation sequencing dataWeiqun Peng
Department of Physics, The George Washington University, 725 21st Street NW, Washington, DC 20052, USA
Genome Biol 12:120. 2011..A novel integrative approach has been developed by Lieb and colleagues for analyzing genome-wide datasets of different chromatin-binding factors and epigenetic states that exhibit both sharp and diffuse signals on the genome...