A F Gelb

Summary

Country: USA

Publications

  1. doi request reprint Long-term safety and efficacy of twice-daily aclidinium bromide in patients with COPD
    Arthur F Gelb
    Southern California Clinical Trials, 3650 E South Street, Suite 308, Lakewood, CA 90805, USA Electronic address
    Respir Med 107:1957-65. 2013
  2. doi request reprint Review of exhaled nitric oxide in chronic obstructive pulmonary disease
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA, USA
    J Breath Res 6:047101. 2012
  3. doi request reprint In moderate-to-severe asthma patients monitoring exhaled nitric oxide during exacerbation is not a good predictor of spirometric response to oral corticosteroid
    Arthur F Gelb
    Department of Medicine, Pulmonary Division, Lakewood Regional Medical Center, Lakewood, CA 90712, USA
    J Allergy Clin Immunol 129:1491-8. 2012
  4. ncbi request reprint Unsuspected pseudophysiologic emphysema in chronic persistent asthma
    A F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, University of California, Los Angeles, CA, USA
    Am J Respir Crit Care Med 162:1778-82. 2000
  5. doi request reprint Bronchodilator efficacy of the fixed combination of ipratropium and albuterol compared to albuterol alone in moderate-to-severe persistent asthma
    Arthur F Gelb
    Pulmonary Division, Lakewood Regional Medical Center, Lakewood, CA, USA
    Pulm Pharmacol Ther 21:630-6. 2008
  6. pmc Effect of fluticasone 250 microg/salmeterol 50 microg and montelukast on exhaled nitric oxide in asthmatic patients
    Arthur F Gelb
    Division of Pulmonary Services, Department of Medicine, Lakewood Regional Medical Center, Lakewood, Los Angeles, USA
    Can Respir J 15:193-8. 2008
  7. doi request reprint Tiotropium induced bronchodilation and protection from dynamic hyperinflation is independent of extent of emphysema in COPD
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA, USA
    Pulm Pharmacol Ther 22:237-42. 2009
  8. doi request reprint Role of add-on zileuton on total exhaled, large airway, and small airway/alveolar nitric oxide in moderate-severe persistent adult asthmatics on fluticasone 250 microg/Salmeterol 50 microg
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA 90712, USA
    Pulm Pharmacol Ther 22:516-21. 2009
  9. doi request reprint Central and peripheral airway sites of nitric oxide gas exchange in COPD
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA, USA
    Chest 137:575-84. 2010
  10. doi request reprint Central and peripheral airway/alveolar sites of exhaled nitric oxide in acute asthma
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, and Geffen School of Medicine, University of California at Los Angeles Medical Center, Lakewood, California, USA
    Thorax 65:619-25. 2010

Detail Information

Publications25

  1. doi request reprint Long-term safety and efficacy of twice-daily aclidinium bromide in patients with COPD
    Arthur F Gelb
    Southern California Clinical Trials, 3650 E South Street, Suite 308, Lakewood, CA 90805, USA Electronic address
    Respir Med 107:1957-65. 2013
    ..Aclidinium is a novel, long-acting muscarinic antagonist indicated for maintenance treatment of COPD...
  2. doi request reprint Review of exhaled nitric oxide in chronic obstructive pulmonary disease
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA, USA
    J Breath Res 6:047101. 2012
    ....
  3. doi request reprint In moderate-to-severe asthma patients monitoring exhaled nitric oxide during exacerbation is not a good predictor of spirometric response to oral corticosteroid
    Arthur F Gelb
    Department of Medicine, Pulmonary Division, Lakewood Regional Medical Center, Lakewood, CA 90712, USA
    J Allergy Clin Immunol 129:1491-8. 2012
    ..The importance of monitoring exhaled nitric oxide (NO) in asthma remains controversial...
  4. ncbi request reprint Unsuspected pseudophysiologic emphysema in chronic persistent asthma
    A F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, University of California, Los Angeles, CA, USA
    Am J Respir Crit Care Med 162:1778-82. 2000
    ..The high incidence of loss of lung elastic recoil in chronic persistent asthma was unexpected, and its contribution to abnormal lung function needs to be emphasized...
  5. doi request reprint Bronchodilator efficacy of the fixed combination of ipratropium and albuterol compared to albuterol alone in moderate-to-severe persistent asthma
    Arthur F Gelb
    Pulmonary Division, Lakewood Regional Medical Center, Lakewood, CA, USA
    Pulm Pharmacol Ther 21:630-6. 2008
    ..The potential of anticholinergics to provide bronchodilatory benefits over short-acting beta(2)-agonists (SABA) alone in patients with moderate-to-severe persistent asthma has not been well defined...
  6. pmc Effect of fluticasone 250 microg/salmeterol 50 microg and montelukast on exhaled nitric oxide in asthmatic patients
    Arthur F Gelb
    Division of Pulmonary Services, Department of Medicine, Lakewood Regional Medical Center, Lakewood, Los Angeles, USA
    Can Respir J 15:193-8. 2008
    ..Monitoring noninvasive biomarkers of inflammation is an important adjunct in asthma therapy...
  7. doi request reprint Tiotropium induced bronchodilation and protection from dynamic hyperinflation is independent of extent of emphysema in COPD
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA, USA
    Pulm Pharmacol Ther 22:237-42. 2009
    ..The magnitude of tiotropium (1) induced bronchodilation and (2) protection against dynamic hyperinflation in COPD phenotypes has not been studied...
  8. doi request reprint Role of add-on zileuton on total exhaled, large airway, and small airway/alveolar nitric oxide in moderate-severe persistent adult asthmatics on fluticasone 250 microg/Salmeterol 50 microg
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA 90712, USA
    Pulm Pharmacol Ther 22:516-21. 2009
    ..Measuring non-invasive exhaled biomarkers of inflammation may be important in monitoring asthma therapy...
  9. doi request reprint Central and peripheral airway sites of nitric oxide gas exchange in COPD
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA, USA
    Chest 137:575-84. 2010
    ..This study investigated sites of nitric oxide (NO) gas exchange and response to inhaled corticosteroids (ICS) in patients with COPD and varying extents of emphysema...
  10. doi request reprint Central and peripheral airway/alveolar sites of exhaled nitric oxide in acute asthma
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, and Geffen School of Medicine, University of California at Los Angeles Medical Center, Lakewood, California, USA
    Thorax 65:619-25. 2010
    ..Central airway nitric oxide flux (J'(awNO)) and peripheral airway/alveolar nitric oxide concentration (C(ANO)) during asthma exacerbation has not been investigated after correction for axial NO back-diffusion...
  11. doi request reprint Increased nitric oxide concentrations in the small airway of older normal subjects
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA, USA
    Chest 139:368-75. 2011
    ..Our goal was to obtain normal data for large-airway nitric oxide flux (J'awno) and small-airway and/or alveolar nitric oxide concentration (Cano) in nonsmoking, healthy, adult subjects of various ages...
  12. doi request reprint Lack of protective effect of tiotropium vs induced dynamic hyperinflation in moderate COPD
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA 90712, USA
    Respir Med 105:755-60. 2011
    ..Novel evaluation of protective effect of tiotropium against induced dynamic hyperinflation (DH) during metronome paced hyperventilation (MPH) in moderate COPD...
  13. ncbi request reprint Physiologic similarities and differences between asthma and chronic obstructive pulmonary disease
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, California, USA
    Curr Opin Pulm Med 14:24-30. 2008
    ....
  14. ncbi request reprint Pseudophysiologic emphysema resulting from severe small-airways disease
    A F Gelb
    Departments of Medicine and Radiology, Lakewood Regional Medical Center, University of California Los Angeles, School of Medicine, Los Angeles, California, USA
    Am J Respir Crit Care Med 158:815-9. 1998
    ....
  15. ncbi request reprint Lung function 5 yr after lung volume reduction surgery for emphysema
    A F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, University of California, Los Angeles, California, USA
    Am J Respir Crit Care Med 163:1562-6. 2001
    ..0-4.5 yr. Bilateral LVRS provided palliative clinical and physiological improvement in 9 of 26 patients at 3 yr, 7 at 4 yr, and 2 at 5 yr...
  16. ncbi request reprint Lung elastic recoil in acute and chronic asthma
    Arthur F Gelb
    Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA 90712, USA
    Curr Opin Pulm Med 8:50-3. 2002
    ..No morphologic or physiologic abnormalities readily explain the chronic, persistent loss of lung recoil...
  17. ncbi request reprint Unsuspected loss of lung elastic recoil in chronic persistent asthma
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, Lakewood, CA, USA
    Chest 121:715-21. 2002
    ..To investigate the progression and mechanism(s) for fixed maximum expiratory airflow (max) limitation in patients with chronic persistent asthma...
  18. ncbi request reprint Alveolar and airway sites of nitric oxide inflammation in treated asthma
    Arthur F Gelb
    Department of Pharmacy Services, Lakewood Regional Medical Center, Lakewood, California, USA
    Am J Respir Crit Care Med 170:737-41. 2004
    ..002). Despite treatment, including inhaled corticosteroids, patients with asthma may have ongoing separate airway and alveolar sites of NO inflammation, the latter responsive to oral corticosteroids...
  19. ncbi request reprint Risk factors for near-fatal asthma
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, 3650 E South St, Suite 308, Lakewood, CA 90712, USA
    Chest 126:1138-46. 2004
    ..There is a paucity of lung function data in patients, both before and after episodes of near-fatal asthma (NFA), requiring transient endotracheal intubation and mechanical ventilation...
  20. ncbi request reprint Simplified detection of dynamic hyperinflation
    Arthur F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, 3650 E South St, Suite 308, Lakewood, CA 90712, USA
    Chest 126:1855-60. 2004
    ..To detect dynamic hyperinflation by comparing reduction in inspiratory capacity (IC) during both paced hyperventilation and cycle ergometry in patients with moderate-to-severe COPD, studied before and after acute bronchodilation...
  21. ncbi request reprint Role of spirometry and exhaled nitric oxide to predict exacerbations in treated asthmatics
    Arthur F Gelb
    Lakewood Regional Medical Center, Lakewood, CA 90712, USA
    Chest 129:1492-9. 2006
    ..To evaluate the complementary roles of exhaled nitric oxide (NO) and spirometry to predict asthma exacerbations requiring one or more tapering courses of systemic corticosteroids...
  22. ncbi request reprint Lung function 4 years after lung volume reduction surgery for emphysema
    A F Gelb
    Pulmonary Division, Department of Medicine, Lakewood Regional Medical Center, University of California Los Angeles, USA
    Chest 116:1608-15. 1999
    ..Current data for patients > 2 years after lung volume reduction surgery (LVRS) for emphysema is limited. This prospective study evaluates pre-LVRS baseline data and provides long-term results in 26 patients...
  23. ncbi request reprint Tiotropium and simplified detection of dynamic hyperinflation
    Arthur F Gelb
    Department of Pharmacy Services, Lakewood Regional Medical Center, Lakewood, CA 90712, USA
    Chest 131:690-5. 2007
    ..To detect dynamic hyperinflation (DH) by evaluating reduction in inspiratory capacity (IC) during metronome-paced hyperventilation (MPH) in patients with moderate-to-severe COPD, studied before and after treatment with tiotropium...
  24. ncbi request reprint Physiologic characteristics of malignant unilateral main-stem bronchial obstruction. Diagnosis and Nd-YAG laser treatment
    A F Gelb
    Department of Medicine, Doctors Hospital of Lakewood, California
    Am Rev Respir Dis 138:1382-5. 1988
    ..0 +/- 0.6 to 1.8 +/- 0.5 s-1 in patients without emphysema and from 0.8 +/- 0.3 to 0.8 +/- 0.1 s-1 in patients with emphysema.(ABSTRACT TRUNCATED AT 250 WORDS)..
  25. ncbi request reprint Pathophysiology of dyspnea in chronic obstructive pulmonary disease: a roundtable
    Denis E O'Donnell
    Department of Medicine, Queen s University, 102 Stuart Street, Kingston, ON, K7L 2V6 Canada
    Proc Am Thorac Soc 4:145-68. 2007
    ..Self-management strategies address the affective aspect of dyspnea and are essential to successful treatment...