Brett K Kaiser
Affiliation: Fred Hutchinson Cancer Research Center
- Xenopus Cdc14 alpha/beta are localized to the nucleolus and centrosome and are required for embryonic cell divisionBrett K Kaiser
Departments of Pathology and Microbiology and Immunology, Program in Cancer Biology, Stanford University School of Medicine, Stanford, CA 94305 USA
BMC Cell Biol 5:27. 2004..Therefore, it is of great interest to examine the function Cdc14 homologs in other vertebrate species...
- Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphataseBrett K Kaiser
Departments of Pathology and Microbiology, and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA
Mol Biol Cell 13:2289-300. 2002..Thus, the hCdc14A phosphatase appears to play a role in the regulation of the centrosome cycle, mitosis, and cytokinesis, thereby influencing chromosome partitioning and genomic stability in human cells...
- Control of the centriole and centrosome cycles by ubiquitination enzymesDavid V Hansen
Programs in Chemical Biology and Cancer Biology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California, CA 94305 5324, USA
Oncogene 21:6209-21. 2002
- Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregationNiels Mailand
Institute of Cancer Biology, Danish Cancer Society, Strandboulevarden 49, DK 2100 Copenhagen, Denmark
Nat Cell Biol 4:317-22. 2002..These results indicate that Cdc14A is a physiological regulator of the centrosome duplication cycle, which, when disrupted, can lead to genomic instability in mammalian cells...