Danielle M Friedrichsen
Affiliation: Fred Hutchinson Cancer Research Center
- IGF-I and IGFBP-3 polymorphisms and risk of prostate cancerDanielle M Friedrichsen
Division of Clinical Research and Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Prostate 65:44-51. 2005..Several polymorphisms within the IGF-I and IGFBP-3 coding regions have been associated with increased serum protein levels...
- Frequency of CHEK2 mutations in a population based, case-control study of breast cancer in young womenDanielle M Friedrichsen
Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Breast Cancer Res 6:R629-35. 2004..However, the 1100delC mutation has only been investigated in a few population-based studies and none from North America...
- Prostate cancer and genetic susceptibility: a genome scan incorporating disease aggressivenessJanet L Stanford
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, and Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98109 1024, USA
Prostate 66:317-25. 2006..Linkage studies attempting to map genes for hereditary prostate cancer (HPC) have proved challenging, and one potential problem contributing to this challenge is the variability in disease phenotypes...
- Identification of a prostate cancer susceptibility locus on chromosome 7q11-21 in Jewish familiesDanielle M Friedrichsen
Divisions of Clinical Research and Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Proc Natl Acad Sci U S A 101:1939-44. 2004..12 (P = 0.00007). These studies highlight the utility of analyzing defined sets of families with a common origin for reducing locus heterogeneity problems associated with studying complex traits...
- Vitamin D receptor gene polymorphisms and prostate cancer riskMahesh B Keitheri Cheteri
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Prostate 59:409-18. 2004..To further evaluate this relationship, we conducted a population-based case-control study of the VDR BsmI, FokI, and Poly-A polymorphisms, and prostate cancer...
- Prevalence and predictors of BRCA1 and BRCA2 mutations in a population-based study of breast cancer in white and black American women ages 35 to 64 yearsKathleen E Malone
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Cancer Res 66:8297-308. 2006....
- Genomic scan of 254 hereditary prostate cancer familiesMarta Janer
Institute for Systems Biology, Seattle, Washington, USA
Prostate 57:309-19. 2003..These analyses support the existence of multiple HPC loci, whose presence may be best identified by analyses of large, including pooled, datasets which consider locus heterogeneity...
- A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer geneticsJianfeng Xu
Center for Human Genomics, Wake Forest University School of Medicine, Winston Salem, NC, USA
Am J Hum Genet 77:219-29. 2005....
- Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer GeneticsDaniel J Schaid
Harwick 7, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Hum Genet 120:471-85. 2006..This provides a basis for attempts to identify these genes, with potential clinical utility for men with aggressive prostate cancer and their relatives...
- A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer riskGoutham Narla
Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA
Cancer Res 65:1213-22. 2005....