Affiliation: Fred Hutchinson Cancer Research Center
- Evidence in support of foster care during acute refugee crisesAnn Duerr
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA, USA
Am J Public Health 93:1904-9. 2003..We examined evidence to support this policy using data from the 1994 Rwandan refugee crisis...
- Extended follow-up confirms early vaccine-enhanced risk of HIV acquisition and demonstrates waning effect over time among participants in a randomized trial of recombinant adenovirus HIV vaccine (Step Study)Ann Duerr
Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington 98109 1024, USA
J Infect Dis 206:258-66. 2012..Follow-up was extended to assess relative risk of HIV acquisition in vaccinees vs placebo recipients over time...
- Integrating family planning and prevention of mother-to-child HIV transmission in resource-limited settingsAnn Duerr
Centers for Disease Control and Prevention, Atlanta, GA, USA
Lancet 366:261-3. 2005
- HIV vaccines: new frontiers in vaccine developmentAnn Duerr
Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
Clin Infect Dis 43:500-11. 2006..The most immunogenic of these products appear to be the recombinant adenovirus vector vaccines, 2 of which are now in advanced clinical development...
- Update on mucosal HIV vaccine vectorsAnn Duerr
HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Curr Opin HIV AIDS 5:397-403. 2010..Recent advances in measuring adaptive responses at mucosal sites and optimization of techniques for low-dose repeated mucosal challenge in nonhuman primate animal models allow more in depth studies of mucosal vaccine vectors...
- Efficacy of the male latex condom and of the female polyurethane condom as barriers to semen during intercourse: a randomized clinical trialMaurizio Macaluso
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA, USA
Am J Epidemiol 166:88-96. 2007..Objectively assessed semen exposure is associated with self-reported mechanical problems...
- Nutritional biomarkers associated with gynecological conditions among US women with or at risk of HIV infectionBeth C Tohill
Centers for Disease Control and Prevention, National Center for Chronic Disease and Public Health Prevention, Division of Nutrition and Physical Activity and Division of Reproductive Health, Atlanta, GA 30341, USA
Am J Clin Nutr 85:1327-34. 2007..This relation among HIV, nutrition, and gynecological conditions is complex and has rarely been investigated...
- Effect of HIV infection on atypical squamous cells of undetermined significanceAnn Duerr
Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Clin Infect Dis 42:855-61. 2006..Detection of atypical squamous cells of undetermined significance (ASCUS) is a cervical cytologic finding that is suggestive but not definitive of squamous intraepithelial lesions (SILs)...
- Vulvar, vaginal, and perianal intraepithelial neoplasia in women with or at risk for human immunodeficiency virusDenise J Jamieson
Womens Health and Fertility Branch, Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Obstet Gynecol 107:1023-8. 2006..To compare the incidence of vulvar, vaginal, and perianal intraepithelial neoplasia among human immunodeficiency virus (HIV)-infected women with a group of well-matched high-risk HIV-uninfected controls...
- Assessing male condom failure and incorrect useAnn Duerr
Division of Clinical Research and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Sex Transm Dis 38:580-6. 2011..It has not been well established whether common indices of male condom failure are valid predictors of biologically meaningful exposure during condom use...
- Breast milk CD4+ T cells express high levels of C chemokine receptor 5 and CXC chemokine receptor 4 and are preserved in HIV-infected mothers receiving highly active antiretroviral therapyAthena P Kourtis
Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
J Infect Dis 195:965-72. 2007..Little characterization of breast milk CD4(+) T lymphocytes has been done so far...
- Vaginal flora morphotypic profiles and assessment of bacterial vaginosis in women at risk for HIV infectionBeth C Tohill
Centers for Disease Control and Prevention, National Center for Chronic Disease and Public Health Prevention, Division of Nutrition and Physical Activity, Atlanta, GA 30341, USA
Infect Dis Obstet Gynecol 12:121-6. 2004..The proposed profiles from the Gram stain reflect the morphotypic categories describing vaginal flora that may enable clearer elucidation of gynecologic and obstetric outcomes in various populations...
- Viral load and CD4 count dynamics after HIV-1 seroconversion in homosexual and bisexual men in Rio de Janeiro, BrazilGaston Djomand
HIV Vaccine Trials Network, Seattle, WA, USA
J Acquir Immune Defic Syndr 43:401-4. 2006..Reliable predictors of HIV disease progression are scarce in developing countries, where most HIV infections occur. We describe early virologic and immunologic events among men who have sex with men in Rio de Janeiro, Brazil...
- HIV-1 infections with multiple founders are associated with higher viral loads than infections with single foundersHolly Janes
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Nat Med 21:1139-41. 2015....
- Serological immunity to adenovirus serotype 5 is not associated with risk of HIV infection: a case-control studyMarcel E Curlin
Vaccine and Infectious Diseases Institute, Fred Hutchinson Cancer Research Center, USA
AIDS 25:153-8. 2011..We examined the association between adenovirus serostatus and the rate of incident HIV infection in populations at elevated risk of HIV acquisition...
- Human adenovirus-specific T cells modulate HIV-specific T cell responses to an Ad5-vectored HIV-1 vaccineNicole Frahm
Vaccine and Infectious Disease Division and HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
J Clin Invest 122:359-67. 2012..These findings provide what we believe to be a new understanding of how preexisting viral immunity may impact the efficacy of vaccines under current evaluation for prevention of HIV, tuberculosis, and malaria...
- Reasons for testing and clinical and demographic profile of adolescents with non-perinatally acquired HIV infectionAlthea M Grant
Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Pediatrics 117:e468-75. 2006....
- Seroprevalence of human herpesvirus 8 infection in Northern ThailandNora Chen
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Clin Infect Dis 39:1052-8. 2004..2% of reported patients with AIDS in Thailand had KS), we determined the HHV-8 seroprevalence among populations who were HIV positive or at risk of HIV infection...
- Predictors of low CD4 count in resource-limited settings: based on an antiretroviral-naive heterosexual thai populationCaroline Costello
Centers for Disease Control and Prevention, Atlanta, GA, USA
J Acquir Immune Defic Syndr 39:242-8. 2005..0% in men, 68.2% in women) with less than a 6% decrease in specificity...
- Immune-correlates analysis of an HIV-1 vaccine efficacy trial reveals an association of nonspecific interferon-γ secretion with increased HIV-1 infection risk: a cohort-based modeling studyYunda Huang
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
PLoS ONE 9:e108631. 2014..We assessed pre-infection cellular immune responses measured at 4 weeks after the second vaccination to determine their roles in HIV-1 infection susceptibility among Step study male participants...
- Incident and persistent vulvovaginal candidiasis among human immunodeficiency virus-infected women: Risk factors and severityAnn Duerr
National Center for Chronic Disease Prevention and Health Promotion, Division of Reproductive Health HIV Section, Centers for Disease Control and Prevention, Mailstop K 34, 4770 Buford Highway NE, Atlanta, GA 30341 3717, USA
Obstet Gynecol 101:548-56. 2003..To examine risk factors for vulvovaginal candidiasis among women with or at risk for human immunodeficiency virus (HIV) infection...
- The potential role of biomarkers in HIV preventive vaccine trialsEllen Maclachlan
HIV Vaccine Trials Network HVTN, Fred Hutchinson Cancer Research Center FHCRC, Seattle, WA, USA
J Acquir Immune Defic Syndr 51:536-45. 2009..Although not invariably useful and bringing their own cost in terms of measurement and validation, a variety of biomarkers may aid at each stage of trial conduct...
- HIV vaccine efficacy trials: towards the future of HIV preventionDenny Kim
HIV Vaccine Trials Network, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
Infect Dis Clin North Am 21:201-17, x. 2007..Adenovirus vector-based regimens that induce CTLs are currently in efficacy trial testing. These efficacy trials are using surrogate end points in an innovative Phase 2B trial design...
- Effect of contraceptive methods on natural history of HIV: studies from the Mombasa cohortJared M Baeten
University of Washington, Seattle, WA, USA
J Acquir Immune Defic Syndr 38:S18-21. 2005
- Addition of 7 days of zidovudine plus lamivudine to peripartum single-dose nevirapine effectively reduces nevirapine resistance postpartum in HIV-infected mothers in MalawiSherry L Farr
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30345, USA
J Acquir Immune Defic Syndr 54:515-23. 2010..We assessed whether 7 days of zidovudine + lamivudine postpartum with single-dose nevirapine at labor decreases nevirapine resistance in HIV-infected women in Malawi...
- Self-reported mechanical problems during condom use and semen exposure. Comparison of two randomized trials in the United States of America and BrazilMichael P Chen
Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Sex Transm Dis 34:557-62. 2007..OBJECTIVES/GOAL: To compare self-reported condom use problems and objectively determined semen exposure in 2 populations...
- Safe conception for HIV discordant couples through sperm-washing: experience and perceptions of patients in Milan, ItalySaswati Sunderam
Social Scientist and Statistician, Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta GA, USA
Reprod Health Matters 16:211-9. 2008..They perceived assisted conception services to be a safe and effective alternative to spontaneous conception, and felt that society has a moral obligation to provide such services...
- Effect of rAd5-Vector HIV-1 Preventive Vaccines on HIV-1 Acquisition: A Participant-Level Meta-Analysis of Randomized TrialsYunda Huang
Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
PLoS ONE 10:e0136626. 2015..Rigorous meta-analysis can provide crucial information to advise the future utility of rAd5-vector vaccines...
- Genetic impact of vaccination on breakthrough HIV-1 sequences from the STEP trialMorgane Rolland
Department of Microbiology, University of Washington, Seattle, Washington, USA
Nat Med 17:366-71. 2011..These results represent what is to our knowledge the first evidence of selective pressure from vaccine-induced T cell responses on HIV-1 infection in humans...
- Broad human immunodeficiency virus (HIV)-specific T cell responses to conserved HIV proteins in HIV-seronegative women highly exposed to a single HIV-infected partnerNattawan Promadej
Centers for Disease Control and Prevention, Emory University, Atlanta, Georgia, USA
J Infect Dis 187:1053-63. 2003..Remarkably, however, long-lived HIV-specific T cells were detected in 2 HW who had an extended period (>3.9 years) of no HIV exposure. These findings have important implications for HIV vaccine design...
- Maternal mortality among Afghan refugees in Pakistan, 1999-2000Linda A Bartlett
Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Lancet 359:643-9. 2002..Estimated at 3.6 million, Afghans are the largest population of refugees in the world. Information on the magnitude, causes, and preventable factors of maternal deaths among Afghan refugees may yield valuable information for prevention...
- Knowledge and preferences concerning acute HIV testing programs among both Peruvian men who have sex with men and transgender womenGrace M Wandell
1 University of Washington School of Medicine, Seattle, WA, USA
Int J STD AIDS . 2017..The shortened window period with AHI testing would encourage testing following high-risk sex. Delayed result notification would not decrease AHI testing demand among MSM, although it might for some TW...
- Characterization of genital human papillomavirus infection in women who have or who are at risk of having HIV infectionDenise J Jamieson
Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Obstet Gynecol 186:21-7. 2002....
- Coreceptor utilization of HIV type 1 subtype E viral isolates from Thai men with HIV type 1-infected and uninfected wivesUtaiwan Utaipat
HIV Immunology and Diagnostics Branch, DASTLR, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
AIDS Res Hum Retroviruses 18:1-11. 2002..Thus, there was no association between the pattern of coreceptor usage and transmissibility among these subtype E HIV-1 isolates...
- Prevention of perinatal HIV transmission: a review of novel strategiesAthena P Kourtis
Eastern Virginia Medical School, Norfolk, USA
Expert Opin Investig Drugs 12:1535-44. 2003....
- Endpoints and regulatory issues in HIV vaccine clinical trials: lessons from a workshopDean Follmann
National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
J Acquir Immune Defic Syndr 44:49-60. 2007..Use of acquisition and a postinfection surrogate as coprimary endpoints was supported, along with use of composite endpoints and exploration of heterogeneity in vaccine efficacy by characteristics of the host and virus...
- Breast milk and HIV-1: vector of transmission or vehicle of protection?Athena P Kourtis
Eastern Virginia Medical School, Norfolk, VA, USA
Lancet Infect Dis 3:786-93. 2003....
- Abnormal vaginal cytology in HIV-infected and at-risk women after hysterectomyPangaja Paramsothy
Contraceptive Research and Development CONRAD Program, Arlington, VA, USA
J Acquir Immune Defic Syndr 35:484-91. 2004..To determine the frequency of and risk factors for abnormal vaginal Papanicolaou smears in HIV-infected women after hysterectomy...
- Male viral load and heterosexual transmission of HIV-1 subtype E in northern ThailandSodsai Tovanabutra
Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand
J Acquir Immune Defic Syndr 29:275-83. 2002....
- The impact of HIV infection and immunodeficiency on human papillomavirus type 6 or 11 infection and on genital wartsMichael J Silverberg
Johns Hopkins School of Public Health, Baltimore, Maryland 21205, USA
Sex Transm Dis 29:427-35. 2002..HIV infection and associated immunodeficiency are known to alter the course of human papillomavirus (HPV) infections and of associated diseases...
- Human immunodeficiency virus (HIV)-specific antibody in cervicovaginal lavage specimens obtained from women infected with HIV type 1Selvi B Williams
Department of Medicine, Brown University School of Medicine, Providence, RI 02906, USA
Clin Infect Dis 35:611-7. 2002..0474) compared with women who did not have bacterial vaginosis. Enhanced understanding of correlates of mucosal immunity to HIV-1 may assist in the design of vaccine strategies or in the prevention of vertical transmission of HIV-1...
- Serum immunoglobulin G response to human papillomavirus type 16 virus-like particles in human immunodeficiency virus (HIV)-positive and risk-matched HIV-negative womenRaphael P Viscidi
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Infect Dis 187:194-205. 2003..Despite the higher prevalence of HPV infection in this group, most HIV-positive women are able to control HPV-16 replication at the cervix, and reactivation, if it occurs, is not very common...
- Longitudinal study of mucosal Candida species colonization and candidiasis among human immunodeficiency virus (HIV)-seropositive and at-risk HIV-seronegative womenSuzanne E Ohmit
Wayne State University School of Medicine, Detroit, Michigan, USA
J Infect Dis 188:118-27. 2003..In HIV-seropositive women, mucosal candidiasis is the consequence of multiple interacting factors...
- Longitudinal study of cervical squamous intraepithelial lesions in human immunodeficiency virus (HIV)-seropositive and at-risk HIV-seronegative womenPaula Schuman
Wayne State University School of Medicine, Detroit, Michigan 48109, USA
J Infect Dis 188:128-36. 2003..SIL regression was less likely among HIV-seropositive women with higher HIV loads. No beneficial effect of highly active antiretroviral therapy was demonstrated...
- High prevalence of self-reported forced sexual intercourse among internally displaced women in AzerbaijanJamila Kerimova
Relief International, Baku, Azerbaijan
Am J Public Health 93:1067-70. 2003
- Human papillomavirus type 16 and immune status in human immunodeficiency virus-seropositive womenHoward D Strickler
Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
J Natl Cancer Inst 95:1062-71. 2003..To address this issue, we examined HPV test results from repeated study visits in the WIHS and from an independent study, the HIV Epidemiology Research Study (HERS)...
- Lymphocyte homeostasis in HIV-infected northern ThaisDoungnapa Kingkeow
Research Institute for Health Sciences, Chiang Mai University, Thailand
AIDS Res Hum Retroviruses 20:636-41. 2004..2%, -12.0%) annually from 4.5 to 2 years prior to death and 63.7% (-72.3%, -53.6%) annually over the remaining 2 years. Similar lymphocyte patterns have been reported in U. S. and European populations with HIV-1 subtype B infection...
- Survival of blood donors and their spouses with HIV-1 subtype E (CRF01 A_E) infection in northern Thailand, 1992-2007Kenrad E Nelson
Department of Epidemiology, Johns Hopkins University, Bloomberg School of PublicHealth, 615N Wolfe Street, Baltimore, Maryland 21205, USA
AIDS 21:S47-54. 2007..To evaluate the survival patterns among adults in Thailand 8-14 years after HIV-1 subtype E (CRF01 A_E) infection...
- Inclusion of adolescents in preventive HIV vaccine trials: public health policy and research design at a crossroadsHeather B Jaspan
Desmond Tutu HIV Centre, University of Cape Town, South Africa
J Acquir Immune Defic Syndr 47:86-92. 2008..This article examines these issues and proposes specific next steps to facilitate the routine inclusion of this high-priority population in preventive HIV vaccine trials as early and seamlessly as possible...
- Do women with HIV infection have different indications for hysterectomy?Pangaja Paramsothy
J Acquir Immune Defic Syndr 39:378-9. 2005
- Accuracy of Papanicolaou test among HIV-infected womenJean R Anderson
Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Clin Infect Dis 42:562-8. 2006..We examined the accuracy of the Papanicolaou (Pap) test among women with and women at high risk for human immunodeficiency virus (HIV) infection...
- HIV-discordant couples and parenthood: how are we dealing with the risk of transmission?Pietro L Vernazza
AIDS 20:635-6. 2006
- Time to clearance of human papillomavirus infection by type and human immunodeficiency virus serostatusJill E Koshiol
Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA
Int J Cancer 119:1623-9. 2006..57 (95% CI: 0.22-1.45) for HIV-positive and -negative women, respectively. HPV types within the high-risk category had low estimated clearance rates relative to low-risk types, but HRs were not substantially modified by HIV serostatus...
- Outcomes after treatment of cervical intraepithelial neoplasia among women with HIVL Stewart Massad
Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Springfield, IL 62794 9640, USA
J Low Genit Tract Dis 11:90-7. 2007..To describe outcomes after treatment of cervical intraepithelial neoplasia (CIN) in women with HIV...
- Involving communities in the design of clinical trial protocols: the BAN Study in Lilongwe, MalawiAmy L Corneli
University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Contemp Clin Trials 28:59-67. 2007....
- T-lymphocyte profile and total and virus-specific immunoglobulin concentrations in the cervix of HIV-1-infected womenAlison J Quayle
Department of Immunology, Microbiology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA, USA
J Acquir Immune Defic Syndr 44:292-8. 2007..The mucosal lymphocyte population is the largest in the body, and the gastrointestinal compartment has been well characterized in HIV infection. Much less is known about the effects of HIV on the genital tract...
- Reproductive options for HIV-serodiscordant couplesPablo Barreiro
Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain
AIDS Rev 8:158-70. 2006..This review discusses the pros and cons of reproductive options in HIV-infected persons and proposes a protocol for their counseling...