Abby A Li
Affiliation: Exponent Inc
- Pesticide exposure and neurodevelopmental outcomes: review of the epidemiologic and animal studiesCarol J Burns
The Dow Chemical Company, Midland, Michigan, USA
J Toxicol Environ Health B Crit Rev 16:127-283. 2013..S. Environmental Protection Agency (EPA). Suggestions for improved exposure assessment in epidemiology studies and more effective and tiered approaches in animal testing are discussed...
- Integration of epidemiology and animal neurotoxicity data for risk assessmentAbby A Li
Exponent Health Sciences, Menlo Park, CA 94025, USA
Neurotoxicology 33:823-32. 2012....
- Evaluation of epidemiology and animal data for risk assessment: chlorpyrifos developmental neurobehavioral outcomesAbby A Li
Exponent Health Sciences Group, Menlo Park, California, USA
J Toxicol Environ Health B Crit Rev 15:109-84. 2012..Neurodevelopmental behavioral, pharmacological, and morphologic effects occurred at doses that produced significant brain or red blood cell acetylcholinesterase inhibition in dams or offspring...
- Evaluation of epidemiologic and animal data associating pesticides with Parkinson's diseaseAbby A Li
Health Sciences Practice, Exponent, Inc, San Francisco, California 94114, USA
J Occup Environ Med 47:1059-87. 2005..We conclude that the animal and epidemiologic data reviewed do not provide sufficient evidence to support a causal association between pesticide exposure and PD...
- Building a scientific framework for studying hormonal effects on behavior and on the development of the sexually dimorphic nervous systemAbby A Li
Exponent Health Sciences, San Francisco, CA 94114, USA
Neurotoxicology 29:504-19. 2008..Understanding of the hormonal mechanisms of these behaviors, and of relevance to humans, is needed to develop biologically plausible hypotheses regarding the potential effects of hormonally active chemicals in humans...
- Oral gavage subchronic neurotoxicity and inhalation subchronic immunotoxicity studies of ethylbenzene in the ratAbby A Li
Exponent Inc, 1010 14th St, San Francisco, CA 94114, United States
Neurotoxicology 31:247-58. 2010..The no-observed-adverse-effect level (NOAEL) for adult neurotoxicity was the highest dose tested 500 mg/kg bwt/day. The NOAEL for the immunotoxicity evaluation was the highest tested exposure concentration, 500 ppm (342 mg/kg bwt/day)...
- Potential effects of chlorpyrifos on fetal growth outcomes: implications for risk assessmentPamela J Mink
Exponent, Inc, Health Sciences Group, Menlo Park, California 94025 1133, USA
J Toxicol Environ Health B Crit Rev 15:281-316. 2012..Based on consideration of both the epidemiologic and animal data, maternal RBC AChE inhibition is a more sensitive endpoint for risk assessment than somatic developmental effects reviewed in this article...
- Recommended Methods for Brain Processing and Quantitative Analysis in Rodent Developmental Neurotoxicity StudiesRobert H Garman
Consultants in Veterinary Pathology, Inc, Murrysville, Pennsylvania, USA
Toxicol Pathol 44:14-42. 2016....
- Neurobehavioral assessment: a survey of use and value in safety assessment studiesLawrence D Middaugh
Department of Psychiatry and Behavioral Science, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Toxicol Sci 76:250-61. 2003..The survey results emphasize the need for further research into the methods of behavioral assessment as well as the mechanisms underlying the neurobehavioral alterations...