David S Yu

Summary

Affiliation: Emory University
Country: USA

Publications

  1. pmc One stone, two birds: CDK9-directed activation of UBE2A regulates monoubiquitination of both H2B and PCNA
    Hui Zhang
    Department of Radiation Oncology Emory University School of Medicine Atlanta, GA USA
    Cell Cycle 11:2418. 2012
  2. pmc A role for CDK9-cyclin K in maintaining genome integrity
    David S Yu
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, USA
    Cell Cycle 10:28-32. 2011
  3. pmc ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA
    Hui Zhang
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Cell Rep 14:1435-47. 2016
  4. pmc Chromodomain-helicase-DNA binding protein 5, 7 and pronecrotic mixed lineage kinase domain-like protein serve as potential prognostic biomarkers in patients with resected pancreatic adenocarcinomas
    Crystal S Seldon
    Crystal S Seldon, David S Yu, Jerome C Landry, Department of Radiation Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, United States
    World J Gastrointest Oncol 8:358-65. 2016
  5. doi request reprint Cholangiocarcinoma size on magnetic resonance imaging versus pathologic specimen: Implications for radiation treatment planning
    Daniel G Tanenbaum
    Department of Radiation Oncology, Atlanta, Georgia Winship Cancer Institute, Emory University, Atlanta, Georgia
    Pract Radiat Oncol 6:201-6. 2016
  6. pmc TNFRSF10C copy number variation is associated with metastatic colorectal cancer
    Daniel G Tanenbaum
    1 Department of Radiation Oncology, 2 Winship Cancer Institute, Emory University, GA, USA 3 Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, USA 4 Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA 5 Department of Pathology and Laboratory Medicine, 6 Department of Biomedical Informatics, 7 Department of Biostatistics and Bioinformatics, 8 Biostatistics and Bioinformatics Research Center, Cedars Sinai Medical Center, Los Angeles, CA, USA
    J Gastrointest Oncol 7:306-14. 2016
  7. pmc A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response
    Scott C Smith
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Nucleic Acids Res 42:11517-27. 2014
  8. pmc Pronecrotic mixed lineage kinase domain-like protein expression is a prognostic biomarker in patients with early-stage resected pancreatic adenocarcinoma
    Lauren E Colbert
    Department of Radiation Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia
    Cancer 119:3148-55. 2013
  9. pmc Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
    David S Yu
    Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    EMBO Rep 11:876-82. 2010
  10. pmc SIRT2 directs the replication stress response through CDK9 deacetylation
    Hui Zhang
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 110:13546-51. 2013

Collaborators

  • William A Hall
  • David A Kooby
  • Ya Wang
  • Shishir K Maithel
  • Nicholas T Seyfried
  • Xingming Deng
  • Jie Wang
  • Walter J Curran
  • N Volkan Adsay
  • Charles A Staley
  • Hui Zhang
  • Lauren E Colbert
  • Daniel G Tanenbaum
  • Jerome C Landry
  • Matthew D Warren
  • Sarah B Fisher
  • Claire W Hardy
  • Crystal S Seldon
  • Elaine A Liu
  • Mylin A Torres
  • Matthew Z Madden
  • Yunfeng Pan
  • Duc M Duong
  • Jeanne Kowalski
  • David Gius
  • Seong Hoon Park
  • Scott C Smith
  • Aleksandra V Petrova
  • Brooke G Pantazides
  • Daniel J Brat
  • Amanda J Bastien
  • Xingzhe Li
  • Dana C Nickleach
  • Courtney C Moreno
  • PamelaSara E Head
  • Chunyang Li
  • Pardeep Mittal
  • Sungjin Kim
  • Vishal R Dhere
  • John L Mikell
  • Paul W Doetsch
  • Jun Kong
  • Malcolm H Squires
  • William S Dynan
  • Bing Yu
  • Ivan Pradilla
  • Bhakti Dwivedi
  • Maohua Xie
  • Waaqo Daddacha
  • Dong Liang
  • Soumon Rudra
  • M Hope Robinson
  • Shahrzad Ehdaivand
  • Hongyan Wang
  • So Jeong Park
  • Athanassios Vassilopoulos
  • Oleksandra Karpiuk
  • Hyun Seok Kim
  • Khanjan Gandhi
  • Burcu Saka
  • Steven A Johnsen
  • Bassel F El-Rayes
  • Joseph W Shelton

Detail Information

Publications10

  1. pmc One stone, two birds: CDK9-directed activation of UBE2A regulates monoubiquitination of both H2B and PCNA
    Hui Zhang
    Department of Radiation Oncology Emory University School of Medicine Atlanta, GA USA
    Cell Cycle 11:2418. 2012
    ..Comment on: Shchebet A, et al. Cell Cycle 2012; 11:2122-7...
  2. pmc A role for CDK9-cyclin K in maintaining genome integrity
    David S Yu
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA, USA
    Cell Cycle 10:28-32. 2011
    ..The direct role of CDK9-cyclin K in pathways that maintain genome integrity in response to replication stress appear to be evolutionarily conserved...
  3. pmc ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA
    Hui Zhang
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Cell Rep 14:1435-47. 2016
    ....
  4. pmc Chromodomain-helicase-DNA binding protein 5, 7 and pronecrotic mixed lineage kinase domain-like protein serve as potential prognostic biomarkers in patients with resected pancreatic adenocarcinomas
    Crystal S Seldon
    Crystal S Seldon, David S Yu, Jerome C Landry, Department of Radiation Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322, United States
    World J Gastrointest Oncol 8:358-65. 2016
    ..Based on the data presented, these biomarkers warrant further investigation, and should be validated in future studies. ..
  5. doi request reprint Cholangiocarcinoma size on magnetic resonance imaging versus pathologic specimen: Implications for radiation treatment planning
    Daniel G Tanenbaum
    Department of Radiation Oncology, Atlanta, Georgia Winship Cancer Institute, Emory University, Atlanta, Georgia
    Pract Radiat Oncol 6:201-6. 2016
    ..We aim to investigate the concordance between imaging and pathologic size in patients with resected CC to determine the usefulness of MRI for image guided treatment modalities...
  6. pmc TNFRSF10C copy number variation is associated with metastatic colorectal cancer
    Daniel G Tanenbaum
    1 Department of Radiation Oncology, 2 Winship Cancer Institute, Emory University, GA, USA 3 Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI, USA 4 Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA 5 Department of Pathology and Laboratory Medicine, 6 Department of Biomedical Informatics, 7 Department of Biostatistics and Bioinformatics, 8 Biostatistics and Bioinformatics Research Center, Cedars Sinai Medical Center, Los Angeles, CA, USA
    J Gastrointest Oncol 7:306-14. 2016
    ..We evaluated the association of tumor necrosis factor receptor superfamily member 10C (TNFRSF10C) copy number variation (CNV) with distant metastatic disease in patients with CRC using The Cancer Genome Atlas (TCGA)...
  7. pmc A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response
    Scott C Smith
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Nucleic Acids Res 42:11517-27. 2014
    ..Thus, NEK9 is a critical component of the RSR that promotes CHK1 activity, maintaining genome integrity following challenges to DNA replication. ..
  8. pmc Pronecrotic mixed lineage kinase domain-like protein expression is a prognostic biomarker in patients with early-stage resected pancreatic adenocarcinoma
    Lauren E Colbert
    Department of Radiation Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia
    Cancer 119:3148-55. 2013
    ..The goal of the current study was to evaluate the prognostic value of MLKL expression in patients with pancreatic adenocarcinoma (PAC)...
  9. pmc Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
    David S Yu
    Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    EMBO Rep 11:876-82. 2010
    ..These results reveal an unexpectedly direct role for CDK9-cyclin K in checkpoint pathways that maintain genome integrity in response to replication stress...
  10. pmc SIRT2 directs the replication stress response through CDK9 deacetylation
    Hui Zhang
    Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Proc Natl Acad Sci U S A 110:13546-51. 2013
    ....