Guang Jer Wu

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi Expression of a human cell adhesion molecule, MUC18, in prostate cancer cell lines and tissues
    G J Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Prostate 48:305-15. 2001
  2. ncbi Isolation and characterization of the major form of human MUC18 cDNA gene and correlation of MUC18 over-expression in prostate cancer cell lines and tissues with malignant progression
    G J Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Gene 279:17-31. 2001
  3. ncbi Ectopical expression of human MUC18 increases metastasis of human prostate cancer cells
    Guang Jer Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Gene 327:201-13. 2004
  4. ncbi Increased expression of MUC18 correlates with the metastatic progression of mouse prostate adenocarcinoma in the TRAMP model
    Guang Jer Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Urol 173:1778-83. 2005
  5. doi Enforced expression of MCAM/MUC18 increases in vitro motility and invasiveness and in vivo metastasis of two mouse melanoma K1735 sublines in a syngeneic mouse model
    Guang Jer Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mol Cancer Res 6:1666-77. 2008
  6. pmc Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells
    Guo Fang Zeng
    Bioengineering College, Chongqing University, Chongqing 400044, China
    BMC Cancer 11:113. 2011
  7. ncbi Oral treatment of the TRAMP mice with doxazosin suppresses prostate tumor growth and metastasis
    Cheng Feng Chiang
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Prostate 64:408-18. 2005
  8. ncbi Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model
    Chia Ling Hsieh
    Molecular Urology and Therapeutic Program, Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Prostate 67:685-91. 2007
  9. doi Enforced expression of METCAM/MUC18 increases tumorigenesis of human prostate cancer LNCaP cells in nude mice
    Guang Jer Wu
    Department of Microbiology and Immunology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA
    J Urol 185:1504-12. 2011
  10. pmc METCAM/MUC18 is a novel tumor and metastasis suppressor for the human ovarian cancer SKOV3 cells
    Guang Jer Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA
    BMC Cancer 16:136. 2016

Collaborators

Detail Information

Publications11

  1. ncbi Expression of a human cell adhesion molecule, MUC18, in prostate cancer cell lines and tissues
    G J Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Prostate 48:305-15. 2001
    ....
  2. ncbi Isolation and characterization of the major form of human MUC18 cDNA gene and correlation of MUC18 over-expression in prostate cancer cell lines and tissues with malignant progression
    G J Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Gene 279:17-31. 2001
    ..Furthermore, the lacking of predominant cytoplasmic membrane expression of MUC18 appeared to correlate with malignant progression of prostate cancer...
  3. ncbi Ectopical expression of human MUC18 increases metastasis of human prostate cancer cells
    Guang Jer Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Gene 327:201-13. 2004
    ..We therefore conclude that HuMUC18 is an important determinant in increasing metastasis of human prostate cancer LNCaP cells to distant organs in a nude mouse model...
  4. ncbi Increased expression of MUC18 correlates with the metastatic progression of mouse prostate adenocarcinoma in the TRAMP model
    Guang Jer Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Urol 173:1778-83. 2005
    ..In this study we investigated the possible correlation of increased MUC18 expression with the malignant progression of prostate cancer in the TRAMP model...
  5. doi Enforced expression of MCAM/MUC18 increases in vitro motility and invasiveness and in vivo metastasis of two mouse melanoma K1735 sublines in a syngeneic mouse model
    Guang Jer Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Mol Cancer Res 6:1666-77. 2008
    ....
  6. pmc Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells
    Guo Fang Zeng
    Bioengineering College, Chongqing University, Chongqing 400044, China
    BMC Cancer 11:113. 2011
    ..To resolve this, we have re-investigated the role of this CAM in the progression of human breast cancer cells...
  7. ncbi Oral treatment of the TRAMP mice with doxazosin suppresses prostate tumor growth and metastasis
    Cheng Feng Chiang
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Prostate 64:408-18. 2005
    ..We used the TRAMP mouse model for testing the effect of oral doxazosin treatment on the in vivo prostate tumor growth and metastasis...
  8. ncbi Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model
    Chia Ling Hsieh
    Molecular Urology and Therapeutic Program, Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Prostate 67:685-91. 2007
    ....
  9. doi Enforced expression of METCAM/MUC18 increases tumorigenesis of human prostate cancer LNCaP cells in nude mice
    Guang Jer Wu
    Department of Microbiology and Immunology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA
    J Urol 185:1504-12. 2011
    ..To investigate this and determine whether human metastasis cell adhesion molecule/MUC18 may act as a possible tumor progression gene, we studied the effect of its enforced expression on LNCaP cell tumorigenesis...
  10. pmc METCAM/MUC18 is a novel tumor and metastasis suppressor for the human ovarian cancer SKOV3 cells
    Guang Jer Wu
    Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, GA, 30322, USA
    BMC Cancer 16:136. 2016
    ....
  11. doi Frequent and increased expression of human METCAM/MUC18 in cancer tissues and metastatic lesions is associated with the clinical progression of human ovarian carcinoma
    Guang Jer Wu
    Department of Microbiology and Immunology and The Winship Cancer Institute, Emory University School of Medicine, Rollins Research Center, Atlanta, GA 30322, USA Department of Bioscience Technology, Chung Yuan Christian University, Chung Li 32023, Taiwan Electronic address
    Taiwan J Obstet Gynecol 53:509-17. 2014
    ..To initiate the study we determined expression of this protein in normal and cancerous ovarian tissues, cystadenomas, metastatic lesions, and ovarian cancer cell lines...