Affiliation: Emory University
- Lipids and vascular disease: a framingham perspectivePeter W F Wilson
Atlanta Veterans Affairs Medical Center, and Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA Electronic address
Glob Heart 8:25-33. 2013..The information is presented chronologically to highlight the developments related to the lipids and heart disease over the past 50 years. ..
- Genome-wide association with select biomarker traits in the Framingham Heart StudyEmelia J Benjamin
The National Heart Lung and Blood Institute s Framingham Heart Study, Framingham, MA, USA
BMC Med Genet 8:S11. 2007..Genome-wide association studies (GWAS) provide mechanisms to investigate the genetic contributions to biomarker variability unconstrained by current knowledge of physiological relations...
- Evidence of systemic inflammation and estimation of coronary artery disease risk: a population perspectivePeter W F Wilson
Cardiology Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30306 2636, USA
Am J Med 121:S15-20. 2008....
- Prediction of incident diabetes mellitus in middle-aged adults: the Framingham Offspring StudyPeter W F Wilson
Emory Program in Cardiovascular Outcomes Research and Epidemiology, Emory University School of Medicine, Atlanta, GA 30306, USA
Arch Intern Med 167:1068-74. 2007..Prediction rules for type 2 diabetes mellitus (T2DM) have been developed, but we lack consensus for the most effective approach...
- Hemostatic markers of endothelial dysfunction and risk of incident type 2 diabetes: the Framingham Offspring StudyJames B Meigs
General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA
Diabetes 55:530-7. 2006..09-1.77). We conclude that in this community-based sample, plasma markers of endothelial dysfunction increased risk of incident diabetes independent of other diabetes risk factors including obesity, insulin resistance, and inflammation...
- Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring StudiesJames B Meigs
Department of Medicine, General Medicine Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
Diabetes 52:2160-7. 2003..S. By any criteria, subjects with the metabolic syndrome are more insulin resistant and at increased predicted risk for CHD versus those without the metabolic syndrome...
- Prediction of first events of coronary heart disease and stroke with consideration of adiposityPeter W F Wilson
EPICORE, Emory University School of Medicine, Atlanta, GA 30306, USA
Circulation 118:124-30. 2008..Previous reports have focused on traditional cardiovascular risk factors; less information has been available on the role of overweight and obesity...
- PAI-1 Gene 4G/5G polymorphism and risk of type 2 diabetes in a population-based sampleJames B Meigs
General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Obesity (Silver Spring) 14:753-8. 2006..Elevated PAI-1 levels may be associated with an increased risk for diabetes as a marker for underlying endothelial dysfunction rather than by a direct effect of genetically mediated elevated levels...
- Insulin therapy in acute coronary syndromes: an appraisal of completed and ongoing randomised trials with important clinical end pointsAbhinav Goyal
Department of Epidemiology, Emory Rollins School of Public Health, Atlanta, GA, USA
Diab Vasc Dis Res 5:276-84. 2008....
- Risk scores for prediction of coronary heart disease: an updatePeter W F Wilson
Division of Cardiology, Emory University School of Medicine, EPICORE, Suite 1 North, 1256 Briarcliff Road, Atlanta, GA 30306, USA
Endocrinol Metab Clin North Am 38:33-44. 2009....
- Serum resistin concentrations and risk of new onset heart failure in older persons: the health, aging, and body composition (Health ABC) studyJaved Butler
Emory University, Atlanta GA, USA
Arterioscler Thromb Vasc Biol 29:1144-9. 2009..We investigated the association of serum resistin concentrations with risk for incident heart failure (HF) in humans...
- Low-cost strategies to predict cardiovascular diseasePeter W F Wilson
Emory University, Atlanta, GA 30306, USA
Nat Clin Pract Cardiovasc Med 5:518-9. 2008..Strategies such as these might enhance screening and prevention programs but require validation. Testing the usefulness of low-cost prediction models in developing regions is the next logical step in carrying this concept forward...
- Attained educational level and incident atherothrombotic events in low- and middle-income compared with high-income countriesAbhinav Goyal
Emory Rollins School of Public Health, 1518 Clifton Road NE, Atlanta, GA 30322, USA
Circulation 122:1167-75. 2010..However, most of these studies have been conducted in high-income countries (HICs) and lack representation from low- and middle-income countries (LMICs), which bear >80% of the global burden of cardiovascular disease...
- Predictors of incident heart failure in a large insured population: a one million person-year follow-up studyAbhinav Goyal
Emory Rollins School of Public Health, 1518 Clifton Road NE, Atlanta, GA 30322, USA
Circ Heart Fail 3:698-705. 2010..Studies on the incidence and predictors of heart failure (HF) are often restricted to elderly persons or identify only inpatient cases...
- Diabetes care in black and white veterans in the southeastern U.SJennifer G Twombly
Division of Endocrinology and Metabolism, Emory University School of Medicine, Atlanta, Georgia, USA
Diabetes Care 33:958-63. 2010..We investigated whether there were differences in diabetes care in the Veterans Administration (VA), where health care access should be relatively uniform...
- Prediction of cardiovascular disease eventsPeter W F Wilson
Atlanta VAMC Epidemiology and Genetics Section, Emory Clinical Cardiovascular Research Institute, Atlanta, GA 30322, USA
Cardiol Clin 29:1-13. 2011..Performance criteria for risk estimation include discrimination, calibration, and reclassification, and newer heart disease risk factors and biomarkers can be evaluated in the context of existing risk estimation approaches...
- C-reactive protein and reclassification of cardiovascular risk in the Framingham Heart StudyPeter W F Wilson
EPICORE, Emory University School of Medicine, and the Atlanta VAMC Epidemiology and Genetics Section, Atlanta, GA 30306, USA
Circ Cardiovasc Qual Outcomes 1:92-7. 2008..The relationship of circulating levels of high-sensitivity C-reactive protein (CRP) with cardiovascular disease (CVD) risk, particularly with consideration of effects at intermediate levels of risk, has not been fully assessed...
- Improved near-term coronary artery disease risk classification with gated stress myocardial perfusion SPECTLeslee J Shaw
Emory University School of Medicine, Atlanta, Georgia, USA
JACC Cardiovasc Imaging 3:1139-48. 2010..We compared analytical approaches to estimate the added value of myocardial perfusion single-photon emission computed tomography (MPS) variables in estimating coronary artery disease (CAD) outcomes...
- Epidemiology of incident heart failure in a contemporary elderly cohort: the health, aging, and body composition studyAndreas Kalogeropoulos
Cardiology Division, Emory University Hospital, Emory University, 1365 Clifton Rd NE, Ste AT430, Atlanta, GA 30322, USA
Arch Intern Med 169:708-15. 2009..The race- and sex-specific epidemiology of incident heart failure (HF) among a contemporary elderly cohort are not well described...
- Validation of the health ABC heart failure model for incident heart failure risk prediction: the Cardiovascular Health StudyAndreas Kalogeropoulos
Department of Medicine, Division of Cardiology, Emory University, Atlanta, GA 30322, USA
Circ Heart Fail 3:495-502. 2010..The recently developed and internally validated Health ABC HF model uses 9 routinely available clinical variables to determine incident heart failure risk. In this study, we sought to externally validate the Health ABC HF model...
- Sleep-disordered breathing in the National Football LeagueThomas B Rice
Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Sleep 33:819-24. 2010..NFL players have a higher prevalence of hypertension, and we sought to determine the prevalence of SDB among players the NFL and the associations of SDB with anthropometric measures and cardiovascular risk factors...
- Obesity, diabetes, and risk of cardiovascular disease in the elderlyPeter W F Wilson
Department of Medicine, Boston University Medical School, Boston, MA 02118, USA
Am J Geriatr Cardiol 11:119-23,125. 2002..Trial data indicate that preventive measures benefit obese diabetics even more than nondiabetics...
- Glycemic status and incident heart failure in elderly without history of diabetes mellitus: the health, aging, and body composition studyAndreas Kalogeropoulos
Emory University, Atlanta, GA, USA
J Card Fail 15:593-9. 2009..It is unclear whether measures of glycemic status beyond fasting glucose (FG) levels improve incident heart failure (HF) prediction in patients without history of diabetes mellitus (DM)...
- A genome-wide scan for loci linked to plasma levels of glucose and HbA(1c) in a community-based sample of Caucasian pedigrees: The Framingham Offspring StudyJames B Meigs
General Internal Medicine and Clinical Epidemiology Units, General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
Diabetes 51:833-40. 2002....
- Associations of adiponectin, resistin, and tumor necrosis factor-alpha with insulin resistanceMarie France Hivert
Department of Medicine, Harvard Medical School, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 93:3165-72. 2008..Adipose tissue-derived adipokines may contribute to insulin resistance...
- Optimal vitamin D status attenuates the age-associated increase in systolic blood pressure in white Americans: results from the third National Health and Nutrition Examination SurveySuzanne E Judd
Nutrition and Health Sciences Program, Graduate Division of Biological and Biomedical Sciences and Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Am J Clin Nutr 87:136-41. 2008..The prevalences of both hypertension and vitamin D insufficiency are high in the United States. Recent clinical trials and animal studies have suggested that vitamin D insufficiency may be associated with elevated blood pressure...
- Comparison of prognostic usefulness of coronary artery calcium in men versus women (results from a meta- and pooled analysis estimating all-cause mortality and coronary heart disease death or myocardial infarction)Antonio Bellasi
Emory University School of Medicine, Atlanta, Georgia, USA
Am J Cardiol 100:409-14. 2007..66), suggesting an equivalent ability to risk stratify by gender. In conclusion, this meta- and pooled analysis revealed that CAC screening is equally accurate in stratifying risk in women and men...
- Genotype score in addition to common risk factors for prediction of type 2 diabetesJames B Meigs
General Medicine Division, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
N Engl J Med 359:2208-19. 2008..We tested the hypothesis that knowledge of these loci allows better prediction of risk than knowledge of common phenotypic risk factors alone...
- Estradiol, testosterone, and the risk for hip fractures in elderly men from the Framingham StudyShreyasee Amin
Boston University Clinical Epidemiology Research and Training Unit, Department of Medicine, Boston University School of Medicine, Boston, Mass, USA
Am J Med 119:426-33. 2006..We examined whether low estradiol increases the risk for future hip fracture among men and explored whether testosterone levels influence this risk...
- Obesity: why be concerned?W Virgil Brown
Department of Internal Medicine, Emory University School of Medicine, Atlanta, Georgia 30033, USA
Am J Med 122:S4-11. 2009....
- Sex and age differences in lipoprotein subclasses measured by nuclear magnetic resonance spectroscopy: the Framingham StudyDavid S Freedman
Division of Nutrition and Physical Activity, CDC, Atlanta, GA, USA
Clin Chem 50:1189-200. 2004..We examined whether this differential CHD risk might, in part, be attributable to the sizes of lipoprotein particles or concentrations of lipoprotein subclasses...
- Cardiovascular risk assessment--where are we going?Peter W F Wilson
American Society of Preventive Cardiology
Prev Cardiol 11:183-4. 2008
- Lifetime risk of cardiovascular disease among individuals with and without diabetes stratified by obesity status in the Framingham heart studyCaroline S Fox
National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts, USA
Diabetes Care 31:1582-4. 2008..We assessed the lifetime risk of cardiovascular disease (CVD) among individuals with and without obesity and diabetes...
- Use of alternative thresholds defining insulin resistance to predict incident type 2 diabetes mellitus and cardiovascular diseaseMartin K Rutter
Cardiovascular Research Group, Division of Cardiovascular and Endocrine Sciences, University of Manchester, and The Manchester Diabetes Centre, Manchester Royal Infirmary, Manchester, United Kingdom
Circulation 117:1003-9. 2008....
- BMI vs. waist circumference for identifying vascular riskMatthew S Freiberg
Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Obesity (Silver Spring) 16:463-9. 2008..0 and 34.9 kg/m(2). We investigated the relative contributions of BMI and WC toward identifying risk of adverse vascular events in a community-based sample...
- The significant effect of diabetes duration on coronary heart disease mortality: the Framingham Heart StudyCaroline S Fox
National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts 01702, USA
Diabetes Care 27:704-8. 2004..We hypothesized that duration of diabetes is an important predictor of incident CHD among people with diabetes...
- C-reactive protein, inflammatory conditions, and cardiovascular disease riskRavi Dhingra
National Heart Lung and Blood Institute s NHBLI Framingham Heart Study, Framingham, Mass 01702 5827, USA
Am J Med 120:1054-62. 2007..It is uncertain to what extent high C-reactive protein (CRP) concentrations reflect the presence of inflammatory conditions in the community...
- Differences in cardiovascular disease mortality associated with body mass between Black and White personsJill E Abell
Medical University of South Carolina, Charleston, SC 29401, USA
Am J Public Health 98:63-6. 2008..91 (95% CI=0.77, 1.05), respectively. The results suggest that obesity is an independent risk factor in White people, and additional study of body size and disease progression is necessary in the assessment of racial disparities...
- A likely explanation for the J-curve of blood pressure cardiovascular riskWilliam B Kannel
Boston University School of Medicine Framingham Heart Study, Framingham, Massachusetts 01702 5827, USA
Am J Cardiol 94:380-4. 2004..Patients with this condition of isolated systolic hypertension have been shown to benefit from antihypertensive treatment...
- Carbohydrate nutrition, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring CohortNicola M McKeown
Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
Diabetes Care 27:538-46. 2004..The aim of this study was to examine the relation between carbohydrate-related dietary factors, insulin resistance, and the prevalence of the metabolic syndrome in the Framingham Offspring Cohort...
- Insulin resistance syndrome and the prothrombotic state: a Framingham perspectivePeter W F Wilson
Endocr Pract 9:50-2. 2003
- The metabolic syndrome: practical guide to origins and treatment: Part IPeter W F Wilson
Framingham Heart Study of the National Heart, Blood, and Lung Institute, Boston, Mass, USA
Circulation 108:1422-4. 2003
- Whole-grain intake is favorably associated with metabolic risk factors for type 2 diabetes and cardiovascular disease in the Framingham Offspring StudyNicola M McKeown
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
Am J Clin Nutr 76:390-8. 2002..The influence of whole grains on cardiovascular disease risk may be mediated through multiple pathways, eg, a reduction in blood lipids and blood pressure, an enhancement of insulin sensitivity, and an improvement in blood glucose control...
- Overweight and obesity as determinants of cardiovascular risk: the Framingham experiencePeter W F Wilson
Boston University School of Medicine, 715 Albany St, Evans 204, Boston, MA 02118, USA
Arch Intern Med 162:1867-72. 2002..To our knowledge, no single investigation concerning the long-term effects of overweight status on the risk for hypertension, hypercholesterolemia, diabetes mellitus, and cardiovascular sequelae has been reported...
- Plasma natriuretic peptides for community screening for left ventricular hypertrophy and systolic dysfunction: the Framingham heart studyRamachandran S Vasan
National Heart, Lung, and Blood Institute s Framingham Heart Study, 73 Mt Wayte Ave, Suite 2, Framingham, MA 01702, USA
JAMA 288:1252-9. 2002..Prior studies were limited by small sample sizes and selection bias and none compared the diagnostic performance of these peptides in men and women...
- Obesity and systemic oxidative stress: clinical correlates of oxidative stress in the Framingham StudyJohn F Keaney
Evans Memorial Department of Medicine, Boston University School of Medicine, Whitaker Cardiovascular Institute, 715 Albany St, Rm W507, Boston, MA 02118, USA
Arterioscler Thromb Vasc Biol 23:434-9. 2003..Thus, it has been difficult to evaluate the relative contribution of each cardiovascular risk factor to systemic oxidative stress and to determine whether such risk factors act independently and are applicable to the general population...
- Inflammatory markers and risk of heart failure in elderly subjects without prior myocardial infarction: the Framingham Heart StudyRamachandran S Vasan
Framingham Heart Study, Framingham, Mass 01702 5803, USA
Circulation 107:1486-91. 2003..It is unclear whether cytokine levels can predict the incidence of CHF in asymptomatic individuals...
- Impact of obesity on plasma natriuretic peptide levelsThomas J Wang
Framingham Heart Study, Framingham, Mass 01702, USA
Circulation 109:594-600. 2004..The natriuretic peptides are important regulators of sodium homeostasis and neurohormonal activation, raising the possibility that obese individuals have an impaired natriuretic peptide response...
- American College of Endocrinology position statement on the insulin resistance syndromeDaniel Einhorn
American College of Endocrinology
Endocr Pract 9:237-52. 2003
- Risk stratification of obesity as a coronary risk factorWilliam B Kannel
Framingham Study, Boston University School of Medicine, Framingham, Massachusetts, USA
Am J Cardiol 90:697-701. 2002..Global risk assessment can identify high-risk overweight candidates for CHD who most urgently need correction of associated risk factors, as well as sustained weight reduction...
- Elevated remnant-like particle cholesterol and triglyceride levels in diabetic men and women in the Framingham Offspring StudyErnst J Schaefer
Lipid Research Laboratory, Division of Endocrinology, Diabetes, Metabolism, and Molecular Medicine, New England Medical Center, Boston, Massachusetts 02111, USA
Diabetes Care 25:989-94. 2002..We hypothesized that diabetic patients would have higher remnant levels than nondiabetic patients...
- A coronary heart disease risk score based on patient-reported informationArch G Mainous
Department of Family Medicine, Medical University of South Carolina, Charleston, South Carolina, USA
Am J Cardiol 99:1236-41. 2007..69, p = 0.01). In conclusion, the Personal HEART score identifies 10-year risk for CHD based on self-report data, is similar in predictive ability to the FRS and European SCORE, and has the potential for easy self-assessment...
- Cardiac rehabilitation and getting to lipid goalsPeter W F Wilson
J Cardiopulm Rehabil 25:264-5. 2005
- Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitusPeter W F Wilson
The NHLBI s Framingham Heart Study, Framingham, Massachusetts, USA
Circulation 112:3066-72. 2005..The objective was to investigate risk for CVD, CHD, and T2DM according to metabolic syndrome traits...
- C-reactive protein and risk of cardiovascular disease in men and women from the Framingham Heart StudyPeter W F Wilson
General Clinical Research Center, Medical University of South Carolina, Charleston 29425, USA
Arch Intern Med 165:2473-8. 2005..Determination of C-reactive protein (CRP) level has been suggested to improve cardiovascular disease (CVD) risk assessment. This study examines the utility of CRP levels to assess CVD risk in a community setting...
- Heritability and correlates of intercellular adhesion molecule-1 in the Framingham Offspring StudyJohn F Keaney
Evans Memorial Department of Medicine, Boston University School of Medicine, Massachusetts 02118, USA
J Am Coll Cardiol 44:168-73. 2004..We sought to determine the clinical factors and heritability associated with inflammation measured as circulating levels of soluble-intercellular adhesion molecule-1 (sICAM-1) in a community-based cohort...
- CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: ability of inflammatory markers to predict disease in asymptomatic patients: a background paperPeter W F Wilson
Circulation 110:e568-71. 2004....
- Clinical trial issues in weight-loss therapyManesh R Patel
Duke University Medical Center, Durham, NC 27708, USA
Am Heart J 151:633-42. 2006..Effective obesity therapies also have the potential for off-label use and unintended consequences...
- The insulin gene variable number tandem repeat and risk of type 2 diabetes in a population-based sample of families and unrelated men and womenJames B Meigs
General Medicine Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
J Clin Endocrinol Metab 90:1137-43. 2005..These data support the hypothesis that the INS VNTR is a genetic risk factor for type 2 diabetes, with the TT genotype accounting for about 6.6% of cases in the FHS population...
- Contribution of clinical correlates and 13 C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein levelSekar Kathiresan
Framingham Heart Study, Framingham, MA 01702 5827, USA
Circulation 113:1415-23. 2006..Serum C-reactive protein (CRP) level is a heritable complex trait that predicts incident cardiovascular disease. We investigated the clinical and genetic sources of interindividual variability in serum CRP...
- Estimating the risk for atherothrombosis: are current approaches sufficient?Peter W F Wilson
General Clinical Research Center, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Eur J Cardiovasc Prev Rehabil 12:427-32. 2005....
- C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring StudyMartin K Rutter
Countess of Chester Hospital, Chester, UK
Circulation 110:380-5. 2004..Inflammation (assessed by C-reactive protein [CRP]) and the metabolic syndrome (MetS) are associated with cardiovascular disease (CVD), but population-based data are limited...
- Assessing coronary heart disease risk with traditional and novel risk factorsPeter W F Wilson
Department of Endocrinology, Diabetes, and Medical Geriatrics, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Clin Cardiol 27:III7-11. 2004..Assessment of global risk is particularly important in lipid management, as the LDL-C target goals are determined by risk category...
- Impact of insulin resistance on risk of type 2 diabetes and cardiovascular disease in people with metabolic syndromeJames B Meigs
Harvard Medical School and the General Medicine Division, Massachusetts General Hospital, 50 Staniford St, 9th Floor, Boston, MA 02114, USA
Diabetes Care 30:1219-25. 2007..Metabolic syndrome increases the risk for type 2 diabetes and cardiovascular disease (CVD) and may be associated with insulin resistance...
- Magnesium intake is related to improved insulin homeostasis in the framingham offspring cohortMarcella E Rumawas
Nutritional Epidemiology Program, JM USDA HNRC at Tufts University, Boston, MA 02111 1524, USA
J Am Coll Nutr 25:486-92. 2006..Higher dietary intake of magnesium may protect against development of type 2 diabetes. The aim of this study was to examine the association between dietary magnesium intake and metabolic risk factors for diabetes...
- Should C-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?Paul M Ridker
Donald W Reynolds Center for Cardiovascular Research, Boston, Mass, USA
Circulation 109:2818-25. 2004..Toward this end, we believe experts in the fields of epidemiology, prevention, vascular biology, and clinical cardiology should be convened to begin discussing the merits of this proposal...
- Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular diseaseJames B Meigs
General Medicine Division, Massachusetts General Hospital, 50 Staniford Street, 9th Floor, Boston, MA 02114, USA
J Clin Endocrinol Metab 91:2906-12. 2006..Metabolic risk conferred by adiposity may be due to associated risk factor clustering...
- Concept and usefulness of cardiovascular risk profilesWilliam B Kannel
National Heart, Lung, and Blood Institute s Framingham Study, National Institutes of Health, Boston University School of Medicine, Framingham, Mass 01702, USA
Am Heart J 148:16-26. 2004..Multivariable risk stratification is now recognized as essential in efficiently identifying likely candidates for CVD and quantifying the hazard...
- Relative importance of borderline and elevated levels of coronary heart disease risk factorsRamachandran S Vasan
Framingham Heart Study, Framingham, Massachusetts 01702 5803, USA
Ann Intern Med 142:393-402. 2005..Clinical trials indicate that a sizable proportion of adults have multiple borderline coronary risk factors and may benefit from treatment...
- 34th Bethesda Conference: Task force #1--Identification of coronary heart disease risk: is there a detection gap?Richard C Pasternak
Preventive Cardiology and Cardiac Rehabilitation, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114 2620, USA
J Am Coll Cardiol 41:1863-74. 2003
- The ankle-brachial index in the elderly and risk of stroke, coronary disease, and death: the Framingham StudyJoanne M Murabito
National Heart, Lung, and Blood Institute s Framingham Heart Study, National Institutes of Health, Framingham, MA 01702 5827, USA
Arch Intern Med 163:1939-42. 2003..Limited data exist regarding the relation between a low ABI and stroke. We sought to examine the relation between a low ABI and stroke, coronary heart disease, and death in the elderly...
- Framingham and European risk algorithms: implications for African AmericansPeter W F Wilson
General Clinical Research Center, Medical University of South Carolina, Charleston, South Carolina, USA
Rev Cardiovasc Med 5:S34-41. 2004..Estimation of risk for cardiovascular events is a dynamic field, and current approaches will likely be modified as newer information is obtained...
- Coronary artery calcification in type 2 diabetes and insulin resistance: the framingham offspring studyJames B Meigs
General Medicine Division and Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
Diabetes Care 25:1313-9. 2002....
- Obesity modulates the association among APOE genotype, insulin, and glucose in menRoberto Elosua
Nutrition and Genomics Laboratory and Lipid Metabolism Laboratory, Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
Obes Res 11:1502-8. 2003..Obesity, insulin resistance, and apolipoprotein E (APOE) genotype have all been associated with coronary heart disease. We examined the interaction between obesity and APOE genotype in determining fasting insulin and glucose levels...
- Clinical utility of different lipid measures for prediction of coronary heart disease in men and womenErik Ingelsson
Framingham Heart Study, 73 Mount Wayte Ave, Suite 2, Framingham, MA 01702 5803
JAMA 298:776-85. 2007..Evidence is conflicting regarding the performance of apolipoproteins vs traditional lipids for predicting coronary heart disease (CHD) risk...
- Association between obesity and a prothrombotic state: the Framingham Offspring StudyGuido A Rosito
Hospital Clinicas, Porto Alegre, Brazil
Thromb Haemost 91:683-9. 2004..The association between increased body mass index and waist-to-hip ratio and prothrombotic factors and impaired fibrinolysis suggests that obesity is a risk factor whose effect is mediated in part by a prothrombotic state...
- Relations of serum aldosterone to cardiac structure: gender-related differences in the Framingham Heart StudyRamachandran S Vasan
National Heart, Lung, and Blood Institute s Framingham Heart Study, Bethesda, MD, USA
Hypertension 43:957-62. 2004..Additional investigations are warranted to confirm these findings...
- CETP genes, metabolic effects, and coronary disease riskPeter W F Wilson
JAMA 299:2795-6. 2008
- Accuracy of offspring reports of parental cardiovascular disease history: the Framingham Offspring StudyJoanne M Murabito
National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, Massachusetts 01702 5827, USA
Ann Intern Med 140:434-40. 2004..Family history is used to infer the risk for heart disease; however, little is known about the accuracy of family history reports...
- Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham StudyZaldy Sy Tan
Division on Aging, Harvard Medical School, Boston, MA, USA
Arch Intern Med 163:1053-7. 2003..We examined the impact of baseline and lifetime plasma total cholesterol levels averaged across many years on the risk for AD in a large, population-based cohort...
- Anticardiolipin antibodies and risk of ischemic stroke and transient ischemic attack: the Framingham cohort and offspring studyVallabh Janardhan
Department of Neurology, Boston University, Boston, Mass, USA
Stroke 35:736-41. 2004..Prior cohort studies included only selected subjects, mostly men. We related serum concentrations of aCLs to incident first ischemic stroke/TIA among men and women in the Framingham Heart Study cohort and offspring...
- Increased small low-density lipoprotein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart StudySekar Kathiresan
The National Heart, Lung, and Blood Institute s Framingham Heart Study, Framingham, MA, USA
Circulation 113:20-9. 2006..However, the atherogenic potential of LDL may depend on the number and size of LDL particles in addition to the cholesterol content of LDL...
- Development of appropriate coronary heart disease risk prediction models in HIV-infected patientsMorris Schambelan
Circulation 118:e48-53. 2008
- Inflammatory markers and improving CHD risk assessmentPeter Wilson; Fiscal Year: 2004..abstract_text> ..