Patricia W Lin

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi request reprint Necrotising enterocolitis
    Patricia W Lin
    Division of Neonatal Perinatal Medicine, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    Lancet 368:1271-83. 2006
  2. doi request reprint Necrotizing enterocolitis: recent scientific advances in pathophysiology and prevention
    Patricia W Lin
    Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA
    Semin Perinatol 32:70-82. 2008
  3. pmc The probiotic Lactobacillus GG may augment intestinal host defense by regulating apoptosis and promoting cytoprotective responses in the developing murine gut
    Patricia W Lin
    Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Pediatr Res 64:511-6. 2008
  4. pmc Lactobacillus rhamnosus blocks inflammatory signaling in vivo via reactive oxygen species generation
    Patricia W Lin
    Division of Neonatal Perinatal Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Free Radic Biol Med 47:1205-11. 2009
  5. pmc Commensal Escherichia coli reduces epithelial apoptosis through IFN-alphaA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine
    Julie Mirpuri
    Division of Neonatal Perinatal Medicine, Department of Pediatrics, Emory University School of Medicine, Spelman College, Atlanta, GA 30322, USA
    J Immunol 184:7186-95. 2010
  6. pmc Developmental biology of gut-probiotic interaction
    Ravi Mangal Patel
    Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA
    Gut Microbes 1:186-95. 2010
  7. pmc Probiotic bacteria induce maturation of intestinal claudin 3 expression and barrier function
    Ravi M Patel
    Division of Neonatology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia
    Am J Pathol 180:626-35. 2012

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Necrotising enterocolitis
    Patricia W Lin
    Division of Neonatal Perinatal Medicine, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA
    Lancet 368:1271-83. 2006
    ....
  2. doi request reprint Necrotizing enterocolitis: recent scientific advances in pathophysiology and prevention
    Patricia W Lin
    Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA
    Semin Perinatol 32:70-82. 2008
    ..Hopefully, future studies aimed at understanding premature intestinal defenses, commensal or probiotic bacterial influences, and possible genetic predisposition will lead to the improvement of prevention and treatment strategies...
  3. pmc The probiotic Lactobacillus GG may augment intestinal host defense by regulating apoptosis and promoting cytoprotective responses in the developing murine gut
    Patricia W Lin
    Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Pediatr Res 64:511-6. 2008
    ..Because apoptosis may be a precursor to NEC, understanding the mechanism behind probiotic modulation of apoptotic pathways may allow for development of more specifically targeted therapies or preventive strategies in the future...
  4. pmc Lactobacillus rhamnosus blocks inflammatory signaling in vivo via reactive oxygen species generation
    Patricia W Lin
    Division of Neonatal Perinatal Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    Free Radic Biol Med 47:1205-11. 2009
    ....
  5. pmc Commensal Escherichia coli reduces epithelial apoptosis through IFN-alphaA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine
    Julie Mirpuri
    Division of Neonatal Perinatal Medicine, Department of Pediatrics, Emory University School of Medicine, Spelman College, Atlanta, GA 30322, USA
    J Immunol 184:7186-95. 2010
    ....
  6. pmc Developmental biology of gut-probiotic interaction
    Ravi Mangal Patel
    Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA
    Gut Microbes 1:186-95. 2010
    ..Improved knowledge of gut-probiotic interaction in developing epithelia will allow for a better understanding of how probiotics exert their beneficial effects and help guide their therapeutic use...
  7. pmc Probiotic bacteria induce maturation of intestinal claudin 3 expression and barrier function
    Ravi M Patel
    Division of Neonatology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia
    Am J Pathol 180:626-35. 2012
    ..Probiotics may prevent intestinal inflammatory diseases by regulating intestinal tight junction protein expression and barrier function. The use of heat-killed probiotics may provide therapeutic benefit while minimizing adverse effects...

Research Grants2

  1. Paneth Cell Cryptdins in Innate Intestinal Host Defense
    Patricia Lin; Fiscal Year: 2007
    ..abstract_text> ..
  2. Bacterial Colonization and Development of Innate Intestinal Host Defense
    Patricia Lin; Fiscal Year: 2008
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