Milton W Datta

Summary

Affiliation: Emory University
Country: USA

Publications

  1. pmc Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway
    Milton W Datta
    Department of Pathology, Emory University, Atlanta, GA 30322, USA
    Mol Cancer 5:9. 2006
  2. pmc An informatics model for tissue banks--lessons learned from the Cooperative Prostate Cancer Tissue Resource
    Ashokkumar A Patel
    Department of Pathology, Center for Pathology Informatics, Benedum Oncology Informatics Center, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Cancer 6:120. 2006
  3. pmc Nox1 expression determines cellular reactive oxygen and modulates c-fos-induced growth factor, interleukin-8, and Cav-1
    Rebecca S Arnold
    Department of Urology, Winship Cancer Institute, Emory University School of Medicine, 1365 Clifton Rd, Building B, Atlanta, GA 30322, USA
    Am J Pathol 171:2021-32. 2007
  4. ncbi request reprint Expression analysis of kidney-specific cadherin in a wide spectrum of traditional and newly recognized renal epithelial neoplasms: diagnostic and histogenetic implications
    Adam Kuehn
    Department of Pathology, Emory University Hospital, Atlanta, GA, USA
    Am J Surg Pathol 31:1528-33. 2007
  5. pmc The development of common data elements for a multi-institute prostate cancer tissue bank: the Cooperative Prostate Cancer Tissue Resource (CPCTR) experience
    Ashokkumar A Patel
    Department of Pathology, Center for Pathology Informatics, Benedum Oncology Informatics Center, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Cancer 5:108. 2005
  6. pmc Frequency and determinants of disagreement and error in gleason scores: a population-based study of prostate cancer
    Michael Goodman
    Department of Epidemiology, Emory University Rollins School of Public Health, 1518 Clifton Road, NE Atlanta, GA 30322, USA
    Prostate 72:1389-98. 2012
  7. ncbi request reprint Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells
    Pengbo Liu
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Res 66:4011-9. 2006
  8. ncbi request reprint Current trends in molecular classification of adult renal tumors
    Andrew N Young
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
    Urology 67:873-80. 2006
  9. ncbi request reprint Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model
    Chia Ling Hsieh
    Molecular Urology and Therapeutic Program, Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Prostate 67:685-91. 2007
  10. ncbi request reprint A simple inexpensive method for the production of tissue microarrays from needle biopsy specimens: examples with prostate cancer
    Milton W Datta
    Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Appl Immunohistochem Mol Morphol 13:96-103. 2005

Collaborators

Detail Information

Publications27

  1. pmc Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway
    Milton W Datta
    Department of Pathology, Emory University, Atlanta, GA 30322, USA
    Mol Cancer 5:9. 2006
    ..Previously we have linked Perlecan to Hedgehog signaling in Drosophila. More recently, we have demonstrated the importance of Hedgehog signaling in humans for advanced prostate cancer...
  2. pmc An informatics model for tissue banks--lessons learned from the Cooperative Prostate Cancer Tissue Resource
    Ashokkumar A Patel
    Department of Pathology, Center for Pathology Informatics, Benedum Oncology Informatics Center, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Cancer 6:120. 2006
    ..Here we describe the CPCTR information management system architecture, common data element (CDE) development, query interfaces, data curation, and quality control...
  3. pmc Nox1 expression determines cellular reactive oxygen and modulates c-fos-induced growth factor, interleukin-8, and Cav-1
    Rebecca S Arnold
    Department of Urology, Winship Cancer Institute, Emory University School of Medicine, 1365 Clifton Rd, Building B, Atlanta, GA 30322, USA
    Am J Pathol 171:2021-32. 2007
    ..0001). These studies indicate that Nox1 overexpression may function as a reversible signal for cellular proliferation with relevance for a common human tumor...
  4. ncbi request reprint Expression analysis of kidney-specific cadherin in a wide spectrum of traditional and newly recognized renal epithelial neoplasms: diagnostic and histogenetic implications
    Adam Kuehn
    Department of Pathology, Emory University Hospital, Atlanta, GA, USA
    Am J Surg Pathol 31:1528-33. 2007
    ....
  5. pmc The development of common data elements for a multi-institute prostate cancer tissue bank: the Cooperative Prostate Cancer Tissue Resource (CPCTR) experience
    Ashokkumar A Patel
    Department of Pathology, Center for Pathology Informatics, Benedum Oncology Informatics Center, University of Pittsburgh, Pittsburgh, PA, USA
    BMC Cancer 5:108. 2005
    ..To facilitate this effort, it was critical to arrive at agreed upon common data elements (CDEs) that could be used to collect demographic, pathologic, treatment and clinical outcome data...
  6. pmc Frequency and determinants of disagreement and error in gleason scores: a population-based study of prostate cancer
    Michael Goodman
    Department of Epidemiology, Emory University Rollins School of Public Health, 1518 Clifton Road, NE Atlanta, GA 30322, USA
    Prostate 72:1389-98. 2012
    ..To examine factors that affect accuracy and reliability of prostate cancer grade we compared Gleason scores documented in pathology reports and those assigned by urologic pathologists in a population-based study...
  7. ncbi request reprint Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells
    Pengbo Liu
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cancer Res 66:4011-9. 2006
    ..Stable transfection of SOX4 into nontransformed prostate cells enabled colony formation in soft agar, suggesting that, in the proper cellular context, SOX4 can be a transforming oncogene...
  8. ncbi request reprint Current trends in molecular classification of adult renal tumors
    Andrew N Young
    Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
    Urology 67:873-80. 2006
  9. ncbi request reprint Non-invasive bioluminescent detection of prostate cancer growth and metastasis in a bigenic transgenic mouse model
    Chia Ling Hsieh
    Molecular Urology and Therapeutic Program, Department of Urology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Prostate 67:685-91. 2007
    ....
  10. ncbi request reprint A simple inexpensive method for the production of tissue microarrays from needle biopsy specimens: examples with prostate cancer
    Milton W Datta
    Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Appl Immunohistochem Mol Morphol 13:96-103. 2005
    ..This process can be extended to any type of needle biopsy specimen, increasing the number of studies and potential use of these tissues as a practical reality...
  11. pmc Cross-species global and subset gene expression profiling identifies genes involved in prostate cancer response to selenium
    Michael Schlicht
    Department of Pathology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA
    BMC Genomics 5:58. 2004
    ..This method is made possible through the use of highly controlled spotted cDNA slide production and the use of comparative bioinformatics databases without the use of cross-species slide hybridizations...
  12. ncbi request reprint The cooperative prostate cancer tissue resource: a specimen and data resource for cancer researchers
    Jonathan Melamed
    Department of Pathology, New York University School of Medicine, New York, New York 10016, USA
    Clin Cancer Res 10:4614-21. 2004
    ..This communication describes the CPCTR to investigators interested in obtaining prostate cancer tissue samples...
  13. ncbi request reprint Giant multilocular cystadenoma of the prostate responsive to GnRH antagonists
    Milton W Datta
    Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Urology 61:225. 2003
    ..The patient was stable without biochemical or radiologic evidence of progression during the last 2.5 years. This result offers a new treatment option for patients with this rare tumor...
  14. ncbi request reprint p27 and cyclin E/D2 associations in testicular germ cell tumors: implications for tumorigenesis
    Robyn Kukoski
    Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Appl Immunohistochem Mol Morphol 11:138-43. 2003
    ....
  15. ncbi request reprint Expression of p27 and VHL in renal tumors
    Vladimir Osipov
    Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Appl Immunohistochem Mol Morphol 10:344-50. 2002
    ..These findings suggest a role for p27 in the development of various types of renal tumors...
  16. pmc ChromSorter PC: a database of chromosomal regions associated with human prostate cancer
    Ann Etim
    Department of Pathology, Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    BMC Genomics 5:27. 2004
    ..The input material was based on a broad literature search with subsequent hand annotation of information relevant to prostate cancer...
  17. pmc Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling
    Pilar Sanchez
    Skirball Institute and Department of Cell Biology, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 101:12561-6. 2004
    ..Our data demonstrate the dependence of prostate cancer on SHH-GLI function and suggest a novel therapeutic approach...
  18. pmc A simple computer program for calculating PSA recurrence in prostate cancer patients
    Zhongyue Liao
    Medical College of Wisconsin, Milwaukee, WI, 53226, U, S, A
    BMC Urol 4:8. 2004
    ..This method needs to be simple and reproducible, and based on known aspects of PSA biology...
  19. ncbi request reprint The role of tissue microarrays in prostate cancer biomarker discovery
    Milton W Datta
    Hospital Pathology Associates, Abbott Northwestern Hospital, University of Minnesota, Minneapolis, MN 55407, USA
    Adv Anat Pathol 14:408-18. 2007
    ..The processes used here can be applied to any tumor type to improve patient diagnosis, prognosis, and treatment response prediction...
  20. pmc Use of a three-color cDNA microarray platform to measure and control support-bound probe for improved data quality and reproducibility
    Martin J Hessner
    The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, The Medical College of Wisconsin and Children s Hospital of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Nucleic Acids Res 31:e60. 2003
    ..Collectively, this strategy will improve microarray data and increase its utility as a sensitive screening tool...
  21. ncbi request reprint Further characterization of the muscle layers and lamina propria of the urinary bladder by systematic histologic mapping: implications for pathologic staging of invasive urothelial carcinoma
    Gladell P Paner
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am J Surg Pathol 31:1420-9. 2007
    ....
  22. ncbi request reprint Intrahepatic portal hypertension secondary to metastatic carcinoma of the prostate
    Tan Attila
    Medical College of Wisconsin, 9200 W WisconsinAve, Milwaukee, WI, USA
    WMJ 106:34-6. 2007
    ..We report a case of a patient with symptomatic portal hypertension due to diffuse metastatic prostate carcinoma infiltration of liver parenchyma that was not appreciated with routine imaging...
  23. ncbi request reprint Prostate cancer with low PSA levels
    Milton W Datta
    N Engl J Med 351:1802-3. 2004
  24. ncbi request reprint Perlecan signaling: helping hedgehog stimulate prostate cancer growth
    Sumana Datta
    Department of Biochemistry and Biophysics, MS 2128, Texas A and M University, College Station, TX 77843 2128, United States
    Int J Biochem Cell Biol 38:1855-61. 2006
    ..Inhibitors of Perlecan function at either the protein or glycan level would be ideal drug candidates for anti-cancer therapies...
  25. ncbi request reprint Genetic mapping and characterization of the bleeding disorder in the fawn-hooded hypertensive rat
    Yvonne H Datta
    Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Thromb Haemost 89:1031-42. 2003
    ..Therefore positional cloning of the gene responsible for the bleeding disorder in the FHH rat will lead to new insights in platelet physiology, with implications for diagnosis and management of hemostatic and thrombotic disorders...
  26. pmc B.E.A.R. GeneInfo: a tool for identifying gene-related biomedical publications through user modifiable queries
    Guohui Zhou
    Department of Pathology and Bioinformatics Program, Medical College of Wisconsin, Milwaukee, WI, 53226, USA
    BMC Bioinformatics 5:46. 2004
    ..In these situations having a tool for searching the biomedical literature using the list of identified genes while simultaneously defining additional search terms would be useful...
  27. ncbi request reprint Prostate cancer in patients with screening serum prostate specific antigen values less than 4.0 ng/dl: results from the cooperative prostate cancer tissue resource
    Milton W Datta
    Departments of Pathology, New York University School of Medicine, New York, New York, USA
    J Urol 173:1546-51. 2005
    ..0 ng/ml). It is currently unclear whether these tumors are different from prostate cancer in patients with high PSA levels (greater than 4.0 ng/ml)...