Krishna Bhat

Summary

Affiliation: Emory University
Country: USA

Publications

  1. ncbi request reprint Sloppy paired acts as the downstream target of wingless in the Drosophila CNS and interaction between sloppy paired and gooseberry inhibits sloppy paired during neurogenesis
    K M Bhat
    Department of Cell Biology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA
    Development 127:655-65. 2000
  2. ncbi request reprint Upregulation of Mitimere and Nubbin acts through cyclin E to confer self-renewing asymmetric division potential to neural precursor cells
    Krishna Moorthi Bhat
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Development 131:1123-34. 2004
  3. ncbi request reprint frizzled and frizzled 2 play a partially redundant role in wingless signaling and have similar requirements to wingless in neurogenesis
    K M Bhat
    Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cell 95:1027-36. 1998
  4. pmc The posterior determinant gene nanos is required for the maintenance of the adult germline stem cells during Drosophila oogenesis
    K M Bhat
    Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Genetics 151:1479-92. 1999
  5. ncbi request reprint Segment polarity genes in neuroblast formation and identity specification during Drosophila neurogenesis
    K M Bhat
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Bioessays 21:472-85. 1999
  6. ncbi request reprint Cell division genes promote asymmetric interaction between Numb and Notch in the Drosophila CNS
    P Wai
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Development 126:2759-70. 1999
  7. ncbi request reprint Slit signaling promotes the terminal asymmetric division of neural precursor cells in the Drosophila CNS
    B Mehta
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Development 128:3161-8. 2001
  8. ncbi request reprint Establishment of stem cell identity in the Drosophila germline
    K M Bhat
    Department of Molecular Biology, Princeton University, New Jersey, USA
    Dev Dyn 210:371-82. 1997
  9. ncbi request reprint Cell-cell signaling during neurogenesis: some answers and many questions
    K M Bhat
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Int J Dev Biol 42:127-39. 1998
  10. ncbi request reprint Generating asymmetry: with and without self-renewal
    Ivana Gaziova
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch School of Medicine, Galveston, Texas 77555, USA
    Prog Mol Subcell Biol 45:143-78. 2007

Collaborators

  • Ivana Gaziova
  • Tanuja T Merianda
  • Barry Yedvobnick
  • Baragur V Shyamala
  • B Mehta
  • P Wai
  • Vandana Botta
  • Nathan Mortimer
  • Jonathan Opraseuth
  • Anumeha Kumar
  • Padmashree Chaudhury
  • B Truong

Detail Information

Publications16

  1. ncbi request reprint Sloppy paired acts as the downstream target of wingless in the Drosophila CNS and interaction between sloppy paired and gooseberry inhibits sloppy paired during neurogenesis
    K M Bhat
    Department of Cell Biology, Emory University School of Medicine, Emory University, Atlanta, GA 30322, USA
    Development 127:655-65. 2000
    ..This mechanism appears to be responsible for specifying NB5-3 identity to a row 5 neuroblast and preventing Wg from specifying NB4-2 identity to that cell...
  2. ncbi request reprint Upregulation of Mitimere and Nubbin acts through cyclin E to confer self-renewing asymmetric division potential to neural precursor cells
    Krishna Moorthi Bhat
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Development 131:1123-34. 2004
    ..These results add to our understanding of maintenance and loss of pluripotential stem cell identity...
  3. ncbi request reprint frizzled and frizzled 2 play a partially redundant role in wingless signaling and have similar requirements to wingless in neurogenesis
    K M Bhat
    Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Cell 95:1027-36. 1998
    ..Since the penetrance of the CNS phenotypes is not complete in double mutants, additional components that allow some degree of Wg signaling must exist in vivo...
  4. pmc The posterior determinant gene nanos is required for the maintenance of the adult germline stem cells during Drosophila oogenesis
    K M Bhat
    Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Genetics 151:1479-92. 1999
    ..In these mutant males, spermatogenesis is progressively affected and these males eventually become sterile. These results indicate novel requirements for nos in the Drosophila germline...
  5. ncbi request reprint Segment polarity genes in neuroblast formation and identity specification during Drosophila neurogenesis
    K M Bhat
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Bioessays 21:472-85. 1999
    ....
  6. ncbi request reprint Cell division genes promote asymmetric interaction between Numb and Notch in the Drosophila CNS
    P Wai
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Development 126:2759-70. 1999
    ..This suggests that microtubules are involved in mediating the antagonistic interaction between Nb and N during RP2 and sib fate specification...
  7. ncbi request reprint Slit signaling promotes the terminal asymmetric division of neural precursor cells in the Drosophila CNS
    B Mehta
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Development 128:3161-8. 2001
    ..These results tie a cell-non-autonomous signaling pathway to the asymmetric division of precursor cells during neurogenesis...
  8. ncbi request reprint Establishment of stem cell identity in the Drosophila germline
    K M Bhat
    Department of Molecular Biology, Princeton University, New Jersey, USA
    Dev Dyn 210:371-82. 1997
    ..When only a single pre-stem cell is sequestered by an ovariole, this cell does not assume stem cell identity, but instead follows the cystoblast-cystocyte differentiation pathway...
  9. ncbi request reprint Cell-cell signaling during neurogenesis: some answers and many questions
    K M Bhat
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Int J Dev Biol 42:127-39. 1998
    ..It discusses the contributions of the neurogenic genes Notch and Delta and the signaling pathways controlled by wingless, patched and hedgehog in neuroblast formation, neuroblast identity specification and neuroblast lineage elaboration...
  10. ncbi request reprint Generating asymmetry: with and without self-renewal
    Ivana Gaziova
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch School of Medicine, Galveston, Texas 77555, USA
    Prog Mol Subcell Biol 45:143-78. 2007
    ....
  11. pmc Regulation of axon guidance by slit and netrin signaling in the Drosophila ventral nerve cord
    Krishna Moorthi Bhat
    Department of Neuroscience and Cell Biology, School of Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA
    Genetics 176:2235-46. 2007
    ..Our results argue that double mutant epistasis is most definitive only if the penetrance of the phenotypes of the mutants involved is complete...
  12. ncbi request reprint Patched regulation of axon guidance is by specifying neural identity in the Drosophila nerve cord
    Tanuja T Merianda
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Dev Genes Evol 215:285-96. 2005
    ..These results provide insight into how mis-specification and loss of neurons can non-autonomously contribute to defects in axon pathfinding...
  13. pmc Slit-roundabout signaling neutralizes netrin-Frazzled-mediated attractant cue to specify the lateral positioning of longitudinal axon pathways
    Krishna Moorthi Bhat
    Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia 30322
    Genetics 170:149-59. 2005
    ..Thus, the growth cones of longitudinal tracts subjected to two opposing forces are able to block one with the other and specify their correct lateral positioning along the midline...
  14. pmc Differential effects of Drosophila mastermind on asymmetric cell fate specification and neuroblast formation
    Barry Yedvobnick
    Department of Biology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Genetics 166:1281-9. 2004
    ..Our results suggest that Mam proteins might associate during the asymmetric specification of cell fates and that the N-terminal region of the protein plays a role in this process...
  15. ncbi request reprint A positive role for patched-smoothened signaling in promoting cell proliferation during normal head development in Drosophila
    Baragur V Shyamala
    Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Development 129:1839-47. 2002
    ....
  16. pmc Wingless activity in the precursor cells specifies neuronal migratory behavior in the Drosophila nerve cord
    Krishna Moorthi Bhat
    Department of Neuroscience and Cell Biology, University of Texas Medical School, Galveston, TX 77555, USA
    Dev Biol 311:613-22. 2007
    ....