M Tohen

Summary

Affiliation: Eli Lilly and Company
Country: USA

Publications

  1. ncbi request reprint A meta-analysis of the use of typical antipsychotic agents in bipolar disorder
    M Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    J Affect Disord 65:85-93. 2001
  2. ncbi request reprint Efficacy of olanzapine in acute bipolar mania: a double-blind, placebo-controlled study. The Olanzipine HGGW Study Group
    M Tohen
    Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285 USA
    Arch Gen Psychiatry 57:841-9. 2000
  3. ncbi request reprint Olanzapine versus haloperidol in schizoaffective disorder, bipolar type
    M Tohen
    Lilly Research Laboratories, Indianapolis, IN, USA
    J Affect Disord 67:133-40. 2001
  4. ncbi request reprint Olanzapine versus haloperidol treatment in first-episode psychosis
    T M Sanger
    Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA
    Am J Psychiatry 156:79-87. 1999
  5. ncbi request reprint A double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients diagnosed with bipolar mania
    K Meehan
    Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285, USA
    J Clin Psychopharmacol 21:389-97. 2001
  6. ncbi request reprint Onset of action of antipsychotics in the treatment of mania
    M Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Bipolar Disord 2:261-8. 2000
  7. ncbi request reprint Medication prescribing patterns for patients with bipolar I disorder in hospital settings: adherence to published practice guidelines
    P Z Lim
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Bipolar Disord 3:165-73. 2001
  8. ncbi request reprint Olanzapine versus haloperidol in the treatment of acute mania: clinical outcomes, health-related quality of life and work status
    L Shi
    Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
    Int Clin Psychopharmacol 17:227-37. 2002
  9. ncbi request reprint The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. II. Baseline characteristics of the "prodromal" sample
    T J Miller
    Yale University, New Haven, CT, USA
    Schizophr Res 61:19-30. 2003
  10. ncbi request reprint The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. I. Study rationale and design
    T H McGlashan
    Department of Psychiatry, Yale University School of Medicine, 301 Cedar Street, New Haven, CT 06519, USA
    Schizophr Res 61:7-18. 2003

Collaborators

Detail Information

Publications16

  1. ncbi request reprint A meta-analysis of the use of typical antipsychotic agents in bipolar disorder
    M Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    J Affect Disord 65:85-93. 2001
    ..Despite these concerns and the availability of mood stabilizing agents, the treatment of bipolar disorder with typical antipsychotic agents appears to be widespread...
  2. ncbi request reprint Efficacy of olanzapine in acute bipolar mania: a double-blind, placebo-controlled study. The Olanzipine HGGW Study Group
    M Tohen
    Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285 USA
    Arch Gen Psychiatry 57:841-9. 2000
    ..We compared the efficacy and safety of olanzapine vs placebo for the treatment of acute bipolar mania...
  3. ncbi request reprint Olanzapine versus haloperidol in schizoaffective disorder, bipolar type
    M Tohen
    Lilly Research Laboratories, Indianapolis, IN, USA
    J Affect Disord 67:133-40. 2001
    ..The present analysis was performed on data from a subsample of patients with schizoaffective disorder, bipolar type, who participated in a multicenter, double-blind study comparing olanzapine to haloperidol...
  4. ncbi request reprint Olanzapine versus haloperidol treatment in first-episode psychosis
    T M Sanger
    Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA
    Am J Psychiatry 156:79-87. 1999
    ..Hence, the authors examined patients with first-episode psychosis to determine the efficacy and safety of olanzapine and haloperidol treatment...
  5. ncbi request reprint A double-blind, randomized comparison of the efficacy and safety of intramuscular injections of olanzapine, lorazepam, or placebo in treating acutely agitated patients diagnosed with bipolar mania
    K Meehan
    Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285, USA
    J Clin Psychopharmacol 21:389-97. 2001
    ..These findings suggest that intramuscular olanzapine is a safe and effective treatment for reducing acute agitation in patients with bipolar mania...
  6. ncbi request reprint Onset of action of antipsychotics in the treatment of mania
    M Tohen
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Bipolar Disord 2:261-8. 2000
    ..This article reviews the available published data from controlled, blinded studies regarding the latency of responses to antipsychotics in patients with acute mania...
  7. ncbi request reprint Medication prescribing patterns for patients with bipolar I disorder in hospital settings: adherence to published practice guidelines
    P Z Lim
    Lilly Research Laboratories, Indianapolis, IN 46285, USA
    Bipolar Disord 3:165-73. 2001
    ..CONCLUSIONS: Results suggest that a substantial proportion of patients with bipolar I disorder are discharged from hospitals on medications not generally recommended by current practice guidelines...
  8. ncbi request reprint Olanzapine versus haloperidol in the treatment of acute mania: clinical outcomes, health-related quality of life and work status
    L Shi
    Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
    Int Clin Psychopharmacol 17:227-37. 2002
    ..In conclusion, compared to haloperidol, olanzapine treatment was comparably effective in the remission of bipolar mania and significantly improved HRQOL and work status in patients with bipolar I disorder...
  9. ncbi request reprint The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. II. Baseline characteristics of the "prodromal" sample
    T J Miller
    Yale University, New Haven, CT, USA
    Schizophr Res 61:19-30. 2003
    ..Subsequent reports will detail the effects of drug versus placebo on prodromal symptoms, neuropsychological profile, and the rate of conversion to psychosis...
  10. ncbi request reprint The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. I. Study rationale and design
    T H McGlashan
    Department of Psychiatry, Yale University School of Medicine, 301 Cedar Street, New Haven, CT 06519, USA
    Schizophr Res 61:7-18. 2003
    ..The integration of these novel elements into an otherwise typical clinical trial design is detailed. The companion report will address sample recruitment and the clinical phenomenology at baseline of this putative "prodromal" entity...
  11. ncbi request reprint Functional impairment in patients with mania: baseline results of the EMBLEM study
    I Goetz
    European Health Outcomes, Lilly Research Centre, Windlesham, Surrey, UK
    Bipolar Disord 9:45-52. 2007
    ..We present an overview of the study design and patient characteristics at baseline while focusing on factors influencing work performance in the year prior to enrollment...
  12. ncbi request reprint Treatment of bipolar I rapid cycling patients during dysphoric mania with olanzapine
    Ana Gonzalez-Pinto
    Psychiatric Department, Santiago Apostol Hospital, Osakidetza Mental Health System, Vitoria, Spain
    J Clin Psychopharmacol 22:450-4. 2002
    ..96 kg in women, 2.20 +/- 2.28 kg in men). Our results suggest that olanzapine combined with mood stabilizers is safe and effective in the treatment of the manic and the depressive symptoms of dysphoric mania with a rapid cycling course...
  13. ncbi request reprint Patterns of drug treatment for manic episode in the clinical practice. Outcomes of the Spanish sample in the EMBLEM Study
    A Montoya
    Laboratorios Lilly, Spain
    Actas Esp Psiquiatr 35:315-22. 2007
    ..Although treatment for mania has been studied extensively in randomized clinical trials, there are few data that address how these patients are truly managed in clinical, functional, and economic terms in the psychiatric practice in Spain...
  14. ncbi request reprint Olanzapine as alternative therapy for patients with haloperidol-induced extrapyramidal symptoms: results of a multicenter, collaborative trial in Latin America
    J A Costa E Silva
    , Rio de Janeiro, Brazil
    J Clin Psychopharmacol 21:375-81. 2001
    ..7% of patients at endpoint. Results suggest that a direct switch to olanzapine is a therapeutic option when patients with haloperidol-induced EPS are unable to tolerate a more gradual switch...
  15. ncbi request reprint What makes a drug a primary mood stabilizer?
    P E Keck
    Biological Psychiatry Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Mol Psychiatry 7:S8-14. 2002
    ..In addition, potential pharmacological mechanisms underlying mood-stabilizing effects of established compounds are reviewed...
  16. ncbi request reprint Brief communication: pathological narcissism in bipolar disorder patients
    D Stormberg
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    J Pers Disord 12:179-85. 1998
    ..However, when manic, bipolar patients do appear similar to the narcissistic group, sharing 12 out of 14 of the identifying criteria for NPD. The results support the inclusion of mania in the differential diagnosis of NPD...