Stephen J Iturria
Affiliation: Eli Lilly and Company
- Genome-wide linkage analysis of systolic blood pressure: a comparison of two approaches to phenotype definitionSusan L Slager
Division of Biostatistics, Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
BMC Genet 4:S13. 2003..For each approach, multipoint linkage analysis was performed using the residuals and the SOLAR computer program. Our results show little difference between the methods based on the LOD scores...
- Statistical inference for relative potency in bivariate dose-response assays with correlated responsesStephen J Iturria
Eli Lilly and Company, Lilly Corporate Center, Global Statistical Sciences, Indianapolis, IN 46285, USA
J Biopharm Stat 15:343-51. 2005..Results from a simulation study suggest that a post hoc adjustment for the correlation in parameter estimates obtained from univariate fits provides nearly as much power to detect differences in potency as a bivariate response model fit...
- Identification of a global gene expression signature of B-chronic lymphocytic leukemiaDiane F Jelinek
Department of Immunology, Mayo Graduate and Medical Schools, Mayo Clinic, Rochester, MN 55905, USA
Mol Cancer Res 1:346-61. 2003..Finally, we identified a group of 31 genes that distinguish between low (Rai stage 0) and high (Rai stage 4) risk patients, suggesting that there may also be a gene expression signature that associates with disease progression...