R R Bowsher

Summary

Affiliation: Eli Lilly and Company
Country: USA

Publications

  1. ncbi request reprint Sensitive RIA for the specific determination of insulin lispro
    R R Bowsher
    Department of Drug Disposition, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
    Clin Chem 45:104-10. 1999
  2. ncbi request reprint An immunoadsorption strategy to produce specific antisera against analogs of human proteins: development of sensitive and specific radioimmunoassays for two analogs of human leptin
    P Brown-Augsburger
    Department of Drug Disposition, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285, USA
    J Pharm Biomed Anal 23:687-96. 2000
  3. ncbi request reprint Effects of circulating IGF-I on glucose and amino acid kinetics in the ovine fetus
    E A Liechty
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, USA
    Am J Physiol 271:E177-85. 1996
  4. ncbi request reprint A sensitive chemiluminescent enzyme immunoassay for the bioanalysis of carboxyl-terminal B-chain analogues of human insulin
    Y Cao
    Drug Disposition, Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46140, USA
    J Pharm Biomed Anal 26:53-61. 2001
  5. ncbi request reprint Urinary desmosine as a biomarker in acute lung injury
    J A Fill
    Eli Lilly and Co, Lilly Corporate Center, Indianapolis, IN 46285, USA
    Biomarkers 11:85-96. 2006

Collaborators

  • W H Lee
  • J A Fill
  • Y Cao
  • P Brown-Augsburger
  • E A Liechty
  • W C Smith
  • R L Gingerich
  • P Santa
  • M Masnyk
  • S C Denne
  • H Moorehead
  • D W Boyle

Detail Information

Publications5

  1. ncbi request reprint Sensitive RIA for the specific determination of insulin lispro
    R R Bowsher
    Department of Drug Disposition, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA
    Clin Chem 45:104-10. 1999
    ..The RIA has a low limit of quantification (17.2 pmol/L); has no interference from insulin, proinsulin, or C-peptide; and has interassay CVs of 2.6-13.4%. The new RIA is useful for measuring serum concentrations of insulin lispro...
  2. ncbi request reprint An immunoadsorption strategy to produce specific antisera against analogs of human proteins: development of sensitive and specific radioimmunoassays for two analogs of human leptin
    P Brown-Augsburger
    Department of Drug Disposition, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285, USA
    J Pharm Biomed Anal 23:687-96. 2000
    ..This technique has the potential for broad application in the development of assays capable of specifically measuring protein analogs without cross-reactivity to an endogenous substance...
  3. ncbi request reprint Effects of circulating IGF-I on glucose and amino acid kinetics in the ovine fetus
    E A Liechty
    Department of Pediatrics, Indiana University School of Medicine, Indianapolis, USA
    Am J Physiol 271:E177-85. 1996
    ..90 +/- 0.76 to 6.52 +/- 0.81 mumol/min, P = 0.025), more so in the fasted than the fed state. These results indicate a significant antiproteolytic endocrine effect for IGF-I in the late-gestation mammalian fetus...
  4. ncbi request reprint A sensitive chemiluminescent enzyme immunoassay for the bioanalysis of carboxyl-terminal B-chain analogues of human insulin
    Y Cao
    Drug Disposition, Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46140, USA
    J Pharm Biomed Anal 26:53-61. 2001
    ..The sensitive chemiluminescent detection method is simple to perform and should be readily adaptable for ELISAs of other therapeutic proteins...
  5. ncbi request reprint Urinary desmosine as a biomarker in acute lung injury
    J A Fill
    Eli Lilly and Co, Lilly Corporate Center, Indianapolis, IN 46285, USA
    Biomarkers 11:85-96. 2006
    ..Hydrolysis of urine samples appears necessary for optimal measurement of urine desmosine...