Scott E Loveless

Summary

Affiliation: DuPont Haskell Laboratory for Health and Environmental Sciences
Country: USA

Publications

  1. ncbi request reprint Inhalation toxicity of 1,3-propanediol in the rat
    Robert S Scott
    DuPont de Nemours and Company, Haskell Laboratory for Health and Environmental Sciences, Newark, Delaware 19714, USA
    Inhal Toxicol 17:487-93. 2005
  2. doi request reprint Interlaboratory study of the primary antibody response to sheep red blood cells in outbred rodents following exposure to cyclophosphamide or dexamethasone
    Scott E Loveless
    DuPont Haskell Laboratory for Health and Environmental Sciences, Newark, Delaware 19714, USA
    J Immunotoxicol 4:233-8. 2007
  3. doi request reprint Potency values from the local lymph node assay: application to classification, labelling and risk assessment
    S E Loveless
    DuPont Haskell Global Centers for Health and Environmental Sciences, Newark, DE, USA
    Regul Toxicol Pharmacol 56:54-66. 2010
  4. ncbi request reprint Comparative responses of rats and mice exposed to linear/branched, linear, or branched ammonium perfluorooctanoate (APFO)
    Scott E Loveless
    DuPont Haskell Laboratory for Health and Environmental Sciences, Newark, DE 19714, United States
    Toxicology 220:203-17. 2006
  5. doi request reprint Evaluation of the immune system in rats and mice administered linear ammonium perfluorooctanoate
    Scott E Loveless
    DuPont Haskell Globel Centers for Health and Environmental Sciences, Newark, Delaware 19714, USA
    Toxicol Sci 105:86-96. 2008
  6. doi request reprint Toxicological evaluation of sodium perfluorohexanoate
    Scott E Loveless
    DuPont Haskell Global Centers for Health and Environmental Sciences, Elkton Rd, Newark, DE 19714 0050, USA
    Toxicology 264:32-44. 2009
  7. ncbi request reprint Acute, subchronic, and mutagenicity studies with norbornene fluoroalcohol
    Michael P DeLorme
    E I duPont de Nemours and Company, Haskell Laboratory for Health and Environmental Sciences, Newark, Delaware 19714 0050, USA
    Drug Chem Toxicol 28:379-95. 2005
  8. ncbi request reprint Subchronic, reproductive, and developmental toxicity of a fluorotelomer-based urethane polymeric product
    Judith C Stadler
    DuPont Haskell Laboratory for Health and Environmental Sciences, Newark, Delaware 19714, USA
    Drug Chem Toxicol 31:317-37. 2008
  9. doi request reprint Toxicological evaluation of 6:2 fluorotelomer alcohol
    Tessa Serex
    DuPont Haskell Global Centers for Health and Environmental Sciences, Newark, DE, USA DuPont Crop Protection, Newark, DE, USA
    Toxicology 319:1-9. 2014
  10. doi request reprint Absorption, distribution, metabolism, and excretion of [1-¹⁴C]-perfluorohexanoate ([¹⁴C]-PFHx) in rats and mice
    Shawn A Gannon
    DuPont Haskell Global Centers for Health and Environmental Sciences, Elkton Rd, Newark, DE 19714 0050, USA
    Toxicology 283:55-62. 2011

Detail Information

Publications12

  1. ncbi request reprint Inhalation toxicity of 1,3-propanediol in the rat
    Robert S Scott
    DuPont de Nemours and Company, Haskell Laboratory for Health and Environmental Sciences, Newark, Delaware 19714, USA
    Inhal Toxicol 17:487-93. 2005
    ..1,3-Propanediol does not appear to pose a significant hazard via inhalation of either the vapor or a vapor/aerosol mixture...
  2. doi request reprint Interlaboratory study of the primary antibody response to sheep red blood cells in outbred rodents following exposure to cyclophosphamide or dexamethasone
    Scott E Loveless
    DuPont Haskell Laboratory for Health and Environmental Sciences, Newark, Delaware 19714, USA
    J Immunotoxicol 4:233-8. 2007
    ..Additional compounds will need to be evaluated before concluding that one method is superior or more sensitive to the other in detecting suppression of the antibody response...
  3. doi request reprint Potency values from the local lymph node assay: application to classification, labelling and risk assessment
    S E Loveless
    DuPont Haskell Global Centers for Health and Environmental Sciences, Newark, DE, USA
    Regul Toxicol Pharmacol 56:54-66. 2010
    ....
  4. ncbi request reprint Comparative responses of rats and mice exposed to linear/branched, linear, or branched ammonium perfluorooctanoate (APFO)
    Scott E Loveless
    DuPont Haskell Laboratory for Health and Environmental Sciences, Newark, DE 19714, United States
    Toxicology 220:203-17. 2006
    ..Based on these results, and for the endpoints evaluated in this study, the toxicological database developed primarily from testing linear/branched APFO is applicable to linear APFO...
  5. doi request reprint Evaluation of the immune system in rats and mice administered linear ammonium perfluorooctanoate
    Scott E Loveless
    DuPont Haskell Globel Centers for Health and Environmental Sciences, Newark, Delaware 19714, USA
    Toxicol Sci 105:86-96. 2008
    ..In summary, no immune-related changes occurred in rats, even at doses causing systemic toxicity. In mice, immune-related changes occurred only at doses causing significant and profound systemic toxicity and stress...
  6. doi request reprint Toxicological evaluation of sodium perfluorohexanoate
    Scott E Loveless
    DuPont Haskell Global Centers for Health and Environmental Sciences, Elkton Rd, Newark, DE 19714 0050, USA
    Toxicology 264:32-44. 2009
    ..Benchmark doses (BMDL10) for nasal lesions were 13 and 21 mg/(kg day) for male and female rats, respectively. The relevance of the nasal lesions to humans is not known...
  7. ncbi request reprint Acute, subchronic, and mutagenicity studies with norbornene fluoroalcohol
    Michael P DeLorme
    E I duPont de Nemours and Company, Haskell Laboratory for Health and Environmental Sciences, Newark, Delaware 19714 0050, USA
    Drug Chem Toxicol 28:379-95. 2005
    ..Based on the above findings, NBFOH demonstrates the potential to produce allergic contact dermatitis, and subchronic inhalation studies indicate a no-observed-adverse-effect-level (NOAEL) of 410 mg/m(3)...
  8. ncbi request reprint Subchronic, reproductive, and developmental toxicity of a fluorotelomer-based urethane polymeric product
    Judith C Stadler
    DuPont Haskell Laboratory for Health and Environmental Sciences, Newark, Delaware 19714, USA
    Drug Chem Toxicol 31:317-37. 2008
    ..Fetal weight was minimally decreased at 1000 mg/kg/day in the presence of slight maternal toxicity; the NOAEL for developmental parameters was 250 mg/kg/day. The polymeric product was not a specific developmental or reproductive toxin...
  9. doi request reprint Toxicological evaluation of 6:2 fluorotelomer alcohol
    Tessa Serex
    DuPont Haskell Global Centers for Health and Environmental Sciences, Newark, DE, USA DuPont Crop Protection, Newark, DE, USA
    Toxicology 319:1-9. 2014
    ..For risk assessment purposes, the recommended point of departure is the more conservative study NOAEL of 5mg/kg/day...
  10. doi request reprint Absorption, distribution, metabolism, and excretion of [1-¹⁴C]-perfluorohexanoate ([¹⁴C]-PFHx) in rats and mice
    Shawn A Gannon
    DuPont Haskell Global Centers for Health and Environmental Sciences, Elkton Rd, Newark, DE 19714 0050, USA
    Toxicology 283:55-62. 2011
    ..25, 1, and 24 h) after dosing to investigate the tissue clearance kinetics of PFHx following a single dose at 2 or 100 mg/kg. In all tissues except skin, PFHx was not quantifiable 24 h after dosing in both sexes of the two species...
  11. doi request reprint Toxicological assessment of tridecafluorohexylethyl methacrylate (6:2 FTMAC)
    Sathanandam S Anand
    DuPont Haskell Global Centers for Health and Environmental Sciences, Newark, DE 19714, USA
    Toxicology 292:42-52. 2012
    ..6 mg/L, while the 48-h EC50 in Daphnia magna, based on nominal concentrations, was >120 mg/L. Overall, 6:2 FTMAC is considered to have low toxicity potential based on these studies...
  12. ncbi request reprint Commentary on hormetic dose-response relationships in immunology: occurrence, quantitative features of the dose response, mechanistic foundations, and clinical implications
    Gregory S Ladics
    DuPont Haskell Laboratory for Health and Environmental Sciences, Newark, Delaware 19714, USA
    Crit Rev Toxicol 35:303-4. 2005