Christopher W Woods

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Use of sentinel laboratories by clinicians to evaluate potential bioterrorism and emerging infections
    Brian C Pien
    Division of Infectious Diseases and Clinical Microbiology Laboratory, Duke University Medical Center, Durham, NC, USA
    Clin Infect Dis 42:1311-24. 2006
  2. ncbi request reprint Early surgery in patients with infective endocarditis: a propensity score analysis
    Olcay Aksoy
    Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC, USA
    Clin Infect Dis 44:364-72. 2007
  3. pmc Heterogeneous vancomycin-intermediate susceptibility phenotype in bloodstream methicillin-resistant Staphylococcus aureus isolates from an international cohort of patients with infective endocarditis: prevalence, genotype, and clinical significance
    In Gyu Bae
    Duke Clinical Research Institute, Durham, North Carolina, USA
    J Infect Dis 200:1355-66. 2009
  4. pmc Bartonella vinsonii subsp. berkhoffii and Bartonella henselae bacteremia in a father and daughter with neurological disease
    Edward B Breitschwerdt
    Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough St, Raleigh, NC, USA
    Parasit Vectors 3:29. 2010
  5. pmc Bayesian inference of the number of factors in gene-expression analysis: application to human virus challenge studies
    Bo Chen
    Electrical and Computer Engineering Department, Duke University, Durham, NC, USA
    BMC Bioinformatics 11:552. 2010
  6. ncbi request reprint Virulence associated with outbreak-related strains of Burkholderia cepacia complex among a cohort of patients with bacteremia
    Christopher W Woods
    Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Clin Infect Dis 38:1243-50. 2004
  7. ncbi request reprint Endocarditis caused by Staphylococcus aureus with reduced susceptibility to vancomycin
    Christopher W Woods
    Clinical Microbiology, Durham Veterans Administration Medical Center, Durham, NC 27705, USA
    Clin Infect Dis 38:1188-91. 2004
  8. ncbi request reprint Risk factors for human anthrax among contacts of anthrax-infected livestock in Kazakhstan
    Christopher W Woods
    Division of Infectious Diseases, Duke University Medical Center, 508 Fulton Street, Durham, NC 27705, USA
    Am J Trop Med Hyg 71:48-52. 2004
  9. ncbi request reprint Emergence of Salmonella enterica serotype Paratyphi A as a major cause of enteric fever in Kathmandu, Nepal
    Christopher W Woods
    Duke University Medical Center, Durham, NC, USA
    Trans R Soc Trop Med Hyg 100:1063-7. 2006
  10. pmc An outbreak of Rift Valley fever in Northeastern Kenya, 1997-98
    Christopher W Woods
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Emerg Infect Dis 8:138-44. 2002

Detail Information

Publications76

  1. ncbi request reprint Use of sentinel laboratories by clinicians to evaluate potential bioterrorism and emerging infections
    Brian C Pien
    Division of Infectious Diseases and Clinical Microbiology Laboratory, Duke University Medical Center, Durham, NC, USA
    Clin Infect Dis 42:1311-24. 2006
    ....
  2. ncbi request reprint Early surgery in patients with infective endocarditis: a propensity score analysis
    Olcay Aksoy
    Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, NC, USA
    Clin Infect Dis 44:364-72. 2007
    ..Largely because of these limitations, the role of surgery in long-term survival has not been adequately studied...
  3. pmc Heterogeneous vancomycin-intermediate susceptibility phenotype in bloodstream methicillin-resistant Staphylococcus aureus isolates from an international cohort of patients with infective endocarditis: prevalence, genotype, and clinical significance
    In Gyu Bae
    Duke Clinical Research Institute, Durham, North Carolina, USA
    J Infect Dis 200:1355-66. 2009
    ..Using a multinational collection of isolates from methicillin-resistant S. aureus (MRSA) infective endocarditis (IE), we characterized patients with IE with and without hVISA, and we genotyped the infecting strains...
  4. pmc Bartonella vinsonii subsp. berkhoffii and Bartonella henselae bacteremia in a father and daughter with neurological disease
    Edward B Breitschwerdt
    Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, 4700 Hillsborough St, Raleigh, NC, USA
    Parasit Vectors 3:29. 2010
    ..Vector transmission is suspected among dogs and wild canines, which are the primary reservoir hosts. This investigation was initiated to determine if pets and family members were infected with one or more Bartonella species...
  5. pmc Bayesian inference of the number of factors in gene-expression analysis: application to human virus challenge studies
    Bo Chen
    Electrical and Computer Engineering Department, Duke University, Durham, NC, USA
    BMC Bioinformatics 11:552. 2010
    ..The posterior density function on the model parameters is computed using Gibbs sampling and variational Bayesian (VB) analysis...
  6. ncbi request reprint Virulence associated with outbreak-related strains of Burkholderia cepacia complex among a cohort of patients with bacteremia
    Christopher W Woods
    Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Clin Infect Dis 38:1243-50. 2004
    ..5; 95% confidence interval, 1.20-25.02). B. cenocepacia is an emerging nosocomial pathogen. Certain strains are associated with an enhanced capacity for interpatient spread and poor outcome...
  7. ncbi request reprint Endocarditis caused by Staphylococcus aureus with reduced susceptibility to vancomycin
    Christopher W Woods
    Clinical Microbiology, Durham Veterans Administration Medical Center, Durham, NC 27705, USA
    Clin Infect Dis 38:1188-91. 2004
    ..We report the strain characterization and treatment of a patient with SARV IE...
  8. ncbi request reprint Risk factors for human anthrax among contacts of anthrax-infected livestock in Kazakhstan
    Christopher W Woods
    Division of Infectious Diseases, Duke University Medical Center, 508 Fulton Street, Durham, NC 27705, USA
    Am J Trop Med Hyg 71:48-52. 2004
    ..9-9.6). Contact with infected livestock, in particular butchering, is associated with developing anthrax. The risk may be exacerbated by the presence of cuts on the hands at the time of contact with the animal or animal products...
  9. ncbi request reprint Emergence of Salmonella enterica serotype Paratyphi A as a major cause of enteric fever in Kathmandu, Nepal
    Christopher W Woods
    Duke University Medical Center, Durham, NC, USA
    Trans R Soc Trop Med Hyg 100:1063-7. 2006
    ..In contrast, only 21 (36%) of the 58 S. Typhi isolates exhibited a common genotype, which is consistent with endemic disease from multiple sources...
  10. pmc An outbreak of Rift Valley fever in Northeastern Kenya, 1997-98
    Christopher W Woods
    Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Emerg Infect Dis 8:138-44. 2002
    ..Public education during epizootics may reduce human illness and deaths associated with future outbreaks...
  11. pmc Disease progression in hemodynamically stable patients presenting to the emergency department with sepsis
    Seth W Glickman
    Department of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA
    Acad Emerg Med 17:383-90. 2010
    ..To enhance the ability to intervene in patients with lesser illness severity, a better understanding of the natural history of the early progression from simple infection to more severe illness is needed...
  12. doi request reprint The clinical and prognostic importance of positive blood cultures in adults
    Brian C Pien
    Duke University Medical Center, Durham, NC, USA
    Am J Med 123:819-28. 2010
    ....
  13. pmc Discriminative value of inflammatory biomarkers for suspected sepsis
    Ephraim L Tsalik
    Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA
    J Emerg Med 43:97-106. 2012
    ..Circulating biomarkers can facilitate sepsis diagnosis, enabling early management and improved outcomes. Procalcitonin (PCT) has been suggested to have superior diagnostic utility compared to other biomarkers...
  14. pmc Controlled clinical comparison of plastic and glass bottles of BacT/ALERT FA medium for culturing organisms from blood of adult patients
    Cathy A Petti
    Clinical Microbiology Laboratory, Duke University Medical Center, Durham, North Carolina, USA
    J Clin Microbiol 43:1960-2. 2005
    ..We conclude that the BacT/ALERT plastic and glass FA bottles are comparable for recovery of microorganisms and that the safety advantage of plastic bottles can be achieved without compromising performance...
  15. pmc Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA
    Preeta K Kutty
    Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 16:197-204. 2010
    ..1, 95% CI 2.9-28.9), to have gastroesophageal reflux disease (aOR 11.2, 95% CI 1.9-64.2), and to have cardiac failure (aOR 3.8, 95% CI 1.1-13.7). Risk factors for CA-CDI overlap with those for healthcare-associated infection...
  16. pmc Methicillin-susceptible Staphylococcus aureus endocarditis isolates are associated with clonal complex 30 genotype and a distinct repertoire of enterotoxins and adhesins
    Juhsien J C Nienaber
    Duke University Medical Center Division of Infectious Diseases and International Health, Durham, North Carolina, USA
    J Infect Dis 204:704-13. 2011
    ..aureus in clonal complex (CC) 30 is associated with hematogenous complications and (2) test the hypothesis that specific genetic characteristics in S. aureus are associated with infection severity...
  17. ncbi request reprint Risk factors for Burkholderia cepacia complex bacteremia among intensive care unit patients without cystic fibrosis: a case-control study
    Adam M Bressler
    Infectious Disease Specialists of Atlanta and Clinical Microbiology Laboratory, DeKalb Medical Center, Atlanta, GA, USA
    Infect Control Hosp Epidemiol 28:951-8. 2007
    ..The Burkholderia cepacia complex is associated with colonization or disease in patients with cystic fibrosis (CF). For patients without CF, this complex is poorly understood apart from its presence in occasional point source outbreaks...
  18. pmc Genotypic diversity of coagulase-negative staphylococci causing endocarditis: a global perspective
    Cathy A Petti
    Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah 84108, USA
    J Clin Microbiol 46:1780-4. 2008
    ..In particular, rpoB sequence data demonstrated unique genetic signatures with the potential to serve as an important tool for global surveillance...
  19. ncbi request reprint Clinical identifiers of complicated Staphylococcus aureus bacteremia
    Vance G Fowler
    Division of Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA
    Arch Intern Med 163:2066-72. 2003
    ..This investigation sought to define readily available clinical characteristics that could help identify patients at risk for complicated SAB...
  20. pmc Controlled clinical comparison of BacT/ALERT standard aerobic and standard anaerobic blood culture bottles inoculated directly or after transport in sodium polyanethol sulfonate tubes
    Brian C Pien
    Durham VA Medical Center, Section 113, 508 Fulton St, Durham, NC 27705, USA
    J Clin Microbiol 45:1357-9. 2007
    ..No significant differences in yields or times to detection were found for 387 clinically important isolates from 4,306 blood culture sets...
  21. doi request reprint An Infection Control Program for a 2009 influenza A H1N1 outbreak in a university-based summer camp
    Ephraim L Tsalik
    Department of Medicine, Duke University Medical Center, Durham, North Carolinam, USA
    J Am Coll Health 59:419-26. 2011
    ..Describe two 2009-H1N1 influenza outbreaks in university-based summer camps and the implementation of an infection control program...
  22. pmc Controlled clinical comparison of plastic versus glass bottles of BacT/ALERT PF medium for culturing blood from children
    Cathy A Petti
    Clinical Microbiology Laboratory, Duke University School of Medicine, Durham, North Carolina, USA
    J Clin Microbiol 43:445-7. 2005
    ..We found that the PPF and PF bottles were comparable for recovery of microorganisms and that the safety advantage of plastic bottles can be achieved without compromising performance...
  23. pmc A host-based RT-PCR gene expression signature to identify acute respiratory viral infection
    Aimee K Zaas
    Institute for Genome Sciences and Policy, Duke University School of Medicine, Durham, NC 27710, USA
    Sci Transl Med 5:203ra126. 2013
    ....
  24. doi request reprint A case-control study of community-associated Clostridium difficile infection: no role for proton pump inhibitors
    Susanna Naggie
    Division of Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA
    Am J Med 124:276.e1-7. 2011
    ..The epidemiology of community-associated Clostridium difficile infection is not well known. We performed a multicenter, case-control study to further describe community-associated C. difficile infection and assess novel risk factors...
  25. doi request reprint Respiratory syncytial virus outbreak in a long-term care facility detected using reverse transcriptase polymerase chain reaction: an argument for real-time detection methods
    L Brett Caram
    Division of Infectious Diseases, Duke University Medical Center, and Infectious Diseases Section, Durham Veterans Affairs Medical Center, Durham, NC 27705, USA
    J Am Geriatr Soc 57:482-5. 2009
    ..To report an outbreak of respiratory synctyial virus (RSV) in a long-term care facility (LTCF) during ongoing routine respiratory illness surveillance...
  26. doi request reprint Emergence of coagulase-negative staphylococci as a cause of native valve endocarditis
    Vivian H Chu
    Duke University Medical Center, Durham, North Carolina 27710, USA
    Clin Infect Dis 46:232-42. 2008
    ..Coagulase-negative staphylococci (CoNS) are an infrequent cause of native valve endocarditis (NVE), and our understanding of NVE caused by CoNS is incomplete...
  27. pmc A Genomic Signature of Influenza Infection Shows Potential for Presymptomatic Detection, Guiding Early Therapy, and Monitoring Clinical Responses
    Micah T McClain
    Center for Applied Genomics and Precision Medicine, Duke University Durham Veterans Affairs Medical Center Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina
    Open Forum Infect Dis 3:ofw007. 2016
    ....
  28. pmc Plasma microRNA signature as a noninvasive biomarker for acute graft-versus-host disease
    Bin Xiao
    Department of Immunology, Duke University Medical Center, Durham, NC
    Blood 122:3365-75. 2013
    ..Our results have identified a specific plasma miRNA signature that may serve as an independent biomarker for the prediction, diagnosis, and prognosis of aGVHD. ..
  29. doi request reprint Longitudinal analysis of leukocyte differentials in peripheral blood of patients with acute respiratory viral infections
    Micah T McClain
    Durham VA Medical Center, Durham, NC, United States Division of Infectious Diseases, Duke University Medical Center, Durham, NC, United States Electronic address
    J Clin Virol 58:689-95. 2013
    ..However, most published work is limited to a single timepoint at initial presentation to a medical provider, which may correspond to widely varying points in the course of disease...
  30. pmc A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2
    Christopher W Woods
    Institute for Genome Sciences and Policy, Duke University Medical Center, Durham, North Carolina, USA
    PLoS ONE 8:e52198. 2013
    ..The host genomic response to Influenza infection is robust and may provide the means for detection before typical clinical symptoms are apparent...
  31. pmc Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans
    Sun Hee Ahn
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University, Durham, North Carolina, USA
    PLoS ONE 8:e48979. 2013
    ..Furthermore, this study advances our understanding of S. aureus infection; the host response to it; and identifies new diagnostic and therapeutic avenues...
  32. doi request reprint Assessment of Clostridium difficile-associated disease surveillance definitions, North Carolina, 2005
    Preeta K Kutty
    Division of Healthcare Quality Promotion, National Center for Preparedness, Detection, and Control of Infectious Diseases, Centers for Disease Control and Prevention, Department of Health and Human Services, Atlanta, Georgia 30333, USA
    Infect Control Hosp Epidemiol 29:197-202. 2008
    ....
  33. pmc Associations between the genotypes of Staphylococcus aureus bloodstream isolates and clinical characteristics and outcomes of bacteremic patients
    Tahaniyat Lalani
    Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Clin Microbiol 46:2890-6. 2008
    ..In this study of bloodstream isolates collected as part of a multinational randomized clinical trial, USA 300 and pvl-constitutive MRSA strains were associated with better clinical outcomes...
  34. ncbi request reprint Risk factors for hematogenous complications of intravascular catheter-associated Staphylococcus aureus bacteremia
    Vance G Fowler
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Clin Infect Dis 40:695-703. 2005
    ..The role of both host and pathogen characteristics in hematogenous seeding following Staphylococcus aureus bacteremia is incompletely understood...
  35. ncbi request reprint Repeat infective endocarditis: differentiating relapse from reinfection
    Vivian H Chu
    Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
    Clin Infect Dis 41:406-9. 2005
    ..The agreement between clinical and molecular criteria was imperfect (agreement in 10 [77%] of 13 cases)...
  36. pmc Transcriptomic Analysis of the Host Response and Innate Resilience to Enterotoxigenic Escherichia coli Infection in Humans
    William E Yang
    Duke University School of Medicine, Department of Medicine, Duke University Center for Applied Genomics and Precision Medicine, Department of Medicine, Duke University
    J Infect Dis 213:1495-504. 2016
    ..Little is known about the host transcriptional response to infection. We report the first gene expression analysis of the human host response to experimental challenge with ETEC...
  37. doi request reprint Coagulase-negative staphylococcal prosthetic valve endocarditis--a contemporary update based on the International Collaboration on Endocarditis: prospective cohort study
    V H Chu
    Duke University Medical Center, Durham, NC 27710, USA
    Heart 95:570-6. 2009
    ..To describe the contemporary features of coagulase-negative staphylococcal (CoNS) prosthetic valve endocarditis (PVE)...
  38. doi request reprint Adherence to self-quarantine recommendations during an outbreak of norovirus infection
    Supriya Rao
    Duke University Medical Center, Durham, North Carolina, USA
    Infect Control Hosp Epidemiol 30:896-9. 2009
    ..Staff adherence was similar regardless of job responsibility. Incomplete adherence to recommendations could potentially accelerate and prolong infectious disease outbreaks...
  39. doi request reprint Antibacterial susceptibility testing in the clinical laboratory
    Thomas L Holland
    Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA
    Infect Dis Clin North Am 23:757-90, vii. 2009
    ..This updated version provides an overview of the important susceptibility concerns for most commonly isolated bacterial pathogens...
  40. pmc Host gene expression classifiers diagnose acute respiratory illness etiology
    Ephraim L Tsalik
    Center for Applied Genomics and Precision Medicine, Department of Medicine, Duke University, Durham, NC 27708, USA Emergency Medicine Service, Durham Veteran s Affairs Medical Center, Durham, NC 27705, USA Division of Infectious Diseases and International Health, Department of Medicine, Duke University, Durham, NC 27710, USA
    Sci Transl Med 8:322ra11. 2016
    ..These findings create an opportunity to develop and use host gene expression classifiers as diagnostic platforms to combat inappropriate antibiotic use and emerging antibiotic resistance. ..
  41. doi request reprint The current epidemiology and clinical decisions surrounding acute respiratory infections
    Aimee K Zaas
    Center for Applied Genomics and Precision Medicine, Duke University School of Medicine, Durham, NC, USA Department of Medicine, Duke University School of Medicine, Durham, NC, USA Electronic address
    Trends Mol Med 20:579-88. 2014
    ..Thus, an accurate test for the presence or absence of viral or bacterial infection is needed. In this review, we focus on recent research showing that the host-response (genomic, proteomic, or miRNA) can accomplish this task. ..
  42. doi request reprint DNA bioassay-on-chip using SERS detection for dengue diagnosis
    Hoan T Ngo
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    Analyst 139:5655-9. 2014
    ..Using the technique, specific oligonucleotide sequences of the dengue virus 4 were detected. ..
  43. pmc Streptococcus pneumoniae antigen test using positive blood culture bottles as an alternative method to diagnose pneumococcal bacteremia
    Cathy A Petti
    Clinical Microbiology Laboratory, Duke University Medical Center, Department of Pathology, Duke University School of Medicine, Durham, North Carolina, USA
    J Clin Microbiol 43:2510-2. 2005
    ..Use of the S. pneumoniae antigen test is an alternative method for identifying S. pneumoniae from positive blood culture bottles and may enable a diagnosis of pneumococcal bacteremia despite negative subcultures...
  44. pmc Phase II, randomized, multicenter, double-blind, placebo-controlled trial of a polyclonal anti-Staphylococcus aureus capsular polysaccharide immune globulin in treatment of Staphylococcus aureus bacteremia
    Mark E Rupp
    Division of Infectious Diseases, University of Nebraska Medical Center, 984031 Nebraska Medical Center, Omaha, NE 68198 4031, USA
    Antimicrob Agents Chemother 51:4249-54. 2007
    ..gov number NCT00063089)...
  45. ncbi request reprint Leptotrichia endocarditis: report of two cases from the International Collaboration on Endocarditis (ICE) database and review of previous cases
    L B Caram
    Division of Infectious Diseases, Duke University Medical Center, Box 3824, Durham, NC 27710, USA
    Eur J Clin Microbiol Infect Dis 27:139-43. 2008
    ..goodfellowii sp. nov. Both cases were identified using 16S rRNA gene sequencing. Review of the English literature revealed only two other cases of Leptotrichia sp. endocarditis...
  46. pmc Gene Expression Profiles Link Respiratory Viral Infection, Platelet Response to Aspirin, and Acute Myocardial Infarction
    Jason J Rose
    Center for Applied Genomics and Precision Medicine, Duke University Medical Center, Durham, North Carolina, United States of America Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 10:e0132259. 2015
    ....
  47. doi request reprint What was old is new again: using the host response to diagnose infectious disease
    Emily R Ko
    a 1 Department of Medicine Center for Applied Genomics and Precision Medicine, Duke University, Durham, NC 27708, USA
    Expert Rev Mol Diagn 15:1143-58. 2015
    ..The road ahead is promising, but obstacles remain before the impact of such advanced diagnostic modalities is felt at the bedside. ..
  48. pmc Surface-enhanced Raman scattering molecular sentinel nanoprobes for viral infection diagnostics
    Hsin Neng Wang
    Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA
    Anal Chim Acta 786:153-8. 2013
    ....
  49. pmc Automated detection of influenza-like illness using clinical surveillance markers at a Department of Veterans Affairs Medical Center
    Lawrence P Park
    Department of Medicine, Duke University School of Medicine, Durham, NC, USA
    Emerg Health Threats J 4:7108. 2011
    ..Using demographic and clinical measures from emergency department evaluations, we developed an automated surveillance system for influenza-like illness (ILI)...
  50. pmc Evaluation of four commercially available rapid serologic tests for diagnosis of leptospirosis
    Mary D Bajani
    Meningitis and Special Pathogens Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Clin Microbiol 41:803-9. 2003
    ..The ease of use and significantly high sensitivity and specificity of DST and ELISA make these good choices for diagnostic testing...
  51. pmc Controlled clinical comparison of BacT/ALERT standard aerobic medium with BACTEC standard aerobic medium for culturing blood
    Stanley Mirrett
    Clinical Microbiology Laboratory, Duke University Medical Center, Departments of Pathology, Duke University School of Medicine, Durham, North Carolina 27710, USA
    J Clin Microbiol 41:2391-4. 2003
    ..One BM bottle and seven BD bottles yielded false-negative results. We conclude that the BM medium provides improved recovery of microorganisms, especially staphylococci and yeasts, compared with that provided by the BD medium...
  52. ncbi request reprint Changing patient characteristics and the effect on mortality in endocarditis
    Christopher H Cabell
    Department of Medicine, Duke University Medical Center, Box 31020, Durham, NC 27710
    Arch Intern Med 162:90-4. 2002
    ..Limited data exist on recent demographic and microbiological changes in infective endocarditis (IE) and the impact of these changes on patient survival...
  53. pmc Multiplex PCR to diagnose bloodstream infections in patients admitted from the emergency department with sepsis
    Ephraim L Tsalik
    Department of Medicine, Division of Infectious Diseases, Duke University School of Medicine, Durham, North Carolina, USA
    J Clin Microbiol 48:26-33. 2010
    ..Real-time multiplex PCR has the potential to serve as an adjunct to conventional blood culture, adding diagnostic yield and shortening the time to pathogen identification...
  54. ncbi request reprint Increased case-fatality rate associated with outbreaks of Neisseria meningitidis infection, compared with sporadic meningococcal disease, in the United States, 1994-2002
    Richard Brooks
    Duke University School of Medicine, Durham, North Carolina, USA
    Clin Infect Dis 43:49-54. 2006
    ..Outbreaks of meningococcal disease are infrequent but important public health events. We characterize outbreak-associated cases in the United States and compare them with sporadic disease...
  55. doi request reprint Clinical presentation and response to treatment of novel influenza A H1N1 in a university-based summer camp population
    Ephraim L Tsalik
    Duke University Medical Center, Department of Internal Medicine, Durham, NC 27710, USA
    J Clin Virol 47:286-8. 2010
    ..Little is known about the clinical presentation and course of novel H1N1 influenza in summer camps...
  56. pmc Host-based Peripheral Blood Gene Expression Analysis for the Diagnosis of Infectious Diseases
    Zachary E Holcomb
    Duke University School of Medicine, Duke University, Durham, NC 27710, USA
    J Clin Microbiol . 2016
    ..Alterations in peripheral blood gene expression in the infected state are robust and reproducible, yielding diagnostic and prognostic information to help facilitate patient treatment decisions...
  57. pmc Extended-spectrum ß-Lactamase-producing Enterobacteriaceae as a Common Cause of Urinary Tract Infections in Sri Lanka
    L Gayani Tillekeratne
    Duke Global Health Institute, Durham, NC, USA
    Infect Chemother 48:160-165. 2016
    ..However, in Sri Lanka, the clinical and molecular epidemiology of ESBL-PE implicated in UTIs has not been well described...
  58. pmc Clinical MRSA isolates from skin and soft tissue infections show increased in vitro production of phenol soluble modulins
    Nicholas R Berlon
    Duke U Med Center, NC, USA
    J Infect 71:447-57. 2015
    ..This study tested the hypothesis that in vitro PSM production levels are associated with specific clinical phenotypes...
  59. pmc Renal systems biology of patients with systemic inflammatory response syndrome
    Ephraim L Tsalik
    Emergency Medicine Service, Durham Veterans Affairs Medical Center, Durham, North Carolina, USA
    Kidney Int 88:804-14. 2015
    ..These studies allude to several novel mechanisms whereby renal dysfunction contributes to critical illness...
  60. pmc Detection of Bartonella species in the blood of veterinarians and veterinary technicians: a newly recognized occupational hazard?
    Paul M Lantos
    1 Departments of Internal medicine and Pediatrics, Duke University School of Medicine, Durham, North Carolina
    Vector Borne Zoonotic Dis 14:563-70. 2014
    ..We have developed a detection method combining enrichment culture and molecular amplification, which increases testing sensitivity...
  61. pmc Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis
    Qin Yan
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, United States of America
    PLoS Pathog 10:e1004149. 2014
    ..These findings suggest that Dusp3 and Psme3 contribute to S. aureus infection susceptibility in A/J mice and play a role in human S. aureus infection. ..
  62. ncbi request reprint Non-O1 Vibrio cholerae septicemia: case report, discussion of literature, and relevance to bioterrorism
    Albert M L Anderson
    Department of Medicine, Durham Veterans Affairs Medical Center, Durham, NC, USA
    Diagn Microbiol Infect Dis 49:295-7. 2004
    ..NOVC takes on new significance given that it can be confused with toxigenic V. cholerae, a Centers for Disease Control and Prevention category B bioterrorism agent...
  63. ncbi request reprint Outbreak of leptospirosis among triathlon participants and community residents in Springfield, Illinois, 1998
    Juliette Morgan
    Meningitis and Special Pathogens Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA
    Clin Infect Dis 34:1593-9. 2002
    ..Health care providers and occupational and recreational users of bodies of freshwater in the United States should be aware of the risk of contracting leptospirosis, particularly after heavy rains...
  64. ncbi request reprint West Nile virus among hospitalized, febrile patients: a case for expanding diagnostic testing
    Ellen A Spotts Whitney
    Center for Public Health Preparedness and Research, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
    Vector Borne Zoonotic Dis 6:42-9. 2006
    ..When indicators of WNV activity are present and patients are likely to have had intensive mosquito exposure, WNV should be considered in the differential diagnosis of seriously ill, febrile patients...
  65. pmc Surveillance for unexplained deaths and critical illnesses due to possibly infectious causes, United States, 1995-1998
    Rana A Hajjeh
    Division of Bacterial and Mycotic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    Emerg Infect Dis 8:145-53. 2002
    ..The UNEX network model would improve U.S. diagnostic capacities and preparedness for emerging infections...
  66. pmc Widespread dissemination of CTX-M-15 genotype extended-spectrum-β-lactamase-producing enterobacteriaceae among patients presenting to community hospitals in the southeastern United States
    Luke F Chen
    Duke University Medical Center, Durham, North Carolina, USA
    Antimicrob Agents Chemother 58:1200-2. 2014
    ..coli, accounting for 48% of CTX-M-15-producing and 66% of CTX-M-14-producing isolates. In conclusion, the CTX-M genotype and ST131 E. coli were common among ESBL isolates from U.S. community hospitals. ..
  67. doi request reprint A novel diagnostic approach may reduce inappropriate antibiotic use for acute respiratory infections
    Lori L Hudson
    Department of Medicine, Duke University School of Medicine, Duke University, Durham, NC 27710, USA
    Expert Rev Anti Infect Ther 12:279-82. 2014
    ....
  68. doi request reprint Changes in childhood pneumonia and infant mortality rates following introduction of the 13-valent pneumococcal conjugate vaccine in Nicaragua
    Sylvia Becker-Dreps
    From the Department of Family Medicine, University of North Carolina School of Medicine, Chapel Hill, NC Department of Microbiology, National Autonomous University of Nicaragua, Leon, Nicaragua Department of Biostatistics, UNC Gillings School of Global Public Health, Chapel Hill, NC Sistemas Locales de Atención Integral a la Salud, León SILAIS León Hospital Epidemiology, Department of Pediatrics, Hospital Escuela Oscar Danilo Rosales Argüello HEODRA, Leon, Nicaragua Division of Infectious Diseases, Duke University School of Medicine, Durham, NC and Division of Infectious Diseases, University of North Carolina School of Medicine, Chapel Hill, NC
    Pediatr Infect Dis J 33:637-42. 2014
    ..We assessed changes in incidence rates of health facility visits for childhood pneumonia and infant mortality after PCV-13 introduction in the Department of León, Nicaragua...
  69. pmc H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination
    M Anthony Moody
    Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America
    PLoS ONE 6:e25797. 2011
    ..In contrast, a history of recent seasonal trivalent vaccine in younger adults was not associated with protection...
  70. doi request reprint Hemophagocytic lymphohistiocytosis in the premature neonate
    Christopher W Woods
    Duke University School of Nursing, Durham, North Carolina, USA
    Adv Neonatal Care 9:265-73. 2009
    ..Several case studies of premature neonates with HLH have recently been published. Therapeutic guidelines for HLH exist and, when identified, HLH in the premature infant can be successfully treated resulting in resolution of symptoms...
  71. ncbi request reprint Antibacterial susceptibility testing in the clinical laboratory
    Maria Joyce
    Division of Infectious Diseases, Duke University Medical Center, Durham, NC 27710, USA
    Infect Dis Clin North Am 18:401-34, vii. 2004
    ..The emergence of resistance in nearly all commonly isolated bacterial organisms has highlighted the need for ongoing dialogue between the laboratory and those who use its services...
  72. ncbi request reprint The impact of the Tsunami on hospitalizations at the tertiary care hospital in the Southern Province of Sri Lanka
    Truls Ostbye
    Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina, USA
    Am J Disaster Med 3:147-55. 2008
    ..To assist in preparing for future disasters, the authors sought to characterize the pattern of hospitalizations from the main impact zone in the Southern Province...
  73. pmc Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans
    Aimee K Zaas
    Division of Infectious Diseases and International Health, Department of Medicine, Duke University School of Medicine, Duke University, Durham, NC 27710, USA
    Cell Host Microbe 6:207-17. 2009
    ..These results demonstrate that ARIs induce changes in human peripheral blood gene expression that can be used to diagnose a viral etiology of respiratory infection and triage symptomatic individuals...
  74. pmc Bartonella species in blood of immunocompetent persons with animal and arthropod contact
    Edward B Breitschwerdt
    North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina 27606, USA
    Emerg Infect Dis 13:938-41. 2007
    ..Using PCR in conjunction with pre-enrichment culture, we detected Bartonella henselae and B. vinsonii subspecies berkhoffii in the blood of 14 immunocompetent persons who had frequent animal contact and arthropod exposure...
  75. pmc Murine typhus and febrile illness, Nepal
    Mark D Zimmerman
    Patan Hospital, Kathmandu, Nepal
    Emerg Infect Dis 14:1656-9. 2008
    ..Of patients with murine typhus, 64% were women, 86% were residents of Kathmandu, and 90% were unwell during the winter. No characteristics clearly distinguished typhus patients from those with blood culture-positive enteric fever...
  76. ncbi request reprint The etiology of febrile illness in adults presenting to Patan hospital in Kathmandu, Nepal
    David R Murdoch
    Department of Pathology, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
    Am J Trop Med Hyg 70:670-5. 2004
    ..Given the lack of reliable clinical predictors, the development of cheap and accurate diagnostic tests are likely to be of great clinical utility in this setting...