Jenny Tung

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Social environmental effects on gene regulation
    Jenny Tung
    Department of Evolutionary Anthropology, Duke University, Box 90383, Durham, NC, 27708, USA
    Cell Mol Life Sci 70:4323-39. 2013
  2. pmc Genetic effects on mating success and partner choice in a social mammal
    Jenny Tung
    Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA
    Am Nat 180:113-29. 2012
  3. pmc Social environment is associated with gene regulatory variation in the rhesus macaque immune system
    Jenny Tung
    Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA
    Proc Natl Acad Sci U S A 109:6490-5. 2012
  4. ncbi request reprint Parallel effects of genetic variation in ACE activity in baboons and humans
    Jenny Tung
    Department of Biology, Duke University, Durham, NC 27708, USA
    Am J Phys Anthropol 134:1-8. 2007
  5. doi request reprint Evolution of a malaria resistance gene in wild primates
    Jenny Tung
    Department of Biology, Duke University, North Carolina 27708, USA
    Nature 460:388-91. 2009
  6. pmc Genomic features that predict allelic imbalance in humans suggest patterns of constraint on gene expression variation
    Jenny Tung
    Department of Biology, Duke University, Durham, NC, USA
    Mol Biol Evol 26:2047-59. 2009
  7. doi request reprint Genetic evidence reveals temporal change in hybridization patterns in a wild baboon population
    J Tung
    Department of Biology, Duke University, PO Box 90338, Durham, NC 27708, USA
    Mol Ecol 17:1998-2011. 2008
  8. pmc Social environment influences the relationship between genotype and gene expression in wild baboons
    Daniel E Runcie
    Department of Biology, Duke University, Durham, NC 27708, USA
    Philos Trans R Soc Lond B Biol Sci 368:20120345. 2013
  9. doi request reprint Age at maturity in wild baboons: genetic, environmental and demographic influences
    M J E Charpentier
    Department of Biology, Duke University, PO Box 90338, Durham, NC 27708, USA
    Mol Ecol 17:2026-40. 2008
  10. ncbi request reprint Social status alters immune regulation and response to infection in macaques
    Noah Snyder-Mackler
    Department of Evolutionary Anthropology, Duke University, Durham, NC 27708, USA
    Science 354:1041-1045. 2016

Collaborators

Detail Information

Publications20

  1. pmc Social environmental effects on gene regulation
    Jenny Tung
    Department of Evolutionary Anthropology, Duke University, Box 90383, Durham, NC, 27708, USA
    Cell Mol Life Sci 70:4323-39. 2013
    ..Hence, gene regulatory studies are a promising avenue for understanding, and potentially developing strategies to address, the effects of social adversity on health. ..
  2. pmc Genetic effects on mating success and partner choice in a social mammal
    Jenny Tung
    Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA
    Am Nat 180:113-29. 2012
    ..However, the strength of the genetic effect is mediated by behavioral plasticity and social interactions, emphasizing the strong influence of social context on mating behavior in socially complex species...
  3. pmc Social environment is associated with gene regulatory variation in the rhesus macaque immune system
    Jenny Tung
    Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA
    Proc Natl Acad Sci U S A 109:6490-5. 2012
    ....
  4. ncbi request reprint Parallel effects of genetic variation in ACE activity in baboons and humans
    Jenny Tung
    Department of Biology, Duke University, Durham, NC 27708, USA
    Am J Phys Anthropol 134:1-8. 2007
    ....
  5. doi request reprint Evolution of a malaria resistance gene in wild primates
    Jenny Tung
    Department of Biology, Duke University, North Carolina 27708, USA
    Nature 460:388-91. 2009
    ..Together, our results represent the first reported association and functional characterization linking genetic variation and a complex trait in a natural population of nonhuman primates...
  6. pmc Genomic features that predict allelic imbalance in humans suggest patterns of constraint on gene expression variation
    Jenny Tung
    Department of Biology, Duke University, Durham, NC, USA
    Mol Biol Evol 26:2047-59. 2009
    ..These results suggest that the genomic distribution of functional cis-regulatory variants in the human genome is nonrandom, perhaps due to local differences in evolutionary constraint...
  7. doi request reprint Genetic evidence reveals temporal change in hybridization patterns in a wild baboon population
    J Tung
    Department of Biology, Duke University, PO Box 90338, Durham, NC 27708, USA
    Mol Ecol 17:1998-2011. 2008
    ....
  8. pmc Social environment influences the relationship between genotype and gene expression in wild baboons
    Daniel E Runcie
    Department of Biology, Duke University, Durham, NC 27708, USA
    Philos Trans R Soc Lond B Biol Sci 368:20120345. 2013
    ..We conclude that GEIs mediated by the social environment are important in the evolution and maintenance of individual differences in wild social mammals, including individual differences in responses to social stressors...
  9. doi request reprint Age at maturity in wild baboons: genetic, environmental and demographic influences
    M J E Charpentier
    Department of Biology, Duke University, PO Box 90338, Durham, NC 27708, USA
    Mol Ecol 17:2026-40. 2008
    ..Our results indicate that a complex combination of demographic, genetic, environmental, and maternal effects contribute to variation in the timing of these life-history milestones...
  10. ncbi request reprint Social status alters immune regulation and response to infection in macaques
    Noah Snyder-Mackler
    Department of Evolutionary Anthropology, Duke University, Durham, NC 27708, USA
    Science 354:1041-1045. 2016
    ..Our findings provide insight into the direct biological effects of social inequality on immune function, thus improving our understanding of social gradients in health...
  11. pmc Social status drives social relationships in groups of unrelated female rhesus macaques
    Noah Snyder-Mackler
    Department of Evolutionary Anthropology, Duke University, Durham, NC, U S A
    Anim Behav 111:307-317. 2016
    ....
  12. pmc Evolutionary genetics in wild primates: combining genetic approaches with field studies of natural populations
    Jenny Tung
    Department of Biology, Duke University, P O Box 90338, Durham NC 27708, USA
    Trends Genet 26:353-62. 2010
    ..In combination with the rich history of behavioral, ecological, and physiological work on natural primate populations, genetic approaches promise to provide a compelling picture of primate evolution in the past and in the present day...
  13. pmc Resource base influences genome-wide DNA methylation levels in wild baboons (Papio cynocephalus)
    Amanda J Lea
    Department of Biology, Duke University, Box 90338, Durham, NC, 27708, USA
    Mol Ecol 25:1681-96. 2016
    ..Together, our findings support a role for DNA methylation in mediating ecological effects on phenotypic traits in the wild and emphasize the dynamic environmental sensitivity of DNA methylation levels across the life course. ..
  14. pmc Cumulative early life adversity predicts longevity in wild baboons
    Jenny Tung
    Department of Evolutionary Anthropology, Box 90383, Duke University, Durham, North Carolina 27708, USA
    Nat Commun 7:11181. 2016
    ..Our results provide powerful evidence for the developmental origins of health and disease and indicate that close ties between early adversity and survival arise even in the absence of health habit and health care-related explanations. ..
  15. pmc Self-organizing dominance hierarchies in a wild primate population
    Mathias Franz
    Department of Biology, Duke University, Durham, NC, USA
    Proc Biol Sci 282:. 2015
    ....
  16. pmc Developmental constraints in a wild primate
    Amanda J Lea
    Department of Biology, Duke University, Durham, North Carolina 27708
    Am Nat 185:809-21. 2015
    ..Together, these data suggest that early adversity carries lifelong costs, which is consistent with the developmental constraints hypothesis...
  17. pmc Changes in gene expression associated with reproductive maturation in wild female baboons
    Courtney C Babbitt
    Department of Biology, Duke University
    Genome Biol Evol 4:102-9. 2012
    ....
  18. pmc Efficient Genome-Wide Sequencing and Low-Coverage Pedigree Analysis from Noninvasively Collected Samples
    Noah Snyder-Mackler
    Department of Evolutionary Anthropology, Duke University, Durham, North Carolina
    Genetics 203:699-714. 2016
    ..The lab protocol and software ("WHODAD") are freely available at www.tung-lab.org/protocols-and-software.html and www.xzlab.org/software.html, respectively. ..
  19. pmc A Flexible, Efficient Binomial Mixed Model for Identifying Differential DNA Methylation in Bisulfite Sequencing Data
    Amanda J Lea
    Department of Biology, Duke University, Durham, North Carolina, United States of America
    PLoS Genet 11:e1005650. 2015
    ..MACAU is freely available at www.xzlab.org/software.html. ..
  20. pmc RNA-seq: impact of RNA degradation on transcript quantification
    Irene Gallego Romero
    Department of Human Genetics, University of Chicago, 920 E 58th St, CLSC 317, Chicago, IL 60637, USA
    BMC Biol 12:42. 2014
    ..Yet, low quality samples (for example, samples collected in the course of fieldwork) are at times the sole means of addressing specific questions...