Mark P Steele
Affiliation: Duke University Medical Center
- Clinical and pathologic features of familial interstitial pneumoniaMark P Steele
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA
Am J Respir Crit Care Med 172:1146-52. 2005..Several lines of evidence suggest that genetic factors and environmental exposures play a role in the development of pulmonary fibrosis...
- Familial idiopathic interstitial pneumonia: histopathology and survival in 30 patientsKevin O Leslie
Department of Pathology, Mayo Clinic Arizona, 13400 East Shea Blvd, Scottsdale, AZ 85259, USA
Arch Pathol Lab Med 136:1366-76. 2012..Prevailing wisdom suggests that the histopathology of F-IIP is indistinguishable from that of idiopathic pulmonary fibrosis, namely, usual interstitial pneumonia (UIP)...
- Bayesian probit regression model for the diagnosis of pulmonary fibrosis: proof-of-principleEric B Meltzer
Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Duke University Medical Center, Durham, North Carolina, USA
BMC Med Genomics 4:70. 2011..The accurate diagnosis of idiopathic pulmonary fibrosis (IPF) is a major clinical challenge. We developed a model to diagnose IPF by applying Bayesian probit regression (BPR) modelling to gene expression profiles of whole lung tissue...
- Pathologic correlates of bronchiolitis obliterans syndrome in pulmonary retransplant recipientsTereza Martinu
Duke University Medical Center, Box 3876, Durham, NC 27710, USA
Chest 129:1016-23. 2006..Patients undergoing pulmonary retransplantation for BOS provide a unique opportunity to investigate these relationships...
- Pulmonary fibrosis: thinking outside of the lungStavros Garantziotis
Department of Medicine at Duke University Medical Center, Durham, North Carolina 27710, USA
J Clin Invest 114:319-21. 2004..Previous mechanistic research has focused on the local fibroproliferative process in the lung. However, emerging evidence suggests that circulating cells of hematopoietic origin play a crucial role in the pathogenesis of this disease...
- Aspergillus fumigatus empyema, arthritis, and calcaneal osteomyelitis in a lung transplant patient successfully treated with posaconazoleBarbara Alexander Lodge
Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
J Clin Microbiol 42:1376-8. 2004..Marked clinical improvement occurred within 6 weeks of initiation of posaconazole therapy; after 6 months, infection had resolved at all sites. The patient has had no recurrence of infection...
- Delay of CMV infection in high-risk CMV mismatch lung transplant recipients due to prophylaxis with oral ganciclovirScott M Palmer
Department of Medicine, Division of Pulmonary and Critical Care, Duke University Medical Center, Durham, NC, USA
Clin Transplant 18:179-85. 2004..A larger prospective randomized study is needed to confirm the benefits of oral ganciclovir on CMV prevention...
- Improved lung allograft function after fundoplication in patients with gastroesophageal reflux disease undergoing lung transplantationR Duane Davis
Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
J Thorac Cardiovasc Surg 125:533-42. 2003..Although alloimmune events are important, nonimmune events, such as gastroesophageal reflux, might contribute to lung injury and the development of bronchiolitis obliterans syndrome...
- Genetic predisposition to respiratory diseases: infiltrative lung diseasesMark P Steele
Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University Medical Center, Durham, NC 27710, USA
Respiration 74:601-8. 2007..Further insight into these areas may lead to new therapeutic interventions...
- Survival of lung transplant patients with cystic fibrosis harboring panresistant bacteria other than Burkholderia cepacia, compared with patients harboring sensitive bacteriaDenis Hadjiliadis
Department of Medicine, Division of Pulmonary Critical Care, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 10104, USA
J Heart Lung Transplant 26:834-8. 2007..The impact of panresistant bacteria, other than Burkholderia cepacia, on the survival after lung transplantation in patients with cystic fibrosis (CF) remains controversial...
- Molecular mechanisms in progressive idiopathic pulmonary fibrosisMark P Steele
Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
Annu Rev Med 64:265-76. 2013..A common variant in mucin 5B predisposes to both familial and sporadic IPF and is present in the majority of cases, indicating sporadic IPF occurs in those with genetic predisposition...
- Familial pulmonary fibrosis in the United StatesMomen M Wahidi
Duke University Medical Center, Durham, NC 27710, USA
Chest 121:30S. 2002
- Successful bilateral lung transplant outcomes in recipients 61 years of age and olderScott M Palmer
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Transplantation 81:862-5. 2006..We hypothesize that BLT offers comparable, if not superior, clinical outcomes to SLT in all patients independent of recipient age...
- Posttransplant lymphoproliferative disorder: incidence, presentation, and response to treatment in lung transplant recipientsB Diane Reams
Department of Pharmacy, Duke University Medical Center, Durham, NC 27710, USA
Chest 124:1242-9. 2003..In this report, we define the incidence, clinical features at presentation, and response to treatment of all cases of PTLD observed at our institution over a 10-year period, including four patients who received treatment with rituximab...
- Gene expression profiling of familial and sporadic interstitial pneumoniaIvana V Yang
Laboratory of Respiratory Biology, National Institute of Environmental Health Sciences, P O Box 12233, MD B3 08, Research Triangle Park, NC 27909, USA
Am J Respir Crit Care Med 175:45-54. 2007..Both the genetics and the histologic type of IIP play a role in the etiology and pathogenesis of interstitial lung disease, but transcriptional signatures of these subtypes are unknown...
- Gastroesophageal reflux disease in lung transplant recipientsDenis Hadjiliadis
Lung Transplant Program, University of Toronto, Toronto, Canada
Clin Transplant 17:363-8. 2003..A link between gastric aspiration and post-transplant lung dysfunction has been suggested, but little is known about the significance of gastroesophageal reflux disease (GERD) after lung transplantation...
- Pre-transplant panel reactive antibody in lung transplant recipients is associated with significantly worse post-transplant survival in a multicenter studyDenis Hadjiliadis
Department of Medicine, Division of Respirology, Toronto General Hospital, Toronto, Ontario, Canada
J Heart Lung Transplant 24:S249-54. 2005..The effect of these antibodies is less clear in lung transplant recipients, although previous studies have suggested an increased incidence of allograft dysfunction...
- Outcome of lung transplant patients admitted to the medical ICUDenis Hadjiliadis
Toronto Lung Transplant Program, Toronto, ON, Canada
Chest 125:1040-5. 2004..Little is known about the epidemiology, clinical outcomes, and risk factors for survival among lung transplant recipients admitted to the ICU...
- Physician subsidies for tobacco advertisingVictor L Roggli
Am J Respir Crit Care Med 173:246. 2006