Mark Oldham

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Investigation of the feasibility of relative 3D dosimetry in the Radiologic Physics Center Head and Neck IMRT phantom using presage/optical-CT
    Harshad Sakhalkar
    Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Med Phys 36:3371-7. 2009
  2. pmc A quality assurance method that utilizes 3D dosimetry and facilitates clinical interpretation
    Mark Oldham
    Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Int J Radiat Oncol Biol Phys 84:540-6. 2012
  3. ncbi request reprint Three-dimensional imaging of whole rodent organs using optical computed and emission tomography
    Mark Oldham
    Duke University Medical Center, Department of Radiation Oncology and Biomedical Engineering, Durham, North Carolina 27710, USA
    J Biomed Opt 12:014009. 2007
  4. pmc Optical clearing of unsectioned specimens for three-dimensional imaging via optical transmission and emission tomography
    Mark Oldham
    Duke University Medical Center, Department of Radiation Oncology, Durham, North Carolina 27710, USA
    J Biomed Opt 13:021113. 2008
  5. pmc An investigation of the accuracy of an IMRT dose distribution using two- and three-dimensional dosimetry techniques
    Mark Oldham
    Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Med Phys 35:2072-80. 2008
  6. pmc A practical three-dimensional dosimetry system for radiation therapy
    Pengyi Guo
    Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Med Phys 33:3962-72. 2006
  7. ncbi request reprint Cone-beam-CT guided radiation therapy: technical implementation
    Daniel Letourneau
    Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI, USA
    Radiother Oncol 75:279-86. 2005
  8. pmc Commissioning a small-field biological irradiator using point, 2D, and 3D dosimetry techniques
    Joseph Newton
    Department of Radiation Oncology, Duke University, Durham, North Carolina 27710, USA
    Med Phys 38:6754-62. 2011
  9. pmc Three-dimensional imaging of xenograft tumors using optical computed and emission tomography
    Mark Oldham
    Department of Radiation Oncology Physics, and Biomedical Engineering, Duke University Medical Center, Durham, North Carolina 27710, USA
    Med Phys 33:3193-202. 2006
  10. pmc Commissioning a CT-compatible LDR tandem and ovoid applicator using Monte Carlo calculation and 3D dosimetry
    Justus Adamson
    Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
    Med Phys 39:4515-23. 2012

Detail Information

Publications34

  1. pmc Investigation of the feasibility of relative 3D dosimetry in the Radiologic Physics Center Head and Neck IMRT phantom using presage/optical-CT
    Harshad Sakhalkar
    Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Med Phys 36:3371-7. 2009
    ..The potential to extend the RPC IMRT credentialing procedure to 3D may be feasible provided accurate calibration to dose (Gy) and robustness to shipping stress are demonstrated...
  2. pmc A quality assurance method that utilizes 3D dosimetry and facilitates clinical interpretation
    Mark Oldham
    Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Int J Radiat Oncol Biol Phys 84:540-6. 2012
    ..Also to apply the method to investigate the dosimetric efficacy of base-of-skull (BOS) intensity-modulated radiotherapy (IMRT) treatment...
  3. ncbi request reprint Three-dimensional imaging of whole rodent organs using optical computed and emission tomography
    Mark Oldham
    Duke University Medical Center, Department of Radiation Oncology and Biomedical Engineering, Durham, North Carolina 27710, USA
    J Biomed Opt 12:014009. 2007
    ....
  4. pmc Optical clearing of unsectioned specimens for three-dimensional imaging via optical transmission and emission tomography
    Mark Oldham
    Duke University Medical Center, Department of Radiation Oncology, Durham, North Carolina 27710, USA
    J Biomed Opt 13:021113. 2008
    ..We review recent developments in optical-CT and optical-ECT, and compatible "fluorescence-friendly" optical clearing protocols...
  5. pmc An investigation of the accuracy of an IMRT dose distribution using two- and three-dimensional dosimetry techniques
    Mark Oldham
    Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina 27710, USA
    Med Phys 35:2072-80. 2008
    ..In conclusion, for the complex IMRT plan studied, and in the absence of inhomogeneities, the ECLIPSE dose calculation was found to agree with both independent measurements, to within 3%, 3 mm gamma criteria...
  6. pmc A practical three-dimensional dosimetry system for radiation therapy
    Pengyi Guo
    Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Med Phys 33:3962-72. 2006
    ....
  7. ncbi request reprint Cone-beam-CT guided radiation therapy: technical implementation
    Daniel Letourneau
    Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI, USA
    Radiother Oncol 75:279-86. 2005
    ..In preparation for clinical implementation, phantom and patient imaging studies were conducted to determine the irradiation parameters that would trade-off image quality, patient dose and scanning time...
  8. pmc Commissioning a small-field biological irradiator using point, 2D, and 3D dosimetry techniques
    Joseph Newton
    Department of Radiation Oncology, Duke University, Durham, North Carolina 27710, USA
    Med Phys 38:6754-62. 2011
    ..This work incorporates point, 2D, and 3D measurements to determine output factors (OF), percent-depth-dose (PDD) and dose profiles at multiple depths...
  9. pmc Three-dimensional imaging of xenograft tumors using optical computed and emission tomography
    Mark Oldham
    Department of Radiation Oncology Physics, and Biomedical Engineering, Duke University Medical Center, Durham, North Carolina 27710, USA
    Med Phys 33:3193-202. 2006
    ..In summary, optical-CT and optical-ECT, when combined with new optical clearing techniques, represent powerful new imaging modalities with potential for providing unique information on the structure and function of tumors...
  10. pmc Commissioning a CT-compatible LDR tandem and ovoid applicator using Monte Carlo calculation and 3D dosimetry
    Justus Adamson
    Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
    Med Phys 39:4515-23. 2012
    ..To determine the geometric and dose attenuation characteristics of a new commercially available CT-compatible LDR tandem and ovoid (T&O) applicator using Monte Carlo calculation and 3D dosimetry...
  11. pmc A comprehensive method for optical-emission computed tomography
    Andrew Thomas
    Duke University, Durham, NC, USA
    Phys Med Biol 55:3947-57. 2010
    ..The corrected reconstruction showed agreement throughout the verification image with only slight variations ( approximately 5%). Final experiments demonstrate the correction in tissue as applied to a tumor with constitutive RFP...
  12. pmc A comprehensive investigation of the accuracy and reproducibility of a multitarget single isocenter VMAT radiosurgery technique
    Andrew Thomas
    Duke University Medical Center, Durham, North Carolina 27710
    Med Phys 40:121725. 2013
    ..This work presents an investigation into the consistency and reproducibility of this new treatment technique using a comprehensive commissioned high-resolution 3D dosimetry system (PRESAGE(®)∕Optical-CT)...
  13. pmc On the feasibility of polyurethane based 3D dosimeters with optical CT for dosimetric verification of low energy photon brachytherapy seeds
    Justus Adamson
    Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710
    Med Phys 41:071705. 2014
    ..To investigate the feasibility of and challenges yet to be addressed to measure dose from low energy (effective energy <50 keV) brachytherapy sources (Pd-103, Cs-131, and I-125) using polyurethane based 3D dosimeters with optical CT...
  14. pmc On the need for comprehensive validation of deformable image registration, investigated with a novel 3-dimensional deformable dosimeter
    Titania Juang
    Medical Physics Graduate Program, Duke University Medical Center, Durham, North Carolina 27710, USA
    Int J Radiat Oncol Biol Phys 87:414-21. 2013
    ..To introduce and evaluate a novel deformable 3-dimensional (3D) dosimetry system (Presage-Def/Optical-CT) and its application toward investigating the accuracy of dose deformation in a commercial deformable image registration (DIR) package...
  15. ncbi request reprint Digital tomosynthesis with an on-board kilovoltage imaging device
    Devon J Godfrey
    Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
    Int J Radiat Oncol Biol Phys 65:8-15. 2006
    ..To generate on-board digital tomosynthesis (DTS) and reference DTS images for three-dimensional image-guided radiation therapy (IGRT) as an alternative to conventional portal imaging or on-board cone-beam computed tomography (CBCT)...
  16. pmc Toward acquiring comprehensive radiosurgery field commissioning data using the PRESAGE/optical-CT 3D dosimetry system
    Corey Clift
    Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
    Phys Med Biol 55:1279-93. 2010
    ..The advantages of the PRESAGE system for small field dosimetry include 3D measurements, negligible volume averaging, directional insensitivity, an absence of beam perturbations, energy and dose rate independence...
  17. pmc Investigation into the feasibility of using PRESAGE/optical-CT dosimetry for the verification of gating treatments
    Samuel L Brady
    Medical Physics Graduate Program, Duke University, Durham, NC 27710, USA
    Phys Med Biol 55:2187-201. 2010
    ..The capability of the Varian gating system to compensate for motion in this treatment scenario was demonstrated...
  18. ncbi request reprint Physics and imaging for targeting of oligometastases
    Fang Fang Yin
    Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA
    Semin Radiat Oncol 16:85-101. 2006
    ....
  19. pmc Commissioning and benchmarking a 3D dosimetry system for clinical use
    Andrew Thomas
    Duke University Medical Center, Durham, North Carolina 27710, USA
    Med Phys 38:4846-57. 2011
    ..The DLOS/PRESAGE system has recently been commissioned and benchmarked for clinical use and, in particular, for verification and commissioning of complex radiation treatments...
  20. ncbi request reprint Cone-beam-CT guided radiation therapy: A model for on-line application
    Mark Oldham
    Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI, USA
    Radiother Oncol 75:271-8. 2005
    ....
  21. pmc A method to correct for stray light in telecentric optical-CT imaging of radiochromic dosimeters
    Andrew Thomas
    Duke University Medical Center, Durham, NC, USA
    Phys Med Biol 56:4433-51. 2011
    ..Correcting for stray light extended the dynamic range of the system from ∼30 to ∼60 dB. The correction should be used when measurements need to be accurate within 3%...
  22. pmc A method to correct for spectral artifacts in optical-CT dosimetry
    Andrew Thomas
    Duke University, Durham, NC, USA
    Phys Med Biol 56:3403-16. 2011
    ..Physical filters may be less viable if they introduce strong sensitivity to Schlieren bands in the dosimeters...
  23. ncbi request reprint Evaluation of a 2D diode array for IMRT quality assurance
    Daniel Letourneau
    Department of Radiation Oncology, William Beaumont Hospital, 3601 W Thirteen Mile Road, Royal Oak, MI 48073, USA
    Radiother Oncol 70:199-206. 2004
    ..The goal of this work is to evaluate the dosimetric characteristics of a new 2D diode array (MapCheck from Sun Nuclear Corporation, Melbourne, Florida) and assess the role it can play in routine IMRT QA...
  24. pmc Optical-CT gel-dosimetry. II: Optical artifacts and geometrical distortion
    Mark Oldham
    William Beaumont Hospital, Royal Oak, Michigan 48073, USA
    Med Phys 31:1093-104. 2004
    ..For accurate reconstruction of absolute attenuation coefficients, correction strategies are essential...
  25. pmc On the feasibility of comprehensive high-resolution 3D remote dosimetry
    Titania Juang
    Medical Physics Graduate Program, Duke University Medical Center, Durham, North Carolina 27705 and Department of Radiation Oncology Physics, Duke University Medical Center, Durham, North Carolina 27710
    Med Phys 41:071706. 2014
    ..In remote dosimetry, dosimeters are shipped out from a central base institution to a remote institution for irradiation, then shipped back to the base institution for subsequent readout and analysis...
  26. pmc On the feasibility of optical-CT imaging in media of different refractive index
    Leith Rankine
    Medical Physics Graduate Program, Duke University, Durham, North Carolina 27710, USA
    Med Phys 40:051701. 2013
    ..Achieving accurate optical-CT 3D dosimetry without the use of viscous refractive index (RI) matching fluids would greatly increase convenience...
  27. pmc Investigations into the feasibility of optical-CT 3D dosimetry with minimal use of refractively matched fluids
    Kelsey Chisholm
    Medical Physics Graduate Program, Duke University, Durham, North Carolina 27710
    Med Phys 42:2607-14. 2015
    ..This work investigates the feasibility of solid-tank optical-CT imaging for 3D dosimetry through computer simulation...
  28. pmc An investigation of PRESAGE® 3D dosimetry for IMRT and VMAT radiation therapy treatment verification
    Jake Jackson
    Duke Universty, Durham, NC, USA
    Phys Med Biol 60:2217-30. 2015
    ..Finally, PRESAGE(®) is observed to be a useful method of 3D verification when careful consideration is given to the temporal stability and imaging protocols for the specific formulation used...
  29. ncbi request reprint Predicting radiotherapy-induced cardiac perfusion defects
    Shiva K Das
    Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Med Phys 32:19-27. 2005
    ..In conclusion, the nonparametric LDA model appears to be a more accurate predictor of radiotherapy-induced left ventricular perfusion defects than commonly used parametric models...
  30. pmc X-Ray Psoralen Activated Cancer Therapy (X-PACT)
    Mark Oldham
    Dept of Radiation Oncology, Duke University Medical Center, Durham, North Carolina, United States of America
    PLoS ONE 11:e0162078. 2016
    ....
  31. pmc Optical-CT gel-dosimetry I: basic investigations
    Mark Oldham
    William Beaumont Hospital, Royal Oak, Michigan 48073 6769, USA
    Med Phys 30:623-34. 2003
    ..The model utilizes Mie scattering theory and requires knowledge of the variation of the particle size distribution with dose. The latter was determined here using the technique of dynamic-light-scattering...