Lars H Lund

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. doi request reprint Association of spironolactone use with all-cause mortality in heart failure: a propensity scored cohort study
    Lars H Lund
    Department of Medicine, Karolinska Institutet, Stockholm, Sweden mail
    Circ Heart Fail 6:174-83. 2013
  2. doi request reprint Prevalence, correlates, and prognostic significance of QRS prolongation in heart failure with reduced and preserved ejection fraction
    Lars H Lund
    Department of Medicine, Karolinska Institutet, 17177 Stockholm, Sweden
    Eur Heart J 34:529-39. 2013
  3. doi request reprint Association between use of renin-angiotensin system antagonists and mortality in patients with heart failure and preserved ejection fraction
    Lars H Lund
    Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden
    JAMA 308:2108-17. 2012
  4. doi request reprint Derived and displayed power consumption, flow, and pulsatility over a range of HeartMate II left ventricular assist device settings
    Lars H Lund
    Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
    ASAIO J 58:183-90. 2012
  5. ncbi request reprint Peak VO2 in elderly patients with heart failure
    Lars H Lund
    Division of Cardiology and Medicine, Karolinska Institute and Karolinska University Hospital, 171 76 Stockholm, Sweden
    Int J Cardiol 125:166-71. 2008
  6. pmc Growth hormone resistance in severe heart failure resolves after cardiac transplantation
    Lars H Lund
    Department of Cardiology, Karolinska University Hospital, N305, Stockholm, Sweden
    Eur J Heart Fail 11:525-8. 2009
  7. pmc Ghrelin resistance occurs in severe heart failure and resolves after heart transplantation
    Lars H Lund
    Section for Heart Failure, Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
    Eur J Heart Fail 11:789-94. 2009
  8. doi request reprint Patient selection for left ventricular assist devices
    Lars H Lund
    Department of Cardiology, Section for Heart Failure, Karolinska University Hospital, N305 171 76 Stockholm, Sweden
    Eur J Heart Fail 12:434-43. 2010
  9. pmc Myocardial recovery in peri-partum cardiomyopathy after continuous flow left ventricular assist device
    Lars H Lund
    Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
    J Cardiothorac Surg 6:150. 2011
  10. doi request reprint HFpEF and HFrEF Display Different Phenotypes as Assessed by IGF-1 and IGFBP-1
    Ulrika Ljung Faxén
    Department of Anesthesia and Intensive Care, Karolinska University Hospital, Stockholm, Sweden Department of Medicine, Stockholm, Karolinska Institutet, Sweden Electronic address
    J Card Fail . 2016

Collaborators

Detail Information

Publications55

  1. doi request reprint Association of spironolactone use with all-cause mortality in heart failure: a propensity scored cohort study
    Lars H Lund
    Department of Medicine, Karolinska Institutet, Stockholm, Sweden mail
    Circ Heart Fail 6:174-83. 2013
    ..We tested the hypothesis that spironolactone is associated with reduced mortality also in a broad unselected contemporary population with HF and reduced ejection fraction, in particular New York Heart Association (NYHA) I-II...
  2. doi request reprint Prevalence, correlates, and prognostic significance of QRS prolongation in heart failure with reduced and preserved ejection fraction
    Lars H Lund
    Department of Medicine, Karolinska Institutet, 17177 Stockholm, Sweden
    Eur Heart J 34:529-39. 2013
    ..The rationale for cardiac resynchronization therapy (CRT) in preserved EF is unknown. The aim was to determine the prevalence of, correlates with, and prognostic impact of QRS prolongation in HF with reduced and preserved EF...
  3. doi request reprint Association between use of renin-angiotensin system antagonists and mortality in patients with heart failure and preserved ejection fraction
    Lars H Lund
    Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden
    JAMA 308:2108-17. 2012
    ..Three randomized trials of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (ie, renin-angiotensin system [RAS] antagonists) did not reach primary end points but may have had selection bias or been underpowered...
  4. doi request reprint Derived and displayed power consumption, flow, and pulsatility over a range of HeartMate II left ventricular assist device settings
    Lars H Lund
    Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
    ASAIO J 58:183-90. 2012
    ..These findings have implications for clinicians attempting to optimize settings and assess pump and native heart function...
  5. ncbi request reprint Peak VO2 in elderly patients with heart failure
    Lars H Lund
    Division of Cardiology and Medicine, Karolinska Institute and Karolinska University Hospital, 171 76 Stockholm, Sweden
    Int J Cardiol 125:166-71. 2008
    ..This review examines the physiology of aging and the clinical utility of exercise testing in elderly patients with heart failure...
  6. pmc Growth hormone resistance in severe heart failure resolves after cardiac transplantation
    Lars H Lund
    Department of Cardiology, Karolinska University Hospital, N305, Stockholm, Sweden
    Eur J Heart Fail 11:525-8. 2009
    ..Whether GH resistance resolves post HTx is unknown. We aimed to confirm that HF is associated with GH resistance and to test the hypothesis that GH resistance resolves post HTx...
  7. pmc Ghrelin resistance occurs in severe heart failure and resolves after heart transplantation
    Lars H Lund
    Section for Heart Failure, Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
    Eur J Heart Fail 11:789-94. 2009
    ..Ghrelin is a novel appetite-stimulating hormone. The aim was to determine the role of ghrelin in regulating appetite, food intake, and body composition in HF and post-HTx...
  8. doi request reprint Patient selection for left ventricular assist devices
    Lars H Lund
    Department of Cardiology, Section for Heart Failure, Karolinska University Hospital, N305 171 76 Stockholm, Sweden
    Eur J Heart Fail 12:434-43. 2010
    ..This review summarizes recent reports of predictors of poor outcomes and provides an overview of selection for LVAD therapy...
  9. pmc Myocardial recovery in peri-partum cardiomyopathy after continuous flow left ventricular assist device
    Lars H Lund
    Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
    J Cardiothorac Surg 6:150. 2011
    ..We describe the clinical course of a patient with severe peri-partum cardiomyopathy (PPCM) rescued with a continuous flow LVAD, who experienced recovery and explantation. We discuss assessment of and criteria for recovery...
  10. doi request reprint HFpEF and HFrEF Display Different Phenotypes as Assessed by IGF-1 and IGFBP-1
    Ulrika Ljung Faxén
    Department of Anesthesia and Intensive Care, Karolinska University Hospital, Stockholm, Sweden Department of Medicine, Stockholm, Karolinska Institutet, Sweden Electronic address
    J Card Fail . 2016
    ..Insulin-like growth factor 1 (IGF-1) mediates growth hormone effects and IGF binding protein 1 (IGFBP-1) regulates IGF-1 activity. We tested the hypothesis that HFpEF and HFrEF are similar with regard to IGF-1 and IGFBP-1...
  11. doi request reprint Triage of patients with moderate to severe heart failure: who should be referred to a heart failure center?
    Tonje Thorvaldsen
    Department of Medicine, Karolinska Institutet, Stockholm, Sweden Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
    J Am Coll Cardiol 63:661-71. 2014
    ..The purpose of this study was to evaluate simple criteria for referral of patients from the general practitioner to a heart failure (HF) center...
  12. doi request reprint Peripheral extracorporeal membrane oxygenation as short-term right ventricular support after HeartWare left ventricular assist device implantation
    Magnus Dalén
    Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    ASAIO J 59:523-5. 2013
    ..We describe the use of peripheral venoarterial extracorporeal membrane oxygenation as a short-term treatment of right heart failure after HeartWare LVAD implantation...
  13. doi request reprint Gender, underutilization of cardiac resynchronization therapy, and prognostic impact of QRS prolongation and left bundle branch block in heart failure
    Cecilia Linde
    Department of Medicine, Karolinska Institutet, Stockholm 17177, Sweden Department of Cardiology, N205, Karolinska University Hospital, Solna, Stockholm 17176, Sweden
    Europace 17:424-31. 2015
    ..We tested the hypotheses that (i) CRT is more underutilized and (ii) QRS prolongation and left bundle branch block (LBBB) are more harmful in women...
  14. doi request reprint Age, prognostic impact of QRS prolongation and left bundle branch block, and utilization of cardiac resynchronization therapy: findings from 14,713 patients in the Swedish Heart Failure Registry
    Lars H Lund
    Karolinska Institutet, Department of Medicine, Stockholm, Sweden Karolinska University Hospital, Department of Medicine, Unit of Cardiology, N305, 17176, Stockholm, Sweden
    Eur J Heart Fail 16:1073-81. 2014
    ..We tested the hypotheses that in the elderly: (i) IVCD and LBBB are more prevalent, (ii) IVCD and LBBB are more harmful, and (iii) CRT is underutilized...
  15. ncbi request reprint Validation of peak exercise oxygen consumption and the Heart Failure Survival Score for serial risk stratification in advanced heart failure
    Lars H Lund
    Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
    Am J Cardiol 95:734-41. 2005
    ..Peak VO2 and the HFSS can be successfully used for serial evaluation of mortality risk in ambulatory patients who have advanced heart failure...
  16. doi request reprint Association of candesartan vs losartan with all-cause mortality in patients with heart failure
    Maria Eklind-Cervenka
    Department of Cardiology, South Hospital, Stockholm, Sweden
    JAMA 305:175-82. 2011
    ..Different agents have different affinity for the AT(1) receptor and may have different clinical effects, but have not been tested against each other in HF...
  17. doi request reprint Extracorporeal membrane oxygenation as a rescue of intractable ventricular fibrillation and bridge to heart transplantation
    Thomas Fux
    Department of Cardiology, Section for Heart Failure, Karolinska University Hospital, N305, 171 76 Stockholm, Sweden
    Eur J Heart Fail 12:301-4. 2010
    ....
  18. doi request reprint Changes in natriuretic peptides after acute hospital presentation for heart failure with preserved ejection fraction: A feasible surrogate trial endpoint? A report from the prospective Karen study
    Gianluigi Savarese
    Karolinska Institutet, Department of Medicine, Stockholm, Sweden Electronic address
    Int J Cardiol 226:65-70. 2017
    ..The aim of the current study was to evaluate whether a reduction in natriuretic peptides (NP) between acute hospital presentation to stable follow-up is associated with improved mortality and morbidity...
  19. doi request reprint New York Heart Association functional class, QRS duration, and survival in heart failure with reduced ejection fraction: implications for cardiac resychronization therapy
    Frieder Braunschweig
    Karolinska Institutet, Department of Medicine, Stockholm, Sweden
    Eur J Heart Fail . 2016
    ..This study assessed the relationship between NYHA class, QRS duration, and survival in a nationwide HF registry...
  20. doi request reprint Cardiovascular Diseases in ~30,000 Patients in the Swedish Dementia Registry
    Pavla Cermáková
    Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division for Neurogeriatrics, Huddinge, Sweden
    J Alzheimers Dis 48:949-58. 2015
    ..Cardiovascular diseases are leading causes of death and patients with dementia are often affected by them...
  21. doi request reprint Planned repetitive use of levosimendan for heart failure in cardiology and internal medicine in Sweden
    Tonje Thorvaldsen
    Karolinska Institutet, Department of Medicine, Unit of Cardiology, 17177 Stockholm, Sweden Karolinska University Hospital, Department of Cardiology, 17176 Stockholm, Sweden
    Int J Cardiol 175:55-61. 2014
    ..The aim was to assess the use of levosimendan vs. conventional inotropes and the use as planned repetitive vs. acute treatment, in Sweden...
  22. pmc Modifications of skeletal muscle ryanodine receptor type 1 and exercise intolerance in heart failure
    Eric Rullman
    Department of Cardiology, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    J Heart Lung Transplant 32:925-9. 2013
    ..However, it is not known whether similar remodeling of RyR1 in skeletal muscle occurs in patients with heart failure, and if this is associated with impairment of physical activity...
  23. doi request reprint Women have better long-term prognosis than men after cardiac resynchronization therapy
    Stanislava Zabarovskaja
    Section for Heart Failure, Department of Cardiology, Karolinska University Hospital, 17176 Stockholm, Sweden
    Europace 14:1148-55. 2012
    ..However, CRT may be under-utilized in women and data on long-term follow-up are still scarce. The aim was to investigate long-term mortality and hospitalization and prognostic impact of gender after CRT...
  24. doi request reprint Inflammatory Biomarkers Predict Heart Failure Severity and Prognosis in Patients With Heart Failure With Preserved Ejection Fraction: A Holistic Proteomic Approach
    Camilla Hage
    From the Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden C H, C L, L H L Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden C H, C L, L H L Cardiovascular and Metabolic Diseases, Innovative Medicines and Early Development Biotech Unit, AstraZeneca R and D, Molndal, Sweden E M, L M G Département de Cardiologie and CIC IT U 804, Centre Hospitalier Universitaire de Rennes, France E D, J C D and Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Sweden L M G
    Circ Cardiovasc Genet 10:. 2017
    ..We investigated cardiovascular plasma biomarkers in HF with preserved ejection fraction and their correlation to diastolic dysfunction, functional class, pathophysiological processes, and prognosis...
  25. doi request reprint Use of evidence-based therapy and survival in heart failure in Sweden 2003-2012
    Tonje Thorvaldsen
    Karolinska Institutet, Department of Medicine, Stockholm, Sweden
    Eur J Heart Fail 18:503-11. 2016
    ..In heart failure with reduced ejection fraction, drug and device therapy improve survival. We studied contemporary trends in utilization of evidence-based therapy and associated survival...
  26. doi request reprint Reductions in N-Terminal Pro-Brain Natriuretic Peptide Levels Are Associated With Lower Mortality and Heart Failure Hospitalization Rates in Patients With Heart Failure With Mid-Range and Preserved Ejection Fraction
    Gianluigi Savarese
    From the Department of Medicine G S, C H, L H L and Department of Public Health Sciences N O, Karolinska Institutet, Stockholm, Sweden Department of Cardiology U D and Department of Medical and Health Sciences U D, Linkoping University, Sweden Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy P P F Cardiovascular and Cell Sciences Research Institute, St George s University, London, UK G M C R and IRCCS San Raffaele Pisana, Rome, Italy G M C R
    Circ Heart Fail 9:. 2016
    ..The aim was to assess whether a reduction in N-terminal pro-B-type natriuretic peptide (NT-proBNP) is associated with improved mortality/morbidity in an unselected population of HFmrEF and HFpEF patients...
  27. doi request reprint HFpEF and HFrEF exhibit different phenotypes as assessed by leptin and adiponectin
    Ulrika Ljung Faxén
    Department of Anesthesia and Intensive Care, Karolinska University Hospital, Stockholm, Sweden Department of Medicine, Stockholm, Karolinska Institutet, Sweden Electronic address
    Int J Cardiol 228:709-716. 2016
    ..Whether this profile exists in HF with preserved ejection fraction (HFpEF) is unknown. We tested the hypothesis that HFpEF and HFrEF are similar regarding concentrations of and prognostic impact of leptin and adiponectin...
  28. doi request reprint Effects of Dipeptidyl Peptidase 4 Inhibitors and Sodium-Glucose Linked coTransporter-2 Inhibitors on cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis
    Gianluigi Savarese
    Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Int J Cardiol 220:595-601. 2016
    ..The purpose of the current study was to evaluate the effects of DPP4-Is and SGLT2-Is on CV events and mortality by meta-analysis...
  29. doi request reprint Copeptin in Heart Failure, Post-Left Ventricular Assist Device and Post-Heart Transplantation
    Stanislava Zabarovskaja
    Karolinska Institute, Department of Medicine, Stockholm, Sweden Karolinska University Hospital, Department of Cardiology, Stockholm, Sweden Electronic address
    Heart Lung Circ . 2016
    ..We hypothesised that copeptin is elevated and associated with worse prognosis in HF, and that left ventricular assist device (LVAD) therapy and heart transplantation (HTx) are associated with lower levels of copeptin...
  30. ncbi request reprint Cardiac resynchronization therapy: results, challenges and perspectives for the future
    Marcus Ståhlberg
    a Department of Medicine, Karolinska Institutet, Solna, Stockholm, Sweden
    Scand Cardiovasc J 50:282-292. 2016
    ....
  31. doi request reprint Efficacy and safety of prolonged dual antiplatelet therapy: a meta-analysis of 15 randomized trials enrolling 85 265 patients
    Gianluigi Savarese
    Department of Advanced Biomedical Sciences, Federico II University, Via S Pansini 5, 80131 Naples, Italy Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden
    Eur Heart J Cardiovasc Pharmacother 2:218-28. 2016
    ..Aim of this study was to assess the effects of prolonged vs. no/short-term DAPT on myocardial infarction (MI), stroke, bleeding, and mortality...
  32. doi request reprint Association Between Use of Statins and Mortality in Patients With Heart Failure and Ejection Fraction of ≥50
    Urban Alehagen
    From the Department of Cardiology and Department of Medical and Health Sciences, Linkoping University, Linkoping, Sweden U A, U D Department of Clinical Science and Education, Karolinska Institutet, Stockholm, Sweden L B and Department of Cardiology, Karolinska University Hospital and Department of Medicine, Unit of Cardiology, Karolinska Institutet, Stockholm, Sweden M E, L H L
    Circ Heart Fail 8:862-70. 2015
    ..Therefore, statins might improve outcomes in patients with heart failure with preserved ejection fraction defined as ≥50%...
  33. doi request reprint Association between use of statins and outcomes in heart failure with reduced ejection fraction: prospective propensity score matched cohort study of 21 864 patients in the Swedish Heart Failure Registry
    Urban Alehagen
    From the Departments of Cardiology and Medical and Health Sciences, Linkoping University, Linkoping, Sweden U A, U D Departments of Clinical Science and Education L B and Medicine M E, L L, Karolinska Institutet, Stockholm, Sweden and Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden M E, L L
    Circ Heart Fail 8:252-60. 2015
    ..The aim was to determine whether statins are associated with improved outcomes in an unselected nationwide population of patients with HF with reduced ejection fraction overall and in relation to ischemic heart disease (IHD)...
  34. doi request reprint HeartWare left ventricular assist device thrombosis in aspirin non-responder
    Magnus Dalén
    Department of Molecular Medicine and Surgery, Department of Cardiothoracic Surgery and Anesthesiology, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden
    Asian Cardiovasc Thorac Ann 22:203-4. 2014
    ..There is a need for clinical trials determining optimal antiplatelet therapy in patients supported with left ventricular assist devices, and consensus regarding modification of antiplatelet therapy after device thrombosis. ..
  35. doi request reprint Change in blood pressure during hospitalisation for acute heart failure predicts mortality
    Per Svensson
    Department of Emergency Medicine, Karolinska University Hospital Solna, Stockholm, Sweden
    Scand Cardiovasc J 44:325-30. 2010
    ..The primary objective was to study the impact of the change in BP during a hospitalisation for acute HF on prognosis...
  36. doi request reprint Heart failure in Tanzania and Sweden: Comparative characterization and prognosis in the Tanzania Heart Failure (TaHeF) study and the Swedish Heart Failure Registry (SwedeHF)
    Abel Makubi
    Cardiology Unit, Department of Medicine, Karolinska Institutet, 17177 Stockholm, Sweden School of Medicine, Muhimbili University of Health and Allied Sciences, PO Box 65001, Dar es Salaam, Tanzania Jakaya Kikwete Cardiac Institute, PO Box 65000, Dar es Salaam, Tanzania Electronic address
    Int J Cardiol 220:750-8. 2016
    ..Heart failure (HF) in developing countries is poorly described. We compare characteristics and prognosis of HF in Tanzania vs. Sweden...
  37. doi request reprint Increases in Cardiac Output and Oxygen Consumption During Enhanced External Counterpulsation
    Magnus Ahlbom
    Karolinska Institutet, School of Medicine, Stockholm, Sweden
    Heart Lung Circ 25:1133-1136. 2016
    ..direct EECP effects (diastolic augmentation, DA-ratio), and their relation to cardiac index (CI) during EECP are unknown...
  38. doi request reprint Efficacy and Safety of Novel Oral Anticoagulants in Patients With Atrial Fibrillation and Heart Failure: A Meta-Analysis
    Gianluigi Savarese
    Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy Cardiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    JACC Heart Fail 4:870-880. 2016
    ..This study investigated the efficacy and safety of novel oral anticoagulants (NOACs) in patients with atrial fibrillation (AF) and heart failure (HF) by a meta-analysis...
  39. doi request reprint Association between renin-angiotensin system antagonist use and mortality in heart failure with severe renal insufficiency: a prospective propensity score-matched cohort study
    Magnus Edner
    Department of Medicine, Unit of Cardiology, Karolinska Institutet, 17177 Stockholm, Sweden
    Eur Heart J 36:2318-26. 2015
    ..However, severe renal insufficiency was an exclusion criterion in trials. We tested the hypothesis that RAS antagonists are associated with reduced mortality also in HF with severe renal insufficiency...
  40. doi request reprint Adaptive cardiovascular hormones in a spectrum of heart failure phenotypes
    Stanislava Zabarovskaja
    Karolinska Institute, Department of Medicine, Stockholm, Sweden Karolinska University Hospital, Department of Cardiology, Stockholm, Sweden
    Int J Cardiol 189:6-11. 2015
    ....
  41. doi request reprint Comparative associations between angiotensin converting enzyme inhibitors, angiotensin receptor blockers and their combination, and outcomes in patients with heart failure and reduced ejection fraction
    Gianluigi Savarese
    Karolinska Institute, Department of Medicine, Cardiology Unit, Stockholm, Sweden Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy Electronic address
    Int J Cardiol 199:415-23. 2015
    ..ACE-I and their combination in unselected populations. The purpose of this study was to compare the associations between the use of ACE-I, ARB and their combination, and outcomes in HFREF...
  42. doi request reprint Utility of the Seattle Heart Failure Model in patients with cardiac resynchronization therapy and implantable cardioverter defibrillator referred for heart transplantation
    Ulrik Sartipy
    Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden Electronic address
    Am Heart J 168:325-31. 2014
    ..We aimed to assess the utility of the SHFM by validation in patients with CRT and/or ICD referred for heart transplantation...
  43. pmc Acylation of ghrelin is increased in heart failure and decreases post heart transplantation
    Stanislava Zabarovskaja
    Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Scand Cardiovasc J 48:343-8. 2014
    ..We tested the hypothesis that ghrelin derangements in HF are due to inadequate acylation and that this resolves post transplantation...
  44. doi request reprint Association between use of β-blockers and outcomes in patients with heart failure and preserved ejection fraction
    Lars H Lund
    Unit of Cardiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden2Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden
    JAMA 312:2008-18. 2014
    ..Heart failure with preserved ejection fraction (HFPEF) may be as common and may have similar mortality as heart failure with reduced ejection fraction (HFREF). β-Blockers reduce mortality in HFREF but are inadequately studied in HFPEF...
  45. doi request reprint Predicting survival in heart failure: validation of the MAGGIC heart failure risk score in 51,043 patients from the Swedish heart failure registry
    Ulrik Sartipy
    Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    Eur J Heart Fail 16:173-9. 2014
    ..The aim of this study was to evaluate the performance of a recently developed risk score for mortality in heart failure by external validation in a national heart failure registry...
  46. pmc Sex differences in response to maximal exercise stress test in trained adolescents
    Asa Fomin
    Department of Cardiology, Karolinska Institutet, Karolinska University Hospital, N1 05, SE 17176, Stockholm, Sweden
    BMC Pediatr 12:127. 2012
    ..Sex comparisons between girls and boys in response to exercise in trained adolescents are missing and we investigated similarities and differences as a basis for clinical interpretation and guidance...
  47. pmc Prevalence and prognostic impact of kidney disease on heart failure patients
    Ida Löfman
    Department of Medicine, Section of Cardiology, Huddinge, Sweden Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Open Heart 3:e000324. 2016
    ..We examined to what extent the different cardiac conditions and their severity contribute to the prognostic value of kidney dysfunction in heart failure...
  48. doi request reprint Survival After Coronary Artery Bypass Grafting in Patients With Preoperative Heart Failure and Preserved vs Reduced Ejection Fraction
    Magnus Dalén
    Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden2Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    JAMA Cardiol 1:530-8. 2016
    ..Data on the prognostic consequence of heart failure (HF) with preserved ejection fraction in patients undergoing coronary artery bypass grafting (CABG) are limited and inconclusive...
  49. doi request reprint Prognostic Significance of Resting Heart Rate and Use of β-Blockers in Atrial Fibrillation and Sinus Rhythm in Patients With Heart Failure and Reduced Ejection Fraction: Findings From the Swedish Heart Failure Registry
    Shi Jun Li
    From the Department of Medicine, Sahlgrenska University Hospital Ostra Hospital, Gothenburg, Sweden S J L, M F Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, China S J L Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden U S Department of Molecular Medicine and Surgery U S, Unit of Cardiology, Department of Medicine L H L, Karolinska Institute, Stockholm, Sweden Department of Cardiology and Department of Medical and Health Sciences, Linkoping University, Linkoping, Sweden U D and Centre for Applied Biostatistics, University of Gothenburg, Gothenburg, Sweden M A, M P
    Circ Heart Fail 8:871-9. 2015
    ..In heart failure and reduced ejection fraction, the prognostic role of heart rate (HR) in atrial fibrillation (AF) is unknown and the effectiveness of β-blockers has recently been questioned in AF...
  50. doi request reprint Awareness of indications for device therapy among a broad range of physicians: a survey study
    Clara Hübinette
    Department of Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden Department of Cardiology, Karolinska University Hospital, 171 76 Stockholm, Sweden
    Europace 16:1580-6. 2014
    ..We aimed to describe the awareness of indications for device therapy in a generalized sample of Swedish physicians...
  51. pmc Assessment of a University of California, Los Angeles 4-variable risk score for advanced heart failure
    Ulrik Sartipy
    Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden U S Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden U S
    J Am Heart Assoc 3:e000998. 2014
    ..However, the model has not been externally validated, and its suitability as a selection tool for heart transplantation (HT) and left ventricular assist device (LVAD) is unknown...
  52. doi request reprint Arterial-ventricular and interventricular interaction in isolated post-capillary and combined pulmonary hypertension in severe mitral stenosis
    Ashwin Venkateshvaran
    KTH School for Technology and Health, Royal Institute of Technology, Stockholm, Sweden
    Eur J Appl Physiol 116:1545-54. 2016
    ..Considering the discrepant RV load in Cpc-PH and Ipc-PH, we sought to investigate whether these two conditions are also characterized by differential alterations in AV coupling...
  53. pmc Heart failure and dementia: survival in relation to types of heart failure and different dementia disorders
    Pavla Cermáková
    Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division for Neurogeriatrics, Novum, Blickagången 6, 141 57, Huddinge, Sweden
    Eur J Heart Fail 17:612-9. 2015
    ..The aims were to (i) describe patients with HF and dementia, assess (ii) the proportion of specific dementia disorders in types of HF based on ejection fraction and (iii) the prognostic role of types of HF and dementia disorders...
  54. ncbi request reprint Predicting survival in ambulatory patients with severe heart failure on beta-blocker therapy
    Lars H Lund
    Department of Medicine, Columbia University, New York, New York, USA
    Am J Cardiol 92:1350-4. 2003
    ..The efficacy of these prognostic variables in patients receiving beta-blocker therapy was evaluated...
  55. ncbi request reprint Comparison of peak exercise oxygen consumption and the Heart Failure Survival Score for predicting prognosis in women versus men
    Philip Green
    Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
    Am J Cardiol 99:399-403. 2007
    ..The HFSS was consistent between genders. In conclusion, peak VO2 and the HFSS are excellent parameters to predict survival in women with congestive heart failure. THE HFSS is more consistent than the peak VO2 between the genders...