Chunlei Liu

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc High-field (9.4 T) MRI of brain dysmyelination by quantitative mapping of magnetic susceptibility
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, NC 27705, USA
    Neuroimage 56:930-8. 2011
  2. pmc Probing white-matter microstructure with higher-order diffusion tensors and susceptibility tensor MRI
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University Durham, NC, USA Department of Radiology, Duke University Durham, NC, USA
    Front Integr Neurosci 7:11. 2013
  3. pmc Imaging neural architecture of the brain based on its multipole magnetic response
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, NC, USA
    Neuroimage 67:193-202. 2013
  4. pmc 3D fiber tractography with susceptibility tensor imaging
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, 2424 Erwin Rod, Suite 501, Durham, NC 27705, USA
    Neuroimage 59:1290-8. 2012
  5. pmc In vivo generalized diffusion tensor imaging (GDTI) using higher-order tensors (HOT)
    Chunlei Liu
    Brain Imaging and Analysis Center, Duke University, Durham, North Carolina 27705, USA
    Magn Reson Med 63:243-52. 2010
  6. pmc Auto-calibrated parallel imaging reconstruction for arbitrary trajectories using k-space sparse matrices (kSPA)
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, NC 27705, USA
    IEEE Trans Med Imaging 29:950-9. 2010
  7. pmc Susceptibility tensor imaging
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, North Carolina 27705, USA
    Magn Reson Med 63:1471-7. 2010
  8. pmc Magnetic susceptibility anisotropy of human brain in vivo and its molecular underpinnings
    Wei Li
    Brain Imaging and Analysis Center, Department of Biomedical Engineering, School of Medicine, Duke University, Durham, NC 27705, USA
    Neuroimage 59:2088-97. 2012
  9. pmc Imaging whole-brain cytoarchitecture of mouse with MRI-based quantitative susceptibility mapping
    Hongjiang Wei
    Brain Imaging and Analysis Center, Duke University, Durham, NC 27705, USA
    Neuroimage 137:107-15. 2016
  10. pmc Magnetic susceptibility of brain iron is associated with childhood spatial IQ
    Kimberly L H Carpenter
    Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA Electronic address
    Neuroimage 132:167-74. 2016

Collaborators

Detail Information

Publications33

  1. pmc High-field (9.4 T) MRI of brain dysmyelination by quantitative mapping of magnetic susceptibility
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, NC 27705, USA
    Neuroimage 56:930-8. 2011
    ..More importantly, the present study suggests that quantitative magnetic susceptibility is a potential endogenous biomarker for myelination...
  2. pmc Probing white-matter microstructure with higher-order diffusion tensors and susceptibility tensor MRI
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University Durham, NC, USA Department of Radiology, Duke University Durham, NC, USA
    Front Integr Neurosci 7:11. 2013
    ..It is believed that diffusion MRI and susceptibility MRI provide complementary information of the microstructure of white matter. Together, they allow a more complete assessment of healthy and diseased brains...
  3. pmc Imaging neural architecture of the brain based on its multipole magnetic response
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, NC, USA
    Neuroimage 67:193-202. 2013
    ..These experiments demonstrate that multipole tensor analysis may enable practical mapping of tissue microstructure in vivo without rotating subject or magnetic field...
  4. pmc 3D fiber tractography with susceptibility tensor imaging
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, 2424 Erwin Rod, Suite 501, Durham, NC 27705, USA
    Neuroimage 59:1290-8. 2012
    ..As STI tractography is based on physical principles that are fundamentally different from DTI, it may also be valuable for the ongoing validation of DTI tractography...
  5. pmc In vivo generalized diffusion tensor imaging (GDTI) using higher-order tensors (HOT)
    Chunlei Liu
    Brain Imaging and Analysis Center, Duke University, Durham, North Carolina 27705, USA
    Magn Reson Med 63:243-52. 2010
    ..Furthermore, through bootstrap analysis we demonstrate that in vivo measurement of HOT elements is reproducible, with a small statistical variation that is similar to that of diffusion tensor imaging...
  6. pmc Auto-calibrated parallel imaging reconstruction for arbitrary trajectories using k-space sparse matrices (kSPA)
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, NC 27705, USA
    IEEE Trans Med Imaging 29:950-9. 2010
    ..In practice, because of its higher SNR, calibration data acquired at the center of k-space performed more favorably. Such auto-calibration can be advantageous in cases where an accurate sensitivity map is difficult to obtain...
  7. pmc Susceptibility tensor imaging
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, North Carolina 27705, USA
    Magn Reson Med 63:1471-7. 2010
    ..We believe that this network may further offer information of white matter fiber orientation...
  8. pmc Magnetic susceptibility anisotropy of human brain in vivo and its molecular underpinnings
    Wei Li
    Brain Imaging and Analysis Center, Department of Biomedical Engineering, School of Medicine, Duke University, Durham, NC 27705, USA
    Neuroimage 59:2088-97. 2012
    ....
  9. pmc Imaging whole-brain cytoarchitecture of mouse with MRI-based quantitative susceptibility mapping
    Hongjiang Wei
    Brain Imaging and Analysis Center, Duke University, Durham, NC 27705, USA
    Neuroimage 137:107-15. 2016
    ..Olfactory glomerulus density is calculated and structural connectivity is traced in the optic nerve, striatal neurons, and brainstem nerves. The method is robust and can be readily applied on MRI scanners at or above 7T. ..
  10. pmc Magnetic susceptibility of brain iron is associated with childhood spatial IQ
    Kimberly L H Carpenter
    Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA Electronic address
    Neuroimage 132:167-74. 2016
    ..This provides a potential neurobiological mechanism linking deficits in spatial abilities reported in children who were severely iron deficient as infants to decreased iron within the caudate. ..
  11. pmc Association between increased magnetic susceptibility of deep gray matter nuclei and decreased motor function in healthy adults
    Wei Li
    Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC 27710, USA Research Imaging Institute, University of Texas Health Science Center at San Antonio, TX 78229, USA Department of Ophthalmology, University of Texas Health Science Center at San Antonio, TX 78229, USA
    Neuroimage 105:45-52. 2015
    ..This finding suggests the potential value of magnetic susceptibility, a non-invasive quantitative imaging marker of iron, for the study of iron-related brain function changes...
  12. pmc Susceptibility tensor imaging of the kidney and its microstructural underpinnings
    Luke Xie
    Center for In Vivo Microscopy, Department of Radiology, Duke University Medical Center, Durham, North Carolina, USA Department of Biomedical Engineering, Duke University, Durham, North Carolina, USA
    Magn Reson Med 73:1270-81. 2015
    ..The purpose of this study was to determine whether susceptibility tensor imaging (STI) could overcome limitations of current techniques to detect tubules throughout the kidney...
  13. pmc Whole brain susceptibility mapping using compressed sensing
    Bing Wu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, North Carolina, USA
    Magn Reson Med 67:137-47. 2012
    ..The correlation between the iron content and the susceptibility levels in iron-rich deep nucleus regions is studied, and strong linear relationships are observed which agree with previous findings...
  14. pmc Quantitative susceptibility mapping of human brain reflects spatial variation in tissue composition
    Wei Li
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, NC 27705, USA
    Neuroimage 55:1645-56. 2011
    ..Further elucidation of anisotropic magnetic susceptibility in vivo may allow us to gain more insight into the white matter micro-architectures...
  15. pmc Magnetic susceptibility anisotropy outside the central nervous system
    Russell Dibb
    Center for In Vivo Microscopy, Department of Radiology, Duke University Medical Center, Durham, NC, USA
    NMR Biomed . 2016
    ..This paper reviews essential experimental findings of susceptibility anisotropy in the body, the underlying mechanisms, and the associated MRI methodologies. Copyright © 2016 John Wiley & Sons, Ltd...
  16. doi request reprint Joint 2D and 3D phase processing for quantitative susceptibility mapping: application to 2D echo-planar imaging
    Hongjiang Wei
    Brain Imaging and Analysis Center, Duke University, Durham, NC, USA
    NMR Biomed . 2016
    ..This new 2D EPI QSM reconstruction method is implemented within STI Suite, which is a comprehensive shareware for susceptibility imaging and quantification. Copyright © 2016 John Wiley & Sons, Ltd...
  17. doi request reprint Investigating magnetic susceptibility of human knee joint at 7 tesla
    Hongjiang Wei
    Brain Imaging and Analysis Center, Duke University, Durham, NC 27708, USA
    Magn Reson Med . 2017
    ..To evaluate the magnetic susceptibility properties of different anatomical structures within the knee joint using quantitative susceptibility mapping (QSM)...
  18. pmc A method for estimating and removing streaking artifacts in quantitative susceptibility mapping
    Wei Li
    Brain Imaging and Analysis Center, Duke University, Durham NC 27705, USA Research Imaging Institute, University of Texas Health Science Center at San Antonio, TX 78229, USA Department of Ophthalmology, University of Texas Health Science Center at San Antonio, TX 78229, USA Electronic address
    Neuroimage 108:111-22. 2015
    ..The proposed methodology can be extended to other existing QSM algorithms. ..
  19. pmc Integrated Laplacian-based phase unwrapping and background phase removal for quantitative susceptibility mapping
    Wei Li
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, NC, USA
    NMR Biomed 27:219-27. 2014
    ..The proposed algorithm is provided, together with QSM and susceptibility tensor imaging (STI) tools, in a shared software package named 'STI Suite'...
  20. pmc Fast and tissue-optimized mapping of magnetic susceptibility and T2* with multi-echo and multi-shot spirals
    Bing Wu
    Brain Imaging and Analysis Center, Duke University, Durham NC 27705, USA
    Neuroimage 59:297-305. 2012
    ..The technique can be readily extended to other multi-shot readout trajectories besides spiral. It may provide a practical acquisition strategy for high resolution and simultaneous 3D mapping of magnetic susceptibility and T2*...
  21. pmc Quantitative Susceptibility Mapping: Contrast Mechanisms and Clinical Applications
    Chunlei Liu
    Brain Imaging and Analysis Center, Duke University School of Medicine, Durham, NC 27710 Department of Radiology, Duke University School of Medicine, Durham, NC 27710 Center for In Vivo Microscopy, Duke University School of Medicine, Durham, NC 27710
    Tomography 1:3-17. 2015
    ..This article reviews the mechanism generating susceptibility contrast within tissues and some associated applications...
  22. pmc Magnetic susceptibility anisotropy of myocardium imaged by cardiovascular magnetic resonance reflects the anisotropy of myocardial filament α-helix polypeptide bonds
    Russell Dibb
    Center for In Vivo Microscopy, Duke University Medical Center, Box 3302, Durham, NC, 27710, USA
    J Cardiovasc Magn Reson 17:60. 2015
    ..Studies suggest that striated muscle fibers are magnetically anisotropic, which, if measurable in the heart, may provide a tool to assess myocardial microstructure and function...
  23. pmc Streaking artifact reduction for quantitative susceptibility mapping of sources with large dynamic range
    Hongjiang Wei
    Brain Imaging and Analysis Center, Duke University, Durham, NC, USA
    NMR Biomed 28:1294-303. 2015
    ..STAR-QSM is implemented in STI Suite, a comprehensive shareware for susceptibility imaging and quantification...
  24. pmc Differential developmental trajectories of magnetic susceptibility in human brain gray and white matter over the lifespan
    Wei Li
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, North Carolina
    Hum Brain Mapp 35:2698-713. 2014
    ..Our results suggest that magnetic susceptibility may provide valuable information regarding the spatial and temporal patterns of brain myelination and iron deposition during brain maturation and ageing...
  25. pmc Quantitative susceptibility mapping of kidney inflammation and fibrosis in type 1 angiotensin receptor-deficient mice
    Luke Xie
    Center for In Vivo Microscopy, Department of Radiology, Duke University Medical Center, Durham, NC, USA Department of Biomedical Engineering, Duke University, Durham, NC, USA
    NMR Biomed 26:1853-63. 2013
    ..QSM was very sensitive in detecting pathology caused by small focal inflammation and fibrosis. QSM offers a new MR contrast mechanism to study this common disease marker in the kidney...
  26. pmc Feasibility of Imaging Tissue Electrical Conductivity by Switching Field Gradients with MRI
    Eric Gibbs
    Brain Imaging and Analysis Center, Duke University School of Medicine, Durham, NC 27710
    Tomography 1:125-135. 2015
    ..The animal scanner images show no measurable phase accumulation. Measuring low-frequency conductivity by gradient-induced eddy currents is presently unfeasible...
  27. doi request reprint Joint eigenvector estimation from mutually anisotropic tensors improves susceptibility tensor imaging of the brain, kidney, and heart
    Russell Dibb
    Center for In Vivo Microscopy, Duke University Medical Center, Durham, NC, USA
    Magn Reson Med . 2016
    ....
  28. pmc Susceptibility-weighted imaging and quantitative susceptibility mapping in the brain
    Chunlei Liu
    Brain Imaging and Analysis Center, School of Medicine, Duke University, Durham, North Carolina, USA
    J Magn Reson Imaging 42:23-41. 2015
    ..This article reviews the basic principles of SWI, its clinical and research applications, the mechanisms governing brain susceptibility properties, and its practical implementation, with a focus on brain imaging...
  29. pmc Prenatal alcohol exposure reduces magnetic susceptibility contrast and anisotropy in the white matter of mouse brains
    Wei Cao
    Brain Imaging and Analysis Center, Duke University, Durham, NC, United States Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Neuroimage 102:748-55. 2014
    ..Our data also suggested that QSM may be even more sensitive than DTI for examining changes due to prenatal alcohol exposure. Although this is a preclinical study, the technique of QSM is readily translatable to human brain. ..
  30. pmc The Alzheimer structural connectome: changes in cortical network topology with increased amyloid plaque burden
    Jeffrey W Prescott
    From the Department of Radiology J W P, K R C, J P, Department of Psychiatry P M D, Department of Medicine P M D, and Duke Institute for Brain Sciences P M D, Duke University Medical Center, Box 3808, Durham, NC 27710 and Brain Image Analysis Center, Duke University, Durham, NC A G, C L
    Radiology 273:175-84. 2014
    ....
  31. pmc Microstructural origins of gadolinium-enhanced susceptibility contrast and anisotropy
    Russell Dibb
    Center for In Vivo Microscopy, Duke University Medical Center, Durham, North Carolina, USA Biomedical Engineering, Duke University, Durham, North Carolina, USA
    Magn Reson Med 72:1702-11. 2014
    ..Characterizing the effect of these tools will aid in assessing white matter myelin content and microstructure...
  32. pmc Effects of chronic mild traumatic brain injury on white matter integrity in Iraq and Afghanistan war veterans
    Rajendra A Morey
    Duke UNC Brain Imaging and Analysis Center, Duke University Medical Center, Durham, North Carolina Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina Mental Illness Research Education and Clinical Center for Post Deployment Mental Health, Durham VA Medical Center, Durham, North Carolina
    Hum Brain Mapp 34:2986-99. 2013
    ..The diffuse loss of white matter integrity appears consistent with systemic mechanisms of damage shared by blast- and impact-related mild TBI that involves a cascade of inflammatory and neurochemical events...
  33. pmc Correlation of apparent diffusion coefficient and fractional anisotropy values in the developing infant brain
    James M Provenzale
    Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA
    AJR Am J Roentgenol 195:W456-62. 2010
    ..The purpose of our study was to correlate decrease in apparent diffusion coefficient (ADC) and increase in fractional anisotropy (FA) in various white matter (WM) regions using diffusion tenor imaging (DTI) within the first year of life...